Basic Information

Insect: Macrophya alboannulata
Gene Symbol: ZFX
Assembly: GCA_949628255.1
Location: OX451210.1:15633558-15638378[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.9 2.4e+02 3.3 0.1 3 23 14 34 13 34 0.94

2 15 1.3 1.6e+02 3.9 2.6 1 23 889 912 889 912 0.83

3 15 0.00026 0.032 15.5 0.6 2 23 990 1012 989 1012 0.96

4 15 0.017 2.1 9.8 0.3 2 23 1025 1046 1025 1046 0.98

5 15 2.1e-05 0.0026 19.0 2.3 2 23 1049 1070 1048 1070 0.97

6 15 0.015 1.8 10.0 0.3 1 23 1076 1098 1076 1098 0.95

7 15 2.9e-05 0.0036 18.5 4.5 2 23 1105 1126 1104 1127 0.95

8 15 0.13 16 7.1 3.7 5 23 1140 1158 1139 1158 0.97

9 15 2.6e-05 0.0033 18.7 1.5 3 23 1165 1186 1164 1186 0.97

10 15 0.012 1.5 10.3 0.3 2 23 1202 1222 1201 1222 0.97

11 15 7.8e-05 0.0099 17.2 0.7 1 20 1228 1247 1228 1250 0.92

12 15 9.7e-05 0.012 16.9 2.7 1 23 1258 1280 1258 1280 0.99

13 15 0.0027 0.34 12.3 3.2 1 23 1286 1308 1286 1308 0.97

14 15 2.8e-06 0.00035 21.7 3.9 1 23 1314 1336 1314 1336 0.99

15 15 0.00035 0.045 15.1 7.2 1 23 1342 1364 1342 1365 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.9	2.4e+02	3.3	0.1	3	23	14	34	13	34	0.94
2	15	1.3	1.6e+02	3.9	2.6	1	23	889	912	889	912	0.83
3	15	0.00026	0.032	15.5	0.6	2	23	990	1012	989	1012	0.96
4	15	0.017	2.1	9.8	0.3	2	23	1025	1046	1025	1046	0.98
5	15	2.1e-05	0.0026	19.0	2.3	2	23	1049	1070	1048	1070	0.97
6	15	0.015	1.8	10.0	0.3	1	23	1076	1098	1076	1098	0.95
7	15	2.9e-05	0.0036	18.5	4.5	2	23	1105	1126	1104	1127	0.95
8	15	0.13	16	7.1	3.7	5	23	1140	1158	1139	1158	0.97
9	15	2.6e-05	0.0033	18.7	1.5	3	23	1165	1186	1164	1186	0.97
10	15	0.012	1.5	10.3	0.3	2	23	1202	1222	1201	1222	0.97
11	15	7.8e-05	0.0099	17.2	0.7	1	20	1228	1247	1228	1250	0.92
12	15	9.7e-05	0.012	16.9	2.7	1	23	1258	1280	1258	1280	0.99
13	15	0.0027	0.34	12.3	3.2	1	23	1286	1308	1286	1308	0.97
14	15	2.8e-06	0.00035	21.7	3.9	1	23	1314	1336	1314	1336	0.99
15	15	0.00035	0.045	15.1	7.2	1	23	1342	1364	1342	1365	0.96

