Basic Information

Insect: Apis mellifera
Gene Symbol: ZFX
Assembly: GCA_003254395.2
Location: NC:24271485-24277741[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.85 52 3.7 0.1 3 23 24 44 23 44 0.94

2 15 2.1 1.3e+02 2.5 3.4 1 23 892 915 892 915 0.80

3 15 0.00017 0.01 15.3 1.8 3 23 999 1020 997 1020 0.96

4 15 0.0066 0.4 10.4 0.6 2 23 1033 1054 1032 1054 0.97

5 15 1e-05 0.00063 19.2 3.1 2 23 1057 1078 1056 1078 0.97

6 15 0.0085 0.52 10.0 0.3 1 23 1084 1106 1084 1106 0.95

7 15 1.7e-05 0.001 18.5 4.5 2 23 1113 1134 1112 1135 0.95

8 15 0.075 4.5 7.0 3.7 5 23 1148 1166 1147 1166 0.97

9 15 1.5e-05 0.00092 18.7 1.5 3 23 1173 1194 1172 1194 0.97

10 15 0.012 0.75 9.5 0.3 2 23 1210 1230 1209 1230 0.97

11 15 2.8e-05 0.0017 17.8 1.2 1 20 1236 1255 1236 1258 0.92

12 15 0.00024 0.014 14.9 2.8 1 23 1266 1288 1266 1288 0.99

13 15 0.0016 0.097 12.3 3.2 1 23 1294 1316 1294 1316 0.97

14 15 2.9e-06 0.00018 20.9 3.9 1 23 1322 1344 1322 1344 0.99

15 15 0.00099 0.061 12.9 6.3 1 23 1350 1372 1350 1373 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.85	52	3.7	0.1	3	23	24	44	23	44	0.94
2	15	2.1	1.3e+02	2.5	3.4	1	23	892	915	892	915	0.80
3	15	0.00017	0.01	15.3	1.8	3	23	999	1020	997	1020	0.96
4	15	0.0066	0.4	10.4	0.6	2	23	1033	1054	1032	1054	0.97
5	15	1e-05	0.00063	19.2	3.1	2	23	1057	1078	1056	1078	0.97
6	15	0.0085	0.52	10.0	0.3	1	23	1084	1106	1084	1106	0.95
7	15	1.7e-05	0.001	18.5	4.5	2	23	1113	1134	1112	1135	0.95
8	15	0.075	4.5	7.0	3.7	5	23	1148	1166	1147	1166	0.97
9	15	1.5e-05	0.00092	18.7	1.5	3	23	1173	1194	1172	1194	0.97
10	15	0.012	0.75	9.5	0.3	2	23	1210	1230	1209	1230	0.97
11	15	2.8e-05	0.0017	17.8	1.2	1	20	1236	1255	1236	1258	0.92
12	15	0.00024	0.014	14.9	2.8	1	23	1266	1288	1266	1288	0.99
13	15	0.0016	0.097	12.3	3.2	1	23	1294	1316	1294	1316	0.97
14	15	2.9e-06	0.00018	20.9	3.9	1	23	1322	1344	1322	1344	0.99
15	15	0.00099	0.061	12.9	6.3	1	23	1350	1372	1350	1373	0.96

