Dlab009002.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dryobota labecula
Gene Symbol
-
Assembly
GCA_947523025.1
Location
OX383288.1:14795282-14807156[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.3e-20 1.6e-17 64.2 0.0 6 95 6 93 2 99 0.92

Sequence Information

Coding Sequence
ATGTGTGAATGGCTATCGCACGGGGAGTGGTGCGATGTGAAACTCCTGTGCGGCGGGCGTGCATTCAGCGCACATCGCGCCGTGCTCGCCAGTGTTAGCACTTTTCTTAGACGTCTTCTCCTTTCTTGTCCCACAGATGAGTCGCCGACTTTTATCGTTTTGCCAGATTTTGACCTCGACGCTATGTCATCTGTGCTTTATTACATTTATAATGGAGAAGTCATTGTACAAAAAGAAAAAATTGAAATGTTTCTAGACATTATAAAAGCCATGCAAATATTTGTCGACTGTCAATATTTGCGGCAAGTGTCGGATACATTGGAGTATAACAATTTCGACTCAAGTTTTCACTATGAAACTGATTTGTCAAAAAGAAATATATTTACTTTAGGATTTGAAGGCTGCAGAGATCAACGATACATAAATATAAAGAAAGGCAAGGAAATCCAGGATGTATTACAGTATTCAGTTAGCAACTCAGATTGCAAAGATACGTTGGTACGTAGTAAGAATTCAAGTGGAGAGCGTCAGTCTTCTTTAGGAAATCTGAAATCGCCGTATGGAGACCGACAAAGGAACTCTTTTCTACGTGATTTATTTATCGAGACATATCCTCGAAACGGTAATGTTAACGGTCTGACGGCAGGCGTGCTAGCAATATCAAATGAATGCTATCGTGCTCCGGCATCTGTGCTCTTGACGAATGCAAATGGCAAACATCTCAGCGCCGACGGTTCACTCTTAGAACCATATAAAAAAACGAACGAGCACATCAGTCATTCGCCTACAGTATTTCACCTTCGTAAGCAGCAGCGATGCAATCGAGATGAACCAGATTACGGTGAAACTAACAAAACATTGTACGACCAATCTTGTCTAAAAGTTTGTTCGGCCGAGAAAAGTAAGAAGACACATGTTTTTGCCACTGAAACAAATAATTTACCGATGAATATATTAATGAACCATGTCCCTATATCGGCTAATCCTTTACTTCAGATGGGGATACAGGAACAAATTCTGTCAGGATTTTATGTTCCTTCCTTGGACTTTAGTATCGCACCATCAGTGTTCGATTCGATAAAACCGATGCCAGTTCATAGAAATAGATCCGTCATTGACAATGCTAGTGATGGAAGCAGTAAAGAAGTAGAGGTGGCAACGTCTGCTAAAGTAACTATTTTAAATCATGTATTAGAGAGTCCATGGAGCCCTCGGATACCTAACAACTACAAACCGTTCCGTAGAAAAACTGAACACTTGTTGAAGCCACAATTGTCTAAGCAAATAAGAAACGAAAGTAGTATAGTAAACGATAGCAATAACAATGTTCCCAAACCTAATCTATCATCAAATTCGGATGCGGTTAGTGAAACAGAGCCTGCAGGAGACGTGATAAGAGTCACAACAGTGGCGTGTCTACCAAATACCCGGAGAGATGAGTTCAAGTGCACTATTTGCAATCAGGTGTTCACGAGTGGTGAGTCGCTCGCggtacacatgcggcggcactcggcgaccgcgcggtactcgtgcggcgagtgcggcaagacgttttctcagttgcgcaacttcaagtaccacatgtccatacaccgagggaccagggagtacgcagccacctgcaccgtgtgcggcaagtacttCAATGATAGAGGATATCTCAGCAGCCACATGAAGATCCATCGGAACCGAAAAGAGTACAAGTGCACACTCTGCCCCAAGTCTTTCAATCAACGCGTTGCTTACAACATGCATGTGAGGATCCACACAGGTGTAAAGCCCCACGTGTGCGAGGAATGCGGCAAGGCGTTCTCACGCAAGATGCTACTGAAGCAGCATCAGCGCACGCATTCGGGCGAGCGCCCGTACGCCTGCCCGCACTGCGACAAGCGGTTCGCAGACCGCTCCAACATGACGCTACACTTGAGACTGCACACAGGGGTGAAGCCGTTTTCCTGCACGCTGTGTCCAAAGTCTTTTACAAAGAAGCATCACTTGAAGTCGCACCTGAACTTTCACACTGGCTCCAAGCCGTACTCGTGTCCTCGCTGCAAGCTGGCCTTCACCCAGTCGTCGAACATGAGGACGCATCTCAAGAAGTGCCGAGCGCCTGAACCAGCGACCAGTGACAGTCCTCAGTCCGGAGATACGACAGTGCAGCTGCAGACGTAG
Protein Sequence
