Esub010343.1
Basic Information
- Insect
- Eupithecia subumbrata
- Gene Symbol
- -
- Assembly
- GCA_949316285.1
- Location
- OX438637.1:8768756-8773291[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 0.007 0.6 11.6 0.1 1 20 112 131 112 133 0.95 2 23 0.037 3.1 9.3 2.8 1 23 163 185 163 185 0.98 3 23 0.0019 0.17 13.4 0.8 2 23 190 212 189 212 0.95 4 23 0.53 46 5.7 3.5 5 21 219 235 216 236 0.88 5 23 0.15 12 7.5 0.3 2 21 343 362 342 363 0.94 6 23 0.0015 0.13 13.7 2.0 1 23 393 416 393 416 0.96 7 23 0.00013 0.011 17.0 1.2 3 23 423 443 421 443 0.98 8 23 0.45 38 5.9 3.6 1 20 446 465 446 467 0.91 9 23 0.00054 0.046 15.1 1.1 1 23 479 502 479 502 0.94 10 23 3.5e-05 0.003 18.9 2.0 1 23 508 530 508 530 0.98 11 23 0.077 6.5 8.3 1.2 5 23 540 558 538 558 0.97 12 23 0.0017 0.15 13.5 0.9 1 23 564 587 564 587 0.98 13 23 0.015 1.3 10.5 0.3 3 23 597 618 596 618 0.96 14 23 0.00019 0.016 16.6 0.3 2 21 728 747 727 748 0.94 15 23 4.2 3.6e+02 2.8 0.0 3 23 755 776 753 776 0.93 16 23 0.1 8.8 7.9 0.0 3 23 783 804 782 804 0.92 17 23 4.4e-05 0.0037 18.5 0.6 2 23 810 831 809 831 0.95 18 23 0.028 2.4 9.7 3.5 2 20 835 853 834 855 0.93 19 23 1.6e-05 0.0013 19.9 0.3 1 23 879 902 879 902 0.95 20 23 0.00071 0.06 14.7 2.2 1 23 908 930 908 930 0.96 21 23 0.043 3.7 9.1 0.2 1 23 936 958 936 958 0.98 22 23 0.027 2.3 9.7 0.2 1 23 964 987 964 987 0.94 23 23 7.2e-05 0.0061 17.9 0.9 1 23 993 1016 993 1016 0.96
Sequence Information
- Coding Sequence
- ATGGAAGATGGCAACACTCCGCAACAGCTGTGCCAACAATGCATGTCCGACATCACCGCCTTTCTACCCTTCCTGAAACTCTGCAAGCAATCCGCTGAACATTGGAGCTTCCTATCTGAGAATTTGATCAACCCTTCTGCCCAGAAGACTTTTAACACAGCGTTCATCTTTGTCAACgataaaattgataaagttaCCACTGTGTTCGAAAAAAGGGATAGAAGCAAAAATAAGTTGTGGCATGTCGTGGCAAAGCGAATTAACCAGCTAGAGTCGGCGAGACGGACACGAGAGTCCAGCGACAATGAACCGACGAAGCCAGGAAAGTTTCTTTACACTTGCGTAGAGTGCGGCGCGAAGTTTAGTCGGTTGGACAAGATTAATAACCACTTAGCGAACCAGAAAAAGCGTTTCTGTGCTCATTGTCACGAGATTATCGATCTAAAAGCTTTTGGAAAGCATCTGGAGTCGCATTCAATCCCTTTTTATACCTGCAAGATCTGTTCCTTACCCTTTGAGTGTAAATACCAGTTGATAAAACACAAAAGTGTGCATAAAGGTAGAATCATGTGCGGGGAATGCAAAAAAACCTTTCCCTTAGCGCACTATCTAAACATTCACGTCAATAGGAAGCATGAGCGTGCTTCCTGCATCAAATGTAATAAAAAGTTTTCGAATCGTATATGTTTTAACAAGCATCGAATCAAATGCAAGTCTAGAAAGCCAGAGAAATATGTGGACGACGGCCCCGCGCTCCCGCCGGGGCTCTGCGGCGTCTGCGCAGGCGATGTTGTATCCGCCGCCAAATTCAGACAACTTACCGATAAGTCCGCGAAATGTTGGACCGAAGCGGCTCAATACCTCTCACGAATAGATAGCGAGAGCAAAGACACAAAAACTCTGCTTTACGTCTACGAAGAACACACTTTAATATTCTACGAGAAACGGGCCAAGAGTGTTAAATCTGCGGTCACAGCCCTCAGTGATTTCGGAAAGGAAACATCGATCAATAAAAAGAATCCTACTTCATGCCCATTCTGCGATAAACGGATGATTTCTGTGCAGAATCTTAACCAACATCTTAAAAACAGCTCGAAAAGAATGTGCATATGCGGCTGGCTTATGGACAAATCAGAAATCTGTAAACACTTGCGAGAGACACATAAGATTGATGTCTTCGAATGCAGTATCTGTCATGAGCAGTTTCGGAGTAATGAGGTTCTAAAGTGGCATAGCAAAAGATCCCATGGTCCTAAATCTTTCGGTTGCGAGCATTGCGGACGTGGTTACAGAAACCAGAGAGCCTTGCGGGCACATTACTACACCCACACTTTGTTCGACTGCTCCGCTTGCGGGAAAACTTTCGAGAACATCCGCTGTTACCGTCACCACAAAACTACATGTAAACCTAAACACAAAAACGACTTTACTATCTTTGAGTGTCATGACTGCGGACAGCAATATGACAAGAAAGGATCTCTTAGAATACATGTGatacaaaaacatttaaatgtCCTACCCTACGTTTGTCAGATCTGTGGCAAGCAAACTTCTACCTTAAGTCATTTAAAATCGCACTCCAAAATTCACGAGGCTGATAGGAAGACTCTAGAATGCCACTGCGGGGCTAAGTTCCGGACTGAGTTAGGGTACCGTCTACACATGAGAATACACAGCGGTTTGAGACCTTTTAAATGTGAGGAGTGCGAGGAGAGTTTTATATCAGCGTCTAGACGCTCCGATCATATGAAGAGACGACATAAGAGTGTGAAAGATATGGCGCATGGTTGCGATCAGTGCTTGGCTCGGTTCATCAGGCCTTGGGAACTGAAGAAGCATTACAAGCTCTCGCATAGTTCGATAATAAAAGAAGAGACCTTCTGTCCGGGCGGTGTTTGCGTAGCGTGCGCAAGCGCAGCGCTGGCAGCGGAAGAGTTCCGTCTATTCGTCCGCAACGCCGCCTCTCTCTGGCGCCGCGCCATCATCAACCTCTCCCAACTACCCCACGAGGCTGCCGACAACGCCAAATCCGTTTGCGCGGTCGTTTCCTCCAACGTAACTGTCGACACACACAGTGATTTCGACGCCGGCGATGCGACTGAAGTCATCGATAAATTGCAGTCGAAGTTGACTAAGAAATACGAGAGAAAACCCCGCGTTCTCCGCAGCGGGCCGACTGTAACCTGTCCTGATTGCAATAAGCAGTTCTCAGGTCCCCATTTATTGCAAACGCATCTACAGAATAGCGACAGGAAAGACGCTTGTGGAATTTGCGGCGCCGTTGTTTCTATAGGTGCAGGGTTGAAATATCATCTGACGACGGTGCACAGAGAACGCGCTATCCTGTGCAAAGAATGCCCGACCGTTGTGATAACAGAAGCTGAGCTCAAAGCACATGAGAGCTTAGCTCATAAACCTGGAGCACTGAACTGCACCGCTTGCGGAAGGACCTTTACCCGCAAAGGGTCCTACGAAAGCCATATCCAAATGCACGTCGTCTTGACCTGCAGACTCTGCGGTACCCAATTCTCTAACAGAAGCTGCTTCCGCCAACACAGATCTTTTTGCGAACCCAACGCAAAACCTAAATCAACCCACCGCATTCGTCGTTCCAACAACCGCGATCCCGGTCAATACGTGTGCGATTACTGTCAAAAGATGTACAGCTCTCGGCCGCAATTGAAGAACCATATACTCTGGATCCATTTGGACCACAGGCCGCACCAATGCTCCTTTTGCGGGAAGCGATTCTACACGTCAGCTAGGTTGAACGAGCATACCGTTGTCCACACAAGAGTTAGGAACTTCGAGTGTGATCTATGTGACGCGAAACTAGTGTCAAAAAGTGCTGCAATTTATCACAGACGACGGCATACCGGTGAGAAGCCTTACGTGTGCGACGACTGTGGAGCAGGCTTTATCTCCTCATCGAGGAGGCTAGAACACGCTAAACGGAAACATAATAAAGGGACCCGGTTCAAGTGTACGGAGTGCACCGCTAGCTTCGTGAGGAGACGGGAGCTTGAGAAACATGTGGAGAAAAATCACAAACGCTCTGTTAAGTCTGATGTATTCGAATGTGACTTCGAGGTCGCAAAGCTTGAAGTTATTTCTTAG
- Protein Sequence
- MEDGNTPQQLCQQCMSDITAFLPFLKLCKQSAEHWSFLSENLINPSAQKTFNTAFIFVNDKIDKVTTVFEKRDRSKNKLWHVVAKRINQLESARRTRESSDNEPTKPGKFLYTCVECGAKFSRLDKINNHLANQKKRFCAHCHEIIDLKAFGKHLESHSIPFYTCKICSLPFECKYQLIKHKSVHKGRIMCGECKKTFPLAHYLNIHVNRKHERASCIKCNKKFSNRICFNKHRIKCKSRKPEKYVDDGPALPPGLCGVCAGDVVSAAKFRQLTDKSAKCWTEAAQYLSRIDSESKDTKTLLYVYEEHTLIFYEKRAKSVKSAVTALSDFGKETSINKKNPTSCPFCDKRMISVQNLNQHLKNSSKRMCICGWLMDKSEICKHLRETHKIDVFECSICHEQFRSNEVLKWHSKRSHGPKSFGCEHCGRGYRNQRALRAHYYTHTLFDCSACGKTFENIRCYRHHKTTCKPKHKNDFTIFECHDCGQQYDKKGSLRIHVIQKHLNVLPYVCQICGKQTSTLSHLKSHSKIHEADRKTLECHCGAKFRTELGYRLHMRIHSGLRPFKCEECEESFISASRRSDHMKRRHKSVKDMAHGCDQCLARFIRPWELKKHYKLSHSSIIKEETFCPGGVCVACASAALAAEEFRLFVRNAASLWRRAIINLSQLPHEAADNAKSVCAVVSSNVTVDTHSDFDAGDATEVIDKLQSKLTKKYERKPRVLRSGPTVTCPDCNKQFSGPHLLQTHLQNSDRKDACGICGAVVSIGAGLKYHLTTVHRERAILCKECPTVVITEAELKAHESLAHKPGALNCTACGRTFTRKGSYESHIQMHVVLTCRLCGTQFSNRSCFRQHRSFCEPNAKPKSTHRIRRSNNRDPGQYVCDYCQKMYSSRPQLKNHILWIHLDHRPHQCSFCGKRFYTSARLNEHTVVHTRVRNFECDLCDAKLVSKSAAIYHRRRHTGEKPYVCDDCGAGFISSSRRLEHAKRKHNKGTRFKCTECTASFVRRRELEKHVEKNHKRSVKSDVFECDFEVAKLEVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00701292; iTF_00703245; iTF_00705295; iTF_00702214; iTF_00706255;
- 90% Identity
- -
- 80% Identity
- -