Basic Information

Insect: Drosophila testacea
Gene Symbol: RREB1
Assembly: GCA_035043265.1
Location: JAWNND010001062.1:35079-41377[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.037 2.8 8.8 0.8 1 21 248 268 248 270 0.93

2 13 0.00035 0.026 15.2 0.2 1 23 280 302 280 302 0.98

3 13 8.3e-05 0.0064 17.1 7.3 1 23 308 330 308 330 0.98

4 13 0.51 39 5.2 2.5 2 20 545 563 545 565 0.93

5 13 0.038 2.9 8.8 0.1 1 23 729 751 729 751 0.97

6 13 1.3e-05 0.00097 19.7 0.7 1 23 761 783 761 783 0.99

7 13 0.00086 0.065 13.9 2.0 1 23 789 812 789 812 0.97

8 13 0.0031 0.23 12.2 2.0 1 23 1088 1111 1088 1111 0.95

9 13 8.9e-05 0.0068 17.0 0.3 2 23 1438 1459 1437 1459 0.97

10 13 0.15 11 6.9 6.3 1 23 1465 1488 1465 1488 0.97

11 13 4.6 3.5e+02 2.2 3.6 1 23 1619 1642 1619 1642 0.79

12 13 0.0087 0.66 10.8 0.5 3 23 1706 1726 1704 1726 0.96

13 13 0.0014 0.11 13.3 4.8 1 23 1732 1754 1732 1754 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.037	2.8	8.8	0.8	1	21	248	268	248	270	0.93
2	13	0.00035	0.026	15.2	0.2	1	23	280	302	280	302	0.98
3	13	8.3e-05	0.0064	17.1	7.3	1	23	308	330	308	330	0.98
4	13	0.51	39	5.2	2.5	2	20	545	563	545	565	0.93
5	13	0.038	2.9	8.8	0.1	1	23	729	751	729	751	0.97
6	13	1.3e-05	0.00097	19.7	0.7	1	23	761	783	761	783	0.99
7	13	0.00086	0.065	13.9	2.0	1	23	789	812	789	812	0.97
8	13	0.0031	0.23	12.2	2.0	1	23	1088	1111	1088	1111	0.95
9	13	8.9e-05	0.0068	17.0	0.3	2	23	1438	1459	1437	1459	0.97
10	13	0.15	11	6.9	6.3	1	23	1465	1488	1465	1488	0.97
11	13	4.6	3.5e+02	2.2	3.6	1	23	1619	1642	1619	1642	0.79
12	13	0.0087	0.66	10.8	0.5	3	23	1706	1726	1704	1726	0.96
13	13	0.0014	0.11	13.3	4.8	1	23	1732	1754	1732	1754	0.99

