Basic Information

Insect: Bombus hortorum
Gene Symbol: ZFX
Assembly: GCA_905332935.1
Location: HG995193.1:10574078-10578495[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.1 1.2e+02 3.7 0.1 3 23 24 44 23 44 0.94

2 15 5.2 5.6e+02 1.6 4.2 1 23 904 927 904 927 0.80

3 15 0.0002 0.021 15.5 1.9 3 23 1012 1033 1010 1033 0.96

4 15 0.012 1.3 9.9 0.5 2 23 1046 1067 1045 1067 0.97

5 15 1.4e-05 0.0015 19.2 3.1 2 23 1070 1091 1069 1091 0.97

6 15 0.0017 0.18 12.6 0.5 1 23 1097 1119 1097 1119 0.96

7 15 2.2e-05 0.0024 18.5 4.5 2 23 1126 1147 1125 1148 0.95

8 15 0.099 11 7.0 3.7 5 23 1161 1179 1160 1179 0.97

9 15 2e-05 0.0021 18.7 1.5 3 23 1186 1207 1185 1207 0.97

10 15 0.016 1.7 9.5 0.3 2 23 1223 1243 1222 1243 0.97

11 15 6e-05 0.0064 17.1 0.7 1 20 1249 1268 1249 1271 0.92

12 15 0.00022 0.023 15.4 2.7 1 23 1279 1301 1279 1301 0.99

13 15 0.0021 0.22 12.3 3.2 1 23 1307 1329 1307 1329 0.97

14 15 3.8e-06 0.00041 20.9 3.9 1 23 1335 1357 1335 1357 0.99

15 15 0.0013 0.14 12.9 6.3 1 23 1363 1385 1363 1386 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.1	1.2e+02	3.7	0.1	3	23	24	44	23	44	0.94
2	15	5.2	5.6e+02	1.6	4.2	1	23	904	927	904	927	0.80
3	15	0.0002	0.021	15.5	1.9	3	23	1012	1033	1010	1033	0.96
4	15	0.012	1.3	9.9	0.5	2	23	1046	1067	1045	1067	0.97
5	15	1.4e-05	0.0015	19.2	3.1	2	23	1070	1091	1069	1091	0.97
6	15	0.0017	0.18	12.6	0.5	1	23	1097	1119	1097	1119	0.96
7	15	2.2e-05	0.0024	18.5	4.5	2	23	1126	1147	1125	1148	0.95
8	15	0.099	11	7.0	3.7	5	23	1161	1179	1160	1179	0.97
9	15	2e-05	0.0021	18.7	1.5	3	23	1186	1207	1185	1207	0.97
10	15	0.016	1.7	9.5	0.3	2	23	1223	1243	1222	1243	0.97
11	15	6e-05	0.0064	17.1	0.7	1	20	1249	1268	1249	1271	0.92
12	15	0.00022	0.023	15.4	2.7	1	23	1279	1301	1279	1301	0.99
13	15	0.0021	0.22	12.3	3.2	1	23	1307	1329	1307	1329	0.97
14	15	3.8e-06	0.00041	20.9	3.9	1	23	1335	1357	1335	1357	0.99
15	15	0.0013	0.14	12.9	6.3	1	23	1363	1385	1363	1386	0.96

