Mdom003426.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musca domestica
Gene Symbol
-
Assembly
GCA_000371365.1
Location
Scaffold18618:82411-85723[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0046 0.23 11.7 5.9 3 23 249 269 247 269 0.96
2 12 0.01 0.5 10.6 2.3 1 23 275 300 275 300 0.93
3 12 0.016 0.81 10.0 0.2 3 23 309 332 307 332 0.92
4 12 0.0003 0.015 15.4 2.2 1 23 343 365 343 365 0.98
5 12 2.8e-06 0.00014 21.8 0.2 1 23 372 394 372 394 0.98
6 12 0.013 0.65 10.2 0.1 1 23 400 422 400 422 0.98
7 12 0.0036 0.18 12.0 2.3 1 23 428 451 428 451 0.98
8 12 0.0096 0.47 10.7 2.4 1 23 457 479 457 479 0.95
9 12 0.00022 0.011 15.8 2.7 2 23 486 507 485 507 0.96
10 12 9.8e-07 4.9e-05 23.2 0.4 1 23 611 634 611 634 0.97
11 12 0.00073 0.036 14.2 2.6 1 23 640 662 640 662 0.97
12 12 2.5e-05 0.0012 18.8 0.4 1 23 668 690 668 690 0.96

Sequence Information

Coding Sequence
ATGGATATTCATTCCATTTGCCGGATTTGCTTGGAGTATTTGCAAAATGACAATGCCTACAATTTGTTCCTGGTCGCTggattgaagaaaaaattgtgtatgtgtACGGCGTTATCGGTGGAGGAGAATGATGGCTTTCCCAAGAATATTTGTGGGGTCTGCTATACCCGTCTCAATGATATGGCAGACTTCCAGAGACTTTGTGCCGATTCGGTGCAAAGATTTCAGGAGCTTGTGGCCAGTCATGTTGTTACGAATTTTCCACCCAACACTTTCGACATGATGGAGGCGGCCCCAGTCACCGAACCAATTGAGGGGGTCCAATTGGGTTTGCCAGACGAGGATGaggacaatttaaattttgatcctttgctAACTAATCATAAAATGGAAATGATTGAAAATGAGGAAGATGTATTTAAGATGCTGGAAAATGTGGACAAGGAGGAACCAGAAGACGATGGAATTGAGACGAAAGTGGAGAAGGAGGAAATAAATGATTCCAACAGTGAGGAGTCCAGTGGCGATGAAAAGGACAgtgattttgaatatcaatttgGAGGCGAAAATTACGATGACGATACTGACAGTGATGATGACAAACCATTGGCAACAAGAGTAAGACACATTAAGAAGGAGTATAAGGAGGAACAAACGGAAGATGATGAGACAAAGGATCCCAAGGTGAAGCCGAAACGTAAACGTATCCCCGCTGCTGAACGTCACTTGCATCGCATCATTGATTGCCACATTTGCCATCAGAAATTCAAGAAAACAAAGAACTATGAGGAGCATATGAAGTTTCACAACGACAAGTTACCCTTCCAGTGCGAAGTGGAGAATTGTAAACGTGGGTTTACCACAGCCTACGGACTGCGTTTGCATGTTGAGCATTGTCACGATGAAACTGTGGAGAAGATACCTTGCACTCAGCCAGGTTGTGATATGAAATTCACTCGTCGTCGCATCTTGAACTGGCACTTGAAGAGGGTCCACAAAATTGCCAAGGAAGACGTACCCAAATCATATCCTTGCAACGAATGTGAAAAGGTATTCAAATGCCCCATGGCCCTGAAGAAACACATGTTCAAGCACACCGGCCAGGAGTTGCCATTCCCCTGTAACATCTGTGGTAAACGTTTCGTCATCAACAGTGCCCTCAAAGACCATCTAATGCGTCATGCTGGCATTAAGAATTATGTATGTCCCTATTGTGGTGTGGGCAAGACCACTCGCCAGGAATGGAATACCCACATAGCCACCCACAACACTGAAAAGAAATTCAAATGCGACCTGTGTCCTCATGCTTCGcacaacaaacaaaatctgCGCATGCACGTACGGGTGGTACACGAGAAGATCAAGGATTATGCTTGCCAATACTGTGGAAAAACATTTGGCAAATCCAATGCCTGTAAGATGCATGAAATGACACACACGGGCGAAAAGAAATGCGAATGTAAAGTTTGCGGCAAACGATTCCTTTATCCAAAGGGCCTAACCAAACATTTGAAGACGCACGAGAAAAGGGTACTACGGGCCATTGAGGTTTATCGTAAGAGACAAGTTGAGTCTGGTGAATTACCTCCCGAACAGGCTGATGCTATTCCAGAACTACCTGATCCCGATAATACACAGGAATCCCATCAGAAGGTTGCAGAAGAAATCCTCAAAGTGTGTGCCGACTCGGTCAACTCCATTCCAAAGGATCCAAGGAGGGTTGAGCGGGTCGACATTGCCGATCTGGCTGGTACTGCTGTCAATCCCATACCTCAATTGGCATTGCCCTCATGGTCGCCTCAAATTAACTTTATGATGAAGGAAGGAAAATACACATGTCCAGATTGCGGCCAAGGTTTCAATGGCTCTGGAAATCTAAGAAGACATCATAAAATTGTCCACCAGGGCGTAAAAGATTTCGCCTGTCGTTTCTGTCCCAAACGATTTGCTAAAGCACAAACTTTAAAACATCACGAAATGACGCACACCGGTGAGAAACCACACGCTTGTGATCAATGTGGCATGCGTTTCATTCAAGTTGTTGCTCTTAAACGTCACATGAAGGTGCATCAGGAACGTCCCACATTTGTTCCTTCGACAGTTTATCAGGCCAAGGAGGAATTGGCAATACAGCAACGTGACAAATACGAGGCCAAACGCAAAGCCCAAGCAGAGCGCGAGGCTATTGCCGAGGAAGCTCGCAAACAATTGGAGGAGCTGAAACGTCAGGAGGAGGAATTGCAACGCAAACAACGAGAAGCACTAGAAAATGTGCCCAAAGCCATTCCAAAAGAACGATTGCCACCCGGCGCTGACATTTCTATTGCCACAAATGTCTTGCCAACCGATCTTGTTGGCAGGCAAGCCGCAGCCGAGGAAGCCCGTAGGCAATTGGAAGATTTGAATCGCCAAGAGGAAGATTTGCGACGTAGACAACGTGaagcatttgaaaatattcccaagGCAATTCCCAAGGAACGTTTACCGCCTGGTGCTGATATATCCGTAGCCACAAATCTATTGCCAGGCGAATATATTCCCAATTCACAAACCCCACATGGCAGCATGGACCATGAAAATCCCTCAACTGCAAACCATGAAAATGTTTATCATCAGGATAATTTAGTTGATATGAATTATAGATAA
Protein Sequence
MDIHSICRICLEYLQNDNAYNLFLVAGLKKKLCMCTALSVEENDGFPKNICGVCYTRLNDMADFQRLCADSVQRFQELVASHVVTNFPPNTFDMMEAAPVTEPIEGVQLGLPDEDEDNLNFDPLLTNHKMEMIENEEDVFKMLENVDKEEPEDDGIETKVEKEEINDSNSEESSGDEKDSDFEYQFGGENYDDDTDSDDDKPLATRVRHIKKEYKEEQTEDDETKDPKVKPKRKRIPAAERHLHRIIDCHICHQKFKKTKNYEEHMKFHNDKLPFQCEVENCKRGFTTAYGLRLHVEHCHDETVEKIPCTQPGCDMKFTRRRILNWHLKRVHKIAKEDVPKSYPCNECEKVFKCPMALKKHMFKHTGQELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHIATHNTEKKFKCDLCPHASHNKQNLRMHVRVVHEKIKDYACQYCGKTFGKSNACKMHEMTHTGEKKCECKVCGKRFLYPKGLTKHLKTHEKRVLRAIEVYRKRQVESGELPPEQADAIPELPDPDNTQESHQKVAEEILKVCADSVNSIPKDPRRVERVDIADLAGTAVNPIPQLALPSWSPQINFMMKEGKYTCPDCGQGFNGSGNLRRHHKIVHQGVKDFACRFCPKRFAKAQTLKHHEMTHTGEKPHACDQCGMRFIQVVALKRHMKVHQERPTFVPSTVYQAKEELAIQQRDKYEAKRKAQAEREAIAEEARKQLEELKRQEEELQRKQREALENVPKAIPKERLPPGADISIATNVLPTDLVGRQAAAEEARRQLEDLNRQEEDLRRRQREAFENIPKAIPKERLPPGADISVATNLLPGEYIPNSQTPHGSMDHENPSTANHENVYHQDNLVDMNYR