Basic Information

Insect: Macrophya annulata
Gene Symbol: ZFX
Assembly: GCA_963924015.1
Location: OZ001260.1:7235829-7240618[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2 2e+02 3.4 0.1 3 23 14 34 13 34 0.94

2 15 0.17 18 6.7 2.1 1 23 882 905 882 905 0.94

3 15 0.00026 0.027 15.5 0.6 2 23 983 1005 982 1005 0.96

4 15 0.017 1.8 9.8 0.3 2 23 1018 1039 1018 1039 0.98

5 15 2.1e-05 0.0022 19.0 2.3 2 23 1042 1063 1041 1063 0.97

6 15 0.015 1.5 10.0 0.3 1 23 1069 1091 1069 1091 0.95

7 15 2.9e-05 0.003 18.5 4.5 2 23 1098 1119 1097 1120 0.95

8 15 0.13 14 7.1 3.7 5 23 1133 1151 1132 1151 0.97

9 15 2.6e-05 0.0027 18.7 1.5 3 23 1158 1179 1157 1179 0.97

10 15 0.012 1.3 10.3 0.3 2 23 1195 1215 1194 1215 0.97

11 15 8e-05 0.0083 17.2 0.7 1 20 1221 1240 1221 1243 0.92

12 15 9.9e-05 0.01 16.9 2.7 1 23 1251 1273 1251 1273 0.99

13 15 0.0028 0.29 12.3 3.2 1 23 1279 1301 1279 1301 0.97

14 15 2.8e-06 0.00029 21.7 3.9 1 23 1307 1329 1307 1329 0.99

15 15 0.00036 0.037 15.1 7.2 1 23 1335 1357 1335 1358 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2	2e+02	3.4	0.1	3	23	14	34	13	34	0.94
2	15	0.17	18	6.7	2.1	1	23	882	905	882	905	0.94
3	15	0.00026	0.027	15.5	0.6	2	23	983	1005	982	1005	0.96
4	15	0.017	1.8	9.8	0.3	2	23	1018	1039	1018	1039	0.98
5	15	2.1e-05	0.0022	19.0	2.3	2	23	1042	1063	1041	1063	0.97
6	15	0.015	1.5	10.0	0.3	1	23	1069	1091	1069	1091	0.95
7	15	2.9e-05	0.003	18.5	4.5	2	23	1098	1119	1097	1120	0.95
8	15	0.13	14	7.1	3.7	5	23	1133	1151	1132	1151	0.97
9	15	2.6e-05	0.0027	18.7	1.5	3	23	1158	1179	1157	1179	0.97
10	15	0.012	1.3	10.3	0.3	2	23	1195	1215	1194	1215	0.97
11	15	8e-05	0.0083	17.2	0.7	1	20	1221	1240	1221	1243	0.92
12	15	9.9e-05	0.01	16.9	2.7	1	23	1251	1273	1251	1273	0.99
13	15	0.0028	0.29	12.3	3.2	1	23	1279	1301	1279	1301	0.97
14	15	2.8e-06	0.00029	21.7	3.9	1	23	1307	1329	1307	1329	0.99
15	15	0.00036	0.037	15.1	7.2	1	23	1335	1357	1335	1358	0.96

