Basic Information

Insect: Drosophila anomalata
Gene Symbol: -
Assembly: GCA_035046425.1
Location: JAWNNY010001853.1:1013018-1018680[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0036 0.31 11.8 0.3 1 23 139 161 139 161 0.97

2 14 3.7e-05 0.0032 18.0 2.5 1 23 368 390 368 390 0.98

3 14 4.8 4.1e+02 1.9 1.9 1 23 396 419 396 420 0.92

4 14 0.74 63 4.5 0.4 1 23 439 462 439 462 0.93

5 14 0.0011 0.09 13.5 1.9 3 23 717 737 716 737 0.92

6 14 0.042 3.6 8.4 1.4 1 23 743 766 743 766 0.98

7 14 6 5.1e+02 1.6 1.0 2 23 803 824 802 825 0.88

8 14 0.0022 0.19 12.5 0.4 1 23 846 869 846 869 0.97

9 14 0.0015 0.13 13.0 0.3 1 23 1075 1097 1075 1097 0.98

10 14 0.023 2 9.2 3.9 1 23 1109 1131 1109 1131 0.98

11 14 0.00024 0.02 15.5 0.6 2 23 1137 1159 1136 1159 0.92

12 14 0.0029 0.25 12.1 5.2 1 23 1165 1190 1165 1190 0.95

13 14 0.014 1.2 9.9 4.3 1 23 1195 1217 1195 1217 0.97

14 14 0.089 7.6 7.4 3.8 1 23 1223 1246 1223 1246 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0036	0.31	11.8	0.3	1	23	139	161	139	161	0.97
2	14	3.7e-05	0.0032	18.0	2.5	1	23	368	390	368	390	0.98
3	14	4.8	4.1e+02	1.9	1.9	1	23	396	419	396	420	0.92
4	14	0.74	63	4.5	0.4	1	23	439	462	439	462	0.93
5	14	0.0011	0.09	13.5	1.9	3	23	717	737	716	737	0.92
6	14	0.042	3.6	8.4	1.4	1	23	743	766	743	766	0.98
7	14	6	5.1e+02	1.6	1.0	2	23	803	824	802	825	0.88
8	14	0.0022	0.19	12.5	0.4	1	23	846	869	846	869	0.97
9	14	0.0015	0.13	13.0	0.3	1	23	1075	1097	1075	1097	0.98
10	14	0.023	2	9.2	3.9	1	23	1109	1131	1109	1131	0.98
11	14	0.00024	0.02	15.5	0.6	2	23	1137	1159	1136	1159	0.92
12	14	0.0029	0.25	12.1	5.2	1	23	1165	1190	1165	1190	0.95
13	14	0.014	1.2	9.9	4.3	1	23	1195	1217	1195	1217	0.97
14	14	0.089	7.6	7.4	3.8	1	23	1223	1246	1223	1246	0.94

