Basic Information

Insect: Drosophila neotestacea
Gene Symbol: RREB1
Assembly: GCA_035044365.1
Location: JAWNMD010000708.1:29410-35853[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.035 2.7 8.8 0.8 1 21 246 266 246 268 0.93

2 12 0.00033 0.025 15.2 0.2 1 23 278 300 278 300 0.98

3 12 7.9e-05 0.006 17.2 7.3 1 23 306 328 306 328 0.98

4 12 0.48 37 5.2 2.5 2 20 544 562 544 564 0.93

5 12 0.035 2.7 8.8 0.1 1 23 728 750 728 750 0.97

6 12 1.2e-05 0.00092 19.7 0.7 1 23 760 782 760 782 0.99

7 12 0.00081 0.062 14.0 2.0 1 23 788 811 788 811 0.97

8 12 0.0029 0.22 12.2 2.0 1 23 1088 1111 1088 1111 0.95

9 12 8.4e-05 0.0064 17.1 0.3 2 23 1438 1459 1437 1459 0.97

10 12 0.14 11 6.9 6.3 1 23 1465 1488 1465 1488 0.97

11 12 0.0082 0.63 10.8 0.5 3 23 1667 1687 1665 1687 0.96

12 12 0.0013 0.099 13.3 4.8 1 23 1693 1715 1693 1715 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.035	2.7	8.8	0.8	1	21	246	266	246	268	0.93
2	12	0.00033	0.025	15.2	0.2	1	23	278	300	278	300	0.98
3	12	7.9e-05	0.006	17.2	7.3	1	23	306	328	306	328	0.98
4	12	0.48	37	5.2	2.5	2	20	544	562	544	564	0.93
5	12	0.035	2.7	8.8	0.1	1	23	728	750	728	750	0.97
6	12	1.2e-05	0.00092	19.7	0.7	1	23	760	782	760	782	0.99
7	12	0.00081	0.062	14.0	2.0	1	23	788	811	788	811	0.97
8	12	0.0029	0.22	12.2	2.0	1	23	1088	1111	1088	1111	0.95
9	12	8.4e-05	0.0064	17.1	0.3	2	23	1438	1459	1437	1459	0.97
10	12	0.14	11	6.9	6.3	1	23	1465	1488	1465	1488	0.97
11	12	0.0082	0.63	10.8	0.5	3	23	1667	1687	1665	1687	0.96
12	12	0.0013	0.099	13.3	4.8	1	23	1693	1715	1693	1715	0.99

