Dvar002697.1
Basic Information
- Insect
- Drosophila varians
- Gene Symbol
- -
- Assembly
- GCA_018150405.1
- Location
- JAECWK010000130.1:16705878-16711370[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.00084 0.079 13.2 0.3 1 23 140 162 140 162 0.97 2 15 1.4 1.4e+02 3.1 3.8 1 23 168 191 168 191 0.97 3 15 2.5e-05 0.0023 18.1 2.5 1 23 369 391 369 391 0.98 4 15 0.96 91 3.6 2.0 1 23 397 420 397 421 0.93 5 15 1.3 1.2e+02 3.2 0.2 1 23 440 463 440 463 0.92 6 15 0.0007 0.066 13.5 1.9 3 23 712 732 711 732 0.92 7 15 0.028 2.6 8.4 1.4 1 23 738 761 738 761 0.98 8 15 2.1 2e+02 2.5 1.4 2 23 798 819 797 820 0.92 9 15 0.0011 0.1 12.9 0.3 1 23 841 864 841 864 0.97 10 15 0.001 0.095 13.0 0.3 1 23 1061 1083 1061 1083 0.98 11 15 0.006 0.57 10.5 3.9 1 23 1095 1117 1095 1117 0.98 12 15 2.9e-05 0.0028 17.8 0.3 2 23 1123 1145 1122 1145 0.94 13 15 0.0027 0.25 11.7 5.1 1 23 1151 1176 1151 1176 0.95 14 15 0.0011 0.1 12.9 4.1 1 23 1181 1203 1181 1203 0.97 15 15 0.057 5.4 7.5 0.5 1 23 1209 1232 1209 1232 0.86
Sequence Information
- Coding Sequence
- ATGGCGTTGAACAAAAGGTTGAGCTCCCAAGTGGACGGAGCGGACTTCAAGTTTGCGTGTCGCTGCTGTCTGAAGATGAACACCGAGTTCCTCAAGCTGGACTCGGTGACGGTGGCGCGCAGTCTGGATCCGGCGGAGGCGAAGGACAAGATTCCGCTATTGCGTTGTCTACTGTACTGTACACGCGGCGAAAATCCGGAGGAGCTTCCCCAGTACATCTGCATCGAGTGCAGTCAGAGTCTTCAGGTCGCCTACTACTTCCTTCAGAATGCAATTCGTGCACACGACATTCTGTGTCGTAAATTGTGCCCTGGCAAAGCTAGCAGGAATGCAAGGTTTAACGGTTGCATAGGCCAGGAGCTGGAACAACATTTAGAGAGCGATAATGACAGGACGAAGCCCTTGAAAACAATGCGGCACGAGTGCCAGGTTTGTGGAGTCGTCGTTTACAATCGACTGGAGCTGAAGCAGCACATACGCTTACATGCAGAGGGACTCGCGTACCACTGCAAAATGTGCAGCTTTACCACGCTAAAACAGCGGCTGCTGCAGGAACACTATCGCTCAGCCCACAACCAGAACGCAGCTCAGGCAGAAGAGCTCTCCAAGGTAAAAACGGAACCAATAAAAAAGGAAGACGAAGTGAAGGTTTGCACACTGGAGGATATGGAGCTTCTGATACCGACAGTACTGACGCCGGAGGACTACACATCCGTTCCGATCGATGCGGACCAGCTGCGGGACATTGAACAGCAGTTGGCGGCCACCATGGGTGAACCAGCGCCGGGGGTGGACACTCTAACCTCCACATTGCCGCCCATGGAAACTCAAAACGTGAGCATCGGCACTGAGTATCTCGTCTTGCCAGATGGATCGCTACAGCAGGTCAACGGTGGCGGCGTTGTCATTGAGTATATCGACGATAGCAAGCCGCCCCATCTGCACCCCCAACCCACCCCGTCTATCAACATAAATTTGCAAAATCTTCTTGGCGAGGAAAACGAAGGGATGGATATCGATGTCAACGAACTGATTGTTGAGGATGTACTGCCGCAAATAAAAGTGACGCCAAAGCCAGCGCCTGTTGGATCTCCAGTGCACAAGCACAAATGCAAATTGTGCCCCAAAACATTCGCCACTTTGGCACGTCTAAAATCTCATCAGTTGACGCACAGCCATTTGCCCAAGTTTTTCTGCGATCAGTGCGATTACTACTCACTGCGCAGTGCCGATCTCATCCAGCACTATCAGAGCCAGCACCACCGGTCGGAGGGAAATGCGGACAAAGCGAATGTTATGAAGCAGGAGGCGCGCACATATTCCTGTGACATGTGTCTGTTTGAGACGCCTACAGTGAACGAACTTCGTGTCCATTACGCGCAAAGCCATACGGTTCAACCAACGGAAGTGGAGCTGCGACCCAGTTGGACAAACGATAATAGTAGTGCTAAAACACAAAATACAGTCTTCAAGGATACGCAGTCAACTAGATTGTCAAACTCAACCGAAAACCACGTGCCCATCAAATGTAATCCTGCAGTTGCAGACACTCAGGGCCAGTTTCAGCAGCTGCCGGTGGCAACAGCGACGAGCGAAGTCATCAATGCGGTGGTAGATGCCACGCCGCATTTTTTTGCGGCCACTTCCAATGTCATTAATGCAGTGCACGCGGATCCTCCAGTGACATCAGTTGTCGCAACCACTGGCAGCCAATTCGAAATATTCCCTGAAATCTCCCAGGCCAATTTGGCGGCCAATGAAGTCGTTCCGCCAGCGCCGGCAAACACTTCCAATCCAAATATTTCCATGTTCGGCGACATGCAGGACTTTATTGACAACACCGACGTGGCCGCCATTTGCACAATTCCAGCCGACGACATGCCAGTGGTAGATGGAGATGACATCGTAATTGATAACAACAATATCAGCCTGGACTTTGACGCAGAGAATCTGTTCGAGGACTTTGAAGAGGACGAGGAGGTGCCCCCCGACGAGGAGGATGATGATGGTGAAAATGAGGACGAGAATGAAAACAATGATTCTGCCACTGATCAAAATCTGCTGCTTACCAGCGACGATGACGATGTGGACGATTTTGATGACGAGCAATCGAAGCATCTCCAAAAGCCTTATTGCATTTACTGCAACAAAAAGTTCACCAGCCAGTACAAATTTGAGAATCACATGTTTGTCCATCGGGGTCTGGCCCCATACCGCTGCGAATTGTGCACCAATCTGTACAATATGAAGCGACTTCTGATTAGGCATTATAAAACGGTGCACAAGCGAATGCCCACAAGGGACATGGTCCAGGCCAAGGGGGACAAGGTTTCCGTGGCACGATCTAGCCTCGAAAAGATCGAAACGAATTTGAACAGGAAACCTATGCTTATGTGCGCCAAGTGTCCATTCGAGTGCGAGTTGGAAGAAGAGATGCGGAAGCATTTGAATGCCCACCACGGCATCAACGATGGGGTATCTGTGCATGCCAACGAAGTGTTTATAATACGCAAACTTCCTTACGAGTGCCCGCGTTGCATTCGCTCGTTTGCGGCCAAGAGCACCCTGGTCCGCCATCTGCAGCGAAGCCATTTGGTGGAGACGATCATCGAGGTGCCTTCGCATGCAACTGCCAGTTCCGCGGCGACAACCACTACAACGACGGCCACGGCGACCACATCCGGGCCTGCCAACAGCACTCAAGATGAGGATAACCCAAGGCTAAAGATGACAATGTCGTCGACTGCTGCTGAAAGCGGCGGTGGCGATGGCAATGGGGAATGCGAGGGAACAGGCAAAGATGATGGAGCCATAGCAGGAGCCGAAACATCAATGAAAACGGAAACACTACCCAAAGAAGAAATTGATGTCGTGTCATTGGACTTCCCCGCTGTCCAAACAGCACCAAGGGCGGCTAACCCTGGAATCATAGTCACAACATCATCCACATCTCCCATTACGACCAGAGCCTCATCTGCGTCAGGCACTTTCACCAACCTTTTCCCCACACCTACACCGTTTGACTTAGATTGTGATCTGATATCAGATGTCCCAGCCCACCCATCCATTCCCACGTCCAATCCTAGCGCGCTTTTAAATGGCAGCGACAAGTTTTTACCCACATTGTCGCCAGCGGAGAAATGCCTTTCCTCCAATTCTAGACTCCCACGCGCCCCAACATACAAGTGCAAATTGTGCAGCGAAACCTTCGACGAGCTGGGGAAGCTGGTTAAACACGAGATGGTGCACTCGAACACAGAATCGTCTCGATGGAATTATCAGCACAAGTGCGCTATTTGCAATACCAGCTACCGGAATTTGACTCTGCTCAAGTTCCACATGAAGCGCCACATGAATCGCAAGGTTCAATGTAAGCTGTGCCCAAAGGCCTTCGCCAGCAACCAGGAGCTGGAGCGACACACCAAAGCCAAGCATATGCGGCAGAAGACGTTCCGATGCACTTTGGACAACTGCAAGAAGACCTTCGCATACAAACACCACATGGTGCGGCATCAGAACGCCTCGCATTTGCGGATGCGGCACGTGTGCCACATATGCGACAAGGAGCTCATGACGAGTCTGCATCTGCGAAACCACATGTCCATACACAGAAGTGGAACCTCGTACAAGTGTCCCAATTGCGATCGAACGTACTTACGTCGGGGACGAATCCGCTCGCATGCTCTGAAAGTTCATAAGCTCAAATTAACCGACGAGGAGCTGGCCGATATCTTTCGTGAGAACGTGCAAACGTGCGAGGTGCAAACTTTGAGCCGCCAGGGACAGTTGGTGCGGCGAAAGGATATAGAAGACGATACGGAAGGGAAACCTAAATCGGAATTATCACCATAG
- Protein Sequence
- MALNKRLSSQVDGADFKFACRCCLKMNTEFLKLDSVTVARSLDPAEAKDKIPLLRCLLYCTRGENPEELPQYICIECSQSLQVAYYFLQNAIRAHDILCRKLCPGKASRNARFNGCIGQELEQHLESDNDRTKPLKTMRHECQVCGVVVYNRLELKQHIRLHAEGLAYHCKMCSFTTLKQRLLQEHYRSAHNQNAAQAEELSKVKTEPIKKEDEVKVCTLEDMELLIPTVLTPEDYTSVPIDADQLRDIEQQLAATMGEPAPGVDTLTSTLPPMETQNVSIGTEYLVLPDGSLQQVNGGGVVIEYIDDSKPPHLHPQPTPSININLQNLLGEENEGMDIDVNELIVEDVLPQIKVTPKPAPVGSPVHKHKCKLCPKTFATLARLKSHQLTHSHLPKFFCDQCDYYSLRSADLIQHYQSQHHRSEGNADKANVMKQEARTYSCDMCLFETPTVNELRVHYAQSHTVQPTEVELRPSWTNDNSSAKTQNTVFKDTQSTRLSNSTENHVPIKCNPAVADTQGQFQQLPVATATSEVINAVVDATPHFFAATSNVINAVHADPPVTSVVATTGSQFEIFPEISQANLAANEVVPPAPANTSNPNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEDEEVPPDEEDDDGENEDENENNDSATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARSSLEKIETNLNRKPMLMCAKCPFECELEEEMRKHLNAHHGINDGVSVHANEVFIIRKLPYECPRCIRSFAAKSTLVRHLQRSHLVETIIEVPSHATASSAATTTTTTATATTSGPANSTQDEDNPRLKMTMSSTAAESGGGDGNGECEGTGKDDGAIAGAETSMKTETLPKEEIDVVSLDFPAVQTAPRAANPGIIVTTSSTSPITTRASSASGTFTNLFPTPTPFDLDCDLISDVPAHPSIPTSNPSALLNGSDKFLPTLSPAEKCLSSNSRLPRAPTYKCKLCSETFDELGKLVKHEMVHSNTESSRWNYQHKCAICNTSYRNLTLLKFHMKRHMNRKVQCKLCPKAFASNQELERHTKAKHMRQKTFRCTLDNCKKTFAYKHHMVRHQNASHLRMRHVCHICDKELMTSLHLRNHMSIHRSGTSYKCPNCDRTYLRRGRIRSHALKVHKLKLTDEELADIFRENVQTCEVQTLSRQGQLVRRKDIEDDTEGKPKSELSP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00566337; iTF_00488255; iTF_00539205; iTF_00477584; iTF_00476177; iTF_00550482; iTF_00481784; iTF_00580219;
- 90% Identity
- -
- 80% Identity
- -