Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000075.1:10355514-10361148[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0032 0.24 11.8 0.3 1 23 139 161 139 161 0.97

2 14 3.3e-05 0.0025 18.0 2.5 1 23 367 389 367 389 0.98

3 14 7.5 5.5e+02 1.2 1.9 1 23 395 418 395 419 0.91

4 14 0.66 49 4.5 0.4 1 23 438 461 438 461 0.93

5 14 0.00095 0.069 13.5 1.9 3 23 721 741 720 741 0.92

6 14 0.038 2.8 8.4 1.4 1 23 747 770 747 770 0.98

7 14 1.4 1e+02 3.5 0.9 2 23 807 828 806 829 0.91

8 14 0.0011 0.083 13.2 0.4 1 23 850 873 850 873 0.97

9 14 0.0014 0.099 13.0 0.3 1 23 1066 1088 1066 1088 0.98

10 14 0.0051 0.37 11.2 5.1 1 23 1100 1122 1100 1122 0.98

11 14 0.00021 0.016 15.5 0.6 2 23 1128 1150 1127 1150 0.92

12 14 0.0026 0.19 12.1 5.2 1 23 1156 1181 1156 1181 0.95

13 14 0.0094 0.69 10.3 0.7 1 23 1186 1208 1186 1208 0.97

14 14 0.33 24 5.5 3.7 1 23 1214 1237 1214 1237 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0032	0.24	11.8	0.3	1	23	139	161	139	161	0.97
2	14	3.3e-05	0.0025	18.0	2.5	1	23	367	389	367	389	0.98
3	14	7.5	5.5e+02	1.2	1.9	1	23	395	418	395	419	0.91
4	14	0.66	49	4.5	0.4	1	23	438	461	438	461	0.93
5	14	0.00095	0.069	13.5	1.9	3	23	721	741	720	741	0.92
6	14	0.038	2.8	8.4	1.4	1	23	747	770	747	770	0.98
7	14	1.4	1e+02	3.5	0.9	2	23	807	828	806	829	0.91
8	14	0.0011	0.083	13.2	0.4	1	23	850	873	850	873	0.97
9	14	0.0014	0.099	13.0	0.3	1	23	1066	1088	1066	1088	0.98
10	14	0.0051	0.37	11.2	5.1	1	23	1100	1122	1100	1122	0.98
11	14	0.00021	0.016	15.5	0.6	2	23	1128	1150	1127	1150	0.92
12	14	0.0026	0.19	12.1	5.2	1	23	1156	1181	1156	1181	0.95
13	14	0.0094	0.69	10.3	0.7	1	23	1186	1208	1186	1208	0.97
14	14	0.33	24	5.5	3.7	1	23	1214	1237	1214	1237	0.93

