Basic Information

Insect: Tipula unca
Gene Symbol: -
Assembly: GCA_951394425.1
Location: OX596380.1:235025482-235028946[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0008 0.12 14.3 0.2 2 23 237 258 236 258 0.97

2 16 1.6 2.3e+02 4.0 3.4 1 23 319 339 319 339 0.81

3 16 0.00033 0.05 15.5 0.8 2 23 346 368 346 368 0.97

4 16 0.00022 0.033 16.1 4.4 1 23 380 402 380 402 0.98

5 16 0.00032 0.047 15.6 1.1 1 23 408 430 408 430 0.99

6 16 1.5e-06 0.00023 22.9 1.1 1 23 436 458 436 458 0.98

7 16 0.00081 0.12 14.3 0.6 2 23 499 520 498 520 0.96

8 16 0.0011 0.17 13.9 2.0 2 23 680 701 679 701 0.95

9 16 0.0022 0.32 12.9 0.6 1 23 707 730 707 730 0.93

10 16 0.019 2.8 10.0 0.6 2 23 788 809 787 809 0.96

11 16 0.0001 0.015 17.1 1.3 1 23 928 950 928 950 0.98

12 16 0.0015 0.22 13.5 3.3 1 23 956 978 956 978 0.96

13 16 2.6e-06 0.00039 22.1 0.9 1 23 984 1006 984 1006 0.98

14 16 9.6e-05 0.014 17.2 0.5 1 23 1018 1040 1018 1040 0.98

15 16 6e-06 0.00089 21.0 2.1 1 23 1046 1068 1046 1068 0.98

16 16 6.2e-05 0.0091 17.8 1.7 1 23 1074 1096 1074 1096 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0008	0.12	14.3	0.2	2	23	237	258	236	258	0.97
2	16	1.6	2.3e+02	4.0	3.4	1	23	319	339	319	339	0.81
3	16	0.00033	0.05	15.5	0.8	2	23	346	368	346	368	0.97
4	16	0.00022	0.033	16.1	4.4	1	23	380	402	380	402	0.98
5	16	0.00032	0.047	15.6	1.1	1	23	408	430	408	430	0.99
6	16	1.5e-06	0.00023	22.9	1.1	1	23	436	458	436	458	0.98
7	16	0.00081	0.12	14.3	0.6	2	23	499	520	498	520	0.96
8	16	0.0011	0.17	13.9	2.0	2	23	680	701	679	701	0.95
9	16	0.0022	0.32	12.9	0.6	1	23	707	730	707	730	0.93
10	16	0.019	2.8	10.0	0.6	2	23	788	809	787	809	0.96
11	16	0.0001	0.015	17.1	1.3	1	23	928	950	928	950	0.98
12	16	0.0015	0.22	13.5	3.3	1	23	956	978	956	978	0.96
13	16	2.6e-06	0.00039	22.1	0.9	1	23	984	1006	984	1006	0.98
14	16	9.6e-05	0.014	17.2	0.5	1	23	1018	1040	1018	1040	0.98
15	16	6e-06	0.00089	21.0	2.1	1	23	1046	1068	1046	1068	0.98
16	16	6.2e-05	0.0091	17.8	1.7	1	23	1074	1096	1074	1096	0.97

