Basic Information

Insect: Timema cristinae
Gene Symbol: Rreb1
Assembly: GCA_002928295.1
Location: CM009484.1:7989749-8005030[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00023 0.034 16.0 0.4 1 23 127 149 127 149 0.97

2 16 7.6e-05 0.011 17.6 0.1 1 23 166 188 166 188 0.98

3 16 5.1e-06 0.00074 21.3 2.4 1 23 194 216 194 216 0.99

4 16 2.1 3.1e+02 3.6 0.1 1 23 342 366 342 366 0.82

5 16 0.12 17 7.5 1.4 2 22 372 392 372 395 0.89

6 16 5.5 8e+02 2.3 0.3 1 20 456 475 456 477 0.80

7 16 0.015 2.1 10.4 0.1 1 23 655 677 655 677 0.97

8 16 0.019 2.8 10.0 0.3 1 23 685 707 685 707 0.99

9 16 0.0019 0.28 13.1 2.3 1 23 713 736 713 736 0.97

10 16 0.0011 0.16 13.9 2.1 1 23 1005 1028 1005 1028 0.95

11 16 0.0043 0.63 12.0 0.3 3 23 1323 1343 1322 1343 0.98

12 16 0.022 3.3 9.8 5.1 1 23 1349 1372 1349 1372 0.97

13 16 0.0017 0.25 13.3 2.1 1 23 1414 1438 1414 1438 0.96

14 16 0.63 93 5.2 1.3 1 23 1555 1577 1555 1578 0.95

15 16 0.0044 0.65 12.0 0.5 3 23 1635 1655 1633 1655 0.96

16 16 0.01 1.5 10.9 5.9 1 23 1661 1683 1661 1683 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00023	0.034	16.0	0.4	1	23	127	149	127	149	0.97
2	16	7.6e-05	0.011	17.6	0.1	1	23	166	188	166	188	0.98
3	16	5.1e-06	0.00074	21.3	2.4	1	23	194	216	194	216	0.99
4	16	2.1	3.1e+02	3.6	0.1	1	23	342	366	342	366	0.82
5	16	0.12	17	7.5	1.4	2	22	372	392	372	395	0.89
6	16	5.5	8e+02	2.3	0.3	1	20	456	475	456	477	0.80
7	16	0.015	2.1	10.4	0.1	1	23	655	677	655	677	0.97
8	16	0.019	2.8	10.0	0.3	1	23	685	707	685	707	0.99
9	16	0.0019	0.28	13.1	2.3	1	23	713	736	713	736	0.97
10	16	0.0011	0.16	13.9	2.1	1	23	1005	1028	1005	1028	0.95
11	16	0.0043	0.63	12.0	0.3	3	23	1323	1343	1322	1343	0.98
12	16	0.022	3.3	9.8	5.1	1	23	1349	1372	1349	1372	0.97
13	16	0.0017	0.25	13.3	2.1	1	23	1414	1438	1414	1438	0.96
14	16	0.63	93	5.2	1.3	1	23	1555	1577	1555	1578	0.95
15	16	0.0044	0.65	12.0	0.5	3	23	1635	1655	1633	1655	0.96
16	16	0.01	1.5	10.9	5.9	1	23	1661	1683	1661	1683	0.98