Sequence Information

Coding Sequence: ATGCTGGccacacaacagcaacaggcacacacaacagcaacagtaacaactgctgctgaaacaacaacagcaacagttgctgagaTGGATCGACAACGTCGTGATTCGACAACCTCAGAATCATCTTTAGAACATCTCGACTTGGGACGCACACCAAAGAagctcagcagcagcaacggagCGCCGCAGCCGACGTCGACGCCACATGACACGACGTCGACGACAACAGCGACGTCACGCAAGCGTAAActgcgacagcagcagcaacaacaacagcaacacttgCTCTCTGACGAAGATgatgagcagcaacagcaccagcagcaacagcagcaacaacaacagcaacaattgttggATCAGTCAACGCAGCGACCGCGTCACAAGCAGCGACGCAACgccgcagttgctgctgctgccagcgccagcattgttgttgattaCAGCGCCAGCGGCGATGCCAGTTCTTTGCGTAAAAAGTTTCGTCTGAATCGCAGCAACGTTGGGGAACTCTCTGAATCGGGTTTCGTTGATGGCAGCGCCAATAGCGGCTATTTGCTCAGCAGCAGTgccggcagcagcagcgctcAGTCAGCgtcagcaacagttgctgctgcacagcagcagcagcagcagacgtCAGCGTCGAGTAGCAACTCGGGTGGCTCGTCGCCTCAAGGCTTGTGCCTCTCAAGTGCCGAATCGGGAATTGGCGCCGGCGATGATCACATGAAATATTTGTGCCCCATCTGTGAGGTTGTCTCGGCCACGCCCCATGAGTTCACCAATCACATACGTTGTCACAATTATGCCAACGGTGACACGGAGAACTTCACCTGCCGCATCTGCTCGAAGGTGCTGTCATCTGCCTCATCACTAGACAGGCACGTGTTGGTGCACACTGGAGAACGACCCTTCAATTGCCGTTATTGCCACTTGACATTCACAACGAACGGCAACATGCATCGTCACATGCGAACACAtaagcaacatcagcaacagtcacagcagcaacaacaacagtcgcagtcgcagcagcaacagtcgcaaCAACactcacagcaacaacagtcgcagtcgcagtcacagcagcaacgacaacgacagcaacatgcatcggcaacaacaattgccgcACAGGTGACAGGAGGCAGATCCGAAAGTTACGAAAGTGATGCAAGTTGCTCAACAGATGTGTCTAGTGCACAAagtcacagcagcagcagcaatcactccaacaataacaacaataataataacaacaaactgagcaacaacaataacaacaacaatgaggaGGAGCAACCTGCAACAAAACGACgccataaaattaatattaacaataataatattatggaaaaggatgaggatgaagaGCAGGAAGAGGAACAGGAAGATGACCTCGGCCAGGATGAGGATGCCTCGGATGTGGAGAGTGTGGAGGATGCCACACAAATGATAACCTCCACACCCGATGTGGCAACTCTGCTTGCCTCAGGTGGCACCACGCCCAGTCAATCACCAGCGCCCCCAATGTTGCTCAGTTGTCCCGCCTGTACGGCGGATGAATTTGAATCGTTGCCAGCCTTGTGCCAGCATCTGGATGCTCAGCATGCGGATATACCCGCCAAGTGTCGCGAATGCGAGGTAATCTTTGCCACTCACCGTCAATTGCAGACGCACAGTTGTCGTGGCATCACGGGATTGCAAATGTTGCCCTTGCTCGGCACAAGTTCGAGTCCCATACACAAGCAGGAAGTTGAGGAAGAGGACGACGAAGAGGAAGAACGCGAAGGGttggatgtggatgaggaAGATGATGAGGAGCGGGAGGAGcgagagcagcaacaactacaacagccaacaacagcTCAACAAACGGAACGTGATGACTTTTTTCAGCAGCTCTACCTCAAAGGCAAAGCAAATGTTGCCGCTCCTTTGCCCTCACCAATTAAACATGAGATTTCCGAGCGCGGAGACTGTCGTCAGGATCTGGCGGACATACAGAGTATACTCAATATGACCAGCTCCAGTTGCACCTCGAGTTTTCTGCGTAACTTTGAGCAATCGGTAAATACCCCATGCTCCAGTCAATACAGTCTCGATGGACGTGATGGCGATGAGGAGGCTCAGGATGCATTCACCAGTGAATTTCGACGAATGAAATTACGTGGAGAATTCCCGTGTAAACTTTGCGTGGCTGTTTTCCCAAATCTACGTGCCCTCAAGGGACACAATAGGGTTCATCTAGCGGCTGTTGGTCCTGCTGGTCCTTTTCGCTGCAATATGTGTCCCTATGCCGTTTGTGATAAAGCAGCGCTTGTCCGTCACATGCGCACCCACAACGGCGATCGTCCCTATGAATGTGCCGTCTGCAATTATGCGTTCACCACCAAAGCAAATTGTGAACGACATTTGCGAAATCGTCATGGTAAAACAAGTCGAGAGGAGGTGAAACGTGCCATTGTCTATCATCCTGCCGAGGATGCCAGCTGTGAGGATTCGAAATCTGGACAAAGACTACAGGATTCGGATCTAGCCGAGTTAAGCTATCGTTCGATATCGCCACCGATTGCTAATGTGGAGCCTGCCTCGCAGCTAAAGCACATGTTGCTCGCAGAGCCGCCACAGACAACTGTTGTCccagcaacaccagcagcggcagcaacaacagctgtcaAGGCAGCTCCATTGAAGATTCAGGTTAAAAGCTTGGATCAATTGGTGGATAAACCGTTGGCGCCTGTTTTGGATGTATGCATGGATGTGTTAGATCTCAGCAAGAAGCCAACAGCAGCACAGGAATTACAAgagcaacaccagcagcaacagcagcagcagcgtgaAAGAGAAAGGGAACATGAATTGCTGCtgtcacagcaacagcagcaggtgcaacagcagcaacaactttttggTGCAGGGGATGCTGCCACACAGTACATGCAACAGCTGTTCCGTAATCTCATGTTCCAACAATCGCCAGCATTTCCATTCTTTGGCTTTATGCCACCAACAGCTGCCGAGAAGCCCACACAAGGCACACCGCCAACACTTGTCGGTGGCGCTGGCGGCGgcgttgcaactgcaacatccgGCGTTACGCCAGCAACAAGCGCTGCTTTGGGCCTCCCAATGCCTCTGCCCGGAGTGGGTGTGGGCGTGCCTGTGCCTGCTGGTGGACCAGTCAAAATGGTCATTAAAAATGGCGTTCTaatgccaaaacaaaagcaacgtcGCTATCGCACTGAACGACCCTTTGCCTGTGAACACTGCTCGGCAAGATTTACACTGCGCTCGAATATGGAGCGTCATGtgaagcaacaacatccacaatTCTATGCACAACGTCAGCGCAGTGGACATCATGTGATGCGTGGACGTGCTGCATCCTCaaatgcagcagctgccgcggcagcagcagcagcagccgccgccgcagcagcagcaatgtcAAATCTcagccagcaacaacatggtCATCATGCACATCATGCTCACATCTCGGATCAAGTCAAATATGCGATTCTAGCACAACAATTAAAGGCACGCAAGGATACGGACTTGTTGCAACAGGCATTGGCACATGGCTCCAGCAGTGTGGCTGGAAATCCTCTTCTCCATTTTGGCTACAAGCaacacaacagcaatggcaataATCCCAGCAATGGACATCCTGTTgtcaatgatgatgatgagcccAAGTTGATAATcgatgaggatgatgaggaGGATGAGCTGGATGATGAGGAAGAAGAGCTAGATGAGATGGAGGAGGAACCAGAGCAACTGGAGGACgaacaggagcaacaggaACGAGAACATGAGCAACAAGAGCCACCACGCACTTCAACACCCATTGAGGCGGCCAAAAAAGTGGCGGAAACTATTCTGGAGCAAGCCATTAAAGCGGGTAAATCCACAGAAGTGGAGTCCAAGAAGTTAGCCAACAAATCTCCGACACCGACACCAACTCCGACTGCCAccacaatgaaaacaatgaTTGCCCAAGCGGAATCTGTGGCGAAATCCCTAAAAGAAGTCGCCAGCTCACCGTTCAAAGATGAATCTCAAGATCTTGTGCCAGTTTCGAAGCTCGTTGATAATGCCACCAGCAATCAAGTGTCCTTCAACAGTTACTTTCGTCCCAGCGATGTGGCCAATCACATGGAACAGTCCGATGAGGAGGGACTTGTTGCCTCCGGCAGTGCCAGTGAGAGCAATAACTCCGGCACCGAGGATGtgaccagcagcagcagcaatgaaCCCAAAAAGAAATCCGCTTACAGTCTAGCTCCCAATCGTGTGAGTTGTCCGTATTGTCAACGTATGTTCCCCTGGAGCAGCAGCTTAAGGCGTCACATTTTAACGCATACGGGACAGAAACCCTTCAAATGCTCCCATTGTCCCTTGTTGTTTACCACCAAAAGCAATTGCGATCGTCATTTGTTGAGGAAGCATGGAAATGTGGAGAGTGCCATGTCCGTTTATGTGCCCACCGAGGATGTAAGTGAACCGATTCCGGTTCCCAAATCCGTCGAGGAAATCGAGCTGGAGGAGCAGCGACGTCGCAAGGCAGAACAACTGGAAAGGGAACGGGAAAgggagcgagaaagagagcggGAGCGGGAACAGCAACGTGAGCGTGAACGTGAATTGGAGCTGGAACGGGAGCGTCGTTTGTTGGTCCAGGAACGTGAAcgggagcaacaacaacagctcatACAGCAACTTGCAGCTGCAGCACAAatggttgctgctgccgcctgCACAGCAACCAcatcctcctcatcctccCCTGCCGCAGCTGGCAGTCCACCAGCAGCGAATCACAGGGGAGCCATTGAAACGGaggagcaacagttgccaccgccaccagcaccagcagccgcagcagcagtcgcagcaacagttgctggcGTTGCATCCGATGAGGAAACTGGACTTGCCTCACGTGCCGTCAAATATCCCGATTACAGCAATCGTAAAGTCATCTGTGCCTTTTGTGTGCGTCGCTTTTGGTCCACAGAGGATTTGCGTCGTCATATGAGGACACATTCCGGAGAACGTCCATTTCAATGTGAGATCTGTTTGAGGAAATTCACATTGAAGCACAGCATGTTGAGGCACATGAAAAAGCACAGTGGACGCAGTCACAATGGCGATTTGGGTGGACAATCCGATTGTTCTGATGATGAGcaatctgccacgcctccaagCACACCTACGCCCATGATAATGCCACaagcgaacaacaacaacaacaacaatacttgccacaacaacaacaacaacaatagtaagCAAAGTTTACGTTTGCCAAAGTTGCATGAACTTTTGGACAAGGCAAATGAATGGCGTGTGAGTCGTTTAGGCgaacataaagaaaatattgccGAGACCGCAACACCatcggcagcaacagctgccgcCGCGGTTGCAAGTGGCGATCTAATTGGAAATTTGCTTGGCATTAGCGATCAAGGTATACTCAATAAGTTGCTATCCTCAGCAGATGAGGCAGCCAAGTTACTAGGCGTTGACAAGTGA
Protein Sequence: MLATQQQQAHTTATVTTAAETTTATVAEMDRQRRDSTTSESSLEHLDLGRTPKKLSSSNGAPQPTSTPHDTTSTTTATSRKRKLRQQQQQQQQHLLSDEDDEQQQHQQQQQQQQQQQLLDQSTQRPRHKQRRNAAVAAAASASIVVDYSASGDASSLRKKFRLNRSNVGELSESGFVDGSANSGYLLSSSAGSSSAQSASATVAAAQQQQQQTSASSSNSGGSSPQGLCLSSAESGIGAGDDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQSQQQQQQSQSQQQQSQQHSQQQQSQSQSQQQRQRQQHASATTIAAQVTGGRSESYESDASCSTDVSSAQSHSSSSNHSNNNNNNNNNKLSNNNNNNNEEEQPATKRRHKININNNNIMEKDEDEEQEEEQEDDLGQDEDASDVESVEDATQMITSTPDVATLLASGGTTPSQSPAPPMLLSCPACTADEFESLPALCQHLDAQHADIPAKCRECEVIFATHRQLQTHSCRGITGLQMLPLLGTSSSPIHKQEVEEEDDEEEEREGLDVDEEDDEEREEREQQQLQQPTTAQQTERDDFFQQLYLKGKANVAAPLPSPIKHEISERGDCRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEDSKSGQRLQDSDLAELSYRSISPPIANVEPASQLKHMLLAEPPQTTVVPATPAAAATTAVKAAPLKIQVKSLDQLVDKPLAPVLDVCMDVLDLSKKPTAAQELQEQHQQQQQQQREREREHELLLSQQQQQVQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFGFMPPTAAEKPTQGTPPTLVGGAGGGVATATSGVTPATSAALGLPMPLPGVGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAMSNLSQQQHGHHAHHAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLLHFGYKQHNSNGNNPSNGHPVVNDDDEPKLIIDEDDEEDELDDEEEELDEMEEEPEQLEDEQEQQEREHEQQEPPRTSTPIEAAKKVAETILEQAIKAGKSTEVESKKLANKSPTPTPTPTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLEREREREREREREREQQRERERELELERERRLLVQEREREQQQQLIQQLAAAAQMVAAAACTATTSSSSSPAAAGSPPAANHRGAIETEEQQLPPPPAPAAAAAVAATVAGVASDEETGLASRAVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGDLGGQSDCSDDEQSATPPSTPTPMIMPQANNNNNNNTCHNNNNNNSKQSLRLPKLHELLDKANEWRVSRLGEHKENIAETATPSAATAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00608648;
90% Identity: iTF_00608648;
80% Identity: -