Basic Information

Gene Symbol
-
Assembly
GCA_963931995.1
Location
OZ008369.1:19307459-19309921[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0027 0.59 12.9 5.6 3 23 249 269 247 269 0.97
2 12 0.014 2.9 10.7 2.3 1 23 275 300 275 300 0.93
3 12 0.025 5.4 9.9 0.3 3 23 309 332 307 332 0.93
4 12 0.00054 0.12 15.1 2.3 1 23 343 365 343 365 0.98
5 12 3.8e-06 0.00082 21.9 0.2 1 23 372 394 372 394 0.98
6 12 0.018 3.9 10.4 0.1 1 23 400 422 400 422 0.98
7 12 0.011 2.4 11.0 4.8 1 23 428 451 428 451 0.98
8 12 0.013 2.8 10.8 2.4 1 23 457 479 457 479 0.95
9 12 0.0003 0.065 15.9 2.7 2 23 486 507 485 507 0.96
10 12 1.8e-06 0.00039 22.9 0.5 1 23 611 634 611 634 0.97
11 12 0.0067 1.4 11.7 5.8 1 23 640 662 640 662 0.97
12 12 2.6e-05 0.0055 19.3 0.4 1 23 668 690 668 690 0.96

Sequence Information

Coding Sequence
ATGGATATCCATTCCATTTGTCGTATTTGTTTGGAGTATCTGAAAAACGAACATGCCTATGATTTGTTCATGATACCGGGACTGtccaaaaaattgtgtatgtgcaCGGCGCTGTCAGTGGAGCCACAGGATGGTTTCCCCAAAAATATCTGTGGGGTTTGCTATACCCGTCTCAATGACATGTCTGAATTCCAAAAGTTGTGTGCTGATTCGGTACAAAAGTTTCAAGACCTTGTGGCCAAGCATACAGTTGAGTGTGTACCATCGTCTACGTTTGATCTTATGGAGGCGCCATCCACGGAGCCAATTGAAGGAGTCGAATTGGGATTGCCGGACGACGACGATGACCATTTGAATTTTGATCCCCTATTGACAAATCACAAAATGGAAATGATTGAGAACGAGGAGGacgttttcaaaatgttggaaaCAGTTGACAAAGAAGAAGAGGAAGAAGTTGAAGCCAAGGTGGAGAACGAAGGACTAAACAACGATAATGAGTTTACGGAAGAATCCAGCGAAGACGACAGAGACAGTGATGACGATTTTCAGTTTGCCGATGcaaatgatgacgatgatgatagtGACAGCGACGATGATAAACCATTGGCGGTCAGAATGCggaatattaaaaaagaattcaACGATGACGATGAGTTGAGTAGAGATGGTAAGGACCCCAAAATGAAACCGAAACGGAAACGGATACCGGCTGCCGAACGTCACTTGCATCGCATCATAGATTGTCACATCTGTCACCAGAAATTCAAGAAGACTAAAAACTACGAGGAACACATGAAATACCACAACGACAAATTGCCCTTCCAGTGTGAAGTGGAAAATTGCAAACGAGGCTTCACCACCGCGTACGGTTTACGTTTACATGTTGAACACTGTCATGATGAGACCGTGGAAAAGATTCCTTGTACTCAAGATGGTTGTGATATGAAGTTTACGCGGCGTCGCATTCTGAATTGGCACTTGAAGAGGGTGCACAAGATAGCAAAGGAGGATGTGCCCAAGACATATCCTTGTACAGAGTGCGAAAAGGTTTTTAAGTGTCCTATGGCTTTAAAAAAGCATATGTTCAAACACACCGGCCAGGAACTACCATTCCCCTGCAATATATGTGGCAAGCGGTTTGTCATTAACAGTGCCCTTAAGGACCATCTTATGCGACATGCTGGAATTAAAAATTATGTGTGTCCCTACTGCGGCGTGGGCAAGACTACCCGCCAGGAGTGGAATACGCACATTGCCACCCACAATACGGAGAAGAAATTTAAATGTCACCTCTGTCCACATGCATCCCATAACAAACAGAATCTGCGCATGCATGTGCGCGTCGTCCACGAGAAAATTAAGGATTATGCTTGCCAGTATTGCGGAAAAACATTTGGCAAATCGAATGCGTGTAAAATGCATGAAATGACACACACAGGAGAAAAGAGGTGCGAATGCAAAGTATGCGGAAAACGCTTTTTGTACCCCAAGGGACTAACAAAACATctaaagacacacgaaaaacgaGTTTTGAGAGCCATTGAAGTGTACCGAAAGCGACAGGTTGAAATGGGGGAATTGCCGGCAGAGCAGGCTGAACCTATTCCGGAGTTGCCAAACCCTGAAAATACTCAGGAGTCGCACCAGAAAGTTGCTGACGAGATCTTTAAGGTTTGTGCGGACTCTGTGAACTCAATACCGAAAGATCCAAGACGCGTTGAACGCGTGGATATCGCTGACCTGGCTGGAACCGCAGTTAATCCAATACCGCAAATGGCTTTACCTTCATGGTCACCTCAAATAAACTTTATGATGAAGGAAGGAAAATTCACTTGCCCTGATTGTGGCCAAGGCTTCAATGGTTCCGGTAATCTGCGAAGACATCACAAAATTGTTCACCAGGGTGTTAAAGACTTTGCGTGTAGATTCTGTCATAAACGCTTTGCCAAAGCACAAACATTGAAACATCATGAAATGACTCATACTGGAGAGAAACCACATGCGTGTCCTCAGTGTGATATGCGATTCATCCAAGTAGTTGCGTTAAAACGTCACATGAAAGTTCATCAGGAACGAACTACTTTTGTACCCTCCACTGTCTACCAGGCTAAGGAAGAGTTGGCATTGCAAGAACGTAAAAAATACCAAGCGAAACGCATGGCTGAAGAAGAAAGAGAGGCGATTGCGGAGGAAGCACGCAAACAGTTGGAAGAATTAAAGAAGCAGGAGGAAGACCTGCAACGAAGGCAACGGGAAGCTTTGGCTAATCTACCGAAAGCTATTCCTAAGGAACGTTTGCCACCAGGATCAGATATTACAATTGCCACAAATCTCCTGCCAAGCGATTTAATGGCGAATGTTGGTGACCCTGACACATTGGCAGACGAAGCGCCTAACGATGCTTTCAAAACGGAAAGTGAAGAGGAACCCAAGCTTCAATACCCTATGGGTAGTTTTTAA
Protein Sequence
MDIHSICRICLEYLKNEHAYDLFMIPGLSKKLCMCTALSVEPQDGFPKNICGVCYTRLNDMSEFQKLCADSVQKFQDLVAKHTVECVPSSTFDLMEAPSTEPIEGVELGLPDDDDDHLNFDPLLTNHKMEMIENEEDVFKMLETVDKEEEEEVEAKVENEGLNNDNEFTEESSEDDRDSDDDFQFADANDDDDDSDSDDDKPLAVRMRNIKKEFNDDDELSRDGKDPKMKPKRKRIPAAERHLHRIIDCHICHQKFKKTKNYEEHMKYHNDKLPFQCEVENCKRGFTTAYGLRLHVEHCHDETVEKIPCTQDGCDMKFTRRRILNWHLKRVHKIAKEDVPKTYPCTECEKVFKCPMALKKHMFKHTGQELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHIATHNTEKKFKCHLCPHASHNKQNLRMHVRVVHEKIKDYACQYCGKTFGKSNACKMHEMTHTGEKRCECKVCGKRFLYPKGLTKHLKTHEKRVLRAIEVYRKRQVEMGELPAEQAEPIPELPNPENTQESHQKVADEIFKVCADSVNSIPKDPRRVERVDIADLAGTAVNPIPQMALPSWSPQINFMMKEGKFTCPDCGQGFNGSGNLRRHHKIVHQGVKDFACRFCHKRFAKAQTLKHHEMTHTGEKPHACPQCDMRFIQVVALKRHMKVHQERTTFVPSTVYQAKEELALQERKKYQAKRMAEEEREAIAEEARKQLEELKKQEEDLQRRQREALANLPKAIPKERLPPGSDITIATNLLPSDLMANVGDPDTLADEAPNDAFKTESEEEPKLQYPMGSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01019615;
90% Identity
-
80% Identity
-