Basic Information

Insect: Bombus haemorrhoidalis
Gene Symbol: ZFX
Assembly: GCA_014825975.1
Location: CM026161.1:9844324-9848800[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2 1e+02 3.7 0.1 3 23 24 44 23 44 0.94

2 15 2.9 2.6e+02 2.5 3.4 1 23 892 915 892 915 0.80

3 15 0.00046 0.041 14.4 2.1 3 23 1000 1021 998 1021 0.96

4 15 0.013 1.1 9.9 0.5 2 23 1034 1055 1033 1055 0.97

5 15 1.4e-05 0.0013 19.2 3.1 2 23 1058 1079 1057 1079 0.97

6 15 0.012 1 10.0 0.3 1 23 1085 1107 1085 1107 0.95

7 15 2.3e-05 0.0021 18.5 4.5 2 23 1114 1135 1113 1136 0.95

8 15 0.1 9.1 7.0 3.7 5 23 1149 1167 1148 1167 0.97

9 15 2e-05 0.0019 18.7 1.5 3 23 1174 1195 1173 1195 0.97

10 15 0.017 1.5 9.5 0.3 2 23 1211 1231 1210 1231 0.97

11 15 6.2e-05 0.0056 17.2 0.7 1 20 1237 1256 1237 1259 0.92

12 15 0.00032 0.029 14.9 2.8 1 23 1267 1289 1267 1289 0.99

13 15 0.0022 0.19 12.3 3.2 1 23 1295 1317 1295 1317 0.97

14 15 3.9e-06 0.00035 20.9 3.9 1 23 1323 1345 1323 1345 0.99

15 15 0.0013 0.12 12.9 6.3 1 23 1351 1373 1351 1374 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2	1e+02	3.7	0.1	3	23	24	44	23	44	0.94
2	15	2.9	2.6e+02	2.5	3.4	1	23	892	915	892	915	0.80
3	15	0.00046	0.041	14.4	2.1	3	23	1000	1021	998	1021	0.96
4	15	0.013	1.1	9.9	0.5	2	23	1034	1055	1033	1055	0.97
5	15	1.4e-05	0.0013	19.2	3.1	2	23	1058	1079	1057	1079	0.97
6	15	0.012	1	10.0	0.3	1	23	1085	1107	1085	1107	0.95
7	15	2.3e-05	0.0021	18.5	4.5	2	23	1114	1135	1113	1136	0.95
8	15	0.1	9.1	7.0	3.7	5	23	1149	1167	1148	1167	0.97
9	15	2e-05	0.0019	18.7	1.5	3	23	1174	1195	1173	1195	0.97
10	15	0.017	1.5	9.5	0.3	2	23	1211	1231	1210	1231	0.97
11	15	6.2e-05	0.0056	17.2	0.7	1	20	1237	1256	1237	1259	0.92
12	15	0.00032	0.029	14.9	2.8	1	23	1267	1289	1267	1289	0.99
13	15	0.0022	0.19	12.3	3.2	1	23	1295	1317	1295	1317	0.97
14	15	3.9e-06	0.00035	20.9	3.9	1	23	1323	1345	1323	1345	0.99
15	15	0.0013	0.12	12.9	6.3	1	23	1351	1373	1351	1374	0.96

