Basic Information

Insect: Bombus polaris
Gene Symbol: ZFX
Assembly: GCA_014737335.1
Location: JACXIO010000150.1:3193910-3198281[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2 1.2e+02 3.7 0.1 3 23 24 44 23 44 0.94

2 15 2.9 3e+02 2.5 3.4 1 23 893 916 893 916 0.80

3 15 0.00047 0.047 14.4 2.1 3 23 1001 1022 999 1022 0.96

4 15 0.013 1.3 9.9 0.5 2 23 1035 1056 1034 1056 0.97

5 15 1.4e-05 0.0015 19.2 3.1 2 23 1059 1080 1058 1080 0.97

6 15 0.012 1.2 10.0 0.3 1 23 1086 1108 1086 1108 0.95

7 15 2.3e-05 0.0024 18.5 4.5 2 23 1115 1136 1114 1137 0.95

8 15 0.1 10 7.0 3.7 5 23 1150 1168 1149 1168 0.97

9 15 2.1e-05 0.0021 18.7 1.5 3 23 1175 1196 1174 1196 0.97

10 15 0.017 1.7 9.5 0.3 2 23 1212 1232 1211 1232 0.97

11 15 6.3e-05 0.0064 17.2 0.7 1 20 1238 1257 1238 1260 0.92

12 15 0.00032 0.033 14.9 2.8 1 23 1268 1290 1268 1290 0.99

13 15 0.0022 0.22 12.3 3.2 1 23 1296 1318 1296 1318 0.97

14 15 4e-06 0.0004 20.9 3.9 1 23 1324 1346 1324 1346 0.99

15 15 0.0014 0.14 12.9 6.3 1 23 1352 1374 1352 1375 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2	1.2e+02	3.7	0.1	3	23	24	44	23	44	0.94
2	15	2.9	3e+02	2.5	3.4	1	23	893	916	893	916	0.80
3	15	0.00047	0.047	14.4	2.1	3	23	1001	1022	999	1022	0.96
4	15	0.013	1.3	9.9	0.5	2	23	1035	1056	1034	1056	0.97
5	15	1.4e-05	0.0015	19.2	3.1	2	23	1059	1080	1058	1080	0.97
6	15	0.012	1.2	10.0	0.3	1	23	1086	1108	1086	1108	0.95
7	15	2.3e-05	0.0024	18.5	4.5	2	23	1115	1136	1114	1137	0.95
8	15	0.1	10	7.0	3.7	5	23	1150	1168	1149	1168	0.97
9	15	2.1e-05	0.0021	18.7	1.5	3	23	1175	1196	1174	1196	0.97
10	15	0.017	1.7	9.5	0.3	2	23	1212	1232	1211	1232	0.97
11	15	6.3e-05	0.0064	17.2	0.7	1	20	1238	1257	1238	1260	0.92
12	15	0.00032	0.033	14.9	2.8	1	23	1268	1290	1268	1290	0.99
13	15	0.0022	0.22	12.3	3.2	1	23	1296	1318	1296	1318	0.97
14	15	4e-06	0.0004	20.9	3.9	1	23	1324	1346	1324	1346	0.99
15	15	0.0014	0.14	12.9	6.3	1	23	1352	1374	1352	1375	0.96

