Basic Information

Insect: Drosophila ustulata
Gene Symbol: VEZF1_1
Assembly: GCA_035047365.1
Location: JAWNPT010000094.1:8314834-8319429[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0017 0.11 13.0 2.0 1 23 214 236 214 236 0.96

2 26 0.02 1.4 9.6 2.8 1 23 242 264 242 264 0.98

3 26 2.8 1.9e+02 2.8 0.9 2 23 298 320 297 320 0.92

4 26 0.00073 0.049 14.1 0.9 1 23 395 418 395 418 0.93

5 26 2 1.4e+02 3.3 0.7 2 22 425 445 424 445 0.94

6 26 8.3 5.6e+02 1.4 1.4 1 19 454 472 454 474 0.90

7 26 0.45 30 5.4 4.3 2 23 485 506 484 506 0.97

8 26 0.0009 0.061 13.8 0.2 1 23 587 610 587 610 0.93

9 26 0.022 1.5 9.5 0.0 1 22 619 640 619 640 0.95

10 26 0.43 29 5.4 2.5 1 23 649 672 649 672 0.92

11 26 0.00038 0.026 15.0 0.4 2 23 699 720 698 720 0.97

12 26 4.3e-05 0.0029 18.0 3.7 1 23 728 750 728 750 0.98

13 26 0.56 38 5.0 4.1 1 23 900 923 900 923 0.95

14 26 0.0025 0.17 12.4 2.2 2 23 931 952 930 952 0.96

15 26 0.013 0.86 10.2 0.4 1 23 960 983 960 983 0.93

16 26 1.5e-05 0.001 19.4 1.9 1 23 1008 1030 1008 1030 0.97

17 26 0.00068 0.046 14.2 1.2 1 23 1037 1059 1037 1059 0.98

18 26 0.07 4.7 7.9 0.1 2 21 1086 1105 1085 1106 0.93

19 26 0.0038 0.26 11.9 2.5 1 23 1151 1174 1151 1174 0.96

20 26 0.0047 0.32 11.6 1.1 1 23 1211 1234 1211 1234 0.96

21 26 0.00098 0.066 13.7 3.5 1 23 1257 1280 1257 1280 0.97

22 26 1.4e-05 0.00093 19.5 0.1 2 23 1308 1329 1307 1329 0.95

23 26 4.7e-05 0.0032 17.9 2.9 1 23 1335 1357 1335 1357 0.99

24 26 2.3e-06 0.00015 22.0 2.0 1 23 1363 1385 1363 1385 0.97

25 26 5.9e-08 4e-06 27.0 2.4 1 23 1391 1413 1391 1413 0.99

26 26 0.00099 0.067 13.7 0.2 1 21 1419 1439 1419 1443 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0017	0.11	13.0	2.0	1	23	214	236	214	236	0.96
2	26	0.02	1.4	9.6	2.8	1	23	242	264	242	264	0.98
3	26	2.8	1.9e+02	2.8	0.9	2	23	298	320	297	320	0.92
4	26	0.00073	0.049	14.1	0.9	1	23	395	418	395	418	0.93
5	26	2	1.4e+02	3.3	0.7	2	22	425	445	424	445	0.94
6	26	8.3	5.6e+02	1.4	1.4	1	19	454	472	454	474	0.90
7	26	0.45	30	5.4	4.3	2	23	485	506	484	506	0.97
8	26	0.0009	0.061	13.8	0.2	1	23	587	610	587	610	0.93
9	26	0.022	1.5	9.5	0.0	1	22	619	640	619	640	0.95
10	26	0.43	29	5.4	2.5	1	23	649	672	649	672	0.92
11	26	0.00038	0.026	15.0	0.4	2	23	699	720	698	720	0.97
12	26	4.3e-05	0.0029	18.0	3.7	1	23	728	750	728	750	0.98
13	26	0.56	38	5.0	4.1	1	23	900	923	900	923	0.95
14	26	0.0025	0.17	12.4	2.2	2	23	931	952	930	952	0.96
15	26	0.013	0.86	10.2	0.4	1	23	960	983	960	983	0.93
16	26	1.5e-05	0.001	19.4	1.9	1	23	1008	1030	1008	1030	0.97
17	26	0.00068	0.046	14.2	1.2	1	23	1037	1059	1037	1059	0.98
18	26	0.07	4.7	7.9	0.1	2	21	1086	1105	1085	1106	0.93
19	26	0.0038	0.26	11.9	2.5	1	23	1151	1174	1151	1174	0.96
20	26	0.0047	0.32	11.6	1.1	1	23	1211	1234	1211	1234	0.96
21	26	0.00098	0.066	13.7	3.5	1	23	1257	1280	1257	1280	0.97
22	26	1.4e-05	0.00093	19.5	0.1	2	23	1308	1329	1307	1329	0.95
23	26	4.7e-05	0.0032	17.9	2.9	1	23	1335	1357	1335	1357	0.99
24	26	2.3e-06	0.00015	22.0	2.0	1	23	1363	1385	1363	1385	0.97
25	26	5.9e-08	4e-06	27.0	2.4	1	23	1391	1413	1391	1413	0.99
26	26	0.00099	0.067	13.7	0.2	1	21	1419	1439	1419	1443	0.91

