Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:6057348-6060815[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00051 0.19 15.0 0.2 2 23 238 259 237 259 0.97

2 16 1.7 6.4e+02 4.0 3.4 1 23 319 339 319 339 0.81

3 16 8.1e-05 0.03 17.6 0.8 3 23 347 368 346 368 0.97

4 16 0.00024 0.091 16.1 4.4 1 23 380 402 380 402 0.98

5 16 0.00035 0.13 15.6 1.1 1 23 408 430 408 430 0.99

6 16 1.7e-06 0.00062 22.9 1.1 1 23 436 458 436 458 0.98

7 16 0.00089 0.33 14.3 0.6 2 23 499 520 498 520 0.96

8 16 0.00045 0.17 15.2 3.1 1 23 679 701 679 701 0.97

9 16 0.0024 0.89 12.9 0.6 1 23 707 730 707 730 0.93

10 16 0.39 1.5e+02 6.0 0.1 2 23 788 809 787 809 0.96

11 16 0.00011 0.042 17.1 1.3 1 23 929 951 929 951 0.98

12 16 0.0016 0.61 13.5 3.3 1 23 957 979 957 979 0.96

13 16 3.7e-06 0.0014 21.8 1.2 1 23 985 1007 985 1007 0.98

14 16 0.00012 0.045 17.0 0.9 1 23 1019 1041 1019 1041 0.98

15 16 0.00034 0.13 15.6 2.2 1 23 1047 1069 1047 1069 0.98

16 16 6.8e-05 0.025 17.8 1.7 1 23 1075 1097 1075 1097 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00051	0.19	15.0	0.2	2	23	238	259	237	259	0.97
2	16	1.7	6.4e+02	4.0	3.4	1	23	319	339	319	339	0.81
3	16	8.1e-05	0.03	17.6	0.8	3	23	347	368	346	368	0.97
4	16	0.00024	0.091	16.1	4.4	1	23	380	402	380	402	0.98
5	16	0.00035	0.13	15.6	1.1	1	23	408	430	408	430	0.99
6	16	1.7e-06	0.00062	22.9	1.1	1	23	436	458	436	458	0.98
7	16	0.00089	0.33	14.3	0.6	2	23	499	520	498	520	0.96
8	16	0.00045	0.17	15.2	3.1	1	23	679	701	679	701	0.97
9	16	0.0024	0.89	12.9	0.6	1	23	707	730	707	730	0.93
10	16	0.39	1.5e+02	6.0	0.1	2	23	788	809	787	809	0.96
11	16	0.00011	0.042	17.1	1.3	1	23	929	951	929	951	0.98
12	16	0.0016	0.61	13.5	3.3	1	23	957	979	957	979	0.96
13	16	3.7e-06	0.0014	21.8	1.2	1	23	985	1007	985	1007	0.98
14	16	0.00012	0.045	17.0	0.9	1	23	1019	1041	1019	1041	0.98
15	16	0.00034	0.13	15.6	2.2	1	23	1047	1069	1047	1069	0.98
16	16	6.8e-05	0.025	17.8	1.7	1	23	1075	1097	1075	1097	0.97