Sequence Information

Coding Sequence: ATGTATAAAGAAAATACCTCAGACATAATGGATGCAGTAAGCAATGGAGCTTCAGGAAGTGCAGTGGCTTGTCCAGTCTGTACCCTCTATCTACGGGAGGGTATCAGCTTACAAAGACATTTGGATACTCATCCAAAAGAACAAGTCATTGAAGCTCTTATTAAAGCTAGTACCAATTCCTCAAATGTGCAACAGACACAATTATCATCATCAGCACCTGCAGCATCTCCAGCTATACAATCATCCCAAAATACACCTCAAGTTGCACAGAATACTCATCTATCGGCTCAATCTCCATATCCTATAGGACCTATTTTCGAATGTCCACCTATCGGTACTGTGATGCCACCTCAGTTTGCTTCATTTAGTTATCAACAGTTTGTAAATAATGGCACTATGATGATACCACAATATGCAATGGCTCCACAAGCTAATCAAATGATGCAAATGCTGTATAATCCATATGGTATGTATCAGCAGCAACAAATACCAACTGTTCAAATGATTTCGCCAGTCACAGCCATACCAAACACCACTAGAGTCAGGCCAGTGGTAACTATGGCTGGTGAAACAACTGGTAGGACTGCCATTGCTGTACCTGTAAATAATTCCGAGCCAAAACAAATTTTACCTGAGATTTTACCTGAATCAGAGCAAGAGTCTGAACAAATGTTATCAGATATCAACCTTCCAGTTTCTCCTCCATCATTAAACGAAGATAATTCTATGCAGCAAAATGAAAGTGAAACTAGTACAATTCAAATAGAGCAAGGAGAGGAGCCCCTTGGTTCAAGTACAGATCAGCATACTGTGCAAGATGAATACGATAGCATTCCAAGATCATTGGCAATTACTTGTAATGTCAATGTCACTACAGATGATAAAGTTGAGAGTGTATTGCCGGATATCGATAATGGGGAATCGTCGTGTGTTGTTACTACAAACGTGCAGTGTAAGTCTATTCATTATGAATCGTCAGAAATGCAGGAGTATGTACACAGATATGAAGATGATGATGATAATAATAAAGTTATTATGCCTGAAGTATCACCAATGGTAACAGAAAATGAGACAGAAAATACAACTAATGAAAAAGTTCCTCACAGAGAAGAAATAAGCAAAAATGAAGGTACCTCAGCAGAAATGCCTGTAGAAGATACAGTAAAAGCACCAGCTCAGCCTGAAGTAGAACAATTAGAACGTCTTTTAATCACTATTATGGAAAATGAATTTAATAATACTCCACAGGGAGAATCCAATTTTGAAGATGATAAAAAGAAGAGTAAAGATTCAAAGAAAAATACTTCTCCTGAAAGGGCTGAAAGTGTAATACATGAAATAACTAGTAATAATCCCATTGAATATGAAAACAGTTGTAAATCTGATGTAAAAGTAAAAGTTAATCAAAGCTCGGAAATTAGTATAGGTAATGATGAAAATAAAAGTTCTTGTCTTTTATACAATTATAAAAACAGTTTGTCTGCACCTCCATCACCTATTGTACAAAGAAGACCCCATAGAACCTATTCTGTTCATTCAGATTTTAGTTCAAATGAACATCTTAATTTTTATCCAATTGGTTTTGATGCAAGCACATTGCATGATGAGGAAGATGATGAAGATGAAAAAAATGAAACAGAAGATAATTTTGATGAGGCAGATATGGAAATAGAGGAAATACCTAGCCCACATACTCCTTTCATTAAATATGATGAAAATGCAGACAATGTTAGATCTCATACTCCATTATCTGCAAGTAGTGGTATTTCTGTATTAAGAGTTAGAAAGGATCTTAGTAAACCATGTTCACCTGCTTCTGTCCATTCATTTTGTCATATGGATGCTAATGGTATAAGCCATGATGAAGAAAGTAATGTAGCAATGGATGAATCACCAGAAAAAGATCCTATTGATTGTTCTTTAGTTGAACAAGATGTGAAAGCTGATCAGTCAGAACTTTCCTTATGCAAAAATGAGAAAAAAGTGGAAGGAGATTCTGCATATCAATCTGGAATTAGTGATCATATGAGTTCGTTTTCTACAATTCATTCACAACATTCTCAGCAATCAACGTTAATGGATGAATCATATAACATGCCAAGTAAAAGTAATAACCATGTAAATTTATCAGAATCTAGTGATGTCGCAAGTAGTTCTGACTCAAAAAGTTTTCATTCATCTAAATCAATTATACAAAAACAATCTGTGGAACTCCTTAGTTTAAACGAAGATGCCCATGCAGGTCCAATGAATGTATTTGAATTTGATGGGCTTCAAATCTTAGTTCCTAGTACATTCATAAGTGATTCTTCACAAAAAGCAGTTAGTGGAACCAGCCAACAATCTATGGCAAGTAGTGAAGGTGGAATAGGTATAGATGAAGAAGTTAAAAGCATTAATATGAGAGCTGATGAAACTATGCCACCCAGAGGTGAACTATCAGAACAAGAAAGCAATGGATGTACAGAACAATCAGCTTGGCAGTTATATGCTGGTCAAGAATCATCAAGAATGTCAACATCTTATGATCTAATGGCACGTGAAAGTTGGGAAGAATCTGATGGATCAGACAATGAAATTACAGGCCCATTATTAGATAGCAGATCTTTAGCAACACATTTTACATCAAGTTTATTTTTAGATCGAGATAGAAAAACTCCTACAAAAAGAATGTTCAAATGTTATCATTGCCCTGAAGTATTTGATTGTCCGAAAGAACGCAGAGTACATAGTACCACCGCGCACAAAGAAGCTGGTCCGAGTAGCAGTAGAGAATCTACAGAACAACCTGAAGTAAAGGATATTAAGTTATTGGATGGCCGTATGAATGTATTTGAAGATATTTTTGTACCAGGTTTACATGTTCAACAAGTTTATCACCAGCAACCACTGTTACATCAACTTCAACCACCACAATCATGTACAGATGTAACTACAAAAGTAGAATCTGATCAAAAAATTGAAACATTAGTAATACCATCAAACATTGAAGTGATCTGCACCCTTTGCAATCAGAGATTTAGTAGTGAAAAATCATTACAGCTACATCATAGAAGAGTACATATTACAGAAACAACAAAACGAATTCGTGAGAGCACCAAGTGTCAGATATGTCACGAAGAATTTCCTTCGGTTCTATTGTACAATGCCCATTTAAAAATACATCCATTAGAATGTAGTCAATGTGGAAAGTATTTTTATAGAAAACAAAATTTCAAATTACACATGAAACGTCATTTAGGAATTAAACCATTTCCGTGTACTGTTTGTGACAAAGCATTTTTAACAAAACAAAAGTTAGATGAACATACCAATGGTCATACCGGGAATGCACCTGTTAAGTGTAATCTTTGCAATGAAACGTTTCGCAGATATTCAAATCTAACACAGCACAAAAATAGACATCATTTGAATATAAAAAAGAAATTGAAAGATTACATATGTCATTGTGGTGAGGTTTTTCATACAAAGAAAAAGCTAGCTTGGCATAAAGAAACACATGATGAAAAACCCAAAGCATGTACATATTGTAATGAAAGATTCATTCACATGGCCAGCCTGACTAGACATATGCGCCGAGCTCATAATAAAAGATTCGTTCCAGATGCTCAAAGAGAGAGCGAAAATGTTGAATGTCCTGTATGTAAGTGTATTTATTTACGATCTTCCTTAGCAGTGCATATGCGAGTACATAATGGTGAAAGACCATATGAATGTCAAGTTTGCTCTAAAGCATTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACTCATGCTGCTCGTAGCACCAAACCTTTTAAGTGTAATCAGTGTAGTGGTGCGTTTTACCGGCACAGTGATTATACTGCTCATATGAATTCTCATAGAAACGTGCGTCCTTATACCTGTAACTATTGCGGAGCGCAGTTCATACGAAAATATAATTGTTTAAGGCATGTAAAAGAACATGAAGAAAACAAAGCATATACATGTGATGTTTGCAACAAAACTTTTCATAGATCATATTATCTGAAAGAACACTTGCGAGTACATTCAGGTGCCAGACCATATACATGTCACATTTGTGGAAAGTCTAGCGGTACGAAATCCAATCATAACAAACATGTCAGAATTCATCATGCACGAGAACCTGTAAATACCGAAAATTAA
Protein Sequence: MYKENTSDIMDAVSNGASGSAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASTNSSNVQQTQLSSSAPAASPAIQSSQNTPQVAQNTHLSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTAIPNTTRVRPVVTMAGETTGRTAIAVPVNNSEPKQILPEILPESEQESEQMLSDINLPVSPPSLNEDNSMQQNESETSTIQIEQGEEPLGSSTDQHTVQDEYDSIPRSLAITCNVNVTTDDKVESVLPDIDNGESSCVVTTNVQCKSIHYESSEMQEYVHRYEDDDDNNKVIMPEVSPMVTENETENTTNEKVPHREEISKNEGTSAEMPVEDTVKAPAQPEVEQLERLLITIMENEFNNTPQGESNFEDDKKKSKDSKKNTSPERAESVIHEITSNNPIEYENSCKSDVKVKVNQSSEISIGNDENKSSCLLYNYKNSLSAPPSPIVQRRPHRTYSVHSDFSSNEHLNFYPIGFDASTLHDEEDDEDEKNETEDNFDEADMEIEEIPSPHTPFIKYDENADNVRSHTPLSASSGISVLRVRKDLSKPCSPASVHSFCHMDANGISHDEESNVAMDESPEKDPIDCSLVEQDVKADQSELSLCKNEKKVEGDSAYQSGISDHMSSFSTIHSQHSQQSTLMDESYNMPSKSNNHVNLSESSDVASSSDSKSFHSSKSIIQKQSVELLSLNEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSGTSQQSMASSEGGIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESDGSDNEITGPLLDSRSLATHFTSSLFLDRDRKTPTKRMFKCYHCPEVFDCPKERRVHSTTAHKEAGPSSSRESTEQPEVKDIKLLDGRMNVFEDIFVPGLHVQQVYHQQPLLHQLQPPQSCTDVTTKVESDQKIETLVIPSNIEVICTLCNQRFSSEKSLQLHHRRVHITETTKRIRESTKCQICHEEFPSVLLYNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNKRFVPDAQRESENVECPVCKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSGAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_00215196;
80% Identity: -