Basic Information

Insect: Timema genevievae
Gene Symbol: RREB1
Assembly: GCA_902155825.1
Location: CABFWO010002798.1:58399-72528[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0001 0.019 17.3 1.6 1 23 123 145 123 145 0.98

2 16 0.00011 0.02 17.3 0.1 1 23 162 184 162 184 0.98

3 16 1.8e-06 0.00034 22.8 2.7 1 23 190 212 190 212 0.99

4 16 2.9 5.5e+02 3.3 0.1 1 23 338 362 338 362 0.82

5 16 0.068 13 8.5 2.9 2 22 368 388 368 391 0.89

6 16 4.3 8e+02 2.8 0.4 1 20 452 471 452 473 0.80

7 16 0.02 3.8 10.1 0.1 1 23 651 673 651 673 0.97

8 16 0.027 5 9.7 0.3 1 23 681 703 681 703 0.99

9 16 0.0027 0.5 12.9 2.3 1 23 709 732 709 732 0.97

10 16 0.0016 0.29 13.6 2.1 1 23 1253 1276 1253 1276 0.95

11 16 0.006 1.1 11.8 0.3 3 23 1566 1586 1565 1586 0.98

12 16 0.031 5.8 9.5 5.1 1 23 1592 1615 1592 1615 0.97

13 16 0.0043 0.81 12.2 2.9 1 23 1657 1681 1657 1681 0.96

14 16 0.88 1.6e+02 5.0 1.3 1 23 1798 1820 1798 1821 0.95

15 16 0.0062 1.2 11.7 0.5 3 23 1878 1898 1876 1898 0.96

16 16 0.014 2.6 10.6 5.9 1 23 1904 1926 1904 1926 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0001	0.019	17.3	1.6	1	23	123	145	123	145	0.98
2	16	0.00011	0.02	17.3	0.1	1	23	162	184	162	184	0.98
3	16	1.8e-06	0.00034	22.8	2.7	1	23	190	212	190	212	0.99
4	16	2.9	5.5e+02	3.3	0.1	1	23	338	362	338	362	0.82
5	16	0.068	13	8.5	2.9	2	22	368	388	368	391	0.89
6	16	4.3	8e+02	2.8	0.4	1	20	452	471	452	473	0.80
7	16	0.02	3.8	10.1	0.1	1	23	651	673	651	673	0.97
8	16	0.027	5	9.7	0.3	1	23	681	703	681	703	0.99
9	16	0.0027	0.5	12.9	2.3	1	23	709	732	709	732	0.97
10	16	0.0016	0.29	13.6	2.1	1	23	1253	1276	1253	1276	0.95
11	16	0.006	1.1	11.8	0.3	3	23	1566	1586	1565	1586	0.98
12	16	0.031	5.8	9.5	5.1	1	23	1592	1615	1592	1615	0.97
13	16	0.0043	0.81	12.2	2.9	1	23	1657	1681	1657	1681	0.96
14	16	0.88	1.6e+02	5.0	1.3	1	23	1798	1820	1798	1821	0.95
15	16	0.0062	1.2	11.7	0.5	3	23	1878	1898	1876	1898	0.96
16	16	0.014	2.6	10.6	5.9	1	23	1904	1926	1904	1926	0.98

