Mgen006945.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megalopta genalis
Gene Symbol
Lrrfip2
Assembly
GCA_011865705.1
Location
NW:2892284-2899045[+]

Transcription Factor Domain

TF Family
LRRFIP
Domain
LRRFIP domain
PFAM
PF09738
TF Group
Unclassified Structure
Description
LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 4.8e-108 4.5e-104 347.0 37.9 1 300 58 379 58 379 0.95
2 3 0.0048 45 2.2 4.2 121 172 378 429 376 438 0.91
3 3 0.075 7e+02 -1.7 5.7 195 238 411 453 400 454 0.56

Sequence Information

Coding Sequence
ATGGTCATCGTGCTTGAGCCAAACTCATCCGATTTCTCTGATCCGATTGTATTTATAGTGTCATCTGGTTTATTTTCGCATTCGTGCAGCTTCTTTGGAAAGAAGGATGCTGCTATCCGCTGGCTGACAGCGTTTCCGTGTATCCGATGGATTTTCCATACATACTTTCAGGCAGAAGCTAGATTAGCTGCAAAGAGACATGCAAGAGCTGAAGCAAGAGAAATACGAATGCGTGAATTAGAAAGACTACAAAAAGAGGCGGAGGAGAATGCGGATAGAGTTTATGACATGTGTTCGGCCGACGTAAATAGGACAATGAGAGTAACTCCAGACTCTGTAAGGACGACGCGCCTCcttacaaattccaacaattttcaatCCAGTCGTAGGTCTTCCGAAGACTCTTTAGAAGATGCAGGTCTAAGTAGAGATCTCAGGTTAGAACTAAAGGAGTTTGAAGAGAAATTTAGGAAGGCTATGATAGCCAATGCTCAGTTAGACAATGAAAAGTCTTCTTACTCCTATCAAGTTGATTTATTGAAAGACAAGTTGGAAGAATTAGAGGAAACAGTTGCACAACTTCGTAGAGAACTTAGAGAGAAGAATCGAGAATCTGAACAGTTGAAAAGAATCAGTCAAAGATTGAAAGAAGATTTAGATATATGTCATGCACAATTAATAGAAAGAGACGCGCTTATACAAGAGAACGGTTTAGTTATTCTTGACGATGAGGAGAGTGAAAACGAAGATAACGATATTGAAAACGGTCCGCGTCCAAGACGAAGAGTACTAGTCAGTACAGAAGCAGCAGAGTTGTTGCAAAATGCTGGGAAAGGTTCATTAGATGTCCGGCTGCGAAAATTCGCTTCTGAAAAAAAGGAATTACAAGATGAAATTCGGCATTTAAGATTGGAATTAGAAGAATCCAGGAATCGCATTAGGTCCGAGAAATCACCTGGTTCAGTATTAGGTAAGCGTTCACTTCGACATGTGAcattttatttcctttcaaCGTTGTGGCATTTGTTGCGTACGACAGGTTGTTTGTCAGATTCCGAGGATGTGCAACGAGAAGCGAATAAATTGTTAGCCGATTACAAGTTCAAGTTACAGAAGGCAGAGCAAGACATGTCGACTTTACAAGCCACCGTTGCCAGGCTAGAGAGCCAAGTAATACGTTACAAGTCAGCCGCAGAAGCGTCAGAGAAGGCGGAAGACGaattaaaagttgaaaaacgaaaaCTTCAAAGAGAAgTCAGAGAGACCCAAGGCCGCGTCGAAGAATTAGAGACTGCGAATTCACATTTACAAAGGCGACTAGATAAACTTAAAAACGCAAAATCAGCTCTGTTGAAAGAACTTTGA
Protein Sequence
MVIVLEPNSSDFSDPIVFIVSSGLFSHSCSFFGKKDAAIRWLTAFPCIRWIFHTYFQAEARLAAKRHARAEAREIRMRELERLQKEAEENADRVYDMCSADVNRTMRVTPDSVRTTRLLTNSNNFQSSRRSSEDSLEDAGLSRDLRLELKEFEEKFRKAMIANAQLDNEKSSYSYQVDLLKDKLEELEETVAQLRRELREKNRESEQLKRISQRLKEDLDICHAQLIERDALIQENGLVILDDEESENEDNDIENGPRPRRRVLVSTEAAELLQNAGKGSLDVRLRKFASEKKELQDEIRHLRLELEESRNRIRSEKSPGSVLGKRSLRHVTFYFLSTLWHLLRTTGCLSDSEDVQREANKLLADYKFKLQKAEQDMSTLQATVARLESQVIRYKSAAEASEKAEDELKVEKRKLQREVRETQGRVEELETANSHLQRRLDKLKNAKSALLKEL