Sequence Information

Coding Sequence: ATGTATAAAGAAAATACCTCAGACATAATGGATGCAGTAAGCAATGGAGCTTCAGGAAGTGCAGTGGCTTGTCCAGTTTGTACCCTCTATCTACGCGAGGGTATCAGCTTACAAAGACATTTGGATACTCATCCAAAAGAACAAGTCATTGAAGCTCTTATCAAAGCTAGTACCAATTCCTCAAATGTGCAACAGATACAGTTATCATCATCAGTACCTCCAGTATCTCCAGCTATACAATCCCAAAATACACCTCAAATTGCACAGAATACTCATCTATCGGCTCAATCTCCATATCCTATAGGACCTATTTTCGAATGTCCACCTATCGGTACTGTGATGCCACCTCAATTTGCTTCATTTAGTTATCAACAGTTTGTAAATAATGGCACTATGATGATACCACAATATGCAATGGCTCCACAAGCTAATCAAATGATGCAAATGCTGTATAATCCATATGGTATGTATCAGCAACAACAAATACCAACTGTTCAAATGATTTCGCCAGTCACAGCCATACCAAACACCACTAGAGTCAGGCCAGTGGTAACTATGACTGGTGAAACAACTGGTAGAACTGCCATTGCTGTACCTGTAAATAATTCCGAGCCAAAACAAATTTTACCTGAGATTTTACCTGAATCAGAGCAAGAGTCTGAACAGATGTTATCAGATATCAACCTTCCAGTTTCTCCTCCATCATTAAACGAAGATAATTCTATGCAGCAAAATGAAAGTGAAACTAGTACAATTCAAATAGAGCAAGAAGGAGAGGAGCCCCTTGGTTCAAGTACAGATCAGCATACTGTGCAAGATGAATATGATAGCATTCCAAGATCATTGGCAATTACTTGTAATGTCAATGTCACTACAGATGATAAAGTTGAGAGTGTATTGCCGGATATTGATAATGGGGAATCATCGTGCGTTGTTACTACAAATGTGCAGTGTAAGTCTATTCATTATGAATCGTCAGAAATGCAGGAGTATGTACACAGATATGAAGATGATGATGATAATAATAAAGTTATTATGCCTGAAGTATCACCAATGGTAACACAAAATGAGACAGAAAATGCAACTAATGAAAAAGTTCCTCACAGAGAAGAAATAAGCAAAAATGAAGGTACCTCAGCAGAAATGCCTGTAGAAGATACAGTAAAAGCACCAGCTCAACCTGAAGTAGAACAATTAGAATGTCTTTTAATCACTATTGTGGAAAATGAATTTAATAATAATCCACAGAAAGAATCCAATTTTGAAGATGATAAAAAAAAGAATAAAGATACAAAGAAAAATACTTCTCCTGAAAGGGCTGAAAGTGTAATACATGAAATAACTAGTAATAATCCCATTGAATATGAAAACAGTTGTAAATCTGATGTAAAAGTAAAAGTTAATCAAAGTTCGGAAATTAATATAAGTAATGATGAAAATAAAAGTTCTTGTCTTTTATACAATTATAAAAACAGTTTGTCTGCACCTCCATCACCTATTGTACAAAGAAGACCCCATAGAACCTATTCTGTTCATTCAGATTTTAGTTCAAATGAACACCTTAATTTTTATCCAATTGGTTTTGATGCAAGCACATTGCATGATGAGGAAGAAGATGATGAAGATGATGAAGATGAAGAAGATGAAGAAGATGAAGATGAAAAAAATGAAACAGAAGATAATTTTGATGAAGCAGATATGGAAATAGAGGAAATACCTAGCCCACATACTCCTTTCATTAAATATGATGAAAATGCAGACAATGTTAGATCTCATACTCCGTTATCTGCAAGTAGTGGTATTTCTGTATTAAGAGTTAGGAAGGATCTTAGTAAACCATGTTCACCTGCTTCTGTCCATTCATTTTGTCATATGGATGCTAATGGTATAAGCCATGACGAAGAAAGTAATGTAGCAATGGATGAATCGCCAGAAAAAGATTCTATTGATTGTTCTTTAGTTGAACAAGATGTGAAAGCTGATCACTCAGAGCTTTCCTTATGTAAAAATGAGAAAAAAATGGAAGGAGGTTCTGCATATCAATCTGGAATTAGTGACCATATGAGTTCGTTTTCTACAATTCATTCACAACATTCTCAGCAATCAACGTTAATAAATGAATCATATAACATGCCAAGTAAAAGTAATAATCATGTAAATTTATTAGAATCTAGTGATGTTGCAAGTAGTTCTGACTCAAAGAGTTTTCATTCATCTAAATCAATTATACAAAAACAATCTGTGGAACTTCTTAGTTTAAATGAAGATGCCCATGCAGGTCCAATGAATGTGTTTGAATTTGATGGGCTTCAAATCTTAGTTCCTAGTACATTCATAAGTGATTCTTCACAAAAAGCAGTTAGTGGAACCAGCCAACAATCTATGGCAAGTAGTGAAGGTGGAATAGGTATAGATGAAGAAGTTAAAAGCATTAATATGAGAGCTGATGAAACTATGCCAGCCAGAGGTGAACTATCAGAACAAGAAAGCAATGGATGTACAGAACAATCAGCTTGGCAGTTATATGCTGGTCAAGAATCATCAAGAATGTCAACATCTTATGATCTAATGGCACGTGAAAGTTGGGAAGAATCTGATGGATCAGACAATGAAATTACAGGCCCATTATTAGATAGCAGATCTTTAGCAACACATTTTACATCAAGTTTATTTTTAGATCGAGATAGAAAAACTCCTACAAAAATAATGTTCAAATGTTATCATTGCCCTGAAGTATTTGATTGTCCGAAAGAACGCAGAGTACATAGTACCACCACGCACAAAGAAGCTGGTCCGAGTAGCAGTAGAGAATCTACAGAACAACCTGAAGTAAAAGATATTAAGTTATTGGATGGCCGTATGAATGTATTTGAAGATATTTTTGTACCAGGTTTACATATTCAACAAGTTTATCACCAGCCACCACTGTTACATCAACTTCAACCACCACAATCATGTACAGATGTAACTACAAAAGTAGAATCTGATGAAAAAATTGAAACACTAGTAATACCATCAAACATTGAAGTGATCTGCACCCTTTGCAATCAGACATTTAGCAGTGAAAAATCATTACAGCTACATCATAGAAGAGCACATATTACAGAAACAACAAAACGAATTCGTGAGAGCACCAAGTGTCAGATATGTCACGAAGAATTTCCTTCTGTTCTATTGTACAATGCCCATTTAAAAATACATCCATTAGAATGTAGTCAATGTGGAAAGTATTTTTATAGAAAGCAAAATTTTAAATTACATATGAAACGACATTTAGGAATTAAACCATTTCCATGTACTGTTTGTGACAAAGCATTTTTAACAAAACAGAAGTTAAATGAACATACTAATGGTCATACTGGGAATGCACCTGTTAAGTGTAATCTTTGCAATGAAACATTTCGCAGATATTCAAATCTAACACAGCACAAAAATAGACATCATTTGAATATAAAAAAGAAATTAAAAGATTACATATGTCATTGTGGTGAGGTTTTTCATACAAAGAAAAAGCTAGCTTGGCATAAAGAAACACATGATGAAAAACCCAAAGCATGTACATATTGTAACGAAAGATTCATTCACATGGCCAGCCTGACTAGACATATGCGCCGAGCTCATAATAAAAGATTCGTTCCAGATGCTCAAAGAGAGAGCGAAAATGTTGAATGTCCTGTATGTAAGTGTATTTATTTACGATCTTCCTTAGCAGTGCATATGCGAGTACATAATGGTGAAAGACCATATGAATGTCAAGTTTGCTCTAAAGCATTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACTCACGCTGCTCGTAGCACCAAACCTTACAAGTGTAATCAGTGTAGTGGTGCGTTTTATCGGCACAGTGATTATACTGCTCATATGAATTCTCATAAAAACGTGCGTCCTTATACCTGTAACTATTGCGGAGCGCAGTTCATACGAAAATATAATTGTTTAAGGCATGTAAAGGAACATGAAGAGAACAAAGCATATACATGTGATGTTTGCAACAAAACTTTTCATAGATCATATTATCTGAAAGAACACTTGCGAGTACATTCAGGTGCCAGACCATATACATGTCATATTTGTGGAAAGTCTAGCGGTACGAAATCCAATCATAACAAACATGTCAGAATTCATCATGCACGAGAACCTGTAAATACCGAAAATTAA
Protein Sequence: MYKENTSDIMDAVSNGASGSAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASTNSSNVQQIQLSSSVPPVSPAIQSQNTPQIAQNTHLSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTAIPNTTRVRPVVTMTGETTGRTAIAVPVNNSEPKQILPEILPESEQESEQMLSDINLPVSPPSLNEDNSMQQNESETSTIQIEQEGEEPLGSSTDQHTVQDEYDSIPRSLAITCNVNVTTDDKVESVLPDIDNGESSCVVTTNVQCKSIHYESSEMQEYVHRYEDDDDNNKVIMPEVSPMVTQNETENATNEKVPHREEISKNEGTSAEMPVEDTVKAPAQPEVEQLECLLITIVENEFNNNPQKESNFEDDKKKNKDTKKNTSPERAESVIHEITSNNPIEYENSCKSDVKVKVNQSSEINISNDENKSSCLLYNYKNSLSAPPSPIVQRRPHRTYSVHSDFSSNEHLNFYPIGFDASTLHDEEEDDEDDEDEEDEEDEDEKNETEDNFDEADMEIEEIPSPHTPFIKYDENADNVRSHTPLSASSGISVLRVRKDLSKPCSPASVHSFCHMDANGISHDEESNVAMDESPEKDSIDCSLVEQDVKADHSELSLCKNEKKMEGGSAYQSGISDHMSSFSTIHSQHSQQSTLINESYNMPSKSNNHVNLLESSDVASSSDSKSFHSSKSIIQKQSVELLSLNEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSGTSQQSMASSEGGIGIDEEVKSINMRADETMPARGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESDGSDNEITGPLLDSRSLATHFTSSLFLDRDRKTPTKIMFKCYHCPEVFDCPKERRVHSTTTHKEAGPSSSRESTEQPEVKDIKLLDGRMNVFEDIFVPGLHIQQVYHQPPLLHQLQPPQSCTDVTTKVESDEKIETLVIPSNIEVICTLCNQTFSSEKSLQLHHRRAHITETTKRIRESTKCQICHEEFPSVLLYNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLNEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNKRFVPDAQRESENVECPVCKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPYKCNQCSGAFYRHSDYTAHMNSHKNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_00215196;
80% Identity: -