Sequence Information

Coding Sequence: ATGTATAAAGAAAATACCTCAGACACAATGGATGCAGTAAGCAATGGAGCTTCAGGAAGTGCAGTGGCTTGTCCAGTCTGTACCCTCTATCTGCGCGAGGGTATCAGCTTACAAAGACATTTGGATACTCATCCAAAAGAACAAGTCATCGAAGCTCTTATCAAAGCTAGTACCAATTCCTCAAATGTGCAACAGACACAGTTATCATCATCAGCACCTCCAGCATCTCCAGCTATACAATCATCCCAAAATACACCTCAAGTTGCACAGAATACTCATCTATCGGCTCAATCTCCATATCCTATAGGACCTATTTTCGAATGTCCACCTATCGGTACTGTGATGCCACCTCAGTTTGCTTCATTTAGTTATCAACAGTTTGTAAATAATGGCACTATGATGATACCACAATATGCAATGGCTCCACAAGCTAATCAAATGATGCAAATGCTGTATAATCCATATGGTATGTATCAGCAGCAACAAATACCAACTGTTCAAATGATTTCGCCAGTCACAGCCATACCAAACACCACTAGAGTCAGGCCAGTGGTAACTATGGCTGGTGAAACAACTGGTAGAACTGCCATTGCTGTACCTGTAAATAATTCCGAGCCAAAACAAATTTTACCTGAGATTTTACCTGAATCAGAGCAAGAGTCTGAACAAATGTTATCAGATATCAACCTTCCAGTTTCTCCTCCATCATTAAACGAAGATAATTCTATGCAGCAAAATGAAAGTGAAACTAGTACAATTCAAATAGAGCAAGAAGGAGAGGAGCCCCTTGGTTCAAGTACAGATCAGCATACTGTGCAAGATGAATATGATAGCATTCCAAGATCATTGGCAATTACTTGTAATGTCAATGTCACTACAGATGATAAAGTTGAGAGTGTATTGCCGGATATTGATAATGGGGAATCGTCGTGCGTTGTTACTACAAACATGCAGTGTAAGTCTATTCATTATGAATCGTCAGAAATGCAGGAGTATGTACACAGATATGATGACGATGATGATAATAATAAAGTTATTATGTCTGAAGTATCACCAATGGTAACAGAAAATGAGACAGAAAATGCAACTAATGAAAAAGTTCCTCACAGAGAAGAAATAAGCAAAAATGAAGGTACCTCAGCAGAAATGCCTGTAGAAGATACAGTAAAAGCACCAGCTCAGCCTGAAGTAGAACAATTAGAACGTCTTTTAATCACTATTATGGAAAATGAATTTAATAATACTCCACAGAAAGAATCCAATTTTGAAGATGATAAAAAGAAGAGTAAAGATACAAAGAAAAATACTTCTCCTGAAAGGGCTGAAAGTGTAATACATGAAATAACTAGTAATAATCCCATTGAATATGAAAACAGTTGTAAATCTGATGTAAAAGTAAAAGTTAATCAAAGCTTGGAAATTAATATAGATAATGATGAAAATAAAAATTCTTGTCTTTTATACAATTATAAAAACAGTTTGTCTGCACCTCCATCACCTATTGTACAAAGAAGACCCCATAGAACCTATTCTGTTCATTCAGATTTTAGTTCAAATGAACACCTTAATTTTTATCCAATTGGTTTTGATGCAAGCACATTGCACGATGAGGAAGATGATGAAGATGAAAAAAATGAAATAGAAGATAATTTTGATGAGGCAGATATGGAAATAGAGGAAATACCTAGCCCACATACTCCTTTCATTAAATATGATGAACATGCAGACAATGTTAGATCTCATACTCCATTATCTGCAAGCAGTGGTATTTCTGTATTAAGAGTTAGAAAGGATCTTAGTAAACCATGTTCACCTGCTTCTGTCCATTCATTTTGTCATATGGATGCTAATGGTATAAGCCACGATGAAGAAAGTAATGTAGCAATGGACGAATCACCAGAAAAAGATCCTATTGATTGTTCTTTAGTTGAACAAGATGTGAAAGCTGATCAGTCAGAACTTTCCTTATGCAAAAATGAGAAAAAGATGGAAGGAGATTCTGCATATCAATCTGGAATTAGTGACCATATGAGTTCGTTTTCTACAATTCATTCACAACATTCTCAGCAATCAACATTAATGGACGAATCATATAACATGCCAAGTAAAAGTAATAATCATGTAAATTTATCAGAATCTAGTGATGTCGCAAGTAGTTCTGACTCAAAGAGTTTTCATTCATCTAAATCAATTATACAAAAACAATCTGTGGAACTCCTTAGTTTAAATGAAGATGCCCATGCAGGTCCAATGAATGTGTTTGAATTTGATGGGCTTCAAATCTTAGTTCCTAGTACATTCATAAGTGATTCTTCACAAAAAGCAGTTAGTGGAACCAGCCAACAATCTATGGCAAGTAGTGAAGGTGGAATAGGTATAGATGAAGAAGTTAAAAGCATTAATATGAGAGCTGATGAAACTATGCCACCCAGAGGTGAACTATCAGAACAAGAAAGCAATGGATGTACAGAACAATCAGCTTGGCAGTTATATGCTGGGCAAGAATCATCAAGAATGTCAACATCTTATGATCTAATGGCGCGTGAAAGTTGGGAAGAATCTGATGGATCAGACAATGAAATTACAGGCCCATTATTAGATAGCAGATCTTTAGCAACACATTTTACATCAAGTTTATTTTTAGATCGAGATAGAAAAACTCCTACAAAAAGAATGTTCAAATGTTATCATTGCCCTGAAGTATTTGATTGTCCAAAAGAACGCAGAGTACATAGTACCACCGCGCACAAAGAAGCTGGTCCGAGTAGCAGTAGAGAATCTACAGAACAACCTGAAGTAAAGGATATTAAGTTATTGGATGGCCGTATGAATGTATTTGAAGATATTTTTGTACCAGGTTTACATGTTCAACAAGTTTATCACCAGCAACCACTGTTACATCAACTTCAACCACCACAATCATGTACAGATGTAACTACAAAAGTAGAATCTGATCAAAAAATTGAAACACTAGTAATACCATCAAACATTGAAGTGATCTGCACCCTTTGCAATCAGAGATTTAGTAGTGAAAAATCATTACAACTACATCATAGAAGAGTACATATTACAGAAACAACAAAACGAATTCGTGAGAGCACCAAGTGTCAGATATGTCACGAAGAATTTCCTTCGGTTCTATTGTACAATGCCCATTTAAAAATACATCCATTAGAATGTAGTCAATGTGGAAAGTATTTTTATAGAAAACAAAATTTCAAATTACACATGAAACGACATTTAGGAATTAAACCATTTCCATGTACTGTTTGTGACAAAGCATTTTTAACAAAACAGAAGTTAGATGAACATACCAATGGTCATACCGGGAATGCACCTGTTAAGTGTAATCTTTGCAATGAAACATTTCGCAGATATTCAAATCTAACACAGCACAAAAATAGACATCATTTGAATATAAAAAAGAAATTAAAAGATTACATATGTCATTGTGGTGAGGTTTTTCATACAAAGAAAAAGCTAGCTTGGCATAAAGAAACACATGATGAAAAACCCAAAGCATGTACATATTGTAACGAAAGATTCATTCACATGGCCAGCCTGACTAGACATATGCGCCGAGCTCATAATAAAAGATTCGTTCCAGATGCTCAAAGAGAGAGCGAAAATGTTGAATGTCCTGTATGTAAGTGTATTTATTTACGATCTTCCTTAGCAGTGCATATGCGAGTACATAATGGTGAAAGACCATATGAATGTCAAGTTTGCTCTAAAGCATTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACTCACGCTGCTCGTAGCACCAAACCTTTCAAGTGTAATCAGTGTAGTGGCGCGTTTTACCGGCACAGTGATTATACTGCTCATATGAATTCTCATAGAAACGTGCGTCCTTATACCTGTAACTATTGCGGAGCGCAGTTCATACGAAAATATAATTGTTTAAGGCATGTAAAGGAACATGAAGAGAACAAAGCATATACATGTGATGTTTGCAACAAAACTTTTCATAGATCATATTATCTGAAAGAACACTTGCGAGTACATTCAGGTGCCAGACCATATACATGTCATATTTGTGGAAAGTCTAGCGGTACGAAATCCAATCATAACAAACATGTCAGAATTCATCATGCACGAGAACCTGTAAATACCGAAAATTAA
Protein Sequence: MYKENTSDTMDAVSNGASGSAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASTNSSNVQQTQLSSSAPPASPAIQSSQNTPQVAQNTHLSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTAIPNTTRVRPVVTMAGETTGRTAIAVPVNNSEPKQILPEILPESEQESEQMLSDINLPVSPPSLNEDNSMQQNESETSTIQIEQEGEEPLGSSTDQHTVQDEYDSIPRSLAITCNVNVTTDDKVESVLPDIDNGESSCVVTTNMQCKSIHYESSEMQEYVHRYDDDDDNNKVIMSEVSPMVTENETENATNEKVPHREEISKNEGTSAEMPVEDTVKAPAQPEVEQLERLLITIMENEFNNTPQKESNFEDDKKKSKDTKKNTSPERAESVIHEITSNNPIEYENSCKSDVKVKVNQSLEINIDNDENKNSCLLYNYKNSLSAPPSPIVQRRPHRTYSVHSDFSSNEHLNFYPIGFDASTLHDEEDDEDEKNEIEDNFDEADMEIEEIPSPHTPFIKYDEHADNVRSHTPLSASSGISVLRVRKDLSKPCSPASVHSFCHMDANGISHDEESNVAMDESPEKDPIDCSLVEQDVKADQSELSLCKNEKKMEGDSAYQSGISDHMSSFSTIHSQHSQQSTLMDESYNMPSKSNNHVNLSESSDVASSSDSKSFHSSKSIIQKQSVELLSLNEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSGTSQQSMASSEGGIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESDGSDNEITGPLLDSRSLATHFTSSLFLDRDRKTPTKRMFKCYHCPEVFDCPKERRVHSTTAHKEAGPSSSRESTEQPEVKDIKLLDGRMNVFEDIFVPGLHVQQVYHQQPLLHQLQPPQSCTDVTTKVESDQKIETLVIPSNIEVICTLCNQRFSSEKSLQLHHRRVHITETTKRIRESTKCQICHEEFPSVLLYNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNKRFVPDAQRESENVECPVCKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSGAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_00215196;
80% Identity: -