Aara002620.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles arabiensis
Gene Symbol
-
Assembly
GCA_016920715.1
Location
NC:108863991-108868897[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.8e-06 8.4e-05 22.3 2.5 1 23 114 136 114 136 0.99
2 15 5.5e-06 0.00026 20.7 3.8 1 23 210 232 210 232 0.98
3 15 1.7e-06 8.2e-05 22.3 1.2 3 23 290 310 289 310 0.98
4 15 0.55 26 5.0 0.7 1 10 370 379 370 389 0.79
5 15 9.9e-07 4.7e-05 23.1 1.7 1 23 436 458 436 458 0.97
6 15 7.4e-08 3.6e-06 26.6 0.6 1 23 464 486 464 486 0.99
7 15 9.7e-09 4.7e-07 29.4 1.0 1 23 492 514 492 514 0.98
8 15 6.7e-09 3.2e-07 29.9 1.8 1 23 520 542 520 542 0.98
9 15 0.0033 0.16 12.0 0.2 2 23 545 566 544 566 0.95
10 15 0.00026 0.013 15.4 0.4 1 23 572 595 572 595 0.97
11 15 2.2e-08 1e-06 28.3 4.7 1 23 601 623 601 623 0.99
12 15 9.9e-05 0.0048 16.8 1.2 1 23 629 651 629 651 0.99
13 15 3e-08 1.4e-06 27.9 1.8 1 23 657 679 657 679 0.99
14 15 1e-06 4.9e-05 23.0 3.6 1 23 685 707 685 707 0.99
15 15 2.7e-08 1.3e-06 28.0 2.0 1 23 713 735 713 735 0.98

Sequence Information

Coding Sequence
ATGCTGGGCAAGTATGGCGAGGCGAGTTCCGGCTCGATGAAAAACCTGGAAAATGGACTGCGCGACCGGGTGCTTTACCATCAGAATATGCTGAGCATGAACCTGACAACCGAGTTTTACCACACTCCATTCCTTACGGCCGGCAGTGGTAGCAACGTTGAAACAGCTGCAATCGTAGTAGGCGCTCCCGCGCTGGCACAGTCGCAAAAGATGCTCAACAGTCTCGCATCCCCCTCTGGATtagcctcctcctcctcttccagCACCTCGCAACAGCACGCCACTAATGGGGCAGCGCCGTCACAGACAGTCCCAAACAGTGTGTCCGCAGCGCAGCAGTATCAGTGTCAACTCTGCCAGAAGTGTTTCATCTCGAGCGCGTTACTGGTGCAGCATATGAAAACGCACGACAATAATGGGTTTATTGCGGGGCGTGAGACCGCCGGCAGCTAcggccaacagcagcagcagcagcagcagcaatcggtATCGTCGGCCTCTTCCCCCGTGACGGCAGTGGCATCGAGCAGCAAAACTAGTCCGCCAGTCGCAACGCAGCACATCATCAAGAGCGAGTACATCGGTGGAACCGTAACGAACCAGTATGCGTACGGTATGGCCAAGCAGTTCGAGTGTCACATCTGCCACAAGTCCTTCATGACGATGGTGAACCTGAACCTGCACATGAAGATACACGAAAGTGCAATAAAGCCGCTCGCAGCGACTCACATGTACGCGGGCCAGGCAGGCCTTGCCGGCAACTTGATTGCTGGATCGACCGCGGGCTACCATCACGGCGGGCAGCATCACAGTCATCTGTCGCAGCATCTCGCGGTTCAAAGCGCCAGCAGCAGTGCGGACGGGTTGTGCCAGATATGCCACAAAACGTTCAGCACGGCCGACCAGTTTGCGGCGCACATGAAGATCCACGAGAATGAGTTTAAAAATCGAGCGCTATATCATTCCGGTAGTGCGAACGATGGTGGCGAGGGAGCGCCAGCACCCACCAGTAATGGGGCTGGTGTCGGAGACCATTTCTACACCGCGTCACAGCCGCCACACCACCATCTGGGTCATGCACCGCCGCATCTCGATGCTAGCAAGGGCCATCGCTGCCCAATCTGTCACAAAATGTCCAACAACATCATCGAGCACATTAAACAGCACGAGGGTCAGCTGCAGGGCACGTCCGATGGGTCGGGTGCGGGGTATCATCCTATGAACGATGATTCCCAATCGTCGCTGGAAGAAGACAgcgacggtggcggtggtggtggcgctggCGGGGACGAGAGCCTGCGAAAGCACGAGTGCTTGATATGCCACAAAAAGTTCTCCAGCTCGGGCAACCTGGCGATACACATACGGGTGCATTCGGGCGAAAAGCCGTTCCGGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATCTGGCGACGCACATGAAGACGCACACGGGTGAAAAGCCGTACGCGTGCACCATCTGCGGCAAGAACTTTAGCCAGTCGAACAACCTGAAGACGCACATCCGGACGCACACGGGCGAAAAGCCGTACGCGTGTACAATCTGCGGCAAGCGCTTCAACCAGAAGAACAACCTGACCACGCACATGCGCACACACCAGCTGGTGTGCATGGTGTGCGGGGTGCAGTTCATGCATCCGATCGATCTGGCGACCCACATGAAGTTCCACAACGACGAAAAACCCTACATCTGCTCGGTGTGCAACAAGGTCTACCTGAACCTGGACGAGCTGACCGAGCACATGAAGAAGACGCACAACCAGGTAAAGCCGTATCGGTGCCACATCTGCGACAAAACCTTTACCCAATCCAACAACCTGAAGACCCACATCAAGACGCACATCTTTCAGGATCCGTACAAGTGTCAGGTGTGTTCGCGCTCCTTCCAGAAGGAGGATGACTTCTCGCAGCACATGCTGGTCCACACGGCCGACAAGCCGTACGAGTGTACGTACTGCGGCAAGCGGTTCATCCAGTCGAACAACCTGAAAACGCACGTGCGCACGCACACGGGCGAAAAGCCGTACCGGTGCACGATCTGCGCGAAGCACTTTAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACGGGGGAGAAACCGTTCGAGTGTACCATCTGCGACAAGCGCTTTAATCAGTCGAACAATTTGaacaaacacattaaaacacaCGGCCAGGAGaaggatcagcagcagcagcagtcccagcagcagcagcagcagcagaaccaacaacaacaacagcaagtccagcaacaacagcagcagcagcagcaacatgcgAGTTGA
Protein Sequence
MLGKYGEASSGSMKNLENGLRDRVLYHQNMLSMNLTTEFYHTPFLTAGSGSNVETAAIVVGAPALAQSQKMLNSLASPSGLASSSSSSTSQQHATNGAAPSQTVPNSVSAAQQYQCQLCQKCFISSALLVQHMKTHDNNGFIAGRETAGSYGQQQQQQQQQSVSSASSPVTAVASSSKTSPPVATQHIIKSEYIGGTVTNQYAYGMAKQFECHICHKSFMTMVNLNLHMKIHESAIKPLAATHMYAGQAGLAGNLIAGSTAGYHHGGQHHSHLSQHLAVQSASSSADGLCQICHKTFSTADQFAAHMKIHENEFKNRALYHSGSANDGGEGAPAPTSNGAGVGDHFYTASQPPHHHLGHAPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLQGTSDGSGAGYHPMNDDSQSSLEEDSDGGGGGGAGGDESLRKHECLICHKKFSSSGNLAIHIRVHSGEKPFRCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPIDLATHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQVCSRSFQKEDDFSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQSQQQQQQQNQQQQQQVQQQQQQQQQHAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101361;
90% Identity
iTF_00104825;
80% Identity
iTF_00093863;