Sequence Information

Coding Sequence: ATGGAACGATATACATTGGCGATAAAGCAGGAAAATGGATACGAAATCACGGAAAGCGGTATTATCAATGGTATTAATAGCCTCGGTGAGAATATTACAATTGCCCAGTATGAAATTCAGCCGCAACAACAGATTCATCATGGTACGATGATGCTGCAACATCCACAAATTATCATACATCAGCAAAGGGTAccacaacagcaacaacatcatatactacaacaacaacatcatcatATACAACAGATCCAACATATTACACCATCCTCGACCCCAAATCACTTACAGCATCACACAATTCATATCCACAATGAAGAAGAGTCGAACGGGAGTAATtccatattatatacaaataatacacATTCACAGTGTACTACGCCGCATATACAGATACAAATTCATCGGGCAGATGGGAGTAGGCCGAGTTCAGTGCAGCACATACCGGCGGAATTAGTGCAAGTGTCTAGTCCGTTACAAGTACAGTCACCACATTATCATAATAATCAACATCAACAGATTATTATTCATCAGCCAGTAACCACAATAGTAGAAGAGTTACAACCACAGGATCTCGAGATAGCTCATCAGGAGGAGATTATTACGATACCAGCACAGATAATACAGAAAGTAGAATGTCCAGCATTAACTATGACTACACAGCATCAGGAACAACAGTACCTATCGCAAGACAATATCAATATCAACATCGTATGTAAAGTATGTAAGGAAAATTTTGTTGGTGTCGGAAATTTTACCGAACACATGAAGACCCATATGCCTCACGAGCAAGTATACGAAGAAGATGTTATGGGTGCCACACGTATAGAAATGGTCGATTTATCAGAAACATTAAATATGGATAAAAGTGCATATCCCTGCGCcttctgtaataaaaaatatatttggcaTAAATTCCTGGTGACGCATTCCAAGTGTCATAAAACTCCAGCACCATTTATATGCACGATATGTGGCCAGAGTTTTGATTGTTTATACTACGATCATATGAAGACACATATATTAAGTGAAGGGCGGACGTGTTCCAAGTGTAGTGAAAATTTTGCTACTCTCAAAGCCCTAAAGCAGCATGTTAGAACGGTGCACAATCCTCATCTTAGTGGAGATGCTAATCATCAGCATAAGTGTAGCATATGTGGAAAGCATTATAAAGCGTTATCGTATCTAAAAGAACACGAGCGGACGCATACAGGGGAGAAACCGTATAAATGTGATGTTTGTGGGAAAGCGTTCGCCAAATATGGTTGCTGGGCCGAACACAAAAAAACTCATTCGATTGTTAAAGCCTTTAAGTGCCCTATGTGCCCGAAAGCCTTCACGAAACGAAGGTATCTAAAGGCACATCTCCTTAGACATCCGAAAACATTAGATCTCGATAAAATATTCGTTGAAGATCGGGATGGTGAGTTGCCTAgcaggaaatttttatttgcaccGAATAAACCAAAACCCGTTCCAAAAGTGCAACCAAAATTGGAATGTCCGATATGTTATAAGGAGTTTAAGAAGATGAGATATTTACGGTCGCATGTTATACGACATCCAGAAGATTTTGTACGACAGAAGCTAGGTTTAAAGCCAGGAATGCCTATACCGGCTCTATTACCGGCCGTGCTAAATAGAAAGTCGGCTATGACAGCAGCAACAGAAAGCAATGAACAAGAGTTGACGAACATTCAGATAGAAACCAAACTTGAGATGTCGTCTGAAGATGAATCGACAGATGAGGAGAATATAGGTGAAGAAGAAGAGGAAGCTGTCGGCTTGGAAAAAGGGGAAGTCAAAGCAGATATTGAGTACGCGGATaatgattttttcaataatgAAGGATTTAACGAGGACGAGGAGTTTGATGAAAATATGGTGAAGCAACAAATTTCCAGCCCCGAAGAAGTCAATAACATCGCGCCCCACGATAGTAGCAACAATAATACTGAGATAGTTGATAACAATATAAAACCCACAGTTGAAGAAATCTTACCAATCCTAACGGAAATGCCTTCGGAACCAATCAACCTTTGTTGTACTATATGCCAAAAGTCATTCAACCAAGTTAAATTACTGCGAGATCACGAACAAGTTCATTACGGCGAAAATCCATATAAATGCAGCTACTGTAATACAGTATTTGTAATGTGGGCTCGGTATGAAGATCACATGACATTTGAACATAGTGACTACCCGATTCTTTGCGATGCGGATGaagagaaaaaatttaaaagttttagtcGATATTTTAACACCGAAGAAAAATCGTTTACATGTAGAACATGTGAGGATACATTTTTAACCGAAAACATGCTAAACGAACACGAGGATATGCATTTAGGTGAGGAACCATTAAAATGCAATGTGTGTACTGAATATTTTGCTATACAATCAAAGTACACGGAACATTTAAAATTGCACGGTATCGAAAGCGAATCTATAGAACATGCGGACGAAGATGAAGAGGACGAGGAGGATGTAAAAAGtgaaattgaaatcgaaattaaaagtGAGAATGACACAAGTGAACGTAATGGCAATGAAGGACGTGTGCTTCGAAGCCGAGcgattaaaaatagaaattcgaATTTACGTAATCATCGGATACGTCAGTTGAGACGAACGACTcggaaaataattgaaaaagaagaAGAGTCCGAACATGATGAGCAAAGTAGTGATGAAAAAGAGGTAGTTCAGGAGAACCAGGATGAGGATGAAGAAGAAATCGGGTTGAATATAAAAGAAGAAGTGAAGGAAAATTCCAAGAAACGTTTCAAATGTAAAATCTGTGGTAAACTATATACAAGTCTATTCTATCTAAAGGAACACCTATCGATCCATTCTGGAAACCGTCCTCACAAGTGCGAAACATGTGGCAAAACGTTCGCCGCCTCATCATGTTATCGGGAACATCTGGAACTGCATTCCTCGCAGAAGAATCACAAGTGTGATGTATGTGGAATGACTTTTGCTGTAGCTCGATATTTAAAAGCTCATATGCGTAGACATGCACAAAAAATTCTTCCAGATGGTGGTAAAAAATATAACTGTCCGCAATGCGAGAAGAAATACCAATCTAAGACAGCGCTGGTTGAGCACATGAAAATTCACACGGGTGAAGCACCATTTAAATGTACTTATTGTGGTAAAGTTTTCATGCTCTCCTCATCATTTCGCGACCACATGCTTAAACACGAAAACGTCGAAATGCATCAATGCCCATTCTGTCCAAAAAGCTTTATAAAAGCGCGTTACTTACAACAGCATTTGGTGCGGCACATTCAAAAATTGGACACCGAAGATAATGCAGAGTTGGCAACTAAtccgaaaaataataataccaaaGCCCAATTTGATGACGAATTAGAGGATAACACGAGCAGCAGTAGTGATACAAACTCAGaagatgaattttttaaaacaccgGCAATAGAAGATGATCAAACACTTgtgtaa
Protein Sequence: MERYTLAIKQENGYEITESGIINGINSLGENITIAQYEIQPQQQIHHGTMMLQHPQIIIHQQRVPQQQQHHILQQQHHHIQQIQHITPSSTPNHLQHHTIHIHNEEESNGSNSILYTNNTHSQCTTPHIQIQIHRADGSRPSSVQHIPAELVQVSSPLQVQSPHYHNNQHQQIIIHQPVTTIVEELQPQDLEIAHQEEIITIPAQIIQKVECPALTMTTQHQEQQYLSQDNININIVCKVCKENFVGVGNFTEHMKTHMPHEQVYEEDVMGATRIEMVDLSETLNMDKSAYPCAFCNKKYIWHKFLVTHSKCHKTPAPFICTICGQSFDCLYYDHMKTHILSEGRTCSKCSENFATLKALKQHVRTVHNPHLSGDANHQHKCSICGKHYKALSYLKEHERTHTGEKPYKCDVCGKAFAKYGCWAEHKKTHSIVKAFKCPMCPKAFTKRRYLKAHLLRHPKTLDLDKIFVEDRDGELPSRKFLFAPNKPKPVPKVQPKLECPICYKEFKKMRYLRSHVIRHPEDFVRQKLGLKPGMPIPALLPAVLNRKSAMTAATESNEQELTNIQIETKLEMSSEDESTDEENIGEEEEEAVGLEKGEVKADIEYADNDFFNNEGFNEDEEFDENMVKQQISSPEEVNNIAPHDSSNNNTEIVDNNIKPTVEEILPILTEMPSEPINLCCTICQKSFNQVKLLRDHEQVHYGENPYKCSYCNTVFVMWARYEDHMTFEHSDYPILCDADEEKKFKSFSRYFNTEEKSFTCRTCEDTFLTENMLNEHEDMHLGEEPLKCNVCTEYFAIQSKYTEHLKLHGIESESIEHADEDEEDEEDVKSEIEIEIKSENDTSERNGNEGRVLRSRAIKNRNSNLRNHRIRQLRRTTRKIIEKEEESEHDEQSSDEKEVVQENQDEDEEEIGLNIKEEVKENSKKRFKCKICGKLYTSLFYLKEHLSIHSGNRPHKCETCGKTFAASSCYREHLELHSSQKNHKCDVCGMTFAVARYLKAHMRRHAQKILPDGGKKYNCPQCEKKYQSKTALVEHMKIHTGEAPFKCTYCGKVFMLSSSFRDHMLKHENVEMHQCPFCPKSFIKARYLQQHLVRHIQKLDTEDNAELATNPKNNNTKAQFDDELEDNTSSSSDTNSEDEFFKTPAIEDDQTLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01054596; iTF_01457773; iTF_01052500; iTF_01053667; iTF_01460504; iTF_01456680;
90% Identity: -
80% Identity: -