Basic Information

Insect: Anopheles gambiae
Gene Symbol: -
Assembly: GCF_000005575.2
Location: NT:46274131-46276598[+]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3.9 9.7e+03 -3.7 0.5 9 26 78 95 77 97 0.79

2 13 2.9 7.2e+03 -3.3 0.4 15 35 105 124 99 134 0.53

3 13 1.8 4.6e+03 -2.7 0.1 27 46 211 230 208 236 0.84

4 13 0.47 1.2e+03 -0.8 0.0 26 32 370 376 364 387 0.74

5 13 1.3 3.2e+03 -2.2 0.0 27 44 437 454 433 459 0.87

6 13 0.0038 9.6 5.9 0.0 21 46 459 484 453 490 0.85

7 13 0.00029 0.72 9.5 0.0 21 44 487 510 483 514 0.91

8 13 0.0051 13 5.5 0.1 21 45 515 539 511 544 0.89

9 13 0.16 4e+02 0.7 0.0 21 48 567 594 563 599 0.83

10 13 0.00021 0.53 9.9 0.1 22 52 597 627 587 628 0.82

11 13 0.033 83 2.9 0.0 22 45 653 676 650 683 0.84

12 13 0.0018 4.5 7.0 0.2 21 48 680 707 675 711 0.86

13 13 0.00031 0.76 9.4 0.0 21 45 708 732 704 738 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3.9	9.7e+03	-3.7	0.5	9	26	78	95	77	97	0.79
2	13	2.9	7.2e+03	-3.3	0.4	15	35	105	124	99	134	0.53
3	13	1.8	4.6e+03	-2.7	0.1	27	46	211	230	208	236	0.84
4	13	0.47	1.2e+03	-0.8	0.0	26	32	370	376	364	387	0.74
5	13	1.3	3.2e+03	-2.2	0.0	27	44	437	454	433	459	0.87
6	13	0.0038	9.6	5.9	0.0	21	46	459	484	453	490	0.85
7	13	0.00029	0.72	9.5	0.0	21	44	487	510	483	514	0.91
8	13	0.0051	13	5.5	0.1	21	45	515	539	511	544	0.89
9	13	0.16	4e+02	0.7	0.0	21	48	567	594	563	599	0.83
10	13	0.00021	0.53	9.9	0.1	22	52	597	627	587	628	0.82
11	13	0.033	83	2.9	0.0	22	45	653	676	650	683	0.84
12	13	0.0018	4.5	7.0	0.2	21	48	680	707	675	711	0.86
13	13	0.00031	0.76	9.4	0.0	21	45	708	732	704	738	0.91