Sequence Information

Coding Sequence: ATGGGAAATGAAAGCATACATCAAGAAACCTCTCCGACTGATAACAAGATATATGTAAGAAAACAAGAATCCTTGAAGCTACAAGACACAGGAAGAAAATCCAGAGGATCAGACATCGATATTTTAGAACATGACAACGAATGTGAAAAGCTACCCAATGACAGCACAGACAACAAACTGTTTGAAGTTGCTAGTAAGGAATCCATAGCATTAAGCAAGAAAggttatgaaatatttaaagatataactgaagcaaaaaatgataattataaagAGTGCGATAGCTTGGATATGGCAGAATATGGTTCTCTTGATTGCCTGTCCCCAAATAGTGAAAGTAGTCAAATGGATGATTCAGATATGAAGTTTACCTGCCCAATCTGTGACACGGTTCTATCTTCCCAGCATAAGTTTACTTTACACATTCGCTCACACAACAATAATGCAGAGTCATTAGTTTATCCTCTCGCAAGCTTAAAGAACTACACTTGCCGTATTTGTGGCAAAGGGCTAAGTTCATCCAGTTCATTGGATCGTCATGTGTTAGTCCACTCTGGTGAGCGGCCATTTAAATGCACAACTTGTGGTGTTGCTTTCACAACAAATGGAAACATGCATAGACATATGAGAACCCATAATCCCTCCCATGCCGGGGATAATCTGGTTTTGAATTCCAAATGTGAATACACCAGTTATGAGAGTGACGGTAGTTCTGATAGTGGAGGATCAATCAATAACATATCTGACAATCCTAGGAAAAGTCCTCACTTGGACACTTCTCAAGCTGGACCTGCAAAGAGACGTAGAGTTGATAGTGATGGTTTTCTTATCGAATCAAACAACAACACCAATAAACTTTCTGAGCCATTATCATCAGTAAAATTGCATGTAGAAAATGGAATCAAGAGAAAGGCTTCTGATTTACTGACACCCCCTGATTATGAAGGAGAAGAAATTGTGAGGAGGAACGTAAACCCCGTTACATATCATCAACATGAATTTGTTCAACAATTCCAATGTCCTGTTTGTAAACGAATTGATTTTGCTTCGCTATATGTGTTAGAGACACATCTTGAAGAAAGGCATCCTGATTATAAGGCTACATGTCATCAGTgtgacttaatttttaaaaatcatcgaGCTTTAAATCTTCATCGTTTCATGGCCCAACATGATAATAGTGAAGAACACAACATTGGAAGGGTTAAGAAGAGTAAACATATTAATAGAGCATCCTCTGTCTTGGGTTTCAGAGACCTAACATTTGTAGACTTCTCGAGCGAAAAGTTCCCATACATTGCAAAAGTAATGTGTGAACAAAGTATGCATAGAGCAACTAGTGCCTTTCATAAGTTCCAATGCAAAAAGTGTGCGAGAGCTTTTCCGTGTGGTAGTGCCTTAAGCATTCACCGTCAGGCGTGCTTGACTTCATGTGAAAAAGTGGATTTCAACCACCCATATGACCCTGATAGTTTTCATGGAGATGAATTTCCATCAAGTGATTGTGATACTCCAACAGATCTGAGCAGCAAAAATAAACCTACGCAGCATTTACGATACGAAAAATCTTCAGATTGTGAGTCTGAAGAAGAACAAAAACGAGAAGATTTTTTTGCCCATTTAGATCTGCAGACTAAATCAGTGTGTTTATCATCACCATTGTCTTCAGAGGATTTCCGTAAAGAAGATAGGTTTGAAAATGATTCTTACTTTAATTCTGCCAATGGTAATAAGTGTGAGATTGGAAAAGATCTTGCAGATATTCAGAGCATTATATCTGTCACATCAGCAGGGGGGCTGCTTAATGACTTATCAAAATCTCCACAGCCGTATGGAAATGATATAACACCACCAGATTCTGGAGTAAAAGCCTCAGATTCAGGAACAGGGGAAGAAGAACAGCAGGATTGTTTTGCATCAGAGTTtcgtaaaatgaaattaaaaggGGAATTTCCATGTCGTGTATGTACTCTCGTGTTTCCAAATCTGCGTGCTCTCAAAGGTCATAATAGAGTTCATCTCACAGCCAGCTCAGGACTGTATCGATGTAACATGTGCCCATATTCCAACATCGATAAAGGAATCCTAGTGCGACACATGCGAACTCATAACGGGGACCGACCATATGAATGTGCTCTCTGCAATTACGCTTTTACTACCAAGGCAAATTGTGAAAGGCATTTGCGTAACAGGCACTCAAAACTTTCTCGAGATGATGTAAAAAATTCTATTATATATCATCCTTCAGAAGATCCTATAAATGACCCTGAAATTCAGCCAAAGCTAACCACTCGAGAAGATGTTAAGAGATCTTTAGTTTTCAGCACCAACTTGTCAACTGATGAAACCAACAACATGGATCTCTCTAACCAAAGCTTTACAGAGGAACATCAAAAAGATGGTCTAGcaaatttgcatgaaatttcaaataaactctCATTTACTGATAATGAACCTAATACTATAGGAAAACCTATCTTGGATGATCACAATGAAGAAATAAATCATACCCCAACATTTTCTAATAATTCTTTACCAAAAACTCTAGTCCCTATAACAAATATATCTGATTCTAACATCAAACAGATTCGTCCATGGGAAACTCATGAAGTTGCAACAATGACTCATTTCAGAGACAACCAGGTTGATGAAGTTAATGATATTGAAACTGATAGTAACGATGATCAATCTGATCGTGAAGACAATCATACAGCTGAAAATTCAAATGTCCTAGTCATTATTaccaaaaataactttaactaCAGTCATACTAACAACATTCTAACCAAATTACCTATTAATAACCAAAGAACATTGGAAGATCCCATTAAGACTATAATTCCATCAGctattacaaacaatttggAAAATTCTTATTCTAGCGATGTTGATATGAACGCTCCATTAGATCTCAGTATGGATGCCCTGGACTTGAGTAAGAAGAAAGCAAATGAAAAACCACCTGACATTGTCACAAATATTAATGATGATTTTGAACCACAAGATTTGTCCAAAAAGTCTATGAAACACAATCCTGaatacaataacaacaataaactCTCAAAGAAATCTCTATTTATTTCATCTCGAAAATCCCAACACTAtgctaacattaataaaaatcatagtACTGCTCAAGAATTGTACaacaatttaaatcataaaattagtCCACCTCCAAGCCCAGGTCCAAATACGGTCCCAAAAATCGAGATGAAAACAGGGGGACTTTACACAGGAAGCTCGCATCTAAACCCTATTTATCTCAATAACAATGGTTTCCATTTTCCATCACAATCTTTCCCTTTGCACCATTATTTGATGCCTCCCCCACCTCATTCCCTCTTCTCAAATACAAACATTCATGAGCTTGCGGACATGAAGGAACGGATCCAAAAAGAATTAATCCGTGGTTTACAGCTTACATCAGGAGGTAAGCTTTTGGATCCAGTGACAGCAACCAATAAACTTCAAGCTTTCCACCAACAAGCTATTGTAGACTTTTCCAAAGGAAACATGaatttgaaaatgaaacatCCTGAAGGTGATATAAAACTGGAAGAAAGCAATCATATAGCGCCAGTAGTAAGTAATGATTTAAAAGAAACTTCTaacaatgtaaacaaaaatgttaccAAAGTACCACCTTTACCAAAGACTAATAGAGAAAGAGATTCCACATCtgttaaaatgattataaaaaatggtGTTTTAATGCCAAAACAGAAGCAGAGAAGGTATCGAACTGAGAGGCCATTTGCATGTGAACATTGTTCTGCACGATTCACTCTTCGCTCTAATATGGAGAGGCACATAAAACAACAACATCCTCAGTTCTGGAGCCAACGTCAGAGAAACAGTTCTGGATCTGTTGGACGCAGAAGTCATCCAGCAGCAGTGCCGACCTCTGTCAACCAGCAGTCTCAAGACTCTAGGAGTTCACGAGATAGTTTCAGTCAAACTTCATCAAAAGGATCTCATTTATCTATAAATGTTGTTTCAAGTGACCCAACAGATTATAGATCCATGCCTTTACTTGAATGGAGGGGTGGTGAAAAGATGCCAAAGATAGAAGAATCCTACACCGAGGAAGTGTTGGATAATATTCACAAAACCAAAGATATATCTAGTGTTGGTGCtatcaacaatttaaataatatagctttTATTTCTGAGGAAGTAAGGTTTGCGATAGCTCAGCAGTTAAAATCAAAACTACACCAGCCTCCTGAAGTACCTCTAGGAGAGGTACCTGGCATAAAATGTGAGGCAAGTGGTGACATGGATGAAGAGGATGAAAATGATGGATTGGTGATTGATGAAGAAAAGGGTGAAGTTGAAGAAGGGAATGAAGAAGGTAACCAGAAACGGGAACAAACCAAAGAACAACAGAATGGCAGTAGGGATGAAGGAGTAGTGGATCTGGCAAGTGTATCAAGACTTTTGGACAATGCCACTACACAGAATCAAGCATTCCAGCAGTATTTCCAGGGAACACAAGATGGTGATGGGGAAGAGGAAGGAACAGAATACGGAAGGGAGGAAGCTAGTGAGGATGATGAAGAAGGACTAGTAGCTGGAAGCAATAGCGAAGGAAACAACTCGGGCAGTGATGAAAACAGatctgAGTCAGATATAAATCCAGGtacagaaaaaaagaagagtgcGTACTCCCTTGCTCCTAATAGAGTTGCGTGCCCATACTGCCTTCGCAAATTTCCGTGGTCCTCATCTTTGCGGCGACATGTCTTGACACATACAGGACAAAAGCCATATAAGTGTCCACATTGTCCACTGCTGTTCACCACAAAGTCAAACTGTGACCGTCATTTGCTCAGAAAACATGGCAGCACATCAGCCACATCTTCTAACAAGAGTAACAATGGTAATGAGACATCTCAAGGAAACGGTGCCCCAACAGGAGCATCAAATCCAAGCTATACGATGAGAAACGTTCCAGAGAGGCCCTTCAAGTGCAACTTCTGTCCAAGCTCTACATTCTCGACGCAGAGCAACTTGAAGAAACACGTCACCACTAAACATAGCAGCCACTCTTGCCCGACAAGTCCTGCAGCAGCTACCACTAGGAACACATGTTCCTCTGGGGATGAGACCTATCAACAAACAACCAGAACAATTGATAGTCGTGGTGCTGGAGATGATAGCCATGATAGTGGAAATGAAGATGTATCAGATGAAAGGTTGACCtatcctaatcccttaaacagAATCACTGAGATTGGTGAAGGGGACATTGAGAGCATGCTTGGTCATCCTGCAATAGATCTGAGAACTAACATTCCTTCACTTGGACCTACACACGATATTGTTGTGCCAAAGACTTTAATAGCGCTCGAAATTCATGGGTCAACCACATCATCGGAGCTACCTTTTAAATGCCACTTGTGTGAAGGGAGTTACGCGGAAAGGCAGGAAGCTTTGGATCATATCCGGGAACATCACCCTACAGAGTTTGATCTACTTGTGACTAAAGGAGCACTGGAAGTATCTACACATGAGGAGAATAATGGGAATAGTCACATCACGTCACAGGAAGAAGGGAATGGAGGTGAAGAAAATCTGGAACAGCTCAGAGGAAAGTTTCCAGACTATGCTAACAGAAAGGTAATGTGTGCATTCTGCCTGCGTCGATTCTGGTCCGCTGAAGATTTGCGGCGACACATGCGCACACACACAGGTGAGCGACCCTTCTCATGTGACATCTGTCGAAGGCGCTTTACTCTGAAACATAGCATGCTGCGCCACCGTAAGAAACATAGCATCGCTGGCATTTCGTACGTGTCTACCAACTCTGAAGATGTTTCCATTGTAAGTGGAGATGAAGACAACATTCAAACACCCCTCACACCTTCTCGCTCACTTTCAGATTCCTCAATTAAAACTCTTGAAAAACATGgcttaaatttaacaaatcatAACAATAACACCATCACCGCCACAAAAAGTTGTACATGGGAGAGCAATAAAAATGAATTGACAGTTTCAGCAGCACAAATTTTAAGTTCAAAGTTGTTATCAGAAAGAAAAGATGAAGCTGTTAACACAGAAGAAGATACTGACTTGATTGGGAATCTGTTGGGGATACAAGACAGGTCGATCATTGACAAAGTTCTCCTGTCCAAGTCTGCTGATGATGCTGCTAAGCTATTGGGTGTAAGAAGTGCAAGTCAGGAGTAG