Sequence Information

Coding Sequence: ATGGCGTTGAACAAAAGGTTGAGCTCCCAAGCGGACGGAGCGGACTTCAAGTTTGCGTGTCGCTGCTGTCTGAAGATGAATACCGAGTTCCTCAAGCTGGACTCTGTGACGGTGGCTCGCAGTCTAGATCCGGCGGAGGCAAAGGACAAGATTCCGCTACTGCGTTGTCTGCTGTACTGTACACGCGGTGAAAACCCGGCCGAGCTTCCTCAGTACATCTGCATCGAATGCAGCCAGAGCCTTCAGGTAGCCTACTACTTCCTCCAGAACGCAGTTCGGGCGCACGACATCCTGTGTCGCAAATTGTGTCCGAATAAGGTTATCAAGACTCGCGTCAACGGTTCCTTAGGCCAGGAGCTGGAACAACATTTGGAGagcGATACTGAAAGGACGAAGCCCCTGAAAACAATGCGCCACGAGTGCCAGGTGTGTGGAGTCATCGTTTACAATCGCTTGGAGCTAAAGCAGCACATCCGCCTTCATGCAGATGGACTTGCTTATCACTGCAAAATGTGCAGCTATACCACACTGAAGCAGCGTCTGTTGCACGATCACTATCGTTCGACCCACAACCAAACCCCTGCCCAGGCAGAGGAGCTCTCTAAGGTGAAGCTGGAGCCCATAAAAAAGGAGGATGAGGTGAAGGTGTGCACCATGGAGGATATGGAGCTGCTGATACCCACAGTACTGACGCCGGAGGACTATTCAGCGGTACCGATCGACGCTGACCAACTGCGGGATATTGAACAGCAGCTGGCGGCCACAATGGGCGAGGCAGCGCCGGGGGTGGACACTCTTACCTCGACATTACCGCCCATGGATACCCAAAACGTGAGCATCGGCACCGAGTATCTTGTCTTGCCAGATGGATCTCTACAGCAGGTCAACGGAGGCGGCGTGGTCATTGAGTATATAGATGATAGCAAGCCCGCAAATTCAAATCCCCATCCCCCCTCCATCAACATAAACCTGCAGAATCTTCTGGGGGGCGACGAGAACGAGGGGATGGATATCGATGTCAATGAGCTGATTGTGGAGGATGTGCTCCCGCAAATAAAAGTAACGCAGAAGCCAGCGCCGCTTGGATCTCCAGTGCACAAGCACAAATGCAAATTGTGCCCCAAAACATTCGCCACTTTGGCACGTCTAAAGTCTCACCAGTTGACGCACAGCCATTTGCCCAAGTTTTTCTGCGATCAGTGCGAATACTACTCACTGCGCAGTGCCGATCTCATCCAGCACTATCAGAGCCAGCACCACCGGCCGGAGGGAGTTGCGGAGAAACCGGATGGTATAAAGCAGGAGGTGCGCACATACTCATGCGACATGTGCCTCTTTGAGACTCGTACTGTCAACGAACTTCGCGTCCACTATGCACAAAGTCATACGGTCCAGCCGACGGATGTGGAGCTGCGTCCCAGCTGGACGGCAGATAGCAGTCAGAATGCCAAAACCGATGATCCATCTATGGAGGAGAAGCCGCCGACTCTTCCGCCATTGACAAGCTCTTCCGAAAACCACGTACCCATCAAATGTCCTCCTGCAGTTGCAGACACACAGGGGCAATTTCAGCAGCTGCCGGTGGAAGCAACGACATCCGTTGCCCAAACCGAGGTCATCAATGCGGTGGTAGATGCCACGCCGCATTTTTTTACCGCCACTTCCAATTCCATTGACGCAGTACATGCGCCACCAGTGACAGAAGTTGCCGGAACCACTGGCGGCTCATTCGAAATCTTTCCAGAAATCTCCCAGGGCGATTTGACGGCCCAGGAATCCGTTCCACAGGCGCCGGCCAATACTTCcaatcaaaatatttccatGTTCGGCGACATGCAGGATTTCATTGACAACACCGACGTGGCTGCCATATGCACCATTCCAGCCGATGACATGCCCGTGGTAGATGGCGACGACATTGTTATTGATAACAACAATATCAGCCTGGACTTTGATGCCGAAAACCTGTTCGAGGACTTTGACGAAGACGAGGAGGTGGcggccgaggaggaggacgatgaGGGCGAAAACGAGGATGAGAATGAGAACAATGATGCAGCCACTGACCAAAACCTGCTGCTAACCAGTGACGATGACGACGTGGACGATTTCGATGATGAGCAGTCGAAGCATCTTCAGAAGCCCTACTGCATTTATTGCAACAAAAAGTTCACCAGCCAGTACAAGTTTGAGAATCACATGTTTGTGCATCGGGGTCTGGCCCCCTATCGCTGTGAATTGTGTACCAATCTGTACAACATGAAGCGACTTCTGATCAGGCACTACAAAACGGTGCACAAGCGCATGCCCACAAGGGATATGGTCCAAGCCAAAGGTGATAAGGTTACGATGGCACGCACTAGCCTTGAAAAGATCGAAACGAACCTGAACAAGAATCCTATGCTCATGTGTGCAAAGTGTCCCTTCGAGTGTGAGCCGGATGGAGAGATGCGAAAGCACTTGAATGCCCACCACGGCATCAACGATGGGgTATCAGTGCATGCAAACGAAGTGTTTATTATACGCAAGCTGCCCTTTGAGTGCCCGCGATGCATTCGCTCGTTTGCGGCCAAGAGCACCTTAGTTCGGCATCTGCAGCGAAGCCATTTGGTGGAGACGATCATCGAGATGCCATCAGCCCATGCAACAGCCAGTTCGGCGGCCacaactacaacaacgacGGCCACGGCGACCACATCCGGGCCGGCCAGCAGCACTCAGGATGAGGATAAGCCAGACCTTAAGATGACAGTATCGTCGACTGCTGCTGAAAGTGGCGGAGGCGATGGCAATGGGGAATGCGAGGGAACAGGCAGAGATGATGGAGACGTAGCAGGAGAAGGAGCATCAATGAAAGCGGAATTAACACAACCCAAAGAGGAAATCGACGTCGTTTCACTGGAGACCTCCGCTCTCCCATCAGCCGGCATATCAACAGCATCGTCAGCTCATCCTGGAACCATTGTAACAACATCAACTTCAACCATCACAACTGTAGCCTCATCCACATCGTCAACATTCTCGACAATGATCCCCACGCCCACGCCATTCGATTTAGACTGTGACCTGATATCCGATGTCCCAGCCGAGCAATCCTCCTCCACGCCCAATACCCACTCCAATCCCAGCACCCTCCTAAATGGCACGGACAAGTTTCTGTCCACTTCGCCACATGAAGAGAAGTATACACCTTCCAATTCCCGACTGCCACGCACCCCATCCTACAAGTGTAAGTTGTGCAGCGAGACGTTCGACGAACTGGGAAAGCTGGTGAAGCACGAGATGGTGCACTCGAGCACGGAATCTAATCGGTATGGATATCAGCATAAGTGCGCCATTTGCAGCACCAGCTACCGAAACTTAACCTTGCTGAAGTTCCACATGAAACGGCACACGAATCGCAAGATTCAGTGCAAGCTCTGCCCAAAGTCTTTCGCGACCAACCAGGAACTGGATCGCCACTCGAAGGCCAAGCATATGAGGCAGAAGACCTTCCGCTGCACATTGAACAACTGCAACAAGACGTTCGCGTACAAGCACCACATGGTGCGGCATCAGAATGCGACGCACTTACAGACGCGGCACGTGTGCCACATATGCGACAAGGAGATGATGACTAGCCTACATCTGCGTAACCACATGTCCGTGCACAAGAGTGGAACGTTGTACAAATGTCCGCATTGTGATCGAACATATTTGCGTCGGGGACGGATTTGTTCACATATTCTGAAAGTTCACAAAATACATGTAACCGATGAGGAACTAGCCGTAATCTTCCGCGGTAACGTAAACTCCAACAACTCTCACGATTTAAAGTCGATGAGCTGCCAGGGACAGCTAGTGCGACGCAAGGATTTGGAAATCAAAACTGAAGTGAAAGATGAACCGGGTCTTCAAACATCTACAGAGGATATATCATAA
Protein Sequence: MALNKRLSSQADGADFKFACRCCLKMNTEFLKLDSVTVARSLDPAEAKDKIPLLRCLLYCTRGENPAELPQYICIECSQSLQVAYYFLQNAVRAHDILCRKLCPNKVIKTRVNGSLGQELEQHLESDTERTKPLKTMRHECQVCGVIVYNRLELKQHIRLHADGLAYHCKMCSYTTLKQRLLHDHYRSTHNQTPAQAEELSKVKLEPIKKEDEVKVCTMEDMELLIPTVLTPEDYSAVPIDADQLRDIEQQLAATMGEAAPGVDTLTSTLPPMDTQNVSIGTEYLVLPDGSLQQVNGGGVVIEYIDDSKPANSNPHPPSININLQNLLGGDENEGMDIDVNELIVEDVLPQIKVTQKPAPLGSPVHKHKCKLCPKTFATLARLKSHQLTHSHLPKFFCDQCEYYSLRSADLIQHYQSQHHRPEGVAEKPDGIKQEVRTYSCDMCLFETRTVNELRVHYAQSHTVQPTDVELRPSWTADSSQNAKTDDPSMEEKPPTLPPLTSSSENHVPIKCPPAVADTQGQFQQLPVEATTSVAQTEVINAVVDATPHFFTATSNSIDAVHAPPVTEVAGTTGGSFEIFPEISQGDLTAQESVPQAPANTSNQNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFDEDEEVAAEEEDDEGENEDENENNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVTMARTSLEKIETNLNKNPMLMCAKCPFECEPDGEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLVRHLQRSHLVETIIEMPSAHATASSAATTTTTTATATTSGPASSTQDEDKPDLKMTVSSTAAESGGGDGNGECEGTGRDDGDVAGEGASMKAELTQPKEEIDVVSLETSALPSAGISTASSAHPGTIVTTSTSTITTVASSTSSTFSTMIPTPTPFDLDCDLISDVPAEQSSSTPNTHSNPSTLLNGTDKFLSTSPHEEKYTPSNSRLPRTPSYKCKLCSETFDELGKLVKHEMVHSSTESNRYGYQHKCAICSTSYRNLTLLKFHMKRHTNRKIQCKLCPKSFATNQELDRHSKAKHMRQKTFRCTLNNCNKTFAYKHHMVRHQNATHLQTRHVCHICDKEMMTSLHLRNHMSVHKSGTLYKCPHCDRTYLRRGRICSHILKVHKIHVTDEELAVIFRGNVNSNNSHDLKSMSCQGQLVRRKDLEIKTEVKDEPGLQTSTEDIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615723;
90% Identity: iTF_00580219;
80% Identity: -