MCEWLSHGEWCDVKLLCGGRAFSAHRAVLASVSTFLRRLLLSCPTDESPTFIVLPDFDLDAMSSVLYYIYNGEVIVQKEKIEMFLDIIKAMQIFVDCQYLRQVSDTLEYNNFDSSFHYETDLSKRNIFTLGFEGCRDQRYINIKKGKEIQDVLQYSVSNSDCKDTLVRSKNSSGERQSSLGNLKSPYGDRQRNSFLRDLFIETYPRNGNVNGLTAGVLAISNECYRAPASVLLTNANGKHLSADGSLLEPYKKTNEHISHSPTVFHLRKQQRCNRDEPDYGETNKTLYDQSCLKVCSAEKSKKTHVFATETNNLPMNILMNHVPISANPLLQMGIQEQILSGFYVPSLDFSIAPSVFDSIKPMPVHRNRSVIDNASDGSSKEVEVATSAKVTILNHVLESPWSPRIPNNYKPFRRKTEHLLKPQLSKQIRNESSIVNDSNNNVPKPNLSSNSDAVSETEPAGDVIRVTTVACLPNTRRDEFKCTICNQVFTSGESLAVHMRRHSATARYSCGECGKTFSQLRNFKYHMSIHRGTREYAATCTVCGKYFNDRGYLSSHMKIHRNRKEYKCTLCPKSFNQRVAYNMHVRIHTGVKPHVCEECGKAFSRKMLLKQHQRTHSGERPYACPHCDKRFADRSNMTLHLRLHTGVKPFSCTLCPKSFTKKHHLKSHLNFHTGSKPYSCPRCKLAFTQSSNMRTHLKKCRAPEPATSDSPQSGDTTVQLQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00623397; iTF_00667777; iTF_00122659; iTF_00122574; iTF_00667699; iTF_00273826; iTF_00273769; iTF_00274572; iTF_00809328; iTF_00809403; iTF_00274623; iTF_00810267; iTF_00810325; iTF_01094274; iTF_01095109; iTF_00924936; iTF_00925064; iTF_01093288; iTF_01095177; iTF_01093363; iTF_01094207; iTF_00071721; iTF_00071652; iTF_00121678; iTF_00121614; iTF_00123537; iTF_00123597; iTF_00124500; iTF_00746036; iTF_00124442; iTF_00745952; iTF_01028547; iTF_01230788; iTF_01118597; iTF_01026601; iTF_01031340; iTF_01119534; iTF_01027503; iTF_00111826; iTF_00111890; iTF_01031283; iTF_01119604; iTF_01118485; iTF_01026489; iTF_01028473; iTF_01027579; iTF_01230878; iTF_01192875; iTF_01192961; iTF_00772173; iTF_00772236; iTF_00888430; iTF_00888521; iTF_01029422; iTF_01029494; iTF_01117587; iTF_01117515; iTF_01030400; iTF_01030468; iTF_00120772; iTF_01247275; iTF_00120684; iTF_01247378; iTF_00374468; iTF_00374371; iTF_00685701; iTF_00685618; iTF_01527590; iTF_01527493; iTF_01062984; iTF_01063911; iTF_01063978; iTF_01062096; iTF_01062036; iTF_01063063; iTF_00043788; iTF_00043728; iTF_00041107; iTF_00041056; iTF_00040048; iTF_00040109; iTF_01535088; iTF_00928867; iTF_01535164; iTF_00928928; iTF_00042865; iTF_00042817; iTF_00301359; iTF_00302383; iTF_00302296; iTF_00301436; iTF_01084431; iTF_01084488; iTF_00446385; iTF_00446433; iTF_01085553; iTF_01085645; iTF_01285714; iTF_01285768; iTF_01339092; iTF_01339270; iTF_01361812; iTF_01361897; iTF_01440244; iTF_01440334; iTF_01526228; iTF_01526337; iTF_01425334; iTF_01425262; iTF_00173495; iTF_00173230; iTF_00852055; iTF_00851978; iTF_00037976; iTF_00038056; iTF_00425688; iTF_00425608; iTF_00726712; iTF_00726612; iTF_00952920; iTF_00952850; iTF_00974008; iTF_00973938; iTF_00445369; iTF_00445445; iTF_00906329; iTF_00906390; iTF_00072257; iTF_00072228; iTF_01377652; iTF_01377724; iTF_00758426; iTF_00758480; iTF_00951994; iTF_00952077; iTF_01363322; iTF_01363274; iTF_00039003; iTF_00039094; iTF_00850939; iTF_00851032; iTF_00036988; iTF_00037090; iTF_01441308; iTF_01441253; iTF_01534108; iTF_01534181; iTF_00147677; iTF_00147830; iTF_01340381; iTF_01340481; iTF_01532349; iTF_01532270; iTF_00177406; iTF_00177338; iTF_00712190; iTF_00712089; iTF_00908159; iTF_00908078; iTF_00907247; iTF_00364199; iTF_00364265; iTF_00907196; iTF_00375571; iTF_00831393; iTF_00831464; iTF_00449491; iTF_00449336; iTF_00375484; iTF_01064895; iTF_01064824; iTF_01533279; iTF_01533231; iTF_00237920; iTF_00238029;
90% Identity
iTF_00758480;
80% Identity
iTF_00623397;