Sequence Information

Coding Sequence: atgctgcCCACCAATATATGCCGCACATGTGCGCTGCATAATGTAAAATTGCTGTCGCTTTCAACACGCACCGCGAAGTACGCAAATAAAAGTTTGTGCGACATTTTGCATGAATTGACACAAAATGATCCACTAATGGAACACTTGGATAACAATCTGCCGCAATATATATGCGACGACTGCTTGCGTAAGCTGGAAGATGCCTACGCCTTTGTGTTGCAAGTCAGACAAGTGCACGAGCAGCTGTTGCATAAGCTGCGCAAAAGATTGCAATGCCTGGATGAGCCTCCCATAGACATCGCCACGGATGATATCAAAACCGAAGCAGACCTTGCCTTGGATCACATCGATAATGCAGTAGCTTTAGATGTGGTTGCTAGTGAAGCGATTGTTGCAGCTTTTAAAATACAGCCCGAGTCGGAGACCGACAGCAACGATGGCGCAGAAGACGCGATTGATGAGGGCGATGTGCTGGACTTGAAGCCAGCGAAGCTGAGACGCAGCAACCGTAAAGCGAGAGCTGGCACTGACAGCGAGAATGAAGAGAGTGCTGAGAATTCGAACTTAATGCCACTTAAGCGTCGACGCGGACGTCCAGCGCGTGTACCCAAAAAGGAAGCCGTCAACAAAGACGGACGACACGCTTGCGAGGTTTGTGGCAAGACTTTCTCGTGGCATCGCGACATGCAACGCCACGCACGCGTTCATTTCGAGCAGGCTTCGTATGAGTGCGACACATGTGGCAAGCGCTTTCTGCGCAAGGACAAATATACTTTTCACTTGCGATCACACGAGAAACGCCAGGCTAAGCCACATGCAACAGCCCTGCAGCTGGGCAACGAGAGGCGCTATGCAGAGCGACTCTATAGCGCCGGGAGACTCAAGCGTATTGAGTGCAAGCTGTGCGACTTAAAGTGTCTGCGGATTGAGGAGTTGCGCGAGCATCTCACTAGTCAGCATGTCGGCATTGAATCATTGTCGCATCTCAACAGCGATAGCGATGTCGTCAGGGAACAGTTTGCCAGTCAAATGTCGAACCTGGAACTGATTAAAAAGCAAGTCTGCTCGGATATAGCAACGGCAAGTGATCAACTTGACAAGTACTGTATGGTGATCAATGCGCATGGCTATGAGCTAAGTCTATATGATTCGGACGAGGAGTTAGTTGGCGATACCGCGCCATATCAATGCTTGCCCTGCAGTCTTTCATTTACACGCAAATATAACCTGATGCGCCACACGCTGGAGGAGCACACTCAAACGCCTACTCAACGCTGCGACATTTGtcaaattggttttgtgtgcgAGAAACTCTTCGAGCAGCATCTACGTACCCAGTGCCAGAATCAACTGAAACGCCACAGCTGTCCAAACTGTCCAGGCAAATTTATCTGGCTGCAGAATCTTAAGCAACACTCGTGCTTTAAGGAACAGGATCAAGGTCGCCAATTGCAATGTTGTCTGTGTGATGAACGACTTCACAACATGTCGACTCTCCGCTCCCATCTGCTCAAGCATAGCGACGGTCTCAGCGGCATTAAGGCAGATCAATCTGCAGCCTACTTTCGTCGCAATTTTCCCGATGGAGTCACTTGTAGCCAAGCAGAGCTCAGCACGCGTATTGCGAGCGATTTCGCTGCACAGGATTATGGACAATATTTCAATGCCTGCTCAGGCAGCGGCCGGGAAATGGACTTCTTTGACTCGGATACGGATTTAAGTGATGCTGAACAGCCAACCACGTCCACGTCTGCTTTGCATTCATGTGCGGTGTGCGGCAAGGCTACAGCACGTCTAGCTCAACTGCTTAGGCATCAAGAGGAGCAGCACAGGGACGTTAAGAACGCATTGCCACATGTTTGTGCTAAATGTGGCTTGGGATTCGTAGCCGAACCTTTGCTCCAACGACATTTGCGTCGCAACTGCGGCAAGCGACATGCCAAATATCATTGCCTACTGTGTAATCTGCACTTCATCTGGCAATCCAACTACGAACGGCACATCGTGCTCAAGCACGAGGTGGACACGGAAGAGGACCGCGAGCAGGCACCCAACACCAGATTGAGAAGCAAACGCCAGCAAGCCGCCAAACTGCAGTGCAATCAGTGCGAGAAGGTCTTCATCTGGCCAAAGGATCTGACGCGTCACAAGCGCATTCATCAGCCGCAAACATCTGCACAGTTTGAATGCAGCTTCTGTGATCGCAAGTTCCATCGCAAGGATGGCCTGAAATCCCATCTGCGTGTACACGGCGAGCAGCAACTGGATGTGACGCTTGCAGCTGTCGATCATCTAGATGCAAGTGTATTACAACGAATGCCAGCAGTGCTCAGGCAATTTTGTCGTCCAAATGGCTGCAAACAGATCCAGTGCATGATCTGCCTGTCACAGCATACAAAAATCTCTGATTTAAGGGCGCATTTGGTTAAGCATCAGTTCAGCGTGAAGTTCACAGGGGAGCGAGCCAAGCCAGAGAGCATTGCAAGTATTTGCCGAGGACTATATCCGGAGCAGACGATGCCACTGGATGAGCAGCAGCTGATTGAACGCATACAAAGTGACTTGAGCAGGGGCATTGAACTGGAAAGGTTCGTTTCGATAACTAACGAGGCGGGCATTGAGCTCAGCCTTGACAGCAGCGAAACTGAAACGGACTCTGACTCTGCTGAATCGCAAAGAGCCACCAGTGGACGGCAATACAATTGTGATCTGTGCCATTTGAAGTTGACACGCAAACACCAAATCTATGCccatcagctgcagcagcatacTTGGCAAGAGGCGACGCTCATCTGTGCGCATTGCCAGGCCAAGTTTGTTAATGAGCAGTTGCTGGAGCACCATTATCGCACGCACTGCCGCAACTCCCAAAAGCGGTTTCTGTGTCGCAAGTGTCCGTTACGCTTTCGCTGGCGCGACAATCTCAAGTTGCACATGGACGTGGCACATCAAGAAGTGGCCGGAGAACCGACGGTCTTAGGCATTCCAGTGAGCGCGAGAAGCTTGCAGCCAGTTGTCAGCTACGATTGCCAGGAGTGCAATCGCAGCTTCAAAATGCAAAAGGATCTCACACGCCACACACTGATGCATGCACAGGAGTCGAGCATTTATCGCTGTCGCTGGTGTGCCCGCCGCTTCTATCGCGAGACCAATCTGCTGCAGCACATCGAACGTCACGGCATCAATGCCGCTCAGCTACCTTATGCCGAAGCCCTGCTCAACGCCAGCCGTCATCCGCATGGCCAGAAGAGCATCGAATGCAAAGTGTGCAATGTGCGCTTTCAAACGATTGCCTCACTACGTCTCCACTTGTTGTCCACGCCCAGTGGAAGTCATCACGATGTGGGCTCGATGCTCAACTACTCCATCACCAATCAGCTGGGCTACGAGCTGCACTTGGATGACTCGGAAACGGATGAGGAGGCCAAACCACCTGGCGTGCCCTTGCACTACACCTGTGGCATGTGTCAGCTGCGTTGTGTGCGCAAGTATGAGCTCTTTCAGCACCAACAGGCGATGCACCGACTGGAACGCATTGCCGTGGGCTGTGATCAGTGCATTTACAAGAGCGTTTCCCCTGATTTGATCGCCTATCATCGGCGTGTACAGTGCGACAACACAGAAAAGAAATTCAAGTGCTCCAAGTGTGACTACAAGTTTATGTGGGAGTCCAACTTGCTGCAGCACATTCAGCTGCAACATCCCAGGAATGACAaccaggaggaggaggaaacAACATCGATGGCGACAACGGCTGACAGCCAGATCTTTCAGTGCGGCCAGTGTCCACGAAAATACAACCGGAAGGATCGACTGACAGCACATGTTAAGAAGTGTCATGCACCTGGCGCAGTTGGCCCAACGGGTAGTGCAACCAAAGCAGCAAAGGCTGCAACTATTGCCAAGCAGCACAAAAGTTTCCTCTGTGCTTTTTGTGGCAAGGCTGTGAGTTCCTCCTCGAATCTCATCATTCACATCCGCCGCCACACCGGCGAGAAGCCATTCAAGTGCGACTACTGCGATATGGCCTTTCCGCGCTCCTCCGATCTGCAGTGCCATCGACGCACCCACACTGGAGAACGGCCCCATGTTTGCACCGTTTGCCAAAAGGGATTCGCTCGCTCCtacaagctgcagcagcacatGCGCATTCACAATGGCGAGCGTCCCTATAAATGTACCTATTGCGACAAGAGCTTCACACAGTCCAATGATCTGACGCTGCATATTCGAAGGCATACGGGCGAGCGACCTTATCAATGTGAAACCTGCGGGGAACGCTTTATTCAGGGTACAGCACTCAAGAATCATAGACTACAGAATGGGCATTTTGAGGCCGGAGATACCTTGGCAAAGGATAATTAA
Protein Sequence: MLPTNICRTCALHNVKLLSLSTRTAKYANKSLCDILHELTQNDPLMEHLDNNLPQYICDDCLRKLEDAYAFVLQVRQVHEQLLHKLRKRLQCLDEPPIDIATDDIKTEADLALDHIDNAVALDVVASEAIVAAFKIQPESETDSNDGAEDAIDEGDVLDLKPAKLRRSNRKARAGTDSENEESAENSNLMPLKRRRGRPARVPKKEAVNKDGRHACEVCGKTFSWHRDMQRHARVHFEQASYECDTCGKRFLRKDKYTFHLRSHEKRQAKPHATALQLGNERRYAERLYSAGRLKRIECKLCDLKCLRIEELREHLTSQHVGIESLSHLNSDSDVVREQFASQMSNLELIKKQVCSDIATASDQLDKYCMVINAHGYELSLYDSDEELVGDTAPYQCLPCSLSFTRKYNLMRHTLEEHTQTPTQRCDICQIGFVCEKLFEQHLRTQCQNQLKRHSCPNCPGKFIWLQNLKQHSCFKEQDQGRQLQCCLCDERLHNMSTLRSHLLKHSDGLSGIKADQSAAYFRRNFPDGVTCSQAELSTRIASDFAAQDYGQYFNACSGSGREMDFFDSDTDLSDAEQPTTSTSALHSCAVCGKATARLAQLLRHQEEQHRDVKNALPHVCAKCGLGFVAEPLLQRHLRRNCGKRHAKYHCLLCNLHFIWQSNYERHIVLKHEVDTEEDREQAPNTRLRSKRQQAAKLQCNQCEKVFIWPKDLTRHKRIHQPQTSAQFECSFCDRKFHRKDGLKSHLRVHGEQQLDVTLAAVDHLDASVLQRMPAVLRQFCRPNGCKQIQCMICLSQHTKISDLRAHLVKHQFSVKFTGERAKPESIASICRGLYPEQTMPLDEQQLIERIQSDLSRGIELERFVSITNEAGIELSLDSSETETDSDSAESQRATSGRQYNCDLCHLKLTRKHQIYAHQLQQHTWQEATLICAHCQAKFVNEQLLEHHYRTHCRNSQKRFLCRKCPLRFRWRDNLKLHMDVAHQEVAGEPTVLGIPVSARSLQPVVSYDCQECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRETNLLQHIERHGINAAQLPYAEALLNASRHPHGQKSIECKVCNVRFQTIASLRLHLLSTPSGSHHDVGSMLNYSITNQLGYELHLDDSETDEEAKPPGVPLHYTCGMCQLRCVRKYELFQHQQAMHRLERIAVGCDQCIYKSVSPDLIAYHRRVQCDNTEKKFKCSKCDYKFMWESNLLQHIQLQHPRNDNQEEEETTSMATTADSQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVGPTGSATKAAKAATIAKQHKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCETCGERFIQGTALKNHRLQNGHFEAGDTLAKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589669;
90% Identity: iTF_00520762;
80% Identity: -