Sequence Information

Coding Sequence: ATGGAACTTGGAACCAGCATGACTGCAGGGGCAGTTGCCTGCCCCGTTTGTACCTTATATTTAAGGGAAGGTATAAGCCTGCAAAAGCACTTGGACACTCATCCCAAAGAGCAGGTAATAGAAGCTTTAATAAAAGCTAGTTCATCTCCGGCTCAACCACAACTAAACCTTTCACAACCGGCTCAAAATCCTTTACAAACAGCTCCAAATCCGGTTGCTTCACAGTCTCCCTATCCCGTTGGACCTGTGTTCGAATGTCCTCCTGTAGCGTCAATGATGTCTCCTCAATTTGCCTCGTTTAGTTATCAACAATTTGTTAATAACGGAACAATGATGATACCCCAATACGCCATGGCCCCACAGGCTAATCAGATGATGCAAATGTTGTACAATCCTTACGGAATgtatcaacaacaacaaatacCAGCGGTTCAAATGATCGCCCCTATATCCAACGTGCCAACAGCTCAAAGATCTAGACCCATGGTTTCTGTGGGAAGCGAAACTAACACCAGGAATAATATTGCTTCTTCTTTGAGCGGTGTTGATATCGAACCTAAGCAAATTTTACCGGAAATAGAGGCCGAGGTGGAGCCAGAACAGCTCTTACCTGAAGTTGAAATTGAGTCGGTGACGAGCACAAATCAACACGAGAATAATCACGTGGATAGAAATCAATCTGAACATCAAACACAACAGATACAGCAGGAATCTATAAATCAAGAGAATGGCGGCAGTAGAATGGAGTATCAAAATATCGTGCAAAATTTATCAGCTAATGAAGATGGGGTTGTTGTTCACGGTGATAAGACTGAGAATGAAAGCGTACTACCAGATATTGAACAACCAGAATCTACAAGCCAGACACAACATGTTGTACCCATTCAGCATGAACATACGCAAACTCAACAGGGTGAAGAGTTTGGGCATGGATTTGGGGGCAGCATTGGAAAGGAACGAGCCACTCAATCTCGGATTATTGATGACGAGGAGGAAGTAGAAGAGGATAATAAAGTGGATagcgaaaatgaaaatcttcaaaatacCGTTTCTAATGCAGATGTTAATATGGTTGTTGAGAGACCAAAGAATTCTAATGCTCAACCTGAGGTGGAGCAACTCGAACGTCTTTTGATAACTATTATGGAGACGgaatttaataacaaaaagggcgaagaagaggaaagagaCAAGGAACGATGCGATGTGGAAATTTCTGCTGGTGATAGAGAAACTAGTGTTATTCAAGAGACTTCGACGACAAGTTTGGACTTCCAGAAAAACAGTCTTAAGGTTTTCGAGACTGAAGAAATCAGGGAATCATTCGATAGTAACAAAGACATTGATGACGAAGAACGAAAATTAGAAGAATTAGAAGCGGGTGAATGTTATGAACAAGAAACTGATGCCCAAtttgtatatagttataaaaatagCTTATCTGCTCCGGCCTCGCCAGCTACTCAGAGAATTTTAAATCGGCAAAGAACTTATTCGGTTCGTTCTGAAATGGGATCCAATGAAAACCTGAGCTCTTACCCAGTTGGTTTTGAGGCAACTACGCTGTTggacgaagacgaagaagatgtGAATGAAAAACGTGAGACTGTTGATAATTTCGACGAGGAAGATATGGAGATTGAAGAGATCACAAGTCCACATACACCGTTTACAAAACATAATGAAAATTCTGAGTGCGTCAGATCTCATACACCATTATCAACCATTAGTGGAATCTCTGGGCTTAGAGTAAGGACTGATCTCAGCAAACCATGTTCTCCTGCATCAACTCATTCCTTTCATCACATGGACACAAACAGCCTTTGCGCAGAAGATGATGGGGAGGAGCTAGTAGATCCAGATACTGAAAAAGACCCTATAGATTGTTCCCAGTTACAGAGAGAAGCGGAGTTGATTGAAAACCTGAAGAATATATCACATAAATTACAGCCCAATCACGTTTATCATCAGTCTGTGATCACAGAAAATCTTGCCTCATTTTCTATCAGTCATCATTCTCAAAAACCTATGACTATTCACGATACTTACGAATCCTCGAATTGCCAACACAATGCTGACAATCTTTTGGACCTATCCGAACCATCTGAACCAACTACTAGTACagattcaaagaattttcaatctgTTAAATCAATTCTACAAAAACCGACTACTGAATTGTTGAATATCAACGAAGATGCACATCCTGGGCCCATGAATGTACTCGAATTTGATGGACTACAGATTCTTGTTCCCAGTACATTCATAAGCGAATCTTCACAGAAAGCGGTCAGTGCTACTAGCCGACAATCAATGGCAAGTAGTGAGGGCGGGGCAGAGGCCGATGAGGAAATCAAAAGCGTTAATATGCGGGCAGACGAGATCATGCCTCCAAGGGGCGAATTGTCAGAGCAGGAGAGTAACGGATGCCATGAACCTTCCGCATGGCAGcAGTTGTATATGGGTCAAGAATCATCCCGGATGTCTACATCTTACGATTTAATGGCTCGTGAAAGTTGGGAGGAATCTGAAGGATCGGACAACGAAATAGGAGGCCCTCTTTTGGACAGCCGTTCATTAGCCACACACTTCACTTCAAGCTTATTTCTTGATCGCGATAGAAAGACTCCTACAAAGCGATCGTTCAAATGTCCTCATTGTTCAGAAATCTTTGATTGTCCAAAGGAACGCAGAGTGCATATGGGCACTGTCCACAAAGAAGCAGGTCCAAGCAGCAGTAGGGATCCTATGGAACAGCCCGAAGTAAAAGACATAAAATTACTAGAAGGACGAATGAACGTATTCGACGACCTCTTTGTTCCCGGTTTGCACGTCCAACAGCCTCTTTTGCATCAATTACAGCCAGCACATCATCCCCCTGATCTGACAAAGTTGGAAGTTGAtagaaagattgaaaatttaattgttccAACGTCGATTGAAATCTCTTGTCCAATTTGCGGACAGTTATTTAGTAGCGATAAATCTCTTCAGATACATCATAGGAGGGTACATGTTTCCGAGAGTAATAAACGTGTCAGGGAAAGCGCCAAGTGTCAAACTTGTAACGAAGAATTTCCTTCTGTTGTTTTGTATAATACACACTTGAAGATACATCCCTTGGAATGTGGTCAATGCGGTAAATACttttacagaaaacaaaactttAAATTGCACATGAAACGACACCTTGGAATAAAGCCTTTTCCTTGCACTGTATGCGACAAAGCTTTTCTTACCAAACAAAAACTGGACGAACATACAAATGGACATACTGGTAACGCCCCAGTCAAGTGTAACTTATGTAACGAGACGTTTAGACGTTATTCTAACTTGACTCAACACAAAAATCGACATCATCTAAACATTAAGAAGAAATTAAAGGACTACATTTGTCATTGCGGCGAAGTATTTCATACTAAGAAGAAACTTGCTTGGCATAAAGAAACTCACGATGAAAAACCTAAGGCTTGCACTTATTGTAATGAGAGGTTTATTCACATGGCCAGTTTAACTAGACACATGCGAAGAGCTCATAATAGAAGATTTGTTCCCGACGCTCaaagagaaaacgaaaatgttGAGTGTCCAATTTgcaaatgtatttatttacgcTCGTCGTTGGCTGTTCATATGCGAGTTCACAATGGTGAGAGACCCTACGAGTGTCAAGTTTGTTCAAAGGCCTTCAGCACAAAATGGAATCTACAGCTGCACAAATGGACTCATGCAGCGCGTAGTACGAAACCTTTTAAATGCAATCAATGTAGCGCTGCATTTTATCGTCACAGTGACTACACAGCTCATATGAATTCTCATCGGAACGTTCGGCCTTACACGTGTAACTACTGCGGGGCACAATTCATTCGTAAATACAACTGTTTGCGGCACGTCAAAGAACATGAAGAGAATAAATCCTACACATGCGATATTTGCAACAAAACATTTCATCGATCGTATTACCTTAAAGAACATTTGCGAGTACATTCGGGAGCCAGACCCTACACTTGTCATATCTGTGGCAAGTCTAGTAGTACCAAGTCAAATCATAATAAACACGTAAGAATTCATCATGCGAGAGAACCTGTAAATACAGAAAACTAA
Protein Sequence: MELGTSMTAGAVACPVCTLYLREGISLQKHLDTHPKEQVIEALIKASSSPAQPQLNLSQPAQNPLQTAPNPVASQSPYPVGPVFECPPVASMMSPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPAVQMIAPISNVPTAQRSRPMVSVGSETNTRNNIASSLSGVDIEPKQILPEIEAEVEPEQLLPEVEIESVTSTNQHENNHVDRNQSEHQTQQIQQESINQENGGSRMEYQNIVQNLSANEDGVVVHGDKTENESVLPDIEQPESTSQTQHVVPIQHEHTQTQQGEEFGHGFGGSIGKERATQSRIIDDEEEVEEDNKVDSENENLQNTVSNADVNMVVERPKNSNAQPEVEQLERLLITIMETEFNNKKGEEEERDKERCDVEISAGDRETSVIQETSTTSLDFQKNSLKVFETEEIRESFDSNKDIDDEERKLEELEAGECYEQETDAQFVYSYKNSLSAPASPATQRILNRQRTYSVRSEMGSNENLSSYPVGFEATTLLDEDEEDVNEKRETVDNFDEEDMEIEEITSPHTPFTKHNENSECVRSHTPLSTISGISGLRVRTDLSKPCSPASTHSFHHMDTNSLCAEDDGEELVDPDTEKDPIDCSQLQREAELIENLKNISHKLQPNHVYHQSVITENLASFSISHHSQKPMTIHDTYESSNCQHNADNLLDLSEPSEPTTSTDSKNFQSVKSILQKPTTELLNINEDAHPGPMNVLEFDGLQILVPSTFISESSQKAVSATSRQSMASSEGGAEADEEIKSVNMRADEIMPPRGELSEQESNGCHEPSAWQQLYMGQESSRMSTSYDLMARESWEESEGSDNEIGGPLLDSRSLATHFTSSLFLDRDRKTPTKRSFKCPHCSEIFDCPKERRVHMGTVHKEAGPSSSRDPMEQPEVKDIKLLEGRMNVFDDLFVPGLHVQQPLLHQLQPAHHPPDLTKLEVDRKIENLIVPTSIEISCPICGQLFSSDKSLQIHHRRVHVSESNKRVRESAKCQTCNEEFPSVVLYNTHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKSYTCDICNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00938966; iTF_01413635; iTF_01200391; iTF_01048397; iTF_00718830; iTF_00719645; iTF_00060559; iTF_01303669; iTF_01414425; iTF_01412629; iTF_01411770; iTF_00174505; iTF_01049124; iTF_00175916; iTF_00175254;
90% Identity: iTF_01413635;
80% Identity: -