Sequence Information

Coding Sequence: ATGCTggccacacaacaacagcagcaggcacacacaacagcaacagcaacagtaacaactgctgctgaaacaacaacagcaacagcaacagttgctgagATGGATCGACAGCGTCGTGATTCGACAACCTCAGAATCATCTTTAGAACATCTCGACTTGGGACGCACACCAAAGAagctcagcagcagcaacggagCGCCGCAGCCGACGTCGACGCCACATGAcacaacgtcgacgtcgacgacaACAGCGACGTCACGCAAGCGTAAActgcgacagcagcagcaacaacaacagcaacacttgcTCTCTGACGAAGATgatgagcagcaacagcagcagcagcaacaacaacagcagcaacaattgttggATCAGTCAACGCAGCGACCGCGTCACAAGCAGCGACGCAACgccgcagttgctgctgctgccagcgccagcattgttgttgattaCAGCGCCAGCGGCGATGCCAGTTCTTTGCGTAAAAAGTTTCGTCTGAATCGCAGCAACGTTGGGGAACTCTCTGAATCGGGTTTCGTTGATGGCAGCGCCAATAGCGGCTATTTGCTCAGCAGCAGTgccggcagcagcagcgctcagtcagcaacagttgcagctgcacagcagcagcagcagacgtCAGCGTCGAGTAGCAACTCGGGTGGCTCGTCGCCTCAAGGCTTGTGCCTCTCAAGTGCCGAATCGGGAATTGGCGCCGGCGATGATCacatgaaatatttgtgcCCCATCTGTGAGGTTGTCTCGGCCACGCCCCATGAGTTCACCAATCACATACGTTGTCACAATTATGCCAACGGTGACACAGAGAATTTCACCTGCCGCATCTGCTCGAAGGTGCTGTCATCTGCCTCATCACTAGACAGGCACGTGTTGGTGCACACTGGAGAACGACCCTTCAATTGCCGTTATTGCCACTTGACATTCACTACGAACGGCAACATGCATCGTCACATGCGAACACAcaagcaacatcagcaacagtcacagcagcaacaacaacagtcgcagcagcaacagtcgcaACAACactcacagcaacaacagtcgcagtcacagcagcaacgacaacgacagcaacatgCATCGGCAACTACAATTGCCGCACAGGTGACAGGAGGCAGATCCGAAAGTTACGAAAGTGATGCAAGTTGTTCGACGGATGTGTCTAGTGCACAAagtcacagcagcagcagcaatcactccaacaataacaacaataataataacaataaactgagcaacaataacaacaacaacaacaataacaatgaggAGGAGCAACCTGCAACAAAACGACgccataaaattaatattaacaataataatattatggaAAAGGATGAGGACGAAGAGCAGGACGAGGAACAGGAAGATGACCTCGGCCAGGATGAGGATGCCTCGGATGTGGAGAGTGTGGAGGATGCCACACAAATGATAACCTCCACACCCGATGTGGCAACTCTGCTTGCCTCAGGTGGCACCACGCCCAGTCAATCACCAGCGCCCCCAATGTTGCTCAGTTGTCCCGCCTGTACGGCGGATGAATTTGAATCGTTGCCAGCCTTGTGCCAGCATCTGGATGCCCAGCATGCGGATATACCCGCCAAGTGTCGCGAATGCGAGGTAATCTTTGCCACTCACCGTCAATTGCAGACGCACAGTTGTCGTGGCATCACGGGATTGCAAATGTTGCCCTTGCTCGGCACAAGTTCGAGTCCCATACACAAGCAGGAAGTTGAGGAAGAGGACGACGAAGAGGAAGAACGCGAGGGGttggatgtggatgaggaAGATGATGAGGAGCGGGAGGAGcgagagcagcaacaactacaacagccaACAACAGCTCAACAAACGGAACGTGATGACTTTTTCCAGCAGCTCTACCTCAAAGGCAAAGCAAATGTTGCCGCTCCTTTGCCCTCACCAATTAAACATGAGATTTCCGAGCGCGGAGATTGTCGTCAGGATCTGGCGGACATACAGAGTATACTCAATATGACCAGCTCCAGTTGCACCTCGAGTTTTCTGCGTAACTTTGAGCAATCGGTAAATACCCCATGCTCCAGTCAATACAGTCTCGATGGACGGGATGGCGATGAGGAGGCTCAGGATGCATTCACCAGTGAATTTCGACGAATGAAATTACGTGGAGAATTCCCGTGTAAACTTTGCGTGGCTGTTTTCCCAAATCTACGTGCACTCAAGGGACACAATAGGGTTCATCTAGCGGCTGTTGGTCCTGCTGGTCCTTTTCGCTGCAATATGTGTCCCTATGCCGTTTGTGATAAAGCGGCGCTTGTCCGTCACATGCGCACCCACAATGGCGATCGTCCCTATGAATGTGCTGTCTGCAATTATGCGTTCACCACCAAAGCAAATTGTGAACGACATTTGCGAAATCGTCATGGAAAAACAAGTCGAGAGGAGGTGAAACGTGCCATTGTCTATCATCCTGCCGAGGATGCCAGCTGTGAGGATTCGAAATCTGGACAAAGATTACAGGATTCGGATCTAGCCGAGTTAAGCTATCGTTCAATATCGCCACCGATTGCTAATGTGGAGCCTGCCTCCCAGCTAAAGCACATGTTGCTGGCAGAGCCACCTCAGACAACAGTTGCCccagcaacaccagcagcagcaacaacagctgtcaAGGCAGCTCCATTGAAGATTCAGGTCAAAAGCTTGGATCAATTGGTGGATAAACCTTTGGCTCCTGTTTTGGATGTATGCATGGATGTGTTAGATCTCAGCAAGAAGCCAACAGCAGCACAGGAATTACAAgagcaacaccagcagcaacagcagcagcagcgtgaaagagaaagggaaCATGAATTGCTGCtgtcacagcaacagcagcaggtgcaacagcagcaacaactttttggTGCAGGGGATGCTGCCACACAGTACATGCAACAGCTGTTCCGTAATCTCATGTTCCAACAATCGCCAGCATTTCCATTCTTTAGCTTTATGCCACCAACAGCTGCCGAGAAGCCAACACAAGGCACACCGCCAACACTTGTCGGTGGCGCTGGCGGCggtgttgcaactgcaacatccGGCGTTACGCCAGCAACAAGCGCTGCTTTGGGCCTCCCAATGCCTCTGCCCGGAGTGGGTGTGGGCGTGCCTGTGCCTGCTGGTGGACCAGTCAAAATGGTTATTAAAAATGGCGTTCTAatgccaaaacaaaagcaacgtcGCTATCGCACTGAACGCCCGTTTGCCTGCGAGCACTGCTCGGCAAGATTTACACTGCGCTCAAATATGGAGCGTCATGTgaagcaacaacatccacaatTCTATGCACAACGTCAACGGAGTGGACATCATGTGATGCGTGGACGTGCTGCATCCTCCaatgcagcagctgccgcggcagcagcagcagcagccgccgccgcagcagcagcaatgtcTAATCTcacccagcaacaacatggtCATCATGCACATCATGCTCACATCTCGGACCAAGTCAAATATGCGATTCTAGCACAACAATTAAAGGCACGCAAGGATACTGACTTGTTGCAACAGGCATTGGCACATGGCTCCAGCAGTGTGGCTGGAAAtcctcttcttcattttgGATACAAGCaacacaacagcaatggcaataATCCCAGCAATGGACATCCTGTTgtcaatgatgatgatgagcccAAGTTGATAATcgatgaggatgatgaggaGGATGAGCTGGATGATGAGGAAGAAGAGCTAGATGAGATGGAGGAGGAACCAGAGCAACTGGAGGaggaacaggagcaacagGAACGAGAACATGAGCAACAAGAGCCACCACGCACTTCTACACCCATTGAGGCGGCCAAAAAAGTGGCCGAAACCATTCTGGAGCAAGCCATTAAAGCGGGAAAATCCACAGAAGTGGAGTCCAAGAAGTTAGCTAACAAATCTCCGACACCGACACCAACTCCGACTGCCACCACAATGAAAACAATGATTGCCCAAGCGGAATCTGTGGCGAAATCCCTAAAAGAAGTCGCCAGCTCACCGTTCAAAGATGAATCTCAAGATCTTGTGCCAGTTTCGAAGCTCGTTGATAATGCTACCAGCAATCAAGTGTCCTTCAACAGTTACTTTCGTCCCAGCGATGTGGCCAATCACATGGAACAGTCCGATGAGGAGGGACTTGTTGCCTCCGGCAGTGCCAGTGAGAGCAATAATTCCGGCACCGAGGATGtgaccagcagcagcagcaatgaaCCCAAAAAGAAATCCGCTTACAGTCTAGCTCCCAATCGTGTGAGTTGTCCGTATTGTCAACGTATGTTCCCCTGGAGCAGCAGCTTAAGGCGTCACATTTTAACGCATACGGGACAGAAACCCTTCAAATGTTCCCATTGTCCATTGTTGTTTACCACCAAAAGCAATTGCGATCGTCATTTGTTGAGGAAGCATGGAAATGTCGAGAGTGCCATGTCCGTTTATGTGCCCACCGAGGATGTAAGTGAACCGATTCCGGTTCCCAAATCCGTCGAGGAAATCGAGCTGGAGGAGCAGCGACGTCGCAAGGCAGAGCAACTGGAAAGGGAACGGGAAAgggagcgagaaagagagcggGAGCGGGAACAGCAACGTGAGCGAGAACGTGAATTGGAGCTGGAACGGGAGCGACGTTTGTTGGTCCAGGAACGTGAAcgggagcaacaacaacagctcatACAACAACTTGCAGCTGCAGCACAAATGGTTGCTGCCGCCGCCTGCACAGCAACCACATCCTCCTCATCCTCGCCCGCCGCAGCTGGCAGTCCACCAGCCAGCGAATCACAGGGTAGCGATCTACCCTATAAATGTCATCTATGTGAATATTCATTTGGGGAACGTCTGCAATGCCTTGAGcatattaaacaacaacatgcccATGAGTTTGCGTTGCTTCTGGCAAAGGGAGCCATTGAAACGGAGGAGCAACAATTGCCACCgccaccagcaccagcagccgcagcagctgtagcagcaacagttgctggcGTTGCATCCGATGAGGAAACTGGACTTGCCTCACGTGCCGTCAAATATCCCGATTACAGCAATCGTAAAGTCATCTGTGCCTTTTGTGTGCGTCGCTTTTGGTCCACAGAGGATTTGCGTCGTCATATGAGGACACATTCCGGAGAACGTCCATTTCAATGTGAGATCTGTTTGAGGAAATTCACATTGAAGCACAGCATGTTGAGGCACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGATTTGGGTGGACAATCCGATTGTTCCGATGATGAGcagtctgccacgcctccaagCACACCCACGCCCATGATAATGCCACaagcgaacaacaacaacaacaatacttgccacaacaacaacaataatagtaaGCAAAGTTTACGTTTGCCAAAGTTACATGAACTTTTGGACAAGGCAAATGAATGGCGTGTGAGTCGTTTAGGTgaacataaagaaaatattgccGAGACAGCAACACCatcggcagcaacagctgccgccgcggcagcagcagcagcagcagcggttGCAAGTGGCGATCTAATTGGAAATTTGCTTGGCATTAGCGATCAAGGTATACTCAATAAGTTGCTTTCCTCAGCAGATGAGGCAGCCAAGTTACTAGGCGTTGACAAGTAA
Protein Sequence: MLATQQQQQAHTTATATVTTAAETTTATATVAEMDRQRRDSTTSESSLEHLDLGRTPKKLSSSNGAPQPTSTPHDTTSTSTTTATSRKRKLRQQQQQQQQHLLSDEDDEQQQQQQQQQQQQQLLDQSTQRPRHKQRRNAAVAAAASASIVVDYSASGDASSLRKKFRLNRSNVGELSESGFVDGSANSGYLLSSSAGSSSAQSATVAAAQQQQQTSASSSNSGGSSPQGLCLSSAESGIGAGDDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQSQQQQQQSQQQQSQQHSQQQQSQSQQQRQRQQHASATTIAAQVTGGRSESYESDASCSTDVSSAQSHSSSSNHSNNNNNNNNNKLSNNNNNNNNNNEEEQPATKRRHKININNNNIMEKDEDEEQDEEQEDDLGQDEDASDVESVEDATQMITSTPDVATLLASGGTTPSQSPAPPMLLSCPACTADEFESLPALCQHLDAQHADIPAKCRECEVIFATHRQLQTHSCRGITGLQMLPLLGTSSSPIHKQEVEEEDDEEEEREGLDVDEEDDEEREEREQQQLQQPTTAQQTERDDFFQQLYLKGKANVAAPLPSPIKHEISERGDCRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEDSKSGQRLQDSDLAELSYRSISPPIANVEPASQLKHMLLAEPPQTTVAPATPAAATTAVKAAPLKIQVKSLDQLVDKPLAPVLDVCMDVLDLSKKPTAAQELQEQHQQQQQQQREREREHELLLSQQQQQVQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFSFMPPTAAEKPTQGTPPTLVGGAGGGVATATSGVTPATSAALGLPMPLPGVGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAMSNLTQQQHGHHAHHAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLLHFGYKQHNSNGNNPSNGHPVVNDDDEPKLIIDEDDEEDELDDEEEELDEMEEEPEQLEEEQEQQEREHEQQEPPRTSTPIEAAKKVAETILEQAIKAGKSTEVESKKLANKSPTPTPTPTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLEREREREREREREREQQRERERELELERERRLLVQEREREQQQQLIQQLAAAAQMVAAAACTATTSSSSSPAAAGSPPASESQGSDLPYKCHLCEYSFGERLQCLEHIKQQHAHEFALLLAKGAIETEEQQLPPPPAPAAAAAVAATVAGVASDEETGLASRAVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGDLGGQSDCSDDEQSATPPSTPTPMIMPQANNNNNNTCHNNNNNSKQSLRLPKLHELLDKANEWRVSRLGEHKENIAETATPSAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558115; iTF_00575813; iTF_00586162; iTF_00602041; iTF_00583902;
90% Identity: iTF_00558115;
80% Identity: -