Sequence Information

Coding Sequence: ATGGAGCGTTATACATTGGCcataaaacaagaaaatggATACGAAATTACGGAAAGCGGTATTATCAATGGCATTAATAGCCTCGGTGAAAATATAACAATTGCCCAGTATGAAATCCAACCGCAACAACAGATTCATCATGCTACAATGATGATACAACATCCACAAATTATTATACACCAGCAAAGAATACCACAGCAGCATCAACATCATATAttgcagcaacaacaacatcacCTTGTACAACAGATTCAACATATAACGCCATCCTCGACCCCAAATCACCTACAACATCACacaattcaaatacataatgaAGACGAGTCTAATGAGGGTAATTCCATATTGTATACAAATAATACACATTCGCAGTGTACTACGCCtcatatacaaatacaaattcatcACGCGGATGGAAGTAGGCCGGATTCAGTGCAGCACATACCAGCGGAATTAATGCAGGTGTCTAGCCCGTTAGAACTACATTCACCACATTATCATAATAATCAACATCAACAGATAATAATTCATCAGCCTATGACCACAATTGTAGAAGAACTACAACCGGAGGAACTTGAAATAGCACATCAAGAAGAAATTATTACGATACCAGAGCAAATAATACACAAAGTTGAGTACCCAGAATTAGCTATAACACCGCAGCATCAGGAACAACAGTACCTATCTCAAGACAATATCAACATAAACATAGTATGTAAGGTGTGTAaggaaaattttgttggagttgATAATTTTACCGAACACATGAAAACCCATATGCCACACGAACGAGTGTACGAAGATGTTATGGGTGCCACTCGAATAGAAATGGTAGATTTATCAGAAACACTGAATATGGATAAAAGTGCATATCCATGCGCCTTCtgtaacaaaaaatacatttggCATAAGTTCCTGGTGACGCATTCCAAGTGTCATAAAACTCCAGCTCCATTTATATGCACGATATGTGGCCAGAGTTTTGATTGTTTGTACTACGATCATATGAAAACTCATATTTTGAGTGAAGGGCGTATTTGTTCCAAATGTAATGAGAATTTCTCAACACTCAAAGCGCTAAAGCAGCATGTAAGGACCGTCCATAACCCACATCTTAGTGGAGACGCTAATCACCAGCACAAGTGTAGCATATGTGGAAAACATTATAAAGCGTTGTCATATTTAAAAGAACACGAACGGACCCATACTGGTGAGAAACCATATAAATGTGATGTTTGTGGTAAAGCATTCGCCAAATATGGTTGCTGGGCCGAACACAAAAAAACCCATTCGATTGTTAAAGCCTTTAAGTGCCCTATGTGTCCAAAAGCCTTCACGAAACGAAGATATCTAAAGGCACATCTCCTAAGACATCCAAAAACACTAGATCTCGATAAAATATTCGTTGAAGATAGAGACGGTGAATTGCCTagcagaaaatttttatttgcaccGAATAAACAAAAACCTGTTCCAAAAGTGCAGCCGAAATTGGAATGTCCAATATGTTATAAAGAGTTTAAGAAGATGAGATATTTGCGGTCGCATGTTATACGCCATCCAGAAGATTTTGTACGACAGAAGCTTGGTTTAAAACCAGGAATGCCTATACCACCTTTATTGCCGGCCGTACTAAATCGAAAGTCTGCTATGATAGCAGCATCAGAAAATAATGAACAAGAGTTGACGAATATTCAGATTGAAACCAAACTTGAGATGTCATCTGAAGATGAATCGACTGACGATGAGATTATGGGTGAAGAAGAGGAGGAATCCGTCGGTCTAGAAAAAGGGGAAGTCAAAGCCGATTTAGAGTATGCGGATAACGATTTCTTCAATAATGAAGGCTTTAACGAGAATGAGGaagaatttgatcaaaatacgGTGAAGCAACAAATTCCAAGTCCCGAGGAAGTTAATGGCAGTCCGCAGGATAgtaccaataataatattgatgtagttgataataatataaaaccTGCAGTCGAAGAAATGTTACCCACCCTTCCGGAAGCGCCGGTCGAACCAACCATTTTTTGTTGTACGATTTGCCAGAAGTCAttcaagcaaataaaattattgcgagaTCATGAACAAGTTCATTACGGTGAAAATCCGTATAAATGCAGCTATTGTAACACTGTTTTTGTGATGTGGGCTCGCTACGAAGATCATATGACTTTTGAACATAGTGACTACCCGATTTTATGCGATGCGGATGatgagaaaaaatttaaaaatcttggcCGATATTTTAACACCGAGGAAAAGTCGTTTACATGTAGAACATGTGAGGATACATTTTTAACTGAAAACATGTTAGAGGAACACGAAGATATACATTTAGGTGAGCAACCATTAAAGTGCCAAGTATGTGCTGAAGATTTTGCGATACAATCAAAATATGCGGAACATTTAAAAGCACACGGTACAGAAGACGATATGTTTGAGAAGGAGGATGAAGAACAAGAGGATGAGGAGCCTCTAAAAAGCGAGTATGAAGTCGAAATTACAAATGAGAATGACATAAGTCAACGTAATGGCAATGAAGGGCGTGTGCTTCGAAGTCGAGCGAATAAAAATAGGATTTCGAATTTACGCAATAATCACAGAACCAGGTTGAGACGGACGAAGcggaaaataatagaaaaagaagAGTCCGAGTGCGATGATCAAAGTAGTGATGAAAATCATAAAGATAGAATCGAACTCGAGGAGCCGAATGAAGAAGAAGAAACCGAGGCGCAGGTGAAGCAAGGCGTCAAGGAAGATTCCAAGAAACGGTTCAAATGTAAAATCTGTGGTAAACTGTATACAAGCCTTTTCTACCTAAAAGAACATTTATCGATTCATTCTGGTAAACGCCCTCACAAGTGCGAAACATGTGGCAAAACATTTGCCGCCTCATCCTGTTATCGAGAACATTTGGAATTGCATTCGTCACAAAAGAATCACAAGTGTGATATGTGTGGTATGACCTTTGCAGTGGCTCGCTATTTAAAAGCCCATATGAGAAGACATGTACAAAAATCTCTCCCGGATGgtggtaaaaaatataattgccCGCAATGCGAAAAGAAGTACCAATCTAAGACAACGCTGGTTGAACACATGAAAATTCACACGGGTGAAGCACCGTTTACTTGTACTTATTGTGAAAAAGTATTCATGCTCACATCATCTTTCCGCGATCATATGCTTAAACATGAAAATGTCGAAATGCATCAATGTCCATTCTGCCCAAAAAGCTTTATAAAAGCTCGTTACTTACAGCAGCATTTGGTGCGGCACATCCAAAAATTGGACACCGAAGATAATGCAGATGAGGCAGCTGATCCGAAAAACAATGACACCAAAACCCATTTTGATCAAGAGTTCGAAGAAAGTACGAGCAGCAGTAGTGATTCAGATTCGgaagatgatttttttaaaatgctaCCGCCAGGTGATGGTCAAACAGTTgtgtaa
Protein Sequence: MERYTLAIKQENGYEITESGIINGINSLGENITIAQYEIQPQQQIHHATMMIQHPQIIIHQQRIPQQHQHHILQQQQHHLVQQIQHITPSSTPNHLQHHTIQIHNEDESNEGNSILYTNNTHSQCTTPHIQIQIHHADGSRPDSVQHIPAELMQVSSPLELHSPHYHNNQHQQIIIHQPMTTIVEELQPEELEIAHQEEIITIPEQIIHKVEYPELAITPQHQEQQYLSQDNININIVCKVCKENFVGVDNFTEHMKTHMPHERVYEDVMGATRIEMVDLSETLNMDKSAYPCAFCNKKYIWHKFLVTHSKCHKTPAPFICTICGQSFDCLYYDHMKTHILSEGRICSKCNENFSTLKALKQHVRTVHNPHLSGDANHQHKCSICGKHYKALSYLKEHERTHTGEKPYKCDVCGKAFAKYGCWAEHKKTHSIVKAFKCPMCPKAFTKRRYLKAHLLRHPKTLDLDKIFVEDRDGELPSRKFLFAPNKQKPVPKVQPKLECPICYKEFKKMRYLRSHVIRHPEDFVRQKLGLKPGMPIPPLLPAVLNRKSAMIAASENNEQELTNIQIETKLEMSSEDESTDDEIMGEEEEESVGLEKGEVKADLEYADNDFFNNEGFNENEEEFDQNTVKQQIPSPEEVNGSPQDSTNNNIDVVDNNIKPAVEEMLPTLPEAPVEPTIFCCTICQKSFKQIKLLRDHEQVHYGENPYKCSYCNTVFVMWARYEDHMTFEHSDYPILCDADDEKKFKNLGRYFNTEEKSFTCRTCEDTFLTENMLEEHEDIHLGEQPLKCQVCAEDFAIQSKYAEHLKAHGTEDDMFEKEDEEQEDEEPLKSEYEVEITNENDISQRNGNEGRVLRSRANKNRISNLRNNHRTRLRRTKRKIIEKEESECDDQSSDENHKDRIELEEPNEEEETEAQVKQGVKEDSKKRFKCKICGKLYTSLFYLKEHLSIHSGKRPHKCETCGKTFAASSCYREHLELHSSQKNHKCDMCGMTFAVARYLKAHMRRHVQKSLPDGGKKYNCPQCEKKYQSKTTLVEHMKIHTGEAPFTCTYCEKVFMLTSSFRDHMLKHENVEMHQCPFCPKSFIKARYLQQHLVRHIQKLDTEDNADEAADPKNNDTKTHFDQEFEESTSSSSDSDSEDDFFKMLPPGDGQTVV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01458865;
90% Identity: iTF_01460504;
80% Identity: -