Pneb047506.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polia nebulosa
Gene Symbol
-
Assembly
GCA_951329385.1
Location
OX589608.1:21058507-21060876[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 4.8e-06 0.00082 21.5 4.2 1 23 8 31 8 31 0.95
2 20 0.0027 0.46 12.9 0.6 2 23 37 59 35 59 0.92
3 20 2.1e-05 0.0036 19.5 0.3 2 23 68 90 68 90 0.97
4 20 1.6e-05 0.0028 19.9 1.9 2 23 99 121 98 121 0.95
5 20 3.2e-06 0.00055 22.0 1.1 2 23 129 151 129 151 0.97
6 20 1.7e-05 0.003 19.7 2.3 2 23 160 182 159 182 0.95
7 20 8e-07 0.00014 24.0 1.1 1 23 188 211 188 211 0.98
8 20 1.5 2.6e+02 4.2 1.1 2 23 220 241 219 242 0.93
9 20 0.00075 0.13 14.6 1.0 1 23 254 277 254 277 0.97
10 20 0.0043 0.73 12.2 2.0 1 23 302 325 302 325 0.97
11 20 0.52 89 5.7 0.5 2 20 333 351 332 353 0.92
12 20 0.019 3.2 10.2 2.2 2 23 362 384 362 384 0.95
13 20 0.0023 0.39 13.1 5.4 1 23 406 429 406 429 0.97
14 20 0.00011 0.018 17.3 0.4 2 23 436 458 435 458 0.96
15 20 4.2e-05 0.0073 18.5 2.1 2 23 465 487 464 487 0.94
16 20 0.0084 1.4 11.3 2.2 1 23 493 516 493 516 0.97
17 20 0.21 37 6.9 7.1 2 23 524 546 524 546 0.95
18 20 6.8e-05 0.012 17.9 0.7 1 23 553 576 553 576 0.98
19 20 0.023 4 9.9 0.3 1 19 583 601 583 602 0.94
20 20 0.043 7.4 9.1 2.8 5 23 623 642 620 642 0.90

Sequence Information

Coding Sequence
ATGTACCAAAACCAATTAGATTTCGTTTGTGATTACTGCTCGAGGACTTTTACAAGGAAATATAACTTACAGACACATATAGAAAACTGTCATATCAATTCTTCTTGTCACTGTGGCATTTGTGGCCAGAACTTTGGCAGTCCGGCCGGGTTACTGCAACACCTTTCCCGAGGCCACAATAACTATGGCCAGCCATATCCTGAATGTGACCTCTGCGGCAGAATCTTCACACGAAAACAGAACATCACGTCTCATATGATCACAGTACATCTTCAAGGATTAGGATATGAAATTAAGTGTCGTTTATGTGAGAAGACTTTCACTACAGAACGGAATCTGAAGAGACACTTGAACCAGTTACATAATCCCGATGTTGAATACCCAACGTGCAATGATTGTAACAAAGTGTTCAAAGGGAAACACTCGCTGATAGCCCATATACAGACAGTGCACAGCGTGACCGAAAGAGACGCGATTAAGTGCCATCTGTGCGAAAAAGTTTACACTAATAATAGGAACTTGAAGAGGCATGTTGAAATGTTTCACGGTGAAAAGGGTGAGTTCAGATGTGACATCTGCCCGAAAGTGTACACTTCGAATCAGAGTTTACGACGCCACGCGAGAACAAGGCACATTACGGACAACCAGGAACAATTAACTTGCAATTTTTGTATGAAAGTTATCATCGGGCGAGAGAATTTCGAAAGCCATATACAATTCCACCACCAAGACACCGAAATTGATGTTACTAAAGCTGAGTTTGTGTGCGAATCTTGTGACAAGAGCTTCGATGAGGAACCGTGTTTACGGCAGCATGTGAAAACGGAACATTCGTTTAAAACGTTCTATAAGTACTGTAAGAGATCGCTGCTCAAACAGTACGGGATGGATTCGCGAACCATATACAACTGTGAATACTGTCACAGTTCTTTTTTGACTGTCTACGAACTTAAAGACCATATGCGTGTGAATCATGATACTGAGTACTCTCTGTCAACTTGCAACGTTTGCTTCAACAAGTTTTACAGTAAAGAGACTATGTCTGCACATAGAAGTGTCTGTCTCCCGCCTGCCAATGTGAACTCTTGCAGTCACTGCGATAAACTCTTCACTGACGTCTCAAGCTTAGAGTTTCATACGCGAATTTTCCACCCTCAAGCTCAAATAGCAGACTCCAACATCTCTTCTACGTACATCGATGATGAAGCTGTGTCGTATAAATGCGAGCATTGTGATCGCATTTATTACAGCGACAGATCTCTTAAACACCATATTAAGCTTAAACATACAACTGACGAAGAGGTGGAATGCGAATCTTGCGGGAAAATTTGCAGTAACAAGTACTACCTTGCATCACATATTAAAATAGTCCACAATAACGACTCTTGGTCTCGATGTGAGTACTGTGATAAACAGTTTAAATCGAAGAGAAATATCAGAAGACATATTGAATACACTCATTTGGGCATGCAGAGATATAAGTGTATTGAGTGTGAGACATTGTTTAAAGAAAAACGGAGTCTAAGAAAACATGTCAGGACAAAACATCCTAATTCGGCGTCTTTTCCGCAATGCCATATTTGTCACAAACGGTTCGAGTCGGCCAAATCGTGCAAAATCCATCTGAAACTTTTACATTCGTTCAACATGAATACCTACCCGTGTCACCTCTGTTCTGTATCCTTCAGTTCCAACGAGGCTTTGAGTATACACCTACAAACGAAGCACCTTGCCGAAGACCAAATCTACAAATGCGAGGAATGCAACTTAGTGTTCAAAGGGCAAGAGAAATTTGACGCTCACAATGATTGCTGCCACGTCAATTTGGTCCCAACTATCAAACAGAAACTCCTGCCAAGATGCATTCTTTGCATGAAAGATTTTAGCACAAGGAAAACTCTGAAACGACACATAAAGAAATTTCACGACGAATTTGATGTAGATGAGTTAGCTACTTTCGGCTCAAGGCGCAGAACTTTTACTGTGGATTGCGAGGACTGTATCAAAAACTTTAGTGACGATTTTCATTTAAACATCTACCATAAACTCAAACATTTAAAAGATTCGGTGGTGTTCAAGTGTACTTCTTGCTATGAGGCTTACAATGCTTTAGAGTTCGCGATACAGAGGTATAAGGTCTTAAACGCCGATGCCTGTAAGACAAAAATGATCCTAAGCGAGCTCTGTACCACTGAAATGAGTGAAGAAGAGAATGATTTCTCTAACTTTGGAGCGCTACATGATATGTTGCCTGAGAGTACGACTAGTGATTTGAATATAAAGATCGAGCCTCTTGAGTCATTTGAATCTCTGGAGCCTCTAGATGATACGTTTGAGAGGGACGTTAAGATGGAACCAGCTTCGCCGTga
Protein Sequence
MYQNQLDFVCDYCSRTFTRKYNLQTHIENCHINSSCHCGICGQNFGSPAGLLQHLSRGHNNYGQPYPECDLCGRIFTRKQNITSHMITVHLQGLGYEIKCRLCEKTFTTERNLKRHLNQLHNPDVEYPTCNDCNKVFKGKHSLIAHIQTVHSVTERDAIKCHLCEKVYTNNRNLKRHVEMFHGEKGEFRCDICPKVYTSNQSLRRHARTRHITDNQEQLTCNFCMKVIIGRENFESHIQFHHQDTEIDVTKAEFVCESCDKSFDEEPCLRQHVKTEHSFKTFYKYCKRSLLKQYGMDSRTIYNCEYCHSSFLTVYELKDHMRVNHDTEYSLSTCNVCFNKFYSKETMSAHRSVCLPPANVNSCSHCDKLFTDVSSLEFHTRIFHPQAQIADSNISSTYIDDEAVSYKCEHCDRIYYSDRSLKHHIKLKHTTDEEVECESCGKICSNKYYLASHIKIVHNNDSWSRCEYCDKQFKSKRNIRRHIEYTHLGMQRYKCIECETLFKEKRSLRKHVRTKHPNSASFPQCHICHKRFESAKSCKIHLKLLHSFNMNTYPCHLCSVSFSSNEALSIHLQTKHLAEDQIYKCEECNLVFKGQEKFDAHNDCCHVNLVPTIKQKLLPRCILCMKDFSTRKTLKRHIKKFHDEFDVDELATFGSRRRTFTVDCEDCIKNFSDDFHLNIYHKLKHLKDSVVFKCTSCYEAYNALEFAIQRYKVLNADACKTKMILSELCTTEMSEEENDFSNFGALHDMLPESTTSDLNIKIEPLESFESLEPLDDTFERDVKMEPASP