Dnen019077.1
Basic Information
- Insect
- Drosophila neonasuta
- Gene Symbol
- -
- Assembly
- GCA_005889595.1
- Location
- MRUE01013994.1:4364-9194[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 26 0.0015 0.15 12.9 2.0 1 23 215 237 215 237 0.96 2 26 0.018 1.8 9.6 2.8 1 23 243 265 243 265 0.98 3 26 0.67 66 4.6 3.2 2 23 299 320 298 321 0.94 4 26 0.00029 0.028 15.2 4.3 1 23 396 419 396 419 0.94 5 26 1.1 1.1e+02 4.0 1.2 1 22 425 446 425 446 0.95 6 26 4.1 4.1e+02 2.1 0.9 1 19 455 473 455 476 0.89 7 26 0.33 32 5.6 3.0 1 23 485 507 485 507 0.97 8 26 0.0078 0.78 10.7 0.3 1 23 588 611 588 611 0.92 9 26 0.0014 0.14 13.0 0.1 1 22 620 641 620 641 0.95 10 26 2 2e+02 3.1 2.2 1 23 650 673 650 673 0.93 11 26 0.00033 0.033 15.0 0.4 2 23 700 721 699 721 0.97 12 26 0.00013 0.013 16.3 3.6 1 23 729 751 729 751 0.98 13 26 0.031 3.1 8.8 2.0 1 23 901 924 901 924 0.95 14 26 0.0046 0.46 11.4 0.9 2 22 932 952 931 952 0.95 15 26 0.025 2.5 9.1 0.3 1 23 961 984 961 984 0.93 16 26 1.3e-05 0.0013 19.4 1.9 1 23 1010 1032 1010 1032 0.97 17 26 0.00059 0.059 14.2 1.2 1 23 1039 1061 1039 1061 0.98 18 26 0.0031 0.3 12.0 0.0 2 21 1088 1107 1087 1108 0.94 19 26 0.0056 0.56 11.1 2.3 1 23 1153 1176 1153 1176 0.96 20 26 0.022 2.2 9.3 0.7 1 23 1213 1236 1213 1236 0.96 21 26 0.00086 0.085 13.7 3.5 1 23 1261 1284 1261 1284 0.97 22 26 1.2e-05 0.0012 19.5 0.1 2 23 1314 1335 1313 1335 0.95 23 26 0.00021 0.021 15.7 3.1 1 23 1341 1363 1341 1363 0.99 24 26 2e-06 0.0002 22.0 2.0 1 23 1369 1391 1369 1391 0.97 25 26 5.2e-08 5.1e-06 27.0 2.4 1 23 1397 1419 1397 1419 0.99 26 26 0.00087 0.086 13.7 0.2 1 21 1425 1445 1425 1449 0.91
Sequence Information
- Coding Sequence
- atgTTGCCGACTGATATATGCCGCACATGTGCGCTGCACAATGTTAAATTGTTGGCACTTTCAACACGCAACGCGAAATATGCGAATAAAAGTTGGTGCGACATTTTGTATGAATTAACACAAAATGATccCTTAATGGAACAGCTGGATGACAATCTACCTCAGTATCTATGTGATGACTGCTTACGTAAGCTGGAAGATGCTTACGCATTTGTGTTACAAGCTCGCCAGGTGCACGAGCAGCTATTGCATAAACTACACAAAAATTTGCAGTGCCTCGATGAGGCACCAATCGACATTGCAACGAATGAGATTAAGAGCGAAACAGATCTTGCTTTGGAGCAGATAGataatgcagcagcagcattggaTGTTGCTGGTGGGGAAGCGATTGCTGCAACTCTTAAAATACAGCCAGAGAGCGACAGTGACAGCAATGTTGGCAAAACTGAATCAGTTGAAGCCAGAGGCAACGTGCTAGACTTGAAGCCAACGCAGCTGAGACGCAGCAATCGCAAACCAAAACTTGCTACTGACAGTGAGAATGAAGAGACttcaaatttgaaagcaaTGCCGCTAAAGCGTCGTCGCGGTCGTCCAGCGCGTGTATCGAAAAACGAAGTCATCAACAAAGACGGACGACACGCCTGTGATGTGTGTGGCAAGACCTTCTCGTGGCACCGCGATATGCAACGACACGCACGCGTTCATTACGAGCAGGCTGCCTACGAGTGCGATACATGTGGCAAGCGTTTTTTACGCAAGGATAAATATACTTTCCATCTGCGATCGCATGAGAAACGCCAGGCCAAGCATGCACAAACAACTTTGCCGCAGGGCGACGAGTGGCGGTTTGCAGAGCGCCTTTATAGCTCGGCGCGTTTAAAGCGAATCGAGTGTAAGCTATGCGACTTGAAGTGCCAGCGAATTCAGGAGCTTCGCGAGCACCTCACGAATCACCATGTCAACATCGAGTCACTGTGCAATCTCAGCAATAATAGCGATGTTATAAGGGAACATTTTGACAGCCAAGCGTCGAATTTGGAACAGATAAAGCAACAGGTGTGCTCAGAGATTGCCACGGGAAGTGATCAACTTGACAAGTACTGTGTGATAATAAATGCCCATGGCTACGAACTCAGTTTAAACGATTCCGATGAAGAGTTAGCTGATACAACTCCGGCATATCAATGCTTGTCCTGCAATATTTCCTTTAAACGCAAACATCACCTTATTCGGCACACGCTAGAAGAGCACACTCAAACTCCTTTGCATCGTTGCAACACTTGTCAAATTGGGTTTGTGTGCGAGATTCTGCTGGAACAGCATCAACGCACCCAGTGTCAGAATCAATTGAAACGCCACAGCTGTCCAAACTGTCCAGGCAAATTCATCTGGCTGCAGAATCTAAAACAACACGGGTGCTCAAAGAAGACGGATCAAGAACGCCAATTCCAATGCTGTCTGTGTGATGAGCAACTACACAGCATGTCCGCTCTTCGGTCGCATCTGCTTCAGCATGGCGATGGAGGAAGCGGAATTGACGCTAATCAAACTGCTGCCTACTTTCGTTACCATTATCCAAATGGTGTGACTTGCAGTCAGGAAGAGCTCAGCACACGCATTTCAAATGACTTCAAGGTACAAGACTATGGGCAATACTTCAATGCGTGCTCAGGCAGCGGTCGCGAGTTGGATTTCTTTGCATCGGACACAGAACTAAGTGATGTTGAGCAGCTAACCACATCGACGTCTGCTCTACATTCATGTACGTTGTGTGGTGTAGCCACAGCTCGACTCGCTCAACTGCTGAGGCATCAAGAAGATCGTCACAGCGACGTCACGAACTATTTACCTCATGTTTGTAATAAATGTGGTTTGGGATTCGTGGCAGAGTCCTTACTGCAACAACATCTGCGGCGGATTTGCGACAAACGACATGCAATCTTTCATTGTGAGCCATGTAATCTGCATTTCATCTGGCAAACGAATTATGAGCGGCATATGGCGATCAAGCACGAGGTGGACACAGAGGAGGATCAAGAGCAGACGCACAATACTAGATTGAGAAGCAAACGACAACAAGCTgccaaattgcaatgcaatcaGTGTGAAAAGGTCTTTATCTGGCCAAAGGATCTAACGCGTCACAAGCGCATTCATCAGCCGCAGGCATCGGCACAGTTCGAGTGCAGTTTTTGTGAGCGCAAGTTTCATCGCAAGGATGGCCTAAAATCTCATCTTCGTGTACACGGCGAACAGCAACTAGAGGTGCCGCTCACTCCTGTTGAGCAAATGGATGCAAGTGTACTACAGCGAATGCCAGCAGTGTTGACACAGCTGTGTCGTCCGAACGGTTGCAAGCAGATCCAGTGTATGATCTGTCTATCGCAACACACAAAGATCTCTGATTTGCGAGCGCATTTAATGAAGCATCAGATAAGCGTGGAGTTCGTAGGGGAGCGAGCCAAACCGGAGAGCATTTCAAGCATTAGCCGCGGACTGTATCCGGAGCTGTCGACACCCCTGGATAAGCAGCAATTAATTGAACGCATACAGCGTGATCTGGGCAAAGGGATTGAGTTGGAGAGATTCGTTTCGATCACGAACGAGGCAGCGATTGAGCTCAGTCTTGACAGCAGTGAAACTGAAACGGATTCAGACTCTACCGAATCGCAACAAACTGACACTGGACGTCAATACAATTGTGACCTATGTCAAGTGCAGTTGACCCGCAAACATCAACTCTATGcccatcagctgcagcagcacacTTGGCAAGAGGCGACACTCGTCTGTTCACATTGCCAGGCCAAGTTCGTCAAtgagcagctgctggagcATCATTATCGTACTCTCTGTCGCAATGCTCAAAAGCGTTTTCTTTGCCGCAAGTGTCCACTGCGCTTTCGCTGGCGAGACAATCTCAAGTTGCACATCGACGTGGCACATCAAGAAGCGGCTGGATCACAGTCGAGTATTCAAGGCATTCAATTGAATACGACAAGTCTGTTGCCAATTGTGAGCTACGATTGCCAAGAGTGCAACCGCAgcttcaaaatgcaaaaggatCTCACTCGCCACACTCTAATGCATGCCCAGGACTCCAGTATTTATCGATGTCGGTGGTGTGCTCGCCGTTTCTATCGCGAAACCAATCTGCTGCAGCACATCGAACGCCATGGCATCAATGCCGCTCAGCTGCCATATGCCGAAGCCATCCTCAATGCCAGTCGCCATCCGCATGGTCAAAAGTGCATCCAATGCAAAGTGTGCGATATGCGCTTTCCAACAATTGCCTTATTGCGTACACACTTGATGTCCACGCCCAATGGTAGCCATCATGATGTTGGCTCGATGCTCAACTACTCCATCACTAATCAGCTGGGCTATGAGTTGCATTTGGACGACTCGGAAACGGATGAGGAAGGCAAACCTCCGGGAGTACCTACGCACTACACTTGCGGCATGTGCCAGCTGCGTTGTGTGCGCAAATATGAGCTCTACCAGCACCAGCAGGCAATGCATCGACTGGAACGCATTGCCGAGGGATGTGATAAATGCATCTACAAGAGCGTTTCCTCCGATCTGATTGCCTATCATCGTCGTGTGCTGTGTGATAACACAGAAAAGCAATTTAAGTGCGTTAAATGTGGCTACAAGTTCATGTGGGAGACGAACTTGTTGCAACACATCCAGCTGCAACATCCCAGCAACGACAATCAGCAGGTGGAGGAGATACCACAATCGCTGGAGTTGTCTGCAGCTGAAGGTCAGATCTTTCAGTGTGGCCAGTGTCCACGGAAATACAATCGCAAGGATCGGCTGACAGCACATGTTAAGAAGTGCCACGCACCAGGAGCCGTGAGCCCAACGATAGCAAATGCACCCAAAGCAGCAAAGGCTGCAGCAACTGTGGCTAAACAGCACAAAAGTTTCCTCTGTGCCTTTTGCGGCAAGGCGGTCAGCTCCTCATCGAATCTCATCATACACATACGTCGGCATACCGGCGAGAAGCCATTCAAGTGTGACTTCTGCGACATGGCGTTTCCTCGCTCCTCTGATCTGCAGTGCCATCGCCGCACTCACACTGGAGAACGGCCCCATGTTTGCACTGTGTGCCAAAAGGGATTCGCCCGCTCCtacaagctgcagcagcacatgCGTATTCACAATGGCGAACGTCCCTACAAATGTACCTATTGTGATAAGAGTTTCACCCAGTCCAATGATCTAACGTTGCACATACGACGGCACACGGGTGAGCGACCTTATCAATGTGAAACGTGCGGGGAACGCTTCATTCAGGGCACAGCACTCAAGAATCATAGACTACAGAACGGACATTTTGAAACCTCAGATTCCttggctaaaaataattag
- Protein Sequence
- MLPTDICRTCALHNVKLLALSTRNAKYANKSWCDILYELTQNDPLMEQLDDNLPQYLCDDCLRKLEDAYAFVLQARQVHEQLLHKLHKNLQCLDEAPIDIATNEIKSETDLALEQIDNAAAALDVAGGEAIAATLKIQPESDSDSNVGKTESVEARGNVLDLKPTQLRRSNRKPKLATDSENEETSNLKAMPLKRRRGRPARVSKNEVINKDGRHACDVCGKTFSWHRDMQRHARVHYEQAAYECDTCGKRFLRKDKYTFHLRSHEKRQAKHAQTTLPQGDEWRFAERLYSSARLKRIECKLCDLKCQRIQELREHLTNHHVNIESLCNLSNNSDVIREHFDSQASNLEQIKQQVCSEIATGSDQLDKYCVIINAHGYELSLNDSDEELADTTPAYQCLSCNISFKRKHHLIRHTLEEHTQTPLHRCNTCQIGFVCEILLEQHQRTQCQNQLKRHSCPNCPGKFIWLQNLKQHGCSKKTDQERQFQCCLCDEQLHSMSALRSHLLQHGDGGSGIDANQTAAYFRYHYPNGVTCSQEELSTRISNDFKVQDYGQYFNACSGSGRELDFFASDTELSDVEQLTTSTSALHSCTLCGVATARLAQLLRHQEDRHSDVTNYLPHVCNKCGLGFVAESLLQQHLRRICDKRHAIFHCEPCNLHFIWQTNYERHMAIKHEVDTEEDQEQTHNTRLRSKRQQAAKLQCNQCEKVFIWPKDLTRHKRIHQPQASAQFECSFCERKFHRKDGLKSHLRVHGEQQLEVPLTPVEQMDASVLQRMPAVLTQLCRPNGCKQIQCMICLSQHTKISDLRAHLMKHQISVEFVGERAKPESISSISRGLYPELSTPLDKQQLIERIQRDLGKGIELERFVSITNEAAIELSLDSSETETDSDSTESQQTDTGRQYNCDLCQVQLTRKHQLYAHQLQQHTWQEATLVCSHCQAKFVNEQLLEHHYRTLCRNAQKRFLCRKCPLRFRWRDNLKLHIDVAHQEAAGSQSSIQGIQLNTTSLLPIVSYDCQECNRSFKMQKDLTRHTLMHAQDSSIYRCRWCARRFYRETNLLQHIERHGINAAQLPYAEAILNASRHPHGQKCIQCKVCDMRFPTIALLRTHLMSTPNGSHHDVGSMLNYSITNQLGYELHLDDSETDEEGKPPGVPTHYTCGMCQLRCVRKYELYQHQQAMHRLERIAEGCDKCIYKSVSSDLIAYHRRVLCDNTEKQFKCVKCGYKFMWETNLLQHIQLQHPSNDNQQVEEIPQSLELSAAEGQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVSPTIANAPKAAKAAATVAKQHKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDFCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCETCGERFIQGTALKNHRLQNGHFETSDSLAKNN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00589669;
- 90% Identity
- iTF_00562595;
- 80% Identity
- -