Dsia002849.1
Basic Information
- Insect
- Drosophila siamana
- Gene Symbol
- -
- Assembly
- GCA_035047445.1
- Location
- JAWNPP010000004.1:22623347-22627939[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 26 0.0018 0.11 12.9 2.0 1 23 215 237 215 237 0.96 2 26 0.002 0.12 12.7 1.7 1 23 243 265 243 265 0.98 3 26 0.059 3.6 8.1 0.4 2 23 299 321 298 321 0.93 4 26 0.003 0.18 12.1 5.3 1 23 396 419 396 419 0.95 5 26 0.53 32 5.1 1.1 2 22 426 446 425 446 0.95 6 26 0.45 27 5.3 0.4 1 20 455 474 455 476 0.93 7 26 2 1.2e+02 3.3 0.6 2 23 486 507 485 507 0.95 8 26 0.00041 0.024 14.9 0.5 1 23 588 611 588 611 0.96 9 26 0.0081 0.49 10.8 0.0 2 22 621 641 621 641 0.95 10 26 1 63 4.1 6.1 1 23 650 673 650 673 0.93 11 26 0.00037 0.022 15.0 0.4 2 23 700 721 699 721 0.97 12 26 9.9e-05 0.006 16.8 3.7 1 23 729 751 729 751 0.98 13 26 0.046 2.7 8.4 3.5 1 23 902 925 902 925 0.95 14 26 0.0073 0.44 10.9 0.4 2 22 933 953 932 953 0.95 15 26 0.012 0.75 10.2 0.4 1 23 962 985 962 985 0.93 16 26 2.4e-05 0.0015 18.7 3.5 1 23 1010 1032 1010 1032 0.97 17 26 0.00066 0.04 14.2 1.2 1 23 1039 1061 1039 1061 0.98 18 26 0.014 0.84 10.0 0.0 2 20 1088 1106 1087 1108 0.93 19 26 0.0062 0.37 11.2 2.3 1 23 1153 1176 1153 1176 0.96 20 26 0.02 1.2 9.6 1.1 1 23 1213 1236 1213 1236 0.96 21 26 0.00095 0.058 13.7 3.5 1 23 1259 1282 1259 1282 0.97 22 26 1.3e-05 0.00081 19.5 0.1 2 23 1310 1331 1309 1331 0.95 23 26 4.6e-05 0.0028 17.9 2.9 1 23 1337 1359 1337 1359 0.99 24 26 2.2e-06 0.00013 22.0 2.0 1 23 1365 1387 1365 1387 0.97 25 26 5.7e-08 3.5e-06 27.0 2.4 1 23 1393 1415 1393 1415 0.99 26 26 0.00096 0.058 13.7 0.2 1 21 1421 1441 1421 1445 0.91
Sequence Information
- Coding Sequence
- ATGTTGCCGACTGATATATGCCGTACTTGTGCGCTGCATAATGATAAATTGTTGGCGCTTTCAACACGCACCGGGAAATATGCGAATAAAAGTTTGTGCGATATTTTGCATGAGTTAACGCAAAATGATCCATTAATGGAACACTCCGATGACAATCTGCCGCAGTATCTATGTGACGACTGTTTGCGTAAGCTGGAAGATGCCTACGCATTTGTGTTGCAAGCCAGGCAAGTACACGAGCAGCTGTTGCACAAACTGCGTAAAGGATTGCAGTGTCTCGAAGAGCCACCAATTGACATCAACACCAATGACATAAAAACCGAATCTGACCTTGGCTTGGAACATATTGACAATGCTGCAACAGTACTGGAAGTTGGCTCTGAAGCGATTGTTGCAGCCTTGAAAATTCAACCGGAGTCCGAgagtgacagcgacagcaacgatGGCACATCAGCCACAGTTGAAGGCGACTCACTAGATTCGAAGACTCCGCAGCCAAGACGCAGCAATCGCAAAGCAAAACATGCCactgacagcgacaacgaagAGAATTCGGGAAATGTGAATTTAATGCCACAAAAGCGCCGACGCGGTCGCCCCGCGCGTTTTCCCAAAAAGGAAGCCGTTAACAAAGAAGGGCGACATGCTTGCGAAGTGTGTGGCAAGACATTCTCGTGGCACCGTGACATGCAACGCCATGCACGGATTCACTTCGAGCAGGCTGGGTATGAGTGCGACGCATGTGGCAAGCGATTTCTGCGCAAAGACAAATACACTTATCACTTGCGATCGCATGAGAAACGTCAGgccaagcaacaagcaacagcgcCGCAGCAGGGCAGGGAGTGGTGCTTTGCAGAACGTCTCTATAGCGCCGGGCGTATGCAGCGGGTCGAGTGCAAGCTGTGCGACTTGCAGTTCCAACGGATACAGGAACTGCGCGAACATCTAACTAACCAGCATGCCAACATTGAATCGCTGTCGCATCTCAGCATCAATAGCGATATTATCAAAGAACAATTTAAAGACCAACAGTTGAATCTGGACCAGATTAAACAACAGGTTTGCGCGGACATAGCAGCGGCCAGCGATCAATTGGATAAGTACTGTATTGTCACCAATGCGTATGGCTATGAACTCAGTCTGAATGATTCGGACGAAGAGTCAACTGTAGCAGCTCTGCCATACCAATGCTTGCGTTGCAATGTTTCATTTACACGCAAACATCACCTGATGCTACacacgctgcagcagcacactGAAACTCCTCTACAACGCTGCAATATTTGTCAAATCGGTTTTATGTGCCAGAATCTGCTGGAGCAGCATCAACGCACCCAGTGCCAGAATCAATTAAAACGTTATAGCTGTCCAAACTGTCCAGGCAAATTTATCTGGTTGCAGAATCTAAAGCGACACGCATGTTTAAAAACTCAACATCAAAGACAACACATCCAGTGCTGTCTCTGTGCTGAACAACTACAGAACATGTCAGCTCTACGCTCTCATTTGCTTATGCATGGTGATGGACACAGTGGCATTGACTTTGATCGAACTACTGCCTACTTTCGTTGTCATTACCCGAATGGAGTTACTTGCAGCCAAACGGAGCTCAGCATGCGTATTGCCAGCGATTTCGCGGTACAGGATTATGGGCAATACTTCAGTGCCTGCTCGGAGAGCGGTCGGGAGCTGGACTTCTTTGACTCGGACCCAGGTTCAAGCGATGCTGAGCAGCCAACCACAACCACCTCTGCATTGCATTCGTGTGCACTGTGTGGCATGGCCACAACACGACTAGCTCAACTGCAGAAGCATCAAGAAACCGATCACAGTGACGTTAAGAACTCATTGCCCAATGTGTGTGATCAATGTGGTTTTGGATTCGTGGCAGAATCATTGCTACAACAACATATTCGGCGGTGCTGTGGCAAGCGACATGCAAAATACCATTGCCAGCAGTGTAATCTACATTTCATATGGCAATCCAATTACGAGCATCACATGGCATTCAAGCACGAGATGGATTTAGAAGAGAACCATGAGCAGGCGCCTAATACAAGATTGCGAAGCAAACGTCAACAAGCCGCCAAATTGCAGTGCAATCAATGCGAAAAGGTCTTCATCTGGCCAAAGGATCTGACACGTCACAAGCGGATTCATCAGCCGCAGGCAACCGCACAGTTcgaatgcaatttttgtgaGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCCCATCTGCGTGTACACGGCGAACAGCAGCTGGACGCAACGACAGCTGCGAATGTCGATAATCTGGATGCAAGCATGTTACAGCGAATGCCTGCAGTGTTGGGCCAATTGTGTCGACCGAATGGATGCAAGCAGATCCAGTGCATGATCTGCCTGTCACAGCATACAAAGATCTCAGACTTAAGAGCGCATTTGGTTAAACACCAATTGAGCGTGGAGTTCTCAGGAGATCGTGCCAAACCGGAGAGCATTGCGAGCATTTGTCGAGGATTATATCCAGAGCAGATGGTGCCAATGAATAAGCAACAATTGATTGAACGCATACAGAGTGACTTGAGCACCGGCATTGAGATGGAAAGATTCGTTTCGATAACCAACGAGGCGGCGATTGAGCTTAGTCTTGACAGCAGTGAAACTGAGACGGATTCAGACTCTGCCGAGCCAGAAAGAACTGAAACTTTACGGCAATACAATTGTGATCTGTGTCATCTGAAGCTAGCACGCAAACATCAACTCTACGCAcatcagctgcaacaacacacTTGGCAAGAGGCGACGCTCATCTGCTCGTATTGCCAGGCCAAATTCATTAACGAGCAGTTGCTAGAACATCATTATCGAACGCTCTGTCGGAATGCGCAAAAACGTTTTCTTTGCCGCAAGTGCCCTTTACGCTTTCGCTGGCGCGACAACCTCAAGTTGCACATGGACGTAGCGCATCAAGAAGTGGCCGGAGAGCAGACGAGCTTGGGTCTTCAATTGACTGCGACAAGTCTGCTGCCTGTTGTCAGCTACGATTGCCACGTATGCAATCGCagctttaaaatgcaaaaggatCTTACACGTCACACCTTGATGCATGCCCAGGAATCGAGCATCTATCGGTGTCGCTGGTGTGCCCGTCGCTTCTATCGGGAGACCAATCTGCTGCAGCACATCGAACGCCATGGCATCAACGCCGTCCAGCTGCCATATGCCGAAGCGCTGCTCAATGCCAGCCGACATCCACATGGCAAGAAATGCATCGAATGCAAAGTGTGCGATGTTCGTTTTCCAACAATTGCTTCACTACGTGTCCATTTGGCATCCACGCCTGATGGAACTCATCATGATGTGAGCTCAATGCTCAACTACTCTATCACCAATCAGCTTGGCTATGAGCTGCATTTGGACGACTCGGAAACGGATGAGGAGGCCAAACCCCCAGGCATACCCAAGCACTACACTTGTGGCATGTGTCAGCTGCGCTGTGTGCGCAAGTATGAGCTCTATCAGCACCAACAGGCGATGCATCGCCTAGAACGCATTGCTGAGGGATGTGATCAGTGTATCTACAAGAGCGTTTCCCCTGATCTGATTGCCTATCATCGGCGTGTGCAGTGCGACAACACGGAGAAGCAATTTAAGTGTTCCAAATGCAGCTACAAGTTTATGTGGGAGTCGAACTTGGTGCAGCATATCCAGCTACAGCATCCAAGCAACGATAtccaggaggaggaggcggcaTCAGCTGAGTTGCCAACGACTGAATGCCAGATCTTTCAATGCGGTCAGTGTCCACGAAAGTACAACCGAAAGGATCGACTGACAGCACACGTTAAGAAGTGCCACATACCAGGCGCAGTTGGCGCAACAGGAAATGCAGCCAAAACTGCAAAGACCGCAACTGCTGCCAAACAGCATAAAAGTTTCCTTTGCGCCTTTTGCGGCAAGGCAGTAAGCTCCTCCTCAAATCTCATTATACACATCCGACGCCATACTGGGGAGAAGCCATTCAAGTGCGACTACTGCGACATGGCATTTCCTCGTTCCTCCGATCTGCAGTGCCATCGACGCACGCACACGGGAGAACGGCCCCACGTTTGCACGGTATGCCAAAAGGGTTTCGCGCGCTCCTACAAGCTACAGCAGCATATGCGCATTCATAATGGCGAACGTCCCTACAAATGTACCTATTGTGATAAGAGCTTCACCCAGTCCAACGACCTGACGCTTCATATTCGACGGCACACGGGCGAGCGGCCCTATCAATGTGAGACTTGTGGAGAGCGCTTTATTCAGGGGACAGCACTCAAGAATCATAGACTACAGAACGGGCATTTTGAAGCCGGCGATAGTGTGGCTAAAGATAATTAG
- Protein Sequence
- MLPTDICRTCALHNDKLLALSTRTGKYANKSLCDILHELTQNDPLMEHSDDNLPQYLCDDCLRKLEDAYAFVLQARQVHEQLLHKLRKGLQCLEEPPIDINTNDIKTESDLGLEHIDNAATVLEVGSEAIVAALKIQPESESDSDSNDGTSATVEGDSLDSKTPQPRRSNRKAKHATDSDNEENSGNVNLMPQKRRRGRPARFPKKEAVNKEGRHACEVCGKTFSWHRDMQRHARIHFEQAGYECDACGKRFLRKDKYTYHLRSHEKRQAKQQATAPQQGREWCFAERLYSAGRMQRVECKLCDLQFQRIQELREHLTNQHANIESLSHLSINSDIIKEQFKDQQLNLDQIKQQVCADIAAASDQLDKYCIVTNAYGYELSLNDSDEESTVAALPYQCLRCNVSFTRKHHLMLHTLQQHTETPLQRCNICQIGFMCQNLLEQHQRTQCQNQLKRYSCPNCPGKFIWLQNLKRHACLKTQHQRQHIQCCLCAEQLQNMSALRSHLLMHGDGHSGIDFDRTTAYFRCHYPNGVTCSQTELSMRIASDFAVQDYGQYFSACSESGRELDFFDSDPGSSDAEQPTTTTSALHSCALCGMATTRLAQLQKHQETDHSDVKNSLPNVCDQCGFGFVAESLLQQHIRRCCGKRHAKYHCQQCNLHFIWQSNYEHHMAFKHEMDLEENHEQAPNTRLRSKRQQAAKLQCNQCEKVFIWPKDLTRHKRIHQPQATAQFECNFCERKFHRKDGLKSHLRVHGEQQLDATTAANVDNLDASMLQRMPAVLGQLCRPNGCKQIQCMICLSQHTKISDLRAHLVKHQLSVEFSGDRAKPESIASICRGLYPEQMVPMNKQQLIERIQSDLSTGIEMERFVSITNEAAIELSLDSSETETDSDSAEPERTETLRQYNCDLCHLKLARKHQLYAHQLQQHTWQEATLICSYCQAKFINEQLLEHHYRTLCRNAQKRFLCRKCPLRFRWRDNLKLHMDVAHQEVAGEQTSLGLQLTATSLLPVVSYDCHVCNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRETNLLQHIERHGINAVQLPYAEALLNASRHPHGKKCIECKVCDVRFPTIASLRVHLASTPDGTHHDVSSMLNYSITNQLGYELHLDDSETDEEAKPPGIPKHYTCGMCQLRCVRKYELYQHQQAMHRLERIAEGCDQCIYKSVSPDLIAYHRRVQCDNTEKQFKCSKCSYKFMWESNLVQHIQLQHPSNDIQEEEAASAELPTTECQIFQCGQCPRKYNRKDRLTAHVKKCHIPGAVGATGNAAKTAKTATAAKQHKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCETCGERFIQGTALKNHRLQNGHFEAGDSVAKDN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00589669;
- 90% Identity
- -
- 80% Identity
- -