Sequence Information

Coding Sequence: aTGGACTCAACCGTAATGGGAAATGAAAGCATACATCAAGAATCCTCTCAGACTGATAACAACAAATATGTAAGAAAACAAGAATCCTTGAATCTACTAGACACGGGAAGAAAATCCTGTGAATCAGACATCGATACTTTAGAACATGACAACGAATGTGAAAAGTTACCCAATAACAGCACAGATAACAAACCGTTTGAAGTTGCTAGTAAGGAATCCATAGCAATAAACAAAGTTTATGAAAGACTCAAAGATATAACTGAAGCAAAAAATGATAATGATAAGGATTGTGAAAACTTGGATATGCCAGAAAATTGTTCTCTTGATTGCCTGTCCCCAAACAGTGAAAATAGTCAAATGGATGATTCAGATATGAAATTTGCCTGCCCAATCTGTGACATGATTTTATCTTCCCAGCATGAGTTTACTTTACACATTCGCTCACATAACAATAATGCAGAGTCATTAGTTTATCCTCTAGCATGCTTGAAGAACTACACCTGCCGTATCTGTGGCAAAGGGCTAAGTTCATCCAGTTCATTGGATCGTCATGTGTTAGTCCACTCTGGTGAGCGGCCATTTAAATGCATGACTTGTGGTGTTGCTTTTACAACAAATGGAAACATGCATAGGCATATGAGGACCCATAATCCCTCCCATGTGGAGGATAGTTCGGTTTTGATTTCCAAATGTGAATACACCAGTTATGAGAGTGATGGTAGTTCTGATAGTGTAGGATCAAGCAATAGCTTATCTGACAATCCAAGGAAAAGTCCTCATTTAGACACTTCTCAAGCTGGACCTGCAAAAAGACGAAGAGTTGATAGTGACGGTTTTCTTATTGAATCTAACAACAACACCAATAAACTTTCTGAGCcattatcatcattaaaatCGCATGTAGAGAATGGAATCAAGAGAAAGGCTTCCGATTTGCTGACACCCCCTGATTATGAAGGAGAAGAAATTGTTAGGAGGAACTTAAACCCTGTTACATATCATCAAAATGAATTTGTTCAACCATTCCAATGTCCTGTTTGTAAAAGAATTGATTTTGCATCGTTGTATGTTTTAGAGACACATCTTGAAGAAAGGCATCCTGATTATAAGGCCACGTGTTATCAGTGcgacttaatttttaaaaatcatcgaGCTTTAAATCTTCATCGTTTCATGGCCCAACATGATAATAGTGAAGAACACAACATTGTAAGGGCTAAGAAGAGTAAACATATTAATAGAGCATCCTCTGTCTTGGGTTTCAGAGACCTAACATTTGTAGACTTTTCTAGTGAAAAGTTCCCATACATTGCAAAAGTAATGTGTGAACAAAGTATGCATAGAGCAACTAGTGCCTTTCATAAGTTCCAATGCCAAAAGTGTGCAAGAGCTTTTCCATGTGGTAGTGCCTTGAGCATTCACCGCCAGGCGTGCTTGACTTCACGTGAAAAAGTGGATTTCAACCACACATATGACCATGATAGTTTTCATGGAGATGAATTTCCATCAAGTGACTGTGATACTCCAACAGATCTGAGCAGCAAAAAGAAACCTACACAGCATTTACGATACGAAAAATCTTCAGATTGTGAGTCTGAAGAAGAACAAAAAAGAGAAGATTTTTTTGCCCATTTAGATCTGCAGACTAAATCAGTGTGTTTATCATCGCCATTGTCTTCAGAAGATTTCCGTAGGGATGAGAGGTTTGAAAATGATTCTTACTTTAATTCTGTCAATGGTAATAAATGTGATAATGGAAAAGATCTTGCAGATATACAGAGCATTATATCTGTCACATCAGCAGGAGGGCTGCTTaatgatttatcaaaatctccaCAACCCAATGGAAATGATATAACACCTCCAGATTCTGGGATAAAATCCTCAGATTCAGGAACAGGGGAAGAAGAACAGCAGGATTGTTTTGCATCAGAGTTTCgtaaaatgaagttaaaagGGGAATTTCCATGCCGTGTATGTACTCTCGTGTTTCCAAATCTACGTGCTCTCAAAGGTCATAATAGAGTTCATCTTACAGCCAGCTCAGGACTGTATCGGTGTAACATGTGCCCATATTCCAACATTGATAAAGGAATCCTAGTGCGACACATGCGAACTCATAACGGGGACCGACCATATGAATGTGCTCTCTGTAATTACGCATTTACTACCAAGGCAAATTGTGAAAGGCATTTGCGTAACAGGCACTCAAAACTTTCTCGAGATGACGTAAAAAATTCCATTATCTATCATCCTTCAGAAGATCCTATAAATGACCCTGAAATTCAGCCAAAGCTAACCACTCGAGAAGATGTGAAGAGATCTTTAGTTTTCAGCACCAACTTGTCAACTGATGAAACCAATAACATGGATCTCTCCAACCAAAGCTTTACAGAGGAACATCAAAAAGATGGTCAAACAAAGTTGCATGAAATTTCAAATAGACTCTCATTTACTGATAATGAACCAAATACTATAGGTAAACCTACCTTGGATGATCACAATGAAGAAATAAATCATACACCAACATTTTCAGTTAATGCTCTACCAAAAACTCTAGTCCCTATAACAAATATAGCTGATTCTAACAACAAACAGATTCGTCCGTGGGTAACTCATGAAGTTGCAACAATGACTCATTTCAGAGACAACACGGTTGATGAAGTTAATGATATTGAAACTGATAGTAACGATGATCATTCTGATCGTGAAGACAATCATACAACTGAAAATTCAAATGTCCTAGTCATTATTaccaaaaataactttaactatAGTCATACTAACAACATGCTCACCAAATTACCTATTCATGACCAAAGAACATTGAAAGATCCAATTGAGACTATAAATCCATCAGCTATTACAACCAATTTGGAAAATTCCTATTCCAGCGATGATGATATGAATGCTCCTTTAGATCTCAGTATGGATGCCTTAGACTTGAGTAAGAAGAGGGCAAATGAAAAACAACCCGACACTAAGCAGAGAAGGTATCGAACTGAGAGGCCATTTGCATGTGAACATTGTTCTGCACGATTCACTCTTCGCTCTAATATGGAGAGGCACATAAAACAACAACATCCTCAGTTCTGGAGCCAACGTCAGAGAAACAGTTCTGGATCTGTTGGACGCAGAAGTCATCCAGCAGCAGTGCCGACTTCTGTCAACCAGGTTTTGACCACTCAACAGTCTCAAGACTCTAGGAGTTCAGTGGATAGTTTCAGTCAAACTTCATCAAAAGGATctcatttttctataaatgttgTTTCAAGTGACCCAACAGATTATAGATCCATGCCTTTACTTGAATGGAGGGGTAGTGAAAAGATGCCAAAGATAGAAGAATCCTACACCGAGGAAGTGTTGGATAATATTCACAAAACCAAAGATATATCTAGTGTTGGTGCtatcaacaatttaaataatatagctttTATTTCTGAGGAAGTAAGGTTTGCGATATCTCAGCAGTTAAAATCAAAACTACACCAGCCTCCCGCAGTACCTCTAGGAGAGATATCTGACATAAAATGTGAGGCACGCGGTGACATGGATGAAGAAGATGAAAATGATGGATTGGTGATTGATGAAGAAAAAGGTGAAGTTGAAGAAGGTAATGAATACGGTAACCAGAAAGGGGTACAAACCAAAGAACAACAGAATGGAAGTAGGGATGAAGGAGTAGTGGATCTGGCAAGTGTATCAAGACTTTTGGACAACGCCACTACACAGAATCAAGCATTCCAGCAGTATTTCCAGGGAACACAAGATGCTGATGGGGAAGAGGAAGGAACTGAATACGGAAGGGAAGAAGCTAGTGAGGATGATGAAGAAGGACTAGTAGCTGGAAGCAATAGTGAAGGAAACAACTCGGGCAGTGACGAAAACAGatctgAGTCAGATATAAATCCAGGTacagaaaaaaagaagagtgCGTACTCCCTTGCACCTAATAGAGTCGCGTGCCCATACTGCCTTCGCAAATTTCCGTGGTCCTCATCTCTGCGTCGACATGTGTTGACACATACAGGACAAAAGCCATACAAGTGTCCACATTGTCCACTACTGTTCACCACAAAGTCAAACTGTGACCGTCATTTGCTCAGAAAACACGGCAGCACATCAGCCACAACTTCTAATAACAGTAACAATGGTATCGAGACATCTCAAGGAAACGGGACTCCTACAGGAGCATCAAATCCAAGCTATACGATGAGAAACGTTCCTGAGAGGCCTTTCAAGTGCAATTTCTGTCCAAGTTCTACGTTCTCGACGCAGAGCAACTTGAAGAAACACGTCGCCACCAAGCATGGTAGCCACTCTTGCCCGACAAGTCCTGCAGCTGCTACCACTAGGAACACATATTCCTCTGGGGATGAGACCTATCATCAAACAACCAGAACAATTGATAGTCGTGGTGGTGGAGATGATAGCCATGATAGTGTAAATGAAGATGTATCAGATGAAAGGTTGACATATCCTAATCCCGTAAACAGAACCACTGATATTGGTGAAGGGGGTATCGAGAGCGTGCTTGGTCATCCTGCAATAGATCTGAGAACTAGCATTCCTTCACTTGGAGCTACACACGATAGTGTTGTGCCAAAGACTTCAATAGCGCTCGAAATCCATGGATCTACCACATCTTCGGAGCTACCTTTTAAATGCCACTTGTGTGAAGGAAGTTACGCAGAAAGGCAGGAAGCTTTGGATCATATCCGGGAACATCACCCTACAGAGTTTGATCTACTTGTGACTAAAGGAGCACTGGAGGTATCTACACATGAGGAGAATAATGGGACTAGTCACATCACGTCACAGGAAGAAGGGAATGGAGGGGAAGAAAATCTGGAACAACTCAGAGGAAAGTTTCCAGACTATGCTAACAGAAAGGTAATGTGTGCATTCTGCCTGCGTCGATTCTGGTCCGCTGAAGATTTGCGACGACACATGCGCACACACACAGGTGAGCGACCCTTCTCATGTGACATCTGTCGAAGGCGCTTTACTCTGAAACATAGCATGCTGCGCCACCGTAAGAAACATAGCATCACTGGCACTTCGTACGTGTCTCCCAACTCTGAAGATGTCTCCATTGACAGGTCGATCATTGACAAAGTTCTCTTATCCAAGTCTGCCGATGATGCTGCTAAGTTGTTGGGTGTAAGAAATTCAAGTCAGGAGTAG
Protein Sequence: MDSTVMGNESIHQESSQTDNNKYVRKQESLNLLDTGRKSCESDIDTLEHDNECEKLPNNSTDNKPFEVASKESIAINKVYERLKDITEAKNDNDKDCENLDMPENCSLDCLSPNSENSQMDDSDMKFACPICDMILSSQHEFTLHIRSHNNNAESLVYPLACLKNYTCRICGKGLSSSSSLDRHVLVHSGERPFKCMTCGVAFTTNGNMHRHMRTHNPSHVEDSSVLISKCEYTSYESDGSSDSVGSSNSLSDNPRKSPHLDTSQAGPAKRRRVDSDGFLIESNNNTNKLSEPLSSLKSHVENGIKRKASDLLTPPDYEGEEIVRRNLNPVTYHQNEFVQPFQCPVCKRIDFASLYVLETHLEERHPDYKATCYQCDLIFKNHRALNLHRFMAQHDNSEEHNIVRAKKSKHINRASSVLGFRDLTFVDFSSEKFPYIAKVMCEQSMHRATSAFHKFQCQKCARAFPCGSALSIHRQACLTSREKVDFNHTYDHDSFHGDEFPSSDCDTPTDLSSKKKPTQHLRYEKSSDCESEEEQKREDFFAHLDLQTKSVCLSSPLSSEDFRRDERFENDSYFNSVNGNKCDNGKDLADIQSIISVTSAGGLLNDLSKSPQPNGNDITPPDSGIKSSDSGTGEEEQQDCFASEFRKMKLKGEFPCRVCTLVFPNLRALKGHNRVHLTASSGLYRCNMCPYSNIDKGILVRHMRTHNGDRPYECALCNYAFTTKANCERHLRNRHSKLSRDDVKNSIIYHPSEDPINDPEIQPKLTTREDVKRSLVFSTNLSTDETNNMDLSNQSFTEEHQKDGQTKLHEISNRLSFTDNEPNTIGKPTLDDHNEEINHTPTFSVNALPKTLVPITNIADSNNKQIRPWVTHEVATMTHFRDNTVDEVNDIETDSNDDHSDREDNHTTENSNVLVIITKNNFNYSHTNNMLTKLPIHDQRTLKDPIETINPSAITTNLENSYSSDDDMNAPLDLSMDALDLSKKRANEKQPDTKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRNSSGSVGRRSHPAAVPTSVNQVLTTQQSQDSRSSVDSFSQTSSKGSHFSINVVSSDPTDYRSMPLLEWRGSEKMPKIEESYTEEVLDNIHKTKDISSVGAINNLNNIAFISEEVRFAISQQLKSKLHQPPAVPLGEISDIKCEARGDMDEEDENDGLVIDEEKGEVEEGNEYGNQKGVQTKEQQNGSRDEGVVDLASVSRLLDNATTQNQAFQQYFQGTQDADGEEEGTEYGREEASEDDEEGLVAGSNSEGNNSGSDENRSESDINPGTEKKKSAYSLAPNRVACPYCLRKFPWSSSLRRHVLTHTGQKPYKCPHCPLLFTTKSNCDRHLLRKHGSTSATTSNNSNNGIETSQGNGTPTGASNPSYTMRNVPERPFKCNFCPSSTFSTQSNLKKHVATKHGSHSCPTSPAAATTRNTYSSGDETYHQTTRTIDSRGGGDDSHDSVNEDVSDERLTYPNPVNRTTDIGEGGIESVLGHPAIDLRTSIPSLGATHDSVVPKTSIALEIHGSTTSSELPFKCHLCEGSYAERQEALDHIREHHPTEFDLLVTKGALEVSTHEENNGTSHITSQEEGNGGEENLEQLRGKFPDYANRKVMCAFCLRRFWSAEDLRRHMRTHTGERPFSCDICRRRFTLKHSMLRHRKKHSITGTSYVSPNSEDVSIDRSIIDKVLLSKSADDAAKLLGVRNSSQE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448914; iTF_01450887; iTF_01446920; iTF_01449919; iTF_01447850; iTF_01445108;
90% Identity: iTF_01448914;
80% Identity: -