Dpha015346.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila phalerata
Gene Symbol
RREB1
Assembly
GCA_951394115.2
Location
OX596006.1:44848687-44855766[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.037 3.7 8.7 0.8 1 21 248 268 248 270 0.93
2 13 0.00035 0.034 15.1 0.2 1 23 280 302 280 302 0.98
3 13 8.4e-05 0.0083 17.1 7.3 1 23 308 330 308 330 0.98
4 13 0.71 70 4.7 2.4 2 20 563 581 563 583 0.93
5 13 0.038 3.7 8.7 0.1 1 23 746 768 746 768 0.97
6 13 1.3e-05 0.0013 19.6 0.7 1 23 778 800 778 800 0.99
7 13 0.00086 0.085 13.9 2.0 1 23 806 829 806 829 0.97
8 13 0.0031 0.3 12.1 2.0 1 23 1121 1144 1121 1144 0.95
9 13 8.9e-05 0.0088 17.0 0.3 2 23 1496 1517 1495 1517 0.97
10 13 0.15 15 6.8 6.3 1 23 1523 1546 1523 1546 0.97
11 13 4.6 4.6e+02 2.1 3.6 1 23 1676 1699 1676 1699 0.79
12 13 0.0087 0.86 10.7 0.5 3 23 1762 1782 1760 1782 0.96
13 13 0.0014 0.14 13.2 4.8 1 23 1788 1810 1788 1810 0.99

Sequence Information

Coding Sequence
ATGCTggccacacaacaacaacagcaacagcaacacacaacagcagcaactgttgcagctgcaacagcaacagcagcagcaacaacaacagttgccaaCGAGATGGATCGCCAGCGTCGGGATTCAACCACCTCCGAATCCTCGCTGGAGCATCTCGACCTCGGACGCACACCAAAGAagctcagcagcagcagcggagCGCCGCagccgacgtcgacgccgcACGAGACGACGACAGCGACGTCGCGCAAACGCAAActgcgacagcagcagcagcagcagcaacaacatttgctCTCCGATgacgagcagcaacaacaacagcagcaacagctggaTCAGTCTGCGCTGCGACCGCGCCACAAGCAGCGACGCAGCGCCAACGCCAACGGCAGCGCAGCCAGCGCCAGCATCATTGTCGATTACAGCGCCAGCGGCGACGCCAGTTCGCTGCGTAAAAAATTCCGACTGAAtcgcagcagcggcagcgccAGCGGCAGCGCAGTCAACGGCGAACTGTCTGAATCGGGTTTTGTCGATGGCAGCGCGCATAGCGGTTATTTGCTCAGCAGCAGCGCCGGCAGCAGCGCACAGTTAgcgtcggcagcggcagcggcagcagcctCCGCAGTTGCAGCGCAGCAGGCGTCATCGAGCAGCTCGGGCGGCTCATCGCCCCAAGGCGGCTTGTGCCTGTCGAGCGCCGAATCGGGAATCGGCGCCGGCGACGAGCACATGAAATATCTGTGCCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGTTGCCACAATTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCAAAGGTATTGTCATCGGCCTCATCGCTGGACAGACACGTGTTGGTGCACACTGGCGAGCGACCCTTCAACTGCCGTTATTGCCACTTGACATTCACAACGAACGGCAACATGCATCGTCACATGCGCACACACAAGCAACATCAGGcgacacagcagcaacaacagtcgcagtcgcaacAGCAATCGCACTCGCAGCAACCAcatgcacagcagcaacagtcgcaTTCGCACCGACGACAGCAAcatgtggcaacaacagcaacaacaacgacaacgacaacaacaaatcaaatgaCAGGTGGCAGATCGGAGAGTTATGAAAGTGATGCAAGTTGCTCAACGGATGTGTCCAGTGCACAAagtcacagcagcaacagcagcagcagcaatcactccaacaacaacaacaacaataacaataacaaactaagcaacaacaacaataacaacaacaacaatgaggaGAAAGATGAGGAGGAGCATGTGGCTGCCACAATGTGTGGCAAGCAGCGACGCCATAaaatcaacatcaacaacaacaatattatgGAAAAGGATGAACCAgaggatgaggaggaggaggaggagcaagAGGAGCACGATCAAATGGCCTCGGATGTGGAGAGTGTTGAGGATGTGGCACAAATGATAACCTCCACACCCGATGTGGCAACCCTGTTGGCCTCATCCGGTGCCACAACACCAAGTCAATCGCCCGCACCAGCAATGATGTTGCTACTCAATTGTCCCGCCTGCGATGCGGATGATTTTGAATCATTGCCAGCACTGTGGCAACATTTGGATGCCCAGCATGCGGATATACCCGCCAAGTGTCGCGAATGCGAGGTAATCTTTGCCAGCCATCGACAATTGCAGACGCACAGTTGTCGTGGCATCAATGGCATGCAAATGTTGCCGCTACTTGCCGCCAGTTCAAGTCCCAAGCATGAAATCGAAGAggatgacgacgacgaggaGCAGGAGGACGACGAGGAGCGCATGTTGCAAGATGacgaggagcagcagcagcagcagcatcatcgACATGTTGATGAGCAAGTGCATCAGCAACATGAACGCGATGACTTCTTTCAGCAGCTATATCACAAGGGTAAATCAAATATTGCCGCTCCCTTACCCTCACCGATCAAACATGAACTTGCCACCGATCGTGGCGATAGTCGTCAGGATCTGGCCGATATCCAGAGTATCCTCAACATGACCAGCTCCAGTTGTACCTCCAGTTTTCTGCGCAATTTCGAGCAATCGGTGAACACTCCGTGCTCCAGTCAGTACAGTCTCGATGGACGCGATGGCGATGAGGAGGCACAGGATGCATTCACCAGTGAATTTCGACGCATGAAATTACGCGGTGAATTCCCCTGTAAATTGTGTGTCGCCGTTTTTCCCAATTTGCGTGCCCTCAAGGGTCACAATCGTGTACATTTGGCAGCTGTTGGTCCTGCCGGACCCTTTCGCTGCAACATGTGTCCGTACGCCGTATGCGATAAGGCGGCCCTGGTACGGCACATGCGCACCCATAACGGTGATCGTCCCTACGAATGTGCCGTCTGCAATTATGCCTTCACCACCAAGGCGAATTGTGAGCGTCACTTGAGGAATCGTCATAGTAAAACCAGTCGCGAGGATGTCAAACGTGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGTGAGGAATCCAAGTCCGGACAAAGATTAAACGATTCGGAGCTGGCCGAGTTGAGTTATCGTTCCATGTCGCCGCCCTTGGAGACAGCATCGCAATTGAAGCACATGTTGCTGGCGGACacggcagcaacagttgccgctacaccaacaccaacaccagcagcagcaacagcagcaacagttgctgtcaAGGTGGCTCCATTGAAAATACAAGTCAAGAGCCTGGATCAATTGGTGGATAAACCATTGGCGCCTGCCTTGGATCTCAGCATGGATGTTTTGGATCTCAGCAAAAAGGAGCGTCCGCAGGAATTgcaacaggagcaacaacagcagcagcagcagcagcaacagcaacaacaacgtgaGCGCGAGCGTGAATTGCTGCTgtgtcagcaacaacagcaggtgcaacagcagcaacagcagcagcaacttttTGGTGCTGGCGATGCTGCCACACAGTACATGCAACAGCTGTTCCGTAATCTCATGTTCCAACAATCGCCAGCATTTCCATTCTTTAGCTTTATGCCACAAGCAgctgccgccgctgctgctgctgctgctggcgagAAGAGCAacgcagcaacatcagcagctatgcccacaacaacagcagccgcagccgcagcagcaacatcagctgTTACACCAGCAACAAACGCTGCTTTGGGTCTACCATTGCCACTGTCCGCTGTGGGCGGTGTGGGCGTGCCTGTGCCCGCCGGCGGACCCGTTAAAATGGTCATTAAAAATGGCGTCCTGatgccaaaacaaaaacaacgtcGCTATCGCACCGAACGTCCATTTGCCTGTGAGCATTGCTCGGCCAGATTCACGCTGCGCTCCAACATGGAGCGTCATGTGAAGCAACAACATCCACAATTCTATGCCCAACGCCAGCGCAGTGGACACCATGTGATGCGTGGACGTGCTGCATCCtcaaatgctgctgctgctgcagcagctgctgctgccgccgccgccgcagccgcagcagcaatGTCCAATCTGagtcagcaacaacatggTCATCATGCACATCATGCACACATCTCGGAGCAGGTGAAATATGCGATTTTGGCACAACAGTTGAAGGCACGCAAGGATACGGATCTGTTGCAACAGGCATTGGCACATGGTTCCAGCAGTGTGGCCGGTAATCCGTTGCTGCATTTTGGCTACAAGCAACATAACAACCATAGCAATGGTAATGCTATACCCCATTCCCAAGGCAATGGACATCATGTTGCTgtcaatgatgatgatgagcccAAGTTGATAATCGATGAGGATGATGAggaggagggggagggggagggggaggaaGAGCTTGAGGATGAGTTGGAGGATGCTGAGGAGGAGGATGAGCTGGATGAGGAGCCGGAACAGCTGctggaggagcaggagcaggagctgcaacagccggagcaggagcaggaaccAACACGCACTTCAACGCCCATTGAGGCGGCCAAAAAGGTGGCGGAAACCATTCTGGAGCAGGCCATCAAAGCGGGCAAGTCCACAGAATTGGAAGCCAAAAAGTTGGCCACTCCAGCTCCCACGGCCACGCCCACGCCGACTGCAACGCCCACGCCCACAGCCACCACCATGAAAACAATGATTGCCCAAGCCGAATCCGTGGCGAAATCCCTTAAAGAAGTGGCCAGTTCACCATTTAAAGATGAATCTCAAGATCTGGTGCCCGTGGCCAAGCTGGTGGACAATGCCACCAGCAATCAGGTCAGTTTCAACAGCTACTTTCGTCCCAGCGATGTGGCCAATCACATGGAGCAATCCGATGAGGAGGGACTCGTTGCCTCCGGCAGTGCCAGTGAGAGCAACAATTCCGGCACCGAAGAtgtcaccagcagcagcagcaatgagCCCAAAAAGAAATCCGCCTACAGTTTGGCCCCCAATCGTGTCAGTTGTCCCTATTGCCAGCGCATGTTCCCCTGGAGCAGCAGCCTGAGGCGTCACATCCTGACGCATACGGGTCAGAAGCCCTTCAAGTGCTCCCACTGTCCACTGTTGTTCACCACCAAAAGCAATTGCGATCGTCACTTGTTGCGGAAGCACGGCAATGTGGAGAGTGCGATGAGTGTTTATGTGCCCACCGAGGATGTGAGTGAACCGATACCAGTGCCCAAATCCGTGGAAGAAATCGAACTGGAGGAGCAGCGACGTCGCAAGGCGGAGCAGCTGGAAAGGGAGCgtgaacgggaacgggaacgggaaatGGAACGAGAGCGGGAGCGTGAAAGGGAGCGGGAGCGTGAACGGGAGCGGGAACGTGAACTggagcgggagcgggagcagcaacaacaacagctcatCCAACAATTGGCTGCTGCGGCACAAATGGTGGCAGCCGCCTCCGTTGCCGCTGCCTCGCCGCCCGTATCCGTCACCGGAGCCGTCCCCGGAGCCGGTAGTCCCAGCGAATCCCAAGGCAGCGATTTACCCTATAAATGTCATCTGTGTGAATATTCGTTTGGCGAACGTCTGCAGTGTCTGGAGCACATCAAACAGCAACATCCACACGAGTTTGCCTTGCTCCTGGCCAAAGGTGCTATTGAAACGGAGGAGCAACCACCGTCAGCAACAGCTGTACCTCCTGCGGTCGCACCCAACCCGACCACTGTTGCCTCCGATGATGAAACCGGACATGCCACACGTGCCACAAATGTCAAATATCCGGATTACACCAATCGCAAGGTGATTTGTGCATTTTGTGTGCGTCGCTTTTGGTCCACGGAGGATTTACGCCGTCATATGCGTACACATTCCGGCGAACGACCGTTTCAGTGTGAGATCTGCTTACGGAAATTCACGTTGAAGCACAGCATGTTGCGGCACATGAAGAAGCACAGTGGACGCAATCATAATGGGGATTTGGGTGGACAGTCCGATTGTTCCGATGATGAGCAATCGGCCACGCCTCCCAGCACACCAACGCCCATGATAATGCCACaagcgaacaacaacaataacaataacacttgccacaacaacaacaacaacaataccaacaacaacaacaatagtaaaCAAAGTTTACGTTTGCCAAAATTGCATGAATTGTTGGACAAGGCGAATGAATGGCGTGTCAGTCGTTTGGGTGAACATAAGGAAAACATAGCTGAATCTTCCACACCAACGGCAGcaagtgcagcagcagcagcagcagcagcagcggcagcagcagcagctgtggCAAGTGGCGATTTAATAGGCAATTTACTGGGTATAAGTGATCAGGGTATACTTAATAAGTTGCTATCCTCTGCAGATGAGGCAGCTAAGCTACTAGGCGTTGACAAGTAA
Protein Sequence
MLATQQQQQQQHTTAATVAAATATAAATTTVANEMDRQRRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHETTTATSRKRKLRQQQQQQQQHLLSDDEQQQQQQQQLDQSALRPRHKQRRSANANGSAASASIIVDYSASGDASSLRKKFRLNRSSGSASGSAVNGELSESGFVDGSAHSGYLLSSSAGSSAQLASAAAAAAASAVAAQQASSSSSGGSSPQGGLCLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQATQQQQQSQSQQQSHSQQPHAQQQQSHSHRRQQHVATTATTTTTTTTNQMTGGRSESYESDASCSTDVSSAQSHSSNSSSSNHSNNNNNNNNNKLSNNNNNNNNNEEKDEEEHVAATMCGKQRRHKININNNNIMEKDEPEDEEEEEEQEEHDQMASDVESVEDVAQMITSTPDVATLLASSGATTPSQSPAPAMMLLLNCPACDADDFESLPALWQHLDAQHADIPAKCRECEVIFASHRQLQTHSCRGINGMQMLPLLAASSSPKHEIEEDDDDEEQEDDEERMLQDDEEQQQQQHHRHVDEQVHQQHERDDFFQQLYHKGKSNIAAPLPSPIKHELATDRGDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHSKTSREDVKRAIVYHPAEDASCEESKSGQRLNDSELAELSYRSMSPPLETASQLKHMLLADTAATVAATPTPTPAAATAATVAVKVAPLKIQVKSLDQLVDKPLAPALDLSMDVLDLSKKERPQELQQEQQQQQQQQQQQQQRERERELLLCQQQQQVQQQQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFSFMPQAAAAAAAAAAGEKSNAATSAAMPTTTAAAAAAATSAVTPATNAALGLPLPLSAVGGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAAMSNLSQQQHGHHAHHAHISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLLHFGYKQHNNHSNGNAIPHSQGNGHHVAVNDDDEPKLIIDEDDEEEGEGEGEEELEDELEDAEEEDELDEEPEQLLEEQEQELQQPEQEQEPTRTSTPIEAAKKVAETILEQAIKAGKSTELEAKKLATPAPTATPTPTATPTPTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLEREREREREREMERERERERERERERERERELEREREQQQQQLIQQLAAAAQMVAAASVAAASPPVSVTGAVPGAGSPSESQGSDLPYKCHLCEYSFGERLQCLEHIKQQHPHEFALLLAKGAIETEEQPPSATAVPPAVAPNPTTVASDDETGHATRATNVKYPDYTNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRNHNGDLGGQSDCSDDEQSATPPSTPTPMIMPQANNNNNNNTCHNNNNNNTNNNNNSKQSLRLPKLHELLDKANEWRVSRLGEHKENIAESSTPTAASAAAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00608648;
90% Identity
-
80% Identity
-