Sequence Information

Coding Sequence: ATGGCGTTGAACAAAAGGTTGAGCTCCCAAGCGGACGGAGCGGACTTCAAGTTTGCGTGTCGCTGCTGTCTGAAGATGAACACCGAGTTCCTTAAGCTGGACTCTGTGACGGTGGCTCGCAGTCTGGACCCAGCGGAGGCAAAGGATAAGATTCCGCTAATGCGTTGCCTGCTGTACTGTACACGCGGTGAAAACCCGGCCGAGCTTCCCCAGTACATCTGCATCGAATGCAGTCAGAGCCTCCAGGTAGCCTACTACTTCCTCCAGAACGCAGTTCGCGCGCACGAATTCCTCTGTCGCAAATTGTGTCCGTATAAGGCGTTCAAAACTCGCGTCAACGGTTCCCTAGGCCAGGAGCTGGAACAACATTTGGAGAGCGATACTGAGAGGACGAAGCCATTGAAAACAATGCGCCACGAGTGCCAGGTGTGTGGGGTCATCGTTTACAATCGCCTCGAGCTCAAGCAGCACATCCGCCTCCATGCAGATGGACTCGCTTATCACTGCAAAATGTGCAGCTTTACAACGCTAAAGCAGCGTCTGTTGCACGATCACTATCGTTCAACCCACAACCAAAACGCTACCCAGGCCGAGGAGCTTTCCAAAGTGAAGCTTGAGCCAATAAAAAAGGAAGATGAGGTAAAGGTGTGCACAATGGAGGATATGGAGCTTCTGATACCCACGGTACTAACGCCGGAGGACTACTCAGCGGTGCCAATCGATGCGGACCAGTTGCGGGATATTGAACAGCAGCTGGCGGTCACAATGGGCGAGGCAGCGCCGGGAGTGGACACTCTAACCTCCACATTACCGCCCATGGATGCCCACAACGTGAGCATCGGCACCGAGTATCTTGTCTTGCCAGATGGATCGCTGCAGCAGGTCAACGGAGGCGGCGTGGTCATTGAGTATATAGACGATAGCAAGCCCCCAAATGTTAATCCCCATCCCCCTTCCATCAACATAAACCTGCAGAATCTTCTTGGGGGTGGCGACGATGGTATGGATATTGATGTCAATGAGCTGATTGTGGAAGATGTGCTTCCGCAAATAAAAGTAACGCCAAAGCCAGCGCCGCTTGGATCTCCAGTGCACAAACACAAATGCAAATTGTGCCCCAAAACATTCGCCACTTTGGCACGTCTAAAGTCTCATCAGTTGACGCACAGCCATTTGCCGAAGTTTTTCTGCGATCAGTGCGAATACTACTCACTGCGCAGCGCCGATCTCATCCAGCACTATCAGAACCAACACCACCGGGCGGAGGGTGTTGCGGAGAAAACGGACGGTTTGAAACAGGAGGTTCGCACATACTCTTGCGACATGTGCCTCTTTGAGACGCGTACAGTCAACGAACTGCGTGTCCACTACGCACAGAGTCATACGGTTCAGCCGACGGATGTGGAGCTGCGTCCCAGCTGGACGGCCGATACTAGTAATGCCGTCAAAGATGAACCATCTGTAGACGAAAAGCCGCCGGCAAATCTACCGCCATTGACAAACTCTTCCGAAAACCACGTACCCATCAAATGTCCTCCTGCAGTTGCAGACACACAACCGGGGCAATTTCAGCAGCTGCCGGTGGAGGCAACGACATCCGTTGCCCAAACCGAGGTCATCAATGCGGTGGTAGATGCCACGCCGCATTTCTTTGCGGCCACTTCCAATTCCATTGACGCAGTTCATGCGCCACCAGTACAAGAAGTTGCCGTAACCACTGACGGGGCTCCATGCAGTTCATTCGAAATCTTTCCAGAAATCTCCCAAGGCAATTTGTCGGCTAACGAAACCGTACCGCAGGCGCCGGCAAATACTTCCAATCAAAATATTTCCATGTTCGGTGACATGCAGGATTTTATTGACAACACCGACGTGGCTGCCATATGCACCATTCCAGCCGATGATATGCCAGTGGTCGATGGCGACGACATCGTTATTGATAATAATAATATCAGCCTGGACTTTGATGCCGAAAATCTGTTCGAGGACTTTGAAGAAGACGAGGAGGTGGCGGCCGAGGAGGAGGACGATGAAGGTGATAATGAGGACGAAAACGACAACAATGATGCAGCCACGGATCAAAATCTGCTGCTAACCAGTGACGATGACGATGTCGACGATTTCGATGATGAGCAATCGAAGCATCTTCAGAAACCTTATTGTATTTATTGCAACAAAAAGTTCACCAGCCAGTACAAATTTGAGAATCACATGTTTGTTCATCGGGGTCTGGCTCCCTATCGCTGCGAGTTATGTACCAATCTCTACAACATGAAGCGACTCCTGATCAGACACTACAAAACCGTGCACAAGCGAATGCCCACAAGGGATATGGTCCAAGCCAAAGGTGACAAGGTTTCGGTGGCACGATCGAGCCTTGAAAAGATCGAAACTAACTTCAACAAGAATCCGATGCTCATGTGTGCAAAGTGTCCGTTCGAGTGTGAACCGGAGGGAGAGATGCGAAAGCATTTAAATGCCCATCACGGCATCAACGATGGGGTATCCGTTCATGCAAATGAAGTGTTTATCATACGCAAACTGCCCTTTGAGTGCCCGCGATGCATTCGCTCGTTTGCGGCCAAGAGCACCCTGATTCGCCATCTGCAGCGAAGCCATTTGGTGGAGACGATCATCGAGATGCCATCATCACAAGCAACAGCCAGTTCGGCGGCCACAACCACAACAACGACGGCCACGGCGACCACATCCGGGCCGGCCAGCAGCACTCAGGATGGAGATAGGATGACAGTATCGTCGACTGCTGCTAAAAGTGGCGGTGGCGGTGGCAATGGGGAATGCGAGGGGACAGGCAAAGATGATGGAGACCCAGCAGGAGAAGGAGCATCAATTAAAGCGGAATTAATACAACCCAAAGAGGAGATAGATGTCGTTTCATTCGGGACCTCCGCAACGGCAACCAATCCTGGAACCGCAGTAAAAACATCAACATCGCCCATTACAACCACAGCCTCATCCACATCGGCATCCTTCTCGACACTTTACCCCACGCCCACGCCATTCGACTTGGACTGTGACCTGATATCCGATGTCCCAGTCGAGCAAACCACACCCACGCCCACTACAAACTCTAATCCCAGCGCACTTTTGAATGGCAGTGATAAGTTTCTGTCAAGTCTGCCCCAAGCAGAGAAATATGTACCATCCAATTCCCGACTCCCACGCACCCCATCATACAAGTGCAAGTTGTGCAGCGAGACATTCGACGAGCTGGGAAAGCTGGTTAAGCACGAGATGGTGCACTCGAGTACGGAATCTAATCGGTATAACTATCAACACAAGTGCACTATTTGCAACACCAGCTACCGCAATCTGACTTTGTTGAAGTTTCACATGAAACGGCACACGAATCGCAAGATTCAGTGCAAGCTATGCCCAAAGTCTTTCGCAACCAACCAGGAGCTGGATCGTCACTCGAAGGCCAAGCATATGAGACCGAAGACGTTCCGGTGCACGTTGAACAACTGCAACAAGACGTTCGCATACAAGCACCACATGGTGCGGCATCAGAATGCGACCCACTTGCAGACGCGGCACGTGTGCACCATATGCGACAAGGAGATGATGACCAGCCTACTACTGCGGAACCACATGTCCGTACACAAAAGTGGAACGCTGTATAAGTGTCCACATTGTGATCGACAATATTTACGTCGGGGACGGATTTGTTCACATATTCTAAAAGTACATAAAATCAAAGCAACAGAGGCGGAACTAGCCGAAATCTTTAAGGCCAGCTCGAATGGCACGCACGAATTAAAGTCGAGGAGCCGCCAGGGACAGCTAGTGCGGCGCAAAGGATTGGATATCAAAACTGAAGTCAAAGAAGAACCGGGTCTTCAATCATCTGCAGAGGATATATAA
Protein Sequence: MALNKRLSSQADGADFKFACRCCLKMNTEFLKLDSVTVARSLDPAEAKDKIPLMRCLLYCTRGENPAELPQYICIECSQSLQVAYYFLQNAVRAHEFLCRKLCPYKAFKTRVNGSLGQELEQHLESDTERTKPLKTMRHECQVCGVIVYNRLELKQHIRLHADGLAYHCKMCSFTTLKQRLLHDHYRSTHNQNATQAEELSKVKLEPIKKEDEVKVCTMEDMELLIPTVLTPEDYSAVPIDADQLRDIEQQLAVTMGEAAPGVDTLTSTLPPMDAHNVSIGTEYLVLPDGSLQQVNGGGVVIEYIDDSKPPNVNPHPPSININLQNLLGGGDDGMDIDVNELIVEDVLPQIKVTPKPAPLGSPVHKHKCKLCPKTFATLARLKSHQLTHSHLPKFFCDQCEYYSLRSADLIQHYQNQHHRAEGVAEKTDGLKQEVRTYSCDMCLFETRTVNELRVHYAQSHTVQPTDVELRPSWTADTSNAVKDEPSVDEKPPANLPPLTNSSENHVPIKCPPAVADTQPGQFQQLPVEATTSVAQTEVINAVVDATPHFFAATSNSIDAVHAPPVQEVAVTTDGAPCSSFEIFPEISQGNLSANETVPQAPANTSNQNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEDEEVAAEEEDDEGDNEDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARSSLEKIETNFNKNPMLMCAKCPFECEPEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLIRHLQRSHLVETIIEMPSSQATASSAATTTTTTATATTSGPASSTQDGDRMTVSSTAAKSGGGGGNGECEGTGKDDGDPAGEGASIKAELIQPKEEIDVVSFGTSATATNPGTAVKTSTSPITTTASSTSASFSTLYPTPTPFDLDCDLISDVPVEQTTPTPTTNSNPSALLNGSDKFLSSLPQAEKYVPSNSRLPRTPSYKCKLCSETFDELGKLVKHEMVHSSTESNRYNYQHKCTICNTSYRNLTLLKFHMKRHTNRKIQCKLCPKSFATNQELDRHSKAKHMRPKTFRCTLNNCNKTFAYKHHMVRHQNATHLQTRHVCTICDKEMMTSLLLRNHMSVHKSGTLYKCPHCDRQYLRRGRICSHILKVHKIKATEAELAEIFKASSNGTHELKSRSRQGQLVRRKGLDIKTEVKEEPGLQSSAEDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615723;
90% Identity: iTF_00580219;
80% Identity: -