Agam007895.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles gambiae
Gene Symbol
-
Assembly
GCF_000005575.2
Location
NT:46274131-46276598[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.7e-06 8.8e-05 22.3 2.5 1 23 114 136 114 136 0.99
2 15 5.4e-06 0.00027 20.7 3.8 1 23 209 231 209 231 0.98
3 15 1.7e-06 8.6e-05 22.3 1.2 3 23 289 309 288 309 0.98
4 15 0.54 27 5.0 0.7 1 10 369 378 369 388 0.79
5 15 2.5e-06 0.00013 21.8 1.9 1 23 435 457 435 457 0.97
6 15 7.3e-08 3.7e-06 26.6 0.6 1 23 463 485 463 485 0.99
7 15 9.6e-09 4.9e-07 29.4 1.0 1 23 491 513 491 513 0.98
8 15 6.6e-09 3.4e-07 29.9 1.8 1 23 519 541 519 541 0.98
9 15 0.0033 0.17 11.9 0.2 2 23 544 565 543 565 0.95
10 15 0.00026 0.013 15.4 0.4 1 23 571 594 571 594 0.97
11 15 2.1e-08 1.1e-06 28.3 4.7 1 23 600 622 600 622 0.99
12 15 9.8e-05 0.005 16.7 1.2 1 23 628 650 628 650 0.99
13 15 2.9e-08 1.5e-06 27.8 1.8 1 23 656 678 656 678 0.99
14 15 1e-06 5.2e-05 23.0 3.6 1 23 684 706 684 706 0.99
15 15 2.7e-08 1.4e-06 27.9 2.0 1 23 712 734 712 734 0.98

Sequence Information

Coding Sequence
ATGCTGGGCAAGTATGGCGAGGCGAGTTCCGGCTCGATGAAAAACCTGGAAAATGGACTGCGGGACCGCGTGCTCTACCATCAGAATATGCTGAGCATGAACCTGACGACCGAGTTTTACCACACTCCATTCCTTACGGCCGGCAGTGGTAGTAACGTTGAAACAGCTGCAATCGTAGTAGGCGCTCCCGCGCTGGCACAGTCGCAAAAGATGCTCAACAGTCTCGCATCCCCCTCTGGATtagcctcctcctcctcttccagCACCTCGCAACAGCACGCCACTAATGGAGCAGCGCCGTCACAGACAGTCCCAAACAGTGTATCCGCAGCGCAACAGTATCAGTGTCAACTCTGCCAGAAGTGTTTCATCTCGAGCGCGTTACTGGTGCAGCATATGAAAACGCACGACAATAATGGGTTTATTGCGGGGCGTGAGACCGCCGGCAGCTAcgggcaacagcagcagcagcagcagcaatcggtATCGTCGGCCTCTTCCCCCGTGACGGCAGTGGCATCGAGCAGCAAAACTAGTCCGCCAGTCGCAACGCAGCACATCATCAAGAGCGAGTACATCGGTGGAACCGTAACGAACCAGTATGCATACGGTATGGCCAAGCAGTTCGAGTGTCACATCTGCCACAAGTCCTTCATGACGATGGTGAACCTGAACCTGCACATGAAGATACACGAAAGTGCAATAAAGCCGCTCGCAGCGACTCACATGTACGCGGGCCAGGCAGGCCTTGCCGGCAACTTGATTGCTGGATCGACCGCGGGCTACCATCACGGCGGGCAGCATCACAGTCAGCTGTCGCAGCATCTCGCGGTTCAAAGCGCCAGCGGCAGTGCGGACGGGCTGTGCCAGATATGCCACAAAACGTTCAGCACGGCGGACCAGTTCGCGGCGCACATGAAGATCCACGAGAATGAGTTTAAAAATCGTGCGCTTTATCATTCCGGTAGTGCGAACGATGGTGGCGAGGGAGCACCGGCACCCACCAGTAATGGGGCTGGTGTCGGAGACCATTTCTACACCGCGTCACAGCCGCCACACCACCATCTGGGTCATGCACCGCCGCATCTCGATGCTAGCAAGGGCCATCGCTGCCCGATTTGTCACAAAATGTCCAACAACATCATCGAGCACATCAAACAGCACGAGGGTCAGCTGCAGGGCACGTCCGATGGGTCGGGTGCGGGGTATCATCCTACGAACGATGATTCCCAATCGTCGCTGGAAGAAGACagcgacggtggtggtggtggtggcgctggcGGGGACGAGAACCTGCGAAAGCACGAGTGTTTGATATGCCACAAAAAGTTCTCCAGCTCGGGCAACCTGGCGATACACATACGGGAGCATTCGGGTGAAAAACCGTTCCGGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATCTGGCGACGCACATGAAGACGCACACGGGCGAAAAGCCGTACGCGTGCACCATCTGCGGCAAGAACTTTAGCCAGTCGAACAACCTGAAGACGCACATCCGGACACACACGGGCGAAAAGCCGTACGCGTGTACGATCTGCGGCAAGCGCTTCAACCAGAAGAACAACCTGACCACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGGGTGCAGTTCATGCATCCGATCGATCTGGCGACCCACATGAAGTTCCACAACGACGAAAAACCCTACATCTGCTCGGTGTGCAACAAGGTCTACCTGAACCTGGACGAGCTGACCGAACACATGAAGAAGACGCACAACCAGGTAAAGCCGTACCGGTGCCACATCTGCGACAAAACCTTTACCCAATCGAACAACCTGAAGACCCACATCAAGACGCACATCTTTCAGGATCCGTACAAGTGTCAGGTGTGCTCGCGCTCCTTCCAGAAGGAGGATGACTTCTCGCAGCACATGCTGGTCCACACGGCCGACAAGCCGTACGAGTGTACGTACTGCGGCAAGCGGTTCATTCAGTCGAACAACCTGAAAACGCACGTGCGCACGCACACGGGCGAAAAGCCGTACCGGTGCACGATTTGCGCGAAGCACTTTAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACGGGGGAGAAACCGTTCGAGTGTACCATCTGCGACAAGCGCTTTAATCAGTCGAACAATTTGaacaaacacattaaaacacaCGGCCAGGAGAaggatcagcagcagcagcagTTGACGAGAATTGGCAGCTTAAGACGGTTTTACACTGTGTTTAAATCATACATCACCACTCCTCCCGTCCGTGTGACTCATTCTCTCTGGAGGGCGGGCATTATGTCTGTATGTAAGGCGCAACGGTTGTGCCAATAG
Protein Sequence
MLGKYGEASSGSMKNLENGLRDRVLYHQNMLSMNLTTEFYHTPFLTAGSGSNVETAAIVVGAPALAQSQKMLNSLASPSGLASSSSSSTSQQHATNGAAPSQTVPNSVSAAQQYQCQLCQKCFISSALLVQHMKTHDNNGFIAGRETAGSYGQQQQQQQQSVSSASSPVTAVASSSKTSPPVATQHIIKSEYIGGTVTNQYAYGMAKQFECHICHKSFMTMVNLNLHMKIHESAIKPLAATHMYAGQAGLAGNLIAGSTAGYHHGGQHHSQLSQHLAVQSASGSADGLCQICHKTFSTADQFAAHMKIHENEFKNRALYHSGSANDGGEGAPAPTSNGAGVGDHFYTASQPPHHHLGHAPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLQGTSDGSGAGYHPTNDDSQSSLEEDSDGGGGGGAGGDENLRKHECLICHKKFSSSGNLAIHIREHSGEKPFRCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPIDLATHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQVCSRSFQKEDDFSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQLTRIGSLRRFYTVFKSYITTPPVRVTHSLWRAGIMSVCKAQRLCQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101361;
90% Identity
iTF_00104825;
80% Identity
iTF_00102751;