Protein Sequence: MGNESIHQETSPTDNKIYVRKQESLKLQDTGRKSRGSDIDILEHDNECEKLPNDSTDNKLFEVASKESIALSKKGYEIFKDITEAKNDNYKECDSLDMAEYGSLDCLSPNSESSQMDDSDMKFTCPICDTVLSSQHKFTLHIRSHNNNAESLVYPLASLKNYTCRICGKGLSSSSSLDRHVLVHSGERPFKCTTCGVAFTTNGNMHRHMRTHNPSHAGDNLVLNSKCEYTSYESDGSSDSGGSINNISDNPRKSPHLDTSQAGPAKRRRVDSDGFLIESNNNTNKLSEPLSSVKLHVENGIKRKASDLLTPPDYEGEEIVRRNVNPVTYHQHEFVQQFQCPVCKRIDFASLYVLETHLEERHPDYKATCHQCDLIFKNHRALNLHRFMAQHDNSEEHNIGRVKKSKHINRASSVLGFRDLTFVDFSSEKFPYIAKVMCEQSMHRATSAFHKFQCKKCARAFPCGSALSIHRQACLTSCEKVDFNHPYDPDSFHGDEFPSSDCDTPTDLSSKNKPTQHLRYEKSSDCESEEEQKREDFFAHLDLQTKSVCLSSPLSSEDFRKEDRFENDSYFNSANGNKCEIGKDLADIQSIISVTSAGGLLNDLSKSPQPYGNDITPPDSGVKASDSGTGEEEQQDCFASEFRKMKLKGEFPCRVCTLVFPNLRALKGHNRVHLTASSGLYRCNMCPYSNIDKGILVRHMRTHNGDRPYECALCNYAFTTKANCERHLRNRHSKLSRDDVKNSIIYHPSEDPINDPEIQPKLTTREDVKRSLVFSTNLSTDETNNMDLSNQSFTEEHQKDGLANLHEISNKLSFTDNEPNTIGKPILDDHNEEINHTPTFSNNSLPKTLVPITNISDSNIKQIRPWETHEVATMTHFRDNQVDEVNDIETDSNDDQSDREDNHTAENSNVLVIITKNNFNYSHTNNILTKLPINNQRTLEDPIKTIIPSAITNNLENSYSSDVDMNAPLDLSMDALDLSKKKANEKPPDIVTNINDDFEPQDLSKKSMKHNPEYNNNNKLSKKSLFISSRKSQHYANINKNHSTAQELYNNLNHKISPPPSPGPNTVPKIEMKTGGLYTGSSHLNPIYLNNNGFHFPSQSFPLHHYLMPPPPHSLFSNTNIHELADMKERIQKELIRGLQLTSGGKLLDPVTATNKLQAFHQQAIVDFSKGNMNLKMKHPEGDIKLEESNHIAPVVSNDLKETSNNVNKNVTKVPPLPKTNRERDSTSVKMIIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWSQRQRNSSGSVGRRSHPAAVPTSVNQQSQDSRSSRDSFSQTSSKGSHLSINVVSSDPTDYRSMPLLEWRGGEKMPKIEESYTEEVLDNIHKTKDISSVGAINNLNNIAFISEEVRFAIAQQLKSKLHQPPEVPLGEVPGIKCEASGDMDEEDENDGLVIDEEKGEVEEGNEEGNQKREQTKEQQNGSRDEGVVDLASVSRLLDNATTQNQAFQQYFQGTQDGDGEEEGTEYGREEASEDDEEGLVAGSNSEGNNSGSDENRSESDINPGTEKKKSAYSLAPNRVACPYCLRKFPWSSSLRRHVLTHTGQKPYKCPHCPLLFTTKSNCDRHLLRKHGSTSATSSNKSNNGNETSQGNGAPTGASNPSYTMRNVPERPFKCNFCPSSTFSTQSNLKKHVTTKHSSHSCPTSPAAATTRNTCSSGDETYQQTTRTIDSRGAGDDSHDSGNEDVSDERLTYPNPLNRITEIGEGDIESMLGHPAIDLRTNIPSLGPTHDIVVPKTLIALEIHGSTTSSELPFKCHLCEGSYAERQEALDHIREHHPTEFDLLVTKGALEVSTHEENNGNSHITSQEEGNGGEENLEQLRGKFPDYANRKVMCAFCLRRFWSAEDLRRHMRTHTGERPFSCDICRRRFTLKHSMLRHRKKHSIAGISYVSTNSEDVSIVSGDEDNIQTPLTPSRSLSDSSIKTLEKHGLNLTNHNNNTITATKSCTWESNKNELTVSAAQILSSKLLSERKDEAVNTEEDTDLIGNLLGIQDRSIIDKVLLSKSADDAAKLLGVRSASQE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01445928;
90% Identity: iTF_01445108;
80% Identity: -