Sequence Information

Coding Sequence: ATGCTGGGCAAGTATGGCGAGGCGAGTTCCGGCTCGATGAAAAACCTGGAAAATGGACTGCGGGACCGCGTGCTCTACCATCAGAATATGCTGAGCATGAACCTGACGACCGAGTTTTACCACACTCCATTCCTTACGGCCGGCAGTGGTAGTAACGTTGAAACAGCTGCAATCGTAGTAGGCGCTCCCGCGCTGGCACAGTCGCAAAAGATGCTCAACAGTCTCGCATCCCCCTCTGGATtagcctcctcctcctcttccagCACCTCGCAACAGCACGCCACTAATGGAGCAGCGCCGTCACAGACAGTCCCAAACAGTGTATCCGCAGCGCAACAGTATCAGTGTCAACTCTGCCAGAAGTGTTTCATCTCGAGCGCGTTACTGGTGCAGCATATGAAAACGCACGACAATAATGGGTTTATTGCGGGGCGTGAGACCGCCGGCAGCTAcgggcaacagcagcagcagcagcagcaatcggtATCGTCGGCCTCTTCCCCCGTGACGGCAGTGGCATCGAGCAGCAAAACTAGTCCGCCAGTCGCAACGCAGCACATCATCAAGAGCGAGTACATCGGTGGAACCGTAACGAACCAGTATGCATACGGTATGGCCAAGCAGTTCGAGTGTCACATCTGCCACAAGTCCTTCATGACGATGGTGAACCTGAACCTGCACATGAAGATACACGAAAGTGCAATAAAGCCGCTCGCAGCGACTCACATGTACGCGGGCCAGGCAGGCCTTGCCGGCAACTTGATTGCTGGATCGACCGCGGGCTACCATCACGGCGGGCAGCATCACAGTCAGCTGTCGCAGCATCTCGCGGTTCAAAGCGCCAGCGGCAGTGCGGACGGGCTGTGCCAGATATGCCACAAAACGTTCAGCACGGCGGACCAGTTCGCGGCGCACATGAAGATCCACGAGAATGAGTTTAAAAATCGTGCGCTTTATCATTCCGGTAGTGCGAACGATGGTGGCGAGGGAGCACCGGCACCCACCAGTAATGGGGCTGGTGTCGGAGACCATTTCTACACCGCGTCACAGCCGCCACACCACCATCTGGGTCATGCACCGCCGCATCTCGATGCTAGCAAGGGCCATCGCTGCCCGATTTGTCACAAAATGTCCAACAACATCATCGAGCACATCAAACAGCACGAGGGTCAGCTGCAGGGCACGTCCGATGGGTCGGGTGCGGGGTATCATCCTACGAACGATGATTCCCAATCGTCGCTGGAAGAAGACagcgacggtggtggtggtggtggcgctggcGGGGACGAGAACCTGCGAAAGCACGAGTGTTTGATATGCCACAAAAAGTTCTCCAGCTCGGGCAACCTGGCGATACACATACGGGAGCATTCGGGTGAAAAACCGTTCCGGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATCTGGCGACGCACATGAAGACGCACACGGGCGAAAAGCCGTACGCGTGCACCATCTGCGGCAAGAACTTTAGCCAGTCGAACAACCTGAAGACGCACATCCGGACACACACGGGCGAAAAGCCGTACGCGTGTACGATCTGCGGCAAGCGCTTCAACCAGAAGAACAACCTGACCACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGGGTGCAGTTCATGCATCCGATCGATCTGGCGACCCACATGAAGTTCCACAACGACGAAAAACCCTACATCTGCTCGGTGTGCAACAAGGTCTACCTGAACCTGGACGAGCTGACCGAACACATGAAGAAGACGCACAACCAGGTAAAGCCGTACCGGTGCCACATCTGCGACAAAACCTTTACCCAATCGAACAACCTGAAGACCCACATCAAGACGCACATCTTTCAGGATCCGTACAAGTGTCAGGTGTGCTCGCGCTCCTTCCAGAAGGAGGATGACTTCTCGCAGCACATGCTGGTCCACACGGCCGACAAGCCGTACGAGTGTACGTACTGCGGCAAGCGGTTCATTCAGTCGAACAACCTGAAAACGCACGTGCGCACGCACACGGGCGAAAAGCCGTACCGGTGCACGATTTGCGCGAAGCACTTTAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACGGGGGAGAAACCGTTCGAGTGTACCATCTGCGACAAGCGCTTTAATCAGTCGAACAATTTGaacaaacacattaaaacacaCGGCCAGGAGAaggatcagcagcagcagcagTTGACGAGAATTGGCAGCTTAAGACGGTTTTACACTGTGTTTAAATCATACATCACCACTCCTCCCGTCCGTGTGACTCATTCTCTCTGGAGGGCGGGCATTATGTCTGTATGTAAGGCGCAACGGTTGTGCCAATAG
Protein Sequence: MLGKYGEASSGSMKNLENGLRDRVLYHQNMLSMNLTTEFYHTPFLTAGSGSNVETAAIVVGAPALAQSQKMLNSLASPSGLASSSSSSTSQQHATNGAAPSQTVPNSVSAAQQYQCQLCQKCFISSALLVQHMKTHDNNGFIAGRETAGSYGQQQQQQQQSVSSASSPVTAVASSSKTSPPVATQHIIKSEYIGGTVTNQYAYGMAKQFECHICHKSFMTMVNLNLHMKIHESAIKPLAATHMYAGQAGLAGNLIAGSTAGYHHGGQHHSQLSQHLAVQSASGSADGLCQICHKTFSTADQFAAHMKIHENEFKNRALYHSGSANDGGEGAPAPTSNGAGVGDHFYTASQPPHHHLGHAPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLQGTSDGSGAGYHPTNDDSQSSLEEDSDGGGGGGAGGDENLRKHECLICHKKFSSSGNLAIHIREHSGEKPFRCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPIDLATHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQVCSRSFQKEDDFSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQLTRIGSLRRFYTVFKSYITTPPVRVTHSLWRAGIMSVCKAQRLCQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101361;
90% Identity: iTF_00104825;
80% Identity: iTF_00102498;