Mgen005403.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megalopta genalis
Gene Symbol
bab2
Assembly
GCA_011865705.1
Location
NW:1508986-1518661[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.6e-24 2.8e-22 78.1 0.0 3 102 38 133 36 140 0.93

Sequence Information

Coding Sequence
ATGGAGAGTGGAAGTATCTTGAATACCCCAGGTAATTACCCTGGTGGGGATCGTCAACAGTTTTGCGTTTCCTGGAATTCTCATCAGTCGAATATGCACAGTGCGTTTCCTAAATTGTTAAGTTCCGAGCAATTTGTCGATGTCACTTTGGCTTGCGACGGAGGTTCGATAAAGTGTCACAAAGTGGTATTGTCAGCCTGTAGCGATTATTTGGAACGTTTACTGCTAGAAATACCATGCACCCATCCTATTATCTTTTTGAGAGACATGAGAATGTGGGAACTTCAAGCTTTGGTGGAGTTCATGTATCGTGGAGAAGTGTACGTGGAGCAACAGCAGCTGGCAAAGTTAATGCAGGCTGCTGAAGTATTACAGATTCGTGGTCTATCGACCCAAGGAAACGATAACACTTTGAGCGAAACTATTCCTCAACAGTGCGATTCGAATACTCCGTCGGCTGCTCCATCTACTACCACGCAGCAGGATGGAATCAATTTTAAAACGGAGGAAACTCATTCGGACGACGGAACATCGAATGCTAATTTTCTGGAGGCTACGTCGATCGCCGCATCTAGTACAGCCAGTGCGCCATCGCACACTAGCACTCCGGTGTCGCAGAACCCAAATTCGTCGAATTTTATGAACATGGAGCACAGCGAAGCGCTCCAACATTTGGAAAAAGCGCTCAGCGCTTGCGAAGCGACTCTAACCGAGACCCAGGGAATGGTAAAGATGGAACCGGACGAGCAATTTACTCAGCAACAGGATGTAAAACCGTACTCGATCAGTATGGTACCGAGCAGTAATTGTAATCCTAGTAGCCCGTTTCCTGCAATCGAAGGTTACCAGAGACGACAAAGACGTTCGGAGGAAGAATTGAAACAAGCTTCGGACATGGTGGCACGTGGTATGACGTTTCAAGTTGCTtcggaaaaatataaaattccgaTAAGTACGATTCGATTCTACATGGTTCGAAAAGGTATATTGCAAAGGCGAAAACGCGGTCGTGGTTCAAGCAATCTTGGCATGAACAGTCAGCCAGGAAGCCCGGCAAGTCCGCCGTATCATATGATGAATTATCGTTTGCCAGAGAGCCTAAACTCCAGCCTACCGTAG
Protein Sequence
MESGSILNTPGNYPGGDRQQFCVSWNSHQSNMHSAFPKLLSSEQFVDVTLACDGGSIKCHKVVLSACSDYLERLLLEIPCTHPIIFLRDMRMWELQALVEFMYRGEVYVEQQQLAKLMQAAEVLQIRGLSTQGNDNTLSETIPQQCDSNTPSAAPSTTTQQDGINFKTEETHSDDGTSNANFLEATSIAASSTASAPSHTSTPVSQNPNSSNFMNMEHSEALQHLEKALSACEATLTETQGMVKMEPDEQFTQQQDVKPYSISMVPSSNCNPSSPFPAIEGYQRRQRRSEEELKQASDMVARGMTFQVASEKYKIPISTIRFYMVRKGILQRRKRGRGSSNLGMNSQPGSPASPPYHMMNYRLPESLNSSLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00393525;
90% Identity
iTF_00184034; iTF_00965963; iTF_00183377; iTF_01539709; iTF_01070955; iTF_01071105; iTF_01424479; iTF_00863369; iTF_00864743; iTF_00864076; iTF_00861997; iTF_00865430; iTF_00860503; iTF_00861276; iTF_00141163; iTF_00142558; iTF_00141311; iTF_00142400; iTF_01066177; iTF_01070466; iTF_01067043; iTF_01067716; iTF_01065676; iTF_01069773; iTF_01068399; iTF_01069077; iTF_01066365; iTF_00215810; iTF_00684260; iTF_00684877; iTF_00684090; iTF_00140690; iTF_00141926; iTF_00230133; iTF_00676124; iTF_00085516; iTF_00087304; iTF_00088944; iTF_00088152; iTF_00086425; iTF_00084670; iTF_01420364; iTF_01419095; iTF_01419737; iTF_00226018; iTF_00873892; iTF_00231910; iTF_00760911; iTF_00214321; iTF_00233331; iTF_00232084; iTF_00761077; iTF_00214491; iTF_00118112; iTF_00229453; iTF_01418446; iTF_00216501; iTF_00221842; iTF_00222005; iTF_00232534; iTF_00232700; iTF_00225341; iTF_01122990; iTF_01122549; iTF_01123157; iTF_00963939; iTF_00963781; iTF_00963291; iTF_00962607; iTF_00964575; iTF_00961926; iTF_00866799; iTF_00866113; iTF_00862679; iTF_00762652; iTF_01417807; iTF_00983690; iTF_00982390; iTF_00983066; iTF_00223298; iTF_00218531; iTF_00222628; iTF_00228074; iTF_00228779; iTF_00226700; iTF_00220685; iTF_00223983; iTF_00224656; iTF_00219218; iTF_00227378; iTF_00221367; iTF_00215128; iTF_00217176; iTF_00217849; iTF_00230619; iTF_00231420; iTF_00219901; iTF_00230784; iTF_00306384; iTF_00763157; iTF_00763329; iTF_00734039; iTF_00733890; iTF_01169275; iTF_00360316; iTF_00361007; iTF_00625600; iTF_00625420; iTF_00024710;
80% Identity
iTF_00965963;