Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02001150.1:1-2240[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.7 8.4e+03 -3.2 0.4 15 35 105 124 99 134 0.53

2 12 1.3 4.1e+03 -2.2 0.0 27 47 210 230 206 236 0.82

3 12 0.44 1.4e+03 -0.7 0.0 26 32 369 375 363 386 0.74

4 12 0.38 1.2e+03 -0.5 0.0 26 48 433 455 428 460 0.82

5 12 0.004 12 5.9 0.0 21 46 456 481 451 487 0.85

6 12 0.00018 0.55 10.2 0.0 21 45 484 508 480 515 0.87

7 12 0.0048 15 5.6 0.1 21 45 512 536 508 541 0.89

8 12 0.15 4.6e+02 0.8 0.0 21 48 564 591 560 596 0.83

9 12 0.00019 0.59 10.1 0.1 21 52 593 624 583 625 0.82

10 12 0.031 97 3.0 0.0 22 45 650 673 647 680 0.84

11 12 0.0018 5.6 7.0 0.2 21 48 677 704 673 708 0.86

12 12 0.00029 0.9 9.5 0.0 21 45 705 729 701 735 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.7	8.4e+03	-3.2	0.4	15	35	105	124	99	134	0.53
2	12	1.3	4.1e+03	-2.2	0.0	27	47	210	230	206	236	0.82
3	12	0.44	1.4e+03	-0.7	0.0	26	32	369	375	363	386	0.74
4	12	0.38	1.2e+03	-0.5	0.0	26	48	433	455	428	460	0.82
5	12	0.004	12	5.9	0.0	21	46	456	481	451	487	0.85
6	12	0.00018	0.55	10.2	0.0	21	45	484	508	480	515	0.87
7	12	0.0048	15	5.6	0.1	21	45	512	536	508	541	0.89
8	12	0.15	4.6e+02	0.8	0.0	21	48	564	591	560	596	0.83
9	12	0.00019	0.59	10.1	0.1	21	52	593	624	583	625	0.82
10	12	0.031	97	3.0	0.0	22	45	650	673	647	680	0.84
11	12	0.0018	5.6	7.0	0.2	21	48	677	704	673	708	0.86
12	12	0.00029	0.9	9.5	0.0	21	45	705	729	701	735	0.91

