Drob000047.1
Basic Information
- Insect
- Drosophila robusta
- Gene Symbol
- ken1
- Assembly
- GCA_004143805.1
- Location
- SCDV01000353.1:63351-65666[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.17 22 6.4 5.9 2 23 237 258 236 258 0.96 2 12 0.0034 0.42 11.7 1.2 1 23 264 289 264 289 0.92 3 12 0.00032 0.04 15.0 2.2 1 23 296 321 296 321 0.93 4 12 0.00022 0.028 15.5 4.1 1 23 331 353 331 353 0.97 5 12 0.00017 0.022 15.8 1.8 2 23 361 382 360 382 0.96 6 12 0.0058 0.73 11.0 0.5 1 23 388 410 388 410 0.97 7 12 0.023 2.9 9.1 1.9 1 23 416 439 416 439 0.97 8 12 0.015 1.9 9.7 4.1 1 23 445 467 445 467 0.95 9 12 0.0074 0.93 10.7 2.3 2 23 474 495 473 495 0.96 10 12 0.00014 0.018 16.1 0.8 1 23 576 599 576 599 0.96 11 12 0.0077 0.97 10.6 3.1 1 23 605 627 605 627 0.95 12 12 1.5e-05 0.0018 19.2 4.0 3 23 635 655 633 655 0.97
Sequence Information
- Coding Sequence
- ATGAGTGAGGGGAGCCAAATCTCCATTCATGCAATATGCCGTACTTGCTTATCGAAGTTGCAGCACGTTGCCGCCTACGATCTATTTGTGGTCCCAGGCCTGGCCAAGAAGCTGTGTGTCTGCACTTCCCTCTCCGTTGAGCAGCAGGATGGCTTCCCAAGGAACCTCTGCACCAATTGCTACACCCGACTAAACGATTTCCATGACTTCCAGAAGCAATGCGTGGACTCGGTTCAAAGGTTAAAGGACATGCTGGCCAACAGGTGCTTTACAATCCAGACCAGCCAAGTGGACAACTTTGCCGCGCCACAGGAATATCCGCAGGATGTGCCTGTCGAGGAAGAGGACCGCATTAACTTCGACCCGCTGCTGAATACCAAAAAAGAGATCATAGAGAACGAGGAGGATGTCTTCAAAATGCTCGAAGATGTCGACAAAGAGGTGGAGGACGTGGAAAAGGAGTCCTCCAGTGAAAGCGAGAACAAcgacaatgatgatgatgttgactttgaagccaacagcagcgaatCCGACGACGCCATGCCCCTGTCTCGTTTAAGAAGTGCCGCCAGAGTGACAAAGGCAGCGGACAAGCATGCAACTGATTCCTCCAGCTCTGGAACGGATGTAGATGCCGCAGTTGAACACTCCACGAAATCAAAGCGCAAACGCATTCCGCCCACGGAGCGCCATTTGCATCGCTTAATCGAGTGCCATATCTGCCACCAGAAGTTCAAGAAGGCGATTCGCTACGACGAGCACATGAAGCACCACAACGATCTGCTGCCCTTCCAGTGCAGTGTGGAGTCCTGCAAGAAGGGTTTCACGACTGCTGCAGGCCTGCGACATCATGTGGATCACGCGCACTCGGAACTCTGCGAACTGCACGCCTGCACTGTGGAAGGATGCGACAAGTCCTTCCCTCGGATGCGAATGCTGACCCATCACCTGAAAAAGGTACACAGCATTGCCAAGCCGGAGATCCGAGACCATCCATGCACGGAGTGCGACAAGGTGTTCCGCTGCCCAACGGCGCTCAAGAAACACATGTACAAGCACACGGGCGAGGAGCTGCCCATTTCGTGCAACATCTGCAACAAACGCTTCCATATAAACAGCGAACTCCGGGATCATCTCCTGCGCCATGCCGGCGTGAAGAACCACGTTTGTCCTTATTGCGGCGTGGGCAAAACCACTCGCCAGGAGTGGAACAAGCACATTCTGACGCACACCCGGGAGAAACAGTTCCAGTGCCGCCAGTGCGACCACGCCTCCCACAATAAACAGGCTCTGGCCAACCACGTCAAGGTGGTACACATGAAGATCAAGAACTTCGCCTGCCAGTACTGCGGCAAGACGTTCGGCAAATCGCACGCCTGCAAGATCCACGAGAGACTGCACACGGGCGAGAACTGTTGCGAGTGTAAGATCTGTGGCAAGATCTTCCTCTTCGAGAAGCGTTTGACTAAGCATTTGCAGATCCACGAGAAGCGCGAGGTACCAACGTCTGCGCAAGTCGACGAGAGTGGACAGAATGCTCAACAGTCGACAGAGACCGTGGATGCAAAGGCTGCGCTTGCAGCTCCTGCTGTCAGACCGAAGAATTCCCATAGAGTGGAGCGTGTGGACATATCCCAGCTGGCGGGCACCTCGGTCAATCCCATTCCATCTGTATCGGTGCCCTCGTGGTCGCCCCAGGTCAACTTCACCAAGAAGGAGGGCCAGCACATTTGCCCCGGCTGTGGCCGTGGCTTCAACCATATTGGCAACATGAAGCTGCACTACAAGGTCATTCACGAGAAGATCAAGGATTTTGCGTGTCGCTTCTGCCCCAAGCGGTTTGGCAAGGCGCAATATCTGCGCCATCACGAATACACGCACACGGGCGAGCGGCCGTACGGCTGCAAGATATGCGACAAGCACTTCAGCCACGGCTCATCGCTGCGCAAGCACATGATTTCGCACAACAGGCCGCCAAAAGTGCCCAAGGCTCCAAAAGCAACGGCCAAGACAAAGGAGCACCAAAGGCCGAAAATCGAACTGAACAAGCGGCCTGCAAGGAACTACGAACAGTACCAGGATCCAGCTGCAGAGCGGGCTGCCGCCACGGCTGAGCTGATGGCTCAGCAGCTCGAGGAGAGTGAAGCCAAACGTCGGGCGGAGGCCAAGACCCGAGAGATTCAGGAGGCCGCATGCGAGCAGCTTCAGAAGCTGCAGAAGGAGCAGCTGATCGAGAAGATATCCTACGACAGCTTTCAGGTGCAAAGGTCCGAGTCCGGGATAAGCGTGGATGCACTTAAAATAGATCAAGTCTAA
- Protein Sequence
- MSEGSQISIHAICRTCLSKLQHVAAYDLFVVPGLAKKLCVCTSLSVEQQDGFPRNLCTNCYTRLNDFHDFQKQCVDSVQRLKDMLANRCFTIQTSQVDNFAAPQEYPQDVPVEEEDRINFDPLLNTKKEIIENEEDVFKMLEDVDKEVEDVEKESSSESENNDNDDDVDFEANSSESDDAMPLSRLRSAARVTKAADKHATDSSSSGTDVDAAVEHSTKSKRKRIPPTERHLHRLIECHICHQKFKKAIRYDEHMKHHNDLLPFQCSVESCKKGFTTAAGLRHHVDHAHSELCELHACTVEGCDKSFPRMRMLTHHLKKVHSIAKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALANHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKREVPTSAQVDESGQNAQQSTETVDAKAALAAPAVRPKNSHRVERVDISQLAGTSVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKVPKAPKATAKTKEHQRPKIELNKRPARNYEQYQDPAAERAAATAELMAQQLEESEAKRRAEAKTREIQEAACEQLQKLQKEQLIEKISYDSFQVQRSESGISVDALKIDQV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00576571; iTF_00490978; iTF_00547534; iTF_00617106; iTF_00541972; iTF_00567739; iTF_00531157; iTF_00512944; iTF_00506323; iTF_00475420; iTF_00563382; iTF_00551068; iTF_00561269; iTF_00587640; iTF_00508571; iTF_00526783; iTF_00496078; iTF_00598356; iTF_00534783;
- 90% Identity
- iTF_00598356;
- 80% Identity
- -