Sequence Information

Coding Sequence: atgtataaacaaaataCCTCAGGCATAATGGATACAACAAACAATGGAGCATCAGGAGGTGCAGTGGCTTGTCCAGTATGCACTCTTTATCTACGTGAGGGTATTAGCTTACAAAGACATTTGGACACTCATCCAAAAGAACAAGTTATTGAAGCTCTTATTAAAGCTAGTAACAATGCCTCACAAGTGCATCAGGCACAATTGTCATCATCAGTACCTCCAGCATCTCCAGCTATGCAATCACCCCAAAATACACCTCAAGTTGCACAGAATACTCATCTATCAGCTCAATCTCCATATCCTATAGGACCTATTTTTGAGTGTCCACCTATTGGTACTGTGATGCCACCTCAGTTTGCTTCATTTAGTTATCAACAGTTTGTAAATAATGGCACTATGATGATACCACAATACGCAATGGCTCCACAAGCTAATCAAATGATGCAAATGCTTTATAATCCATATGGTATGTACCAGCAGCAACAAATACCAACTGTTCAAATGATTTCACCAGTCACAGCCATACCTAATTCAGCTAGAGTCAGGCCAGTAATGACTATGGCTGGTGAAACAAATGGTAGAACTGCCATTGCTGTACCTGTAAATAATTCCGAGCCAAAACAAATTTTACCTGAGATTTTACCTGAATCAGAACAGGAGTCTGAGCAAGTGTTACCAGATATTAATCTTCCAGTTTCTCCTCCATCATTAAATGAAGATAACTCTATGCAGCAAAATGAAAGTGAAACTAGTACAATTCAAATAGATCAAGAAGTAGAAGAATCCCATAATTCAAGTACTTCAGAGCAACATACTGTGCAAAATGAATATGATAACATTCCAAGATCAGTGACAATTACTTGTAATGTCAATGATACTACAGATGATAAAGTTGAGAGTGTATTGCCAGATATTGATGATGGAGAATCATCATGTGTTGTTACTACAGATGTACAATGTAAATCTCTTCATTATGAAGCATCAGAAATACAAGGATATGTACACAGATAtgaagatgatgatgataacaataaaattattacgccTGAAGTATCTTCAATGATAACAGAAAATGAGATTGAAAAAGCAACTAATGAAAAAGTTCCTCacagagaagaaataaatgaaaatgaaggtACCTCTGCAGAAATGCCCTTAGAAGATACAGTAAAGGCACCAGCTCAGCGTGAAGTAGAACAATTAGAACGTCTTTTAATCACTATTATGGAAAATGAGTTTAATAATACACCGCAAAAAGAATCTAATTCTgaagatgataaaaagaatgaagGTACAAAGAAAAGTCTTTCTCCTAAAAGAGCAGAAAGTGTAATTCATGAAACAATCAGTAATAATTCCATTGAGCATGAACATAGTTGTGAatctgatataaaaataaaacttagtGAAAGTTCAGAAATTGATATagataatgatgaaaataaaagttctTGTCTTTCAtaccattataaaaatagtttatctGCACCTGCATCACCAATTGTACGAAAGAGACCTCATAGAACTTACTCAGTTCGTTCAGAATTTAGTTCAAatgaaaatcttaatttttatccaaatagTTTTGATGCAAATACATTACAAGATGAAGAAGATgatgaagatgaaaaaaatgaagcagaagataattttgatgaaGCAGATatggaaatagaagaaataccTAGCCCACATACTCCTTTCATTAAATATGGTGAAAATGGAGACAATGTTAGATCACATACTCCATTATCTGCAAGTAGTGGTATATCTGTATTAAGAGTTCGAAAAGATCTTAGTAAACCATGTTCACCTGCATCAGTGCATTCATTTTGTCATATGGATACAAATGGTTTAAGTAATGATGAAGATAGTAATGGAGCAATGGATGAATCACCAGAAAAGGATCCTATTGATTGTTCTCAGGTTGAACAAGATGTAAAAACTGATCATTTAGAACTTTCTAtatgtgaaaatgaaaaaaaaatggaaggaaaTTCTGCATATCAATCTGGAATTACTGAACATATAAGTTCATTTTCTACAATTCATTCACAACATTCTCAGCAATCAATATCAATGGTGGATTCATATAATATGCCAAATAAAagtaatcatataaatttatcagaatCTAATGATGTTGCAAGTAGTTCTgattcaaagaattttcattcatctaAATCAATTATACAAAAGCAATCAGTGGAACTTCTTAGTTTAAATGAAGATGCCCATGCAGGTCCAATGAATGTATTTGAATTTGATGGGCTTCAAATCTTAGTTCCTAGTACATTCATAAGTGATTCTTCACAAAAAGCAGTTAGTGGAACCAGCCAACAATCTATGGCAAGTAGTGAAGGTGGAGTAGGTGTAGATGAAGAagttaaaagtattaatatgaGAGCTGATGAAACTATGCCTCCCAGAGGTGAACTATCAGAACAAGAAAGCAATGGATGTACAGAACAATCTGCTTGGCAGTTGTATGCTGGTCAAGAATCATCACGAATGTCAACATCTTATGATTTAATGGCACGTGAAAGTTGGGAAGAATCTGATGGATCAGATAATGAAGTTGCAGGCCCCCTATTAGATAGCAGATCTTTAGCTACACATTTTACATcaagtttatttttagatcGAGATAGAAAAACTCCTACAAAAAGAATGTTTAAATGTTATCATTGTCCTGAAGTATTTGATTGCCCTAAAGAACGCCGAGTACATAGTACTACCGCGCACAAAGAAGCTGGACCGAGTAGTAGTAGAGAATCTACAGATCAACCTGAAGTAAAAGATATTAAGTTATTGGATGGTCGTATGAATGcatttgaagatatttttgtaCCAGGTTTACATGTTCAACAAGTTTATCATCAACAACCAATGTTACATCAACTTCAACCACCACAATCATCTGATGTAATTACAAAAGTAGAATCTGATCAAAAAGTTGAAACACTCGTAATACCATCAAATATTGAAGTAATTTGCACAGTTTGCAATCAACGATTTAGTAGTGAAAAATCATTACAACTACATCATAGAAGAGTACATGTTACAGAACCAACAAAGCGAATCCGTGAGAGCACTAAGTGCCAGATATGTCATGAAGAATTTCCTTCAGTTTTGTTATTCAATgctcatttaaaaatacaccCATTAGAATGTAGCCAATGtggaaagtatttttataggaaacaaaatttcaaattacacATGAAACGACATTTAGGAATTAAACCATTTCCATGTACTGTTTGTGACAAAgcatttttaacaaaacaaaaattagatGAACATACTAATGGTCATACTGGAAATGCACCAGTTAAATGTAATCTTTGCAATGAAACGTTTCgtagatattcaaatttaacacAGCACAAAAATAGACatcatttgaatataaagaaaaaattaaaagattacatATGTCATTGTGGTGAGGTttttcatacaaaaaaaaagttagcTTGGCATAAAGAAACACATGATGAAAAACCTAAAGCATGTACATATTGTAATGAAAGATTCATTCACATGGCCAGCCTGACTAGACATATGCGTCGAGCTCATAATAAAAGATTCGTTCCAGATGCTCAAAGAGAGAACGAAAATGTTGAATGTCCCGTATGTAAGTGTATTTATTTGCGATCTTCCTTAGCAGTGCATATGCGAGTTCATAATGGCGAAAGACCTTATGAATGTCAAGTTTGCTCTAAAACATTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACTCACGCTGCCCGTAGCACCAAACCTTTTAAGTGTAATCAGTGTAGTGGTGCATTTTACCGACACAGTGATTATACTGCTCATATGAATTCTCACAGAAATGTGCGTCCTTATACTTGTAATTATTGTGGAGCGCAGTTcatacgaaaatataattgtttaaggCACGTAAAAGaacatgaagaaaataaagcatATACATGCGATGTTTGCAACAAAACTTTTCATAGATCATATTATCTAAAAGAACATTTACGAGTACATTCAGGTGCCAGACCATATACATGTCATATATGTGGAAAATCTAGTGGTACAAAATCCAATCATAATAAACATGTAAGAATTCATCATGCACGAGAACCTGTAAATactgaaaattaa
Protein Sequence: MYKQNTSGIMDTTNNGASGGAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASNNASQVHQAQLSSSVPPASPAMQSPQNTPQVAQNTHLSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTAIPNSARVRPVMTMAGETNGRTAIAVPVNNSEPKQILPEILPESEQESEQVLPDINLPVSPPSLNEDNSMQQNESETSTIQIDQEVEESHNSSTSEQHTVQNEYDNIPRSVTITCNVNDTTDDKVESVLPDIDDGESSCVVTTDVQCKSLHYEASEIQGYVHRYEDDDDNNKIITPEVSSMITENEIEKATNEKVPHREEINENEGTSAEMPLEDTVKAPAQREVEQLERLLITIMENEFNNTPQKESNSEDDKKNEGTKKSLSPKRAESVIHETISNNSIEHEHSCESDIKIKLSESSEIDIDNDENKSSCLSYHYKNSLSAPASPIVRKRPHRTYSVRSEFSSNENLNFYPNSFDANTLQDEEDDEDEKNEAEDNFDEADMEIEEIPSPHTPFIKYGENGDNVRSHTPLSASSGISVLRVRKDLSKPCSPASVHSFCHMDTNGLSNDEDSNGAMDESPEKDPIDCSQVEQDVKTDHLELSICENEKKMEGNSAYQSGITEHISSFSTIHSQHSQQSISMVDSYNMPNKSNHINLSESNDVASSSDSKNFHSSKSIIQKQSVELLSLNEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSGTSQQSMASSEGGVGVDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESDGSDNEVAGPLLDSRSLATHFTSSLFLDRDRKTPTKRMFKCYHCPEVFDCPKERRVHSTTAHKEAGPSSSRESTDQPEVKDIKLLDGRMNAFEDIFVPGLHVQQVYHQQPMLHQLQPPQSSDVITKVESDQKVETLVIPSNIEVICTVCNQRFSSEKSLQLHHRRVHVTEPTKRIRESTKCQICHEEFPSVLLFNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNKRFVPDAQRENENVECPVCKCIYLRSSLAVHMRVHNGERPYECQVCSKTFSTKWNLQLHKWTHAARSTKPFKCNQCSGAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_00215196;
80% Identity: -