Sequence Information

Coding Sequence: ATGCTGGGCAAGTATGGCGAGGCGAGTTCCGGCTCGATGAAAAACCTGGAAAATGGACTGCGGGACCGCGTGCTCTACCATCAGAATATGCTGAGCATGAACCTGACGACCGAATTTTACCACACTCCATTCCTTACGGCCGGCAGTGGTAGCAACGTTGAAACAGCTGCAATCGTAGTAGGCGCTCCCGCGCTGGCACAGTCGCAAAAGATGCTCAACAGTCTCGCATCCCCCTCTGGACTAGCCTCCTCCTCCTCTTCCAGCACCACGCAACAGCACGCCACTAATGGGGCAGCGCCGTCACAGACAGTCCCAAACAGTGTGTCCGCAGCGCAGCAGTATCAGTGTCAACTCTGCCAGAAGTGTTTCATTTCGAGCGCGTTACTGGTGCAGCATATGAAAACGCACGACAATAATGGGTTTATTGCAGGGCGTGAGACCGCCGGCAGCTACGGCCAACAGCAGCAGCAGCAGCAATCGGTATCGTCGGCCTCTTCCCCCGTGACGGCAGTGGCATCGAGCAGCAAAACTAGTCCGCCAGTGGCAACGCAGCACATCATCAAGAGCGAGTACATCGGTGGAACCGTAACGAACCAGTATGCGTACGGTATGGCCAAGCAGTTCGAGTGTCACATCTGCCACAAGTCCTTCATGACGATGGTGAACCTGAACCTGCACATGAAGATACACGAAAGTGCAATAAAGCCGCTCGTAGCGACTCACATGTACGCGGGCCAGGCAGGCCTTGCCGGCAACTTGATTGCCGGATCGGCCGCGGGCTACCATCACGGCGGGCAGCATCACAGTCAGCTGTCGCAGCATCTTGCGGTTCAAAGTGTCAGCGGCAGTGCGGACGGGCTGTGCCAGATATGCCACAAAACGTTCAGCACGGCGGACCAGTTCGCGGCGCACATGAAGATCCACGAGAATGAGTTTAAAAATCGTGCGCTTTATCATTCCGGTAGTGCGAACGATGGTGGCGAGGGAGCGCCGGCACCCACCAGTAATGGGGCTGGTGTCGGAGACCATTTCTACACCGCGTCACAGCCGCCACACCACCATCTGGGCCATGCACCGCCGCATCTCGATGCTAGCAAGGGCCATCGGTGCCCGATTTGTCACAAAATGTCCAACAACATCATCGAGCACATTAAACAGCACGAGGGTCAGCTGCAGGGCACGTCCGATGGGTCGGGTGCGGGGTATCATCCTACGAACGATGATTCCCAATCGTCGCTGGAAGAAGACAGCGACGGTGGTGGTGGCGCTGGCGGGGACGAGAGCCTGCGAAAGCACGAATGCTTGATATGCCACAAAAAGTTCTCCAGCTCGGGCAACCTGGCGATACACATACGGGTGCATTCGGGCGAAAAGCCGTTCCGGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATCTGGCGACGCACATGAAGACGCACACGGGCGAAAAGCCGTACGCGTGCACCATCTGCGGCAAGAACTTTAGCCAGTCGAACAACCTGAAGACGCACATCCGGACGCACACGGGCGAAAAGCCGTACGCCTGTACGATCTGCGGCAAGCGCTTCAACCAGAAGAACAACCTGACCACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGGGTGCAGTTCATGCATCCGATCGATCTGGCGACCCACATGAAGTTCCACAACGACGAAAAACCCTACATCTGCTCGGTGTGCAACAAGGTCTACCTGAACCTGGACGAGCTGACCGAGCACATGAAGAAGACGCACAACCAGGTGAAGCCGTACCGGTGCCACATCTGCGACAAAACCTTTACCCAATCCAACAACCTGAAGACCCACATCAAGACGCACATCTTTCAGGATCCGTACAAGTGTCAGGTGTGCTCGCGCTCCTTCCAGAAGGAGGATGACTTCTCGCAGCACATGTTGGTCCACACGGCCGATAAGCCGTACGAGTGTACGTACTGCGGCAAGCGGTTCATTCAGTCGAACAACCTGAAAACGCACGTGCGCACGCACACGGGCGAAAAGCCGTACCGGTGCACGATCTGCGCGAAGCACTTTAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACGGGGGAGAAACCGTTCGAGTGTACCATCTGCGACAAGCGGTTCAATCAGTCGAACAATTTGAACAAACACATTAAAACACACGGTCAGGAGAAGGATCAGCAGCAGCAGCAGTCCCAGCAACAGCAGCC
Protein Sequence: MLGKYGEASSGSMKNLENGLRDRVLYHQNMLSMNLTTEFYHTPFLTAGSGSNVETAAIVVGAPALAQSQKMLNSLASPSGLASSSSSSTTQQHATNGAAPSQTVPNSVSAAQQYQCQLCQKCFISSALLVQHMKTHDNNGFIAGRETAGSYGQQQQQQQSVSSASSPVTAVASSSKTSPPVATQHIIKSEYIGGTVTNQYAYGMAKQFECHICHKSFMTMVNLNLHMKIHESAIKPLVATHMYAGQAGLAGNLIAGSAAGYHHGGQHHSQLSQHLAVQSVSGSADGLCQICHKTFSTADQFAAHMKIHENEFKNRALYHSGSANDGGEGAPAPTSNGAGVGDHFYTASQPPHHHLGHAPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLQGTSDGSGAGYHPTNDDSQSSLEEDSDGGGGAGGDESLRKHECLICHKKFSSSGNLAIHIRVHSGEKPFRCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPIDLATHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQVCSRSFQKEDDFSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQSQQQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101361;
90% Identity: iTF_00104528; iTF_00107119; iTF_00101361; iTF_00101095; iTF_00093596; iTF_00093863; iTF_00102751; iTF_00102498;
80% Identity: iTF_00104528;