Dsub017552.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila suboccidentalis
Gene Symbol
RREB1
Assembly
GCA_037043435.1
Location
JBAMBK010002558.1:790767-797527[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.041 3 8.7 0.8 1 21 259 279 259 281 0.93
2 13 0.00038 0.028 15.1 0.2 1 23 291 313 291 313 0.98
3 13 9.1e-05 0.0067 17.1 7.3 1 23 319 341 319 341 0.98
4 13 2.6 1.9e+02 3.1 2.5 2 20 567 585 567 587 0.93
5 13 0.041 3 8.7 0.1 1 23 749 771 749 771 0.97
6 13 1.4e-05 0.001 19.6 0.7 1 23 781 803 781 803 0.99
7 13 0.00094 0.068 13.9 2.0 1 23 809 832 809 832 0.97
8 13 0.0034 0.24 12.2 2.0 1 23 1116 1139 1116 1139 0.95
9 13 9.8e-05 0.0071 17.0 0.3 2 23 1486 1507 1485 1507 0.97
10 13 0.16 12 6.8 6.3 1 23 1513 1536 1513 1536 0.97
11 13 5.1 3.7e+02 2.2 3.6 1 23 1665 1688 1665 1688 0.79
12 13 0.0095 0.69 10.7 0.5 3 23 1753 1773 1751 1773 0.96
13 13 0.0015 0.11 13.2 4.8 1 23 1779 1801 1779 1801 0.99

Sequence Information

Coding Sequence
ATGCTGGccacacaacagcaacaacaacacacaacagcaactgttgctgctgcaacaacaacagcagcagcaacaacaacagttgcacaCAGCAGCGATGCCAGCGTCGACATGGATCGCCAGCGTCGTGATTCAACCACCTCAGAGTCCTCGCTGGAGCATCTCGACTTGGGCCGCACACCAAAGaagctcagcagcagcagcggagcGCCGCAGCCTACGTCGACGCCGCACgacacaacaacgacgactgcgacggcgacgtcgCGCAAGCGCAAgctgcggcagcagcagcagcaccaacatTTGCTCTCCGATGACGatgagcagctgcagcagcagcaacaacaacaacagttggaTCAGTCTGCGCAGCGACCGCGGCACAAGCAGCGACGCAGCGCCAACGCTGCCGCAGCCAGCGCCAGCATTGTCGTCGATTACAGCGCCAGCGGCGACGCCAGTTCGCTGCGTAAAAAGTTTCGACTGAATCGTAGCAGCGGCGTcggcagtggcagcggcagcggcgtcAACGGCGAACTCTCTGAATCGGGTTTCGTTGATGGCAGCGCTCACAGCGGTTATTTGCTAAGCAGCAGCGCCGGCAGCAGCGCACAGTCAGCGTCGGCAGCGGCCGtggccgcagcagcagccgccgcagTGGCAGCGCAGCAGGCGTCAGCGTCGAGCAGCTCGGGCGGCTCGTCACCTCAAGGCCTGTCGTGCCTGTCGAGCGCCGAATCGGGAATCGGCGCCGGCGACGATCACATGAAATATCTGTGCCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGTTGCCACAATTACGCCAACGGCGACACTGAGAATTTCACCTGCCGCATTTGCTCAAAGGTGTTGTCGTCGGCCTCGTCGCTGGACAGACACGTGCTGGTGCACACGGGAGAGCGACCCTTTAACTGCCGTTATTGCCACTTGACATTCACAACGAACGGCAACATGCATCGTCACATGCGAACACACAAGCAACATCAAACGcagtcacagcagcaacagtcgcaatcgcagcagcaacagcagtcacagtcacagcagcagcagtcgcagtcacagcagcaacagcagcgacgacagcaacatgcaacaacaacaacaattgccacACCGTCAGCAGGTGGCAGATCCGAGAGTTATGAGAGTGATGCGAGTTGCTCAACGGATGTGTCCAGTGCACAAagtcacagcagcaacagcagcagcagcaatcactccaacaacaacaacaacaataacaacaaactgagcaacaacaacaacaataacaatgaggaggaggaggagaaggcgcagcagcaacatgttgttgctgccacaaattGTGGCAAGCAGCGACGCCATaaaatcaacatcaacaacaacaacataatggACAAAGTAgaacaggaggaggaggaggaggcggaggaggaaGTTGAGAGTGATGTGGAGAGCGCTGGGGAGGATGTGGCACAATTGATAACCTCCACGCCCGACGTGGCAACGCTGCTTGCCTCCTCCGGTGGCACGTCACCGAGCCAATCACCCGCACCGCCACCAATGATGCTGCTCCTCAATTGTCCCGCCTGCGAGGCGGATGACTTTGAATCATTGCCCGCGCTGTGGCAACATTTGGATGCCCAGCATGCGGATATACCCGCCAAGTGTCGCGAGTGCGAGGTAATCTTTGGCAGTCATCGCCAGTTGCAGACGCACAGTTGTCGTGGCTTAAATGGATTGCAGATGTTGCCACTGCTGGCGGCAAGCTCAAGTCCCAAACAGGAAATCGAGGAGTTGGATGAGGAGGAGCAGGatgaggaggaagaggagcaACAGGAAGATGAGGAGATGGAGCAGGAggagcggcagcggcagcgggaGCAAgtgcatcagcaacaacaaacggaACGTGACGAGTTCTTTCAACAGCTCTATAACAAAAGTAAATCCAATATTGTTGCTCCGTTGCCATCACCGATCAAACATGAACTGGCCACAGATCGCGGCGATTCGCGTCAGGATTTGGCGGACATTCAGAGCATCCTCAACATGACCAGCTCCAGTTGCACCTCCAGTTTTCTGCGCAACTTCGAGCAGTCGGTCAACACGCCCTGCTCCAGTCAATACTCGCTCGATGGTCGCGATGGCGATGAGGAGGCACAAGATGCATTCACCAGTGAATTCCGTCGCATGAAATTGCGCGGCGAATTCCCCTGTAAATTGTGCGTGGCCGTGTTTCCCAATCTGCGTGCACTCAAAGGCCACAATCGTGTCCATTTGGCTGCCGTGGGTCCAGCTGGTCCCTTCAGGTGCAACATGTGTCCCTACGCGGTCTGTGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGATCGTCCCTATGAGTGTGCCGTGTGCAATTATGCATTCACCACCAAGGCCAACTGTGAGCGACATTTGCGCAATCGTCACAGCAAGACGAGTCGCGAGGATGTTAAGCGTGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGTGATGACGCCAAGTCAGGCCAGAGATTGAATGATTCCGATTTGGGCGAGCTCAGTTATCGGTCCATGTCGCCAACCGTGGAGCCAGCATCGCAATTGAAGCACATGTTGCTGGCggacacaacagcagcagcagcagcaacagctgctccaGCAACACCTATAGTTGCTGCTGTCAAGGCTGCACCATCCAAGATTCAAGTCAAGAGCTTGGATCAATTGGTGGATAAACCTTTGGCGCCTGCTTTGGATCTCAGCATGGATGTTTTGGATCTTAGCAAAAAGGAGCGACCACAGGAATTGccacaggagcagcagcagcaacagcagcagcaacaacagcagcaacaacagcagcaacgagaGCAACGCGAACGCGAGCGTGAATTGCTGCTgtgtcagcaacaacagcagcagcagcaacagcagcagcagcaactttttGGCGCTGGCGATGCTGCCACACAGTACATGCAACAGCTGTTTCGCAATCTCATGTTCCAACAATCGCCAGCATTTCCATTCTTCAGCTTTATGCCACCAACAGCGGACAAAAACAGCTCAgcaaccgcagcagcagcagcagccgccacGCTGCccacaacggcagcaacagctgctgttaAGCCAGCAACAGCCGCCGCTGCTTTGGGTCTACCCTTGCCCCTGCCCGTTGTGGGCGGTGTGGGCGTGCCTGTGCCCGCAGGCGGACCCGTCAAAATGGTCATCAAAAATGGCGTCCTGatgccaaaacaaaagcaacgtcGCTATCGCACGGAGCGACCATTTGCCTGCGAGCATTGCTCGGCGAGATTCACGCTGCGCTCGAACATGGAGCGTCATGTGAAGCAGCAGCATCCGCAGTTCTATGCACAAAGGCAGCGCAGTGGACACCATGTGATGCGCGGACGCGGTGCATCCTCGaatgcagcggcagcagcagcggcagcggcagcagcagccgccgcagcagcagcagcaatgtcCAATCTGagtcagcagcaacatggTCATCATGCGCACCATGCACACATCTCGGATCAGGTGAAATATGCGATATTGGCACAGCAGTTGAAGGCACGCAAAGATACGGATCTGTTGCAACAGGCGCTGGCACATGGCTCGAGCAGCGTGGCCGGCAATCCGCTCCAGCATTTTGGCTACAAGCaatacaacagcagcaacaacagcaacagcaatggcaatggcaatggcaatccCACCAATGGACATcatgttgctgatgatgatgagcccAAATTGATTAttgatgaggatgatgagcTGGAGGAGGACTTGGATGATGATTTAATGGAggaggacgacgacgatgagCTGGATGAGGAGCAGTcggagcagcaggaggaggCTGAGGAGCAGGGACAGCAGCAGTTGGAGCAACAACCACCAAGAACTTCAACGCCCATTGAGGCGGCCAAAAAGGTGGCGGAAACCATTCTGGAGCAGGCCATCAAAGCGGGCAAAGACCAGACCAAAAAGTTGTCCACACCCACAccaactgccacgcccacgcccacagcCACTCcaacgcccacgcccacagcAACCACAATGAAAACAATGATTGCCCAAGCGGAATCCGTGGCCAAATCCCTTAAAGAAGTTGCCAGTTCACCGTTCAAAGATGAATCTCAAGATCTAGTGCCCGTTTCGAAGCTGGTGGACAATGCCACCAGCAACCAGGTGAGCTTCAATAGCTACTTTCGACCCAGCGATGTGGCCAATCACATGGAACAGTCCGATGAGGAGGGTCTCGTCGCCTCCGGCAGTGCGAGTGAGAGCAACAACTCGGGCACCGAGGACgtgaccagcagcagcagcagcagcaacgagcCCAAAAAGAAATCCGCCTACAGTTTGGCCCCCAATCGTGTCAGTTGTCCCTATTGCCAGCGCATGTTCCCCTGGAGCAGCAGCCTGAGGCGTCACATCCTGACGCATACGGGCCAGAAGCCCTTCAAGTGCTCCCACTGTCCACTGTTGTTCACCACAAAGAGCAACTGCGATCGCCATTTGTTGCGCAAGCATGGGAATGTGGAGAGCGCGATGAGTGTTTATGTGCCCACGGAGGATGTGAGCGAACCGATACCAGTGCCCAAATCTGTGGAGGAAATTGAGCTGGAGGAGCAGCGGCGACGCAAGGCGGAGCAGCTGGAGCGGGAGAGGGAGCGGGAGCTGGAGAGGGAGcgtgagagggagagggaactGGAGCGGGAGAGGGAATTGGAGagggagcgggagcgggaaTTGGAAcgggagcaacaacagctcaTCCAGCAATTGGCAGCAGCGGCACAAATGGTTGCCGCCTCCGTTTCCGCTGCCAACTCCTCCGTCTCCTCGCCACCTGGCGGAGCACCTGGCATAACCGGCGCCAACAGTCCCGGGGAAATCCAAGGCAGCGATTTGCCCTACAAGTGTCATCTCTGTGAATATTCGTTTGGCGAGCGTCTGCAATGCTTGGAGCACATCAAGCAACAGCATGCACATGAGTTTGCTTTACTCCTGGCCAAAGGTGCCATTGAAACGGaggagcaacagttgccagcagcaccagcagcagcagcagcagcagcacctgccccgccagcaacagttgcctCCGATGAGGACTCCGGACTTGCCACACGTGCCACAAACGTCAAATATCCCGATTATAGCAATCGCAAGGTGATTTGCGCCTTTTGTGTGCGTCGCTTTTGGTCCACGGAGGATTTGAGGCGTCATATGAGAACACACTCCGGTGAGCGTCCATTTCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGTTGCGGCACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGATTTGGGTGGACAATCCGATTGCTCCGATGATGAGCagtctgccacgccccccagCACGCCCACGCCCATGATAATGCCACAAacgaacaataacaataacaacaacacttgtcacaataacaacaataccaacaacaataacaacaataacagtaaaCAAAGCTTACGTTTGCCAAAATTACATGAATTGTTGGACAAGGCGAATGAATGGCGTGTGAGTCGTTCATGTGAGCATAAGGAGAACATTGCCGAATCAGCCACAGCATCGGCAGCaactgccacagcagcagctgcggcagcggcagcagttGCCGTTGCAAGTGGCGATTTAATTGGCAATTTGTTGGGCATAAGTGATCAAGGTATACTCAATAAGTTGCTTTCCTCCGCAGACGAGGCAGCTAAGCTACTAGGCGTTGACAAGTAA
Protein Sequence
MLATQQQQQHTTATVAAATTTAAATTTVAHSSDASVDMDRQRRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTTTTTATATSRKRKLRQQQQHQHLLSDDDEQLQQQQQQQQLDQSAQRPRHKQRRSANAAAASASIVVDYSASGDASSLRKKFRLNRSSGVGSGSGSGVNGELSESGFVDGSAHSGYLLSSSAGSSAQSASAAAVAAAAAAAVAAQQASASSSSGGSSPQGLSCLSSAESGIGAGDDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTQSQQQQSQSQQQQQSQSQQQQSQSQQQQQRRQQHATTTTIATPSAGGRSESYESDASCSTDVSSAQSHSSNSSSSNHSNNNNNNNNKLSNNNNNNNEEEEEKAQQQHVVAATNCGKQRRHKININNNNIMDKVEQEEEEEAEEEVESDVESAGEDVAQLITSTPDVATLLASSGGTSPSQSPAPPPMMLLLNCPACEADDFESLPALWQHLDAQHADIPAKCRECEVIFGSHRQLQTHSCRGLNGLQMLPLLAASSSPKQEIEELDEEEQDEEEEEQQEDEEMEQEERQRQREQVHQQQQTERDEFFQQLYNKSKSNIVAPLPSPIKHELATDRGDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHSKTSREDVKRAIVYHPAEDASCDDAKSGQRLNDSDLGELSYRSMSPTVEPASQLKHMLLADTTAAAAATAAPATPIVAAVKAAPSKIQVKSLDQLVDKPLAPALDLSMDVLDLSKKERPQELPQEQQQQQQQQQQQQQQQQREQRERERELLLCQQQQQQQQQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFSFMPPTADKNSSATAAAAAAATLPTTAATAAVKPATAAAALGLPLPLPVVGGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASSNAAAAAAAAAAAAAAAAAAMSNLSQQQHGHHAHHAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLQHFGYKQYNSSNNSNSNGNGNGNPTNGHHVADDDEPKLIIDEDDELEEDLDDDLMEEDDDDELDEEQSEQQEEAEEQGQQQLEQQPPRTSTPIEAAKKVAETILEQAIKAGKDQTKKLSTPTPTATPTPTATPTPTPTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLERERERELERERERERELERERELERERERELEREQQQLIQQLAAAAQMVAASVSAANSSVSSPPGGAPGITGANSPGEIQGSDLPYKCHLCEYSFGERLQCLEHIKQQHAHEFALLLAKGAIETEEQQLPAAPAAAAAAAPAPPATVASDEDSGLATRATNVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGDLGGQSDCSDDEQSATPPSTPTPMIMPQTNNNNNNNTCHNNNNTNNNNNNNSKQSLRLPKLHELLDKANEWRVSRSCEHKENIAESATASAATATAAAAAAAAVAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00608648;
90% Identity
iTF_00534044;
80% Identity
-