Sequence Information

Coding Sequence: ATGGAACTTGGAACCAGCATGACTGCAGGGGCAGTTGCCTGCCCCGTTTGTACCCTATATTTACGAGAAGGTATAAGCCTGCAAAAGCATTTGGACACTCATCCCAAAGAGCAGGTAATAGAAGCTTTAATAAAAGCTAGTTCATCTCCGGCTCAACCACAACTAAACCTTTCACAACCGGCTCAAAATCCTTTACAAACACCTCCAAATCCGGTTGCTTCACAGTCTCCCTATCCCGTTGGACCTGTGTTCGAATGTCCTCCTGTAGCGTCAATGATGTCTCCTCAATTTGCCTCGTTTAGCTATCAACAATTTGTTAATAACGGAACGATGATGATACCCCAATATGCCATGGCACCACAGGCTAATCAGATGATGCAAATGTTGTACAATCCTTACGGAATgtatcaacaacaacaaatacCAGCTGTTCAAATGATCGCCCCAATATCCAACGTGCCAACAGCTCAAAGATCTAGACCCATGGTTTCTGTCGGAAGCGAAACTAACACCAGAAATAATATTGCTTCATCTTTAAGCGGTGTTGATATTGAACCTAAGCAAATTTTACCTGAAATAGAGGCCGAAGTTGAGCCGGAACAGCTCTTACCTGAAGTCGAAATTGAGTCGGTGACGGGCACAAATCAACACGAGAGTAATCACGCGGATAGAAATCAATCTGAACATCAAACACAACAGATACAGCAGGAATCTATAAATCAAGAGAATGGCGGCGGTAGAATGGAGTATCAAAACATCGTGCAAAATTTAACAGTTAATGAAGATGGGGTTGTTGTTCACGATGATAAGACTGAGAATGAAAGCGTACTACCAGATATTGAACAACCGGAATCGATAAGCCAGACACAACATGTTGTACCCATTCAGCATGAACATACACAAACACAACAGGGAGAAGAGTTTGGGCATGGATTTGGGGCTAGCATTGGAAAGGAACGAGACATTCAATCTCGGACTGTTGATTTTGAAGAGGAAGTAGAAGAGGATAATAAAGTGGATGGTGagaatgaaaatcttcaaaatacCGTTTCTCATGCAGATATAAACATGGTTGTTGAGAGACCAAAGAATTCTAACGATCAACCTGAGGTGGAGCAACTCGAACGTCTTTTGATAACTATTATGGAGACGGAATTTAATGTCAATCGTCCGAAAAGTAAAGACAAGAAGGGTCAAGAGGACGTAAGAGACGAGGAACGATGCGATATGGAAACTTCTGCCGCTGATAGAGAAACTAGCGTTATTCAAGAGACTTCAACGACAAGTTTGGACTTCCAGAGAAACAGTCTTAAGGTTTTTGAGACTGGAGAGATCAGAGAATCATTTAATAGTAACAAAGACATCGATGAGGAAGAAGGAAAATCGGAAGAATTAGAAGCGGGTGAATGTTATGAACAAGAAACTGATGCCcaatttgtatataattataaaaatagcTTATCTGCTCCGGCTTCACCAGCTACTCAGAGAATTTTAAATCGGCAAAGGACTTATTCGGTTCGTTCTGAAATGGGATCTAATGAAAACCTGAGCTCTTACCCAGTTGGTTTTGAGGCAACTACGCTGTTAgacgaagatgaagaagacgTGAATGAAAAACGTGAGACAGTTGATAATTTCGACGAGGAAGACATGGAGATTGAAGAAATCACAAGTCCACATACTCCATTTACAAAACATAATGAAAACTCTGAGTGTGTCAGATCTCATACACCATTGTCAACCATTAGTGGAATCTCTGGGCTTAGAGTAAGGACTGATCTCAGCAAACCGTGTTCACCTGCATCAGCTCATTCCTTTCATCACATGGACACAAACAGCCTTTGCGCAGAAGATGATGGGGAGGAGCTAGTAGACCCAGATACTGAAAAAGATCCTATAGATTGTTCTCAGCTACAGAGAGAAGCGGAGTTGATTGAAAACCTGAAGAATATATCACATAAATTACAGCCTAATCACGTTTATCATCAGTCTGTTATCACAGAAAATCTTGCCTCGTTTTCTATCAGTCACCATTCTCAAAAACCTATGACTATTCACGATACTTACGAATCTACGAATTGCCAACACAATGGTGACAATCTTTTGGACCTATCTGAACCGTCTGAACCAACTACTAGCACAgattcaaagaattttcaatctGTTAAATCAATTCTACAAAAACCGACTACTGAATTGTTAAATATCAACGAAGACGCACATCCTGGGCCCATGAATGTACTCGAATTTGATGGACTACAGATTCTTGTTCCTAGTACATTCATAAGCGAATCTTCACAGAAAGCGGTCAGTGCTACGAGCCGACAATCAATGGCAAGCAGCGAGGGCGGGGCAGAGGCCGATGAGGAAATCAAAAGCGTTAATATGCGGGCGGACGAGATCATGCCTCCAAGGGGCGAATTGTCAGAGCAGGAGAGTAATGGGTGCCACGAACCTTCTGCCTGGCAGCAGTTGTACATGGGTCAAGAATCATCCCGGATGTCTACATCTTACGATTTAATGGCTCGTGAGAGCTGGGAGGAATCTGAAGGATCGGATAACGAGATAGGTGGCCCTCTTTTGGACAGTCGTTCATTGGCCACACACTTCACTTCAAGCTTATTTCTTGACCGCGATAGAAAGACTCCTACAAAGCGATCGTTCAAGTGTCCTCATTGTTCAGAAATCTTTGATTGTCCGAAGGAACGCAGGGTGCATACGGGCACTGTCCACAAAGAAGCAGGACCAAGCAGCAGTAGGGATCCTATGGAACAGCCGGAAgtaaaagatataaaattattggaaGGACGAATGAACGTGTTCGATGACCTCTTTGTTCCCGGTCTGCATGTCCAACAGCCTCTTTTACATCAATTACAGCCAGCACATCATCCCCCTGATCTGACAAAGTTGGAAGTTGATAggaagattgaaaatttaattgttcCGACATCGATTGAAATCTCTTGTCCAATTTGCGGACAGTTATTTAGTAGCGATAAGTCTCTTCAGATACATCATAGGAGGGTACATATTTCCGAGAGTAATAAACGCGTCAGGGAGAGCGCCAAGTGTCAAACTTGTAACGAAGAATTTCCTTCGGTTGTTTTATATAATACACACTTGAAGATTCATCCCTTGGAATGTGGTCAATGCGGTAAATACTTTTACAGAAAACAAAACTTTAAATTGCACATGAAACGACACCTTGGAATAAAGCCTTTTCCTTGCACTGTATGCGACAAAGCTTTTCTTACCAAACAAAAACTGGACGAGCATACAAATGGACACACTGGTAACGCCCCAGTCAAGTGTAACTTATGTAACGAGACGTTCAGACGTTATTCTAACTTGACTCAACACAAAAATCGACATCATCTAAACATTAAGAAGAAATTAAAGGACTACATTTGTCATTGCGGTGAAGTATTTCATACTAAGAAGAAACTTGCTTGGCATAAAGAAACTCACGATGAAAAACCTAAGGCTTGCACTTATTGTAATGAGAGGTTTATTCACATGGCCAGTTTAACTAGACACATGCGAAGAGCTCATAATAGAAGATTTGTTCCCGACGCTcaaagagaaaacgaaaatgttGAGTGTCCAATTTgcaaatgtatttatttacgCTCATCGTTGGCTGTTCACATGCGAGTTCACAACGGTGAGAGACCCTACGAGTGTCAAGTTTGTTCAAAGGCCTTCAGCACAAAATGGAATCTACAGCTGCACAAATGGACTCATGCAGCGCGCAGTACGAAACCTTTTAAATGCAATCAATGTAGCGCTGCATTTTATCGTCACAGTGACTACACAGCTCATATGAATTCTCATCGGAACGTTCGACCTTACACGTGTAACTACTGTGGGGCACAATTCATTCGTAAATACAACTGTCTGCGGCACGTCAAAGAACACGAAGAGAATAAGTCCTACACATGCGATATTTGCAACAAAACATTTCATCGATCGTATTACCTTAAAGAACATTTGCGAGTACATTCGGGTGCCAGACCCTACACTTGTCATATCTGTGGCAAGTCTAGTAGTACGAAGTCGAATCATAATAAACACGTAAGAATTCATCATGCGAGAGAACCTGTAAATACGGAAAACTAA
Protein Sequence: MELGTSMTAGAVACPVCTLYLREGISLQKHLDTHPKEQVIEALIKASSSPAQPQLNLSQPAQNPLQTPPNPVASQSPYPVGPVFECPPVASMMSPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPAVQMIAPISNVPTAQRSRPMVSVGSETNTRNNIASSLSGVDIEPKQILPEIEAEVEPEQLLPEVEIESVTGTNQHESNHADRNQSEHQTQQIQQESINQENGGGRMEYQNIVQNLTVNEDGVVVHDDKTENESVLPDIEQPESISQTQHVVPIQHEHTQTQQGEEFGHGFGASIGKERDIQSRTVDFEEEVEEDNKVDGENENLQNTVSHADINMVVERPKNSNDQPEVEQLERLLITIMETEFNVNRPKSKDKKGQEDVRDEERCDMETSAADRETSVIQETSTTSLDFQRNSLKVFETGEIRESFNSNKDIDEEEGKSEELEAGECYEQETDAQFVYNYKNSLSAPASPATQRILNRQRTYSVRSEMGSNENLSSYPVGFEATTLLDEDEEDVNEKRETVDNFDEEDMEIEEITSPHTPFTKHNENSECVRSHTPLSTISGISGLRVRTDLSKPCSPASAHSFHHMDTNSLCAEDDGEELVDPDTEKDPIDCSQLQREAELIENLKNISHKLQPNHVYHQSVITENLASFSISHHSQKPMTIHDTYESTNCQHNGDNLLDLSEPSEPTTSTDSKNFQSVKSILQKPTTELLNINEDAHPGPMNVLEFDGLQILVPSTFISESSQKAVSATSRQSMASSEGGAEADEEIKSVNMRADEIMPPRGELSEQESNGCHEPSAWQQLYMGQESSRMSTSYDLMARESWEESEGSDNEIGGPLLDSRSLATHFTSSLFLDRDRKTPTKRSFKCPHCSEIFDCPKERRVHTGTVHKEAGPSSSRDPMEQPEVKDIKLLEGRMNVFDDLFVPGLHVQQPLLHQLQPAHHPPDLTKLEVDRKIENLIVPTSIEISCPICGQLFSSDKSLQIHHRRVHISESNKRVRESAKCQTCNEEFPSVVLYNTHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKSYTCDICNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00939825;
90% Identity: iTF_01413635;
80% Identity: -