Drub001617.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila rubida
Gene Symbol
-
Assembly
GCA_035046165.1
Location
JAWNOF010000012.1:13255384-13259971[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0016 0.096 13.0 2.0 1 23 213 235 213 235 0.96
2 26 0.00013 0.0075 16.5 2.8 1 23 241 263 241 263 0.99
3 26 0.11 6.7 7.2 0.3 2 20 297 315 296 316 0.94
4 26 0.0052 0.31 11.4 5.0 1 23 394 417 394 417 0.97
5 26 2.7 1.6e+02 2.8 0.6 2 22 424 444 423 444 0.92
6 26 0.91 53 4.3 0.9 1 20 453 472 453 474 0.91
7 26 0.012 0.7 10.3 1.6 1 23 483 505 483 505 0.98
8 26 0.003 0.18 12.1 1.1 1 23 585 608 585 608 0.96
9 26 0.0052 0.3 11.4 0.0 2 22 618 638 618 638 0.95
10 26 0.53 31 5.1 3.7 1 23 647 670 647 670 0.96
11 26 0.00037 0.022 15.0 0.4 2 23 698 719 697 719 0.97
12 26 0.00014 0.0081 16.4 3.8 1 23 727 749 727 749 0.98
13 26 0.045 2.7 8.4 3.5 1 23 900 923 900 923 0.95
14 26 0.0075 0.44 10.9 0.9 2 22 931 951 930 951 0.95
15 26 0.016 0.93 9.9 0.7 1 23 960 983 960 983 0.93
16 26 0.00021 0.012 15.8 1.6 1 23 1008 1030 1008 1030 0.97
17 26 0.00066 0.039 14.2 1.2 1 23 1037 1059 1037 1059 0.98
18 26 0.024 1.4 9.3 0.0 2 21 1086 1105 1085 1106 0.93
19 26 0.0062 0.36 11.2 2.3 1 23 1151 1174 1151 1174 0.96
20 26 0.021 1.2 9.5 1.4 1 23 1211 1234 1211 1234 0.96
21 26 0.00095 0.056 13.7 3.5 1 23 1257 1280 1257 1280 0.97
22 26 1.3e-05 0.00079 19.5 0.1 2 23 1308 1329 1307 1329 0.95
23 26 4.6e-05 0.0027 17.9 2.9 1 23 1335 1357 1335 1357 0.99
24 26 2.2e-06 0.00013 22.0 2.0 1 23 1363 1385 1363 1385 0.97
25 26 5.7e-08 3.4e-06 27.0 2.4 1 23 1391 1413 1391 1413 0.99
26 26 0.00098 0.057 13.7 0.2 1 21 1419 1439 1419 1443 0.91

Sequence Information

Coding Sequence
ATGTTGCCGACCGATATATGCCGGACATGTGCCCTGCATAatgttaaattgtttgcactttcAACACGCACCGAGAAATATGCGAATAAAAGTTTGTGTGACATTTTGCATGAATTAACACAAAATGATCCATTAATGGAACACTCGGATGACAATCTGCCGCAATATCTATGCGACGACTGCTTGCGTAAGTTGGAAGATGCATATGCATTTGTGTTGCAAGCCAGAAAAGTACacgagcagctgttgcataAACTGCGTAAAGGATTGCAGTGTCTGGATGAGCCACCAATTGACATATCCACGAATGACATTAAAACCGAAGCTGACCTTGGCTTGGAACACATTGGCAATGCAGAAACAGTATTGGAAGTTGGCCCCGAAGCAATTGTTGCGGCTTTGAAAATTCAACCGGAGTCcgagagcgacagcaacgCTGGCGCATCAGATACAGTTGAAAAGGACTCATTGCACTTGAAGCTAACGCAGCTGAGACGAAGCAATCGCAAAGCAAAACTTGCTGCAGACACTGACAATGAAGATAATTCTGAAAATGGTAATCTTATGTCGGTCAAGCGCCGACGTGGTCGCCCTGCGCGTTTTCCTAAAAAAGAAGCTGTCAACAACGAAGGACGACATGCTTGTGAAGTGTGTGGCAAGACATTTTCATGGCACCGTGACATGCAACGACATGCAAGAGTTCACTTCGAACAGGCTGCATACGAGTGCGACACATGTGGAAAGCGATTTCTGCGCAAGGACAAATACACTTATCACATGCGTTCGCATGAGAAACGTcaagcaaagcaacaagcaacagtgCTGCAGAGGGGCAGCGAGTTGCGCTTTGCAGAACGTCTTTATAGCGAGGGGCGTCTGCAACGCGTCGAGTGCAAGCTTTGCGACTTGCAGTTCCAGCGGATTCACGAACTGCGCGAGCATCTTACCTGTCAGCATGTTAACATTGAATCCCTGTCACAGCTCAGCATCAATAGCGATGTTGTCAGGGAACAATTTGAAGACCAACCGTTGAATCTGGATCAGGTTAAACAACAAGTGTGCGCAGATATAGCATTGGCCAACGATCAACTGGATAAGTACTGTGTTATCACCAATGCGCATGGCTATGAACTCAGTCTGAATGATTCGGACGAAGAGTCAACCGAAGCAACTCCGCCATACCAATGCTTGACATGCAATGTGTCCTTCAAGCGCAAACATCGCCTGATGCAACACACGCTGCGCAAACATACTCAAACTCCTACGCAACGTTGCAATATTTGTCAAATTGGTTTTATGTGCCCGAATCTGTTGGATCAGCATCAACGCACACAGTGCAAGAATCAATTGAAACGTCATAGCTGTCCAAACTGTCCAGCAAAATTTATCTGGTTGCAGAATCTAAAGCAACACGAATGTTCAAAACCTCAGTATCGAGGACGCCATTTTCAATGTTGTCTTTGTGATGAGCAACTAAAGAACATGTCTGCGCTGCGGTCTCATCTGCTCAATCATGGCGACGGATGTAGTGGCATTAAATCGGATCGAACTGCTGCCTACTTTCGTTGCCATTATCCTGATGGAGTGGATTGCCAGGCAGAGCTCAGCGCACGTATTGCGAACGATTTCGCGGCACACGATTATGGGAAATACTTCAGTGCCTGCTCGGATAGTGGTAGGGAACTAGACTTCTTCGACTCGGAAACGGATTCAAGCGACGTTGAACATCTCACCACCTCCACGTCTGCATTGCATTCGTGTACATTGTGCGGCGTGGCCACAACACGACTAGCTCATCTGCTGATGCATCAAGAAACCGATCACAATGACGTTAAGAACACATTGCCCAACGTTTGCGATAAATGTGGTTTTGGATTCGTGGCAGAATCTTTGCTGCAACAACATATTCGGCGGAGCTGTGGCAAGCGACATGCAAAATACCATTGCCAGCAGTGCAATCTACATTTCATCTGGCAGTTCAATTATGAGCAGCACATGGCGGTGAAGCACGAGATAGATTTAGAGATAGAAGACCATGAACAGGCGCTTAACACCAGATTGAGAAGCAAAGGCCAGCAATCCgccaaattgcaatgcaaccAATGCGAAAAGGTTTTCATCTGGCCAAAGGATTTGACGCGTCACAAGCGAATTCATCAGCCGCAAGCAACGGCTCAGTTTGAATGCACTTTCTGTGAACGTAAGTTCCATCGCAAGGATGGTCTGAAGTCCCATTTGCGTGTGCACGGCGAGCAACAGCTGGATACGACGACAGGTGCAACTGTCGACAATCTAGATGCAAGCATTTTACAGCGAATGCCTGCTGTGTTGAGCCAATTGTGTCGACCAAATGGATGCAAGCAGATCCAGTGCATGATCTGCCTGTCACAACATACAAAAATCTCCGACTTAAGAGCACATTTGGTTAAGCATCAGTTTAGCGTGGAGTTTTCGGGAGAACGTGCCATGCCGGAGAGCATTGCGAGCATATGTCGTGGTCTATATCCAGAGCAGTTAGTGCCAATGAATaagcaacaattaattgaacGTATACAAAGCGACTTGGGCAACGGCATTGAGAAGGACAGATTCGTTTCGATAACTAACGAGGCGGCAATTGAGCTTAGCCTTGACAGCAGTGAAACTGAAACGGATTCGGACTCTGCTGAGCCCCAAAGAACTGTCACTTTACGGCAATATAATTGTGATCTGTGCCATTTGAAGCTGGCACGCAAACATCAACTCTACGCACatcagttgcagcagcacactTGGCAAGAAGCGACACTCATCTGCTCGCATTGCCAGGCCAAGTTCGTtaatgagcagctgctggagcatcATTATCGCACCCTCTGTCGGAATGCGCAAAAGCGTTTCCTTTGCCGTAAGTGCCCGTTACGCTTTCGCTGGCGCGACAACCTCAAGTTGCACATGGATGTGACGCATCAAGAAGTGGCCGGTGAACAGACGAGCTTGGGCCTACAATTGACTGCAGCAAGTCTGCTACCAGTTGTCAGCTACGATTGCCAGGCATGCAATCGCAgcttcaaaatgcaaaaggaTCTCACACGCCACACATTGATGCATGCCCAGGAGTCGAGCATTTATCGGTGTCGCTGGTGTGCCCGTCGCTTTTATCGCGAGACcaatctgctgcagcacatcGAACGCCATGGCATCAACGCCACACAGCTGCCTTATGCCGAAGCTTTACTCAATTCCAGCCGTCATCCGCATGGGCAGAAATGCATCGAatgcaaagtatgcaatgtcCGTTTTCCAACAATAGCATCACTACGTGACCACTTGTCTTCCACGCCCAATGGTACTCATCATGATGTGAGCTCTATGCTCAACTACTCCATCACCAATCAGCTTGGTTATGAGCTGCATTTGGACGACTCTGAAACGGATGAGGAGGCCAAACCACCAGGCATACCCACGCACTACACTTGTGGCATGTGTCAGCTACGTTGTGTGCGCAAGTATGAGCTCTATCAGCACCAGCAGGCGATGCATCGACTGGAACGCATTACTGAGGGATGTGATCAGTGTATCTATAAGAGCGTTTCCCCTGATCTAATTGCCTATCATCGGCGGGTGCAGTGCGACAATACGGAGAAACAATTTAAGTGCTCAAAATGCAGCTACAAGTTTATGTGGGAGTCGAACTTGCTACAGCACATCCAACTGCAACACCCAAGCACTGATAATCAAGAGGCGGAGCCAACATCAACAGAGTTGCCAACGACTGAAAGCCAGATCTTTCAGTGCGGTCAGTGTCCTCGAAAGTACAACCGAAAGGACCGACTAACAGCACACGTTAAGAAGTGCCATACACTGGGCGCAGTTGGCCCAATAGTAAATGCAGCCAAAGCTGCAAAGACCGCATCTGTTGCCAAGCAGCATAAAAGTTTTCTTTGCGCCTTCTGCGGCAAGGCAGTAAGCTCCTCCTCAAATCTCATCATACACATTCGACGCCATACTGGTGAGAAGCCATTCAAGTGCGACTACTGCGACATGGCATTTCCTCGTTCCTCCGATCTGCAGTGCCATCGACGTACCCACACGGGAGAACGGCCTCACGTTTGCACAGTATGCCAAAAGGGGTTCGCACGCTCCTACAAGTTACAGCAGCACATGCGCATTCATAATGGCGAGCGTCCCTACAAATGTACCTATTGTGATAAGAGCTTCACCCAGTCTAATGATCTGACGCTCCATATTCGGAGGCACACGGGCGAGCGACCCTATCAATGTGACACATGTGGGGAGCGTTTTATTCAGGGTACAGCGCTCAAGAACCATAGACTACAGAACGGGCATTTTGAAACCGGCGATACTGTGGGTAAAGATAATTAG
Protein Sequence
MLPTDICRTCALHNVKLFALSTRTEKYANKSLCDILHELTQNDPLMEHSDDNLPQYLCDDCLRKLEDAYAFVLQARKVHEQLLHKLRKGLQCLDEPPIDISTNDIKTEADLGLEHIGNAETVLEVGPEAIVAALKIQPESESDSNAGASDTVEKDSLHLKLTQLRRSNRKAKLAADTDNEDNSENGNLMSVKRRRGRPARFPKKEAVNNEGRHACEVCGKTFSWHRDMQRHARVHFEQAAYECDTCGKRFLRKDKYTYHMRSHEKRQAKQQATVLQRGSELRFAERLYSEGRLQRVECKLCDLQFQRIHELREHLTCQHVNIESLSQLSINSDVVREQFEDQPLNLDQVKQQVCADIALANDQLDKYCVITNAHGYELSLNDSDEESTEATPPYQCLTCNVSFKRKHRLMQHTLRKHTQTPTQRCNICQIGFMCPNLLDQHQRTQCKNQLKRHSCPNCPAKFIWLQNLKQHECSKPQYRGRHFQCCLCDEQLKNMSALRSHLLNHGDGCSGIKSDRTAAYFRCHYPDGVDCQAELSARIANDFAAHDYGKYFSACSDSGRELDFFDSETDSSDVEHLTTSTSALHSCTLCGVATTRLAHLLMHQETDHNDVKNTLPNVCDKCGFGFVAESLLQQHIRRSCGKRHAKYHCQQCNLHFIWQFNYEQHMAVKHEIDLEIEDHEQALNTRLRSKGQQSAKLQCNQCEKVFIWPKDLTRHKRIHQPQATAQFECTFCERKFHRKDGLKSHLRVHGEQQLDTTTGATVDNLDASILQRMPAVLSQLCRPNGCKQIQCMICLSQHTKISDLRAHLVKHQFSVEFSGERAMPESIASICRGLYPEQLVPMNKQQLIERIQSDLGNGIEKDRFVSITNEAAIELSLDSSETETDSDSAEPQRTVTLRQYNCDLCHLKLARKHQLYAHQLQQHTWQEATLICSHCQAKFVNEQLLEHHYRTLCRNAQKRFLCRKCPLRFRWRDNLKLHMDVTHQEVAGEQTSLGLQLTAASLLPVVSYDCQACNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRETNLLQHIERHGINATQLPYAEALLNSSRHPHGQKCIECKVCNVRFPTIASLRDHLSSTPNGTHHDVSSMLNYSITNQLGYELHLDDSETDEEAKPPGIPTHYTCGMCQLRCVRKYELYQHQQAMHRLERITEGCDQCIYKSVSPDLIAYHRRVQCDNTEKQFKCSKCSYKFMWESNLLQHIQLQHPSTDNQEAEPTSTELPTTESQIFQCGQCPRKYNRKDRLTAHVKKCHTLGAVGPIVNAAKAAKTASVAKQHKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQNGHFETGDTVGKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00472482; iTF_00562595; iTF_00553831; iTF_00556638; iTF_00614317; iTF_00509231; iTF_00520762; iTF_00595375;
90% Identity
-
80% Identity
-