Basic Information

Insect: Drosophila picticornis
Gene Symbol: ken1
Assembly: GCA_035043845.1
Location: JAWNMR010000122.1:8711906-8714233[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.16 9.6 6.8 6.3 3 23 238 258 236 258 0.96

2 12 0.044 2.7 8.5 1.0 1 23 264 289 264 289 0.92

3 12 0.0021 0.13 12.7 1.5 1 23 296 321 296 321 0.93

4 12 0.00027 0.017 15.5 4.1 1 23 331 353 331 353 0.97

5 12 0.0002 0.012 15.9 1.8 2 23 361 382 360 382 0.96

6 12 0.0072 0.45 11.0 0.5 1 23 388 410 388 410 0.97

7 12 0.053 3.2 8.3 2.6 1 23 416 439 416 439 0.97

8 12 0.019 1.2 9.7 4.1 1 23 445 467 445 467 0.95

9 12 0.0092 0.57 10.6 2.3 2 23 474 495 473 495 0.96

10 12 0.00017 0.011 16.1 0.8 1 23 580 603 580 603 0.96

11 12 0.0095 0.59 10.6 3.1 1 23 609 631 609 631 0.95

12 12 1.8e-05 0.0011 19.2 4.0 3 23 639 659 637 659 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.16	9.6	6.8	6.3	3	23	238	258	236	258	0.96
2	12	0.044	2.7	8.5	1.0	1	23	264	289	264	289	0.92
3	12	0.0021	0.13	12.7	1.5	1	23	296	321	296	321	0.93
4	12	0.00027	0.017	15.5	4.1	1	23	331	353	331	353	0.97
5	12	0.0002	0.012	15.9	1.8	2	23	361	382	360	382	0.96
6	12	0.0072	0.45	11.0	0.5	1	23	388	410	388	410	0.97
7	12	0.053	3.2	8.3	2.6	1	23	416	439	416	439	0.97
8	12	0.019	1.2	9.7	4.1	1	23	445	467	445	467	0.95
9	12	0.0092	0.57	10.6	2.3	2	23	474	495	473	495	0.96
10	12	0.00017	0.011	16.1	0.8	1	23	580	603	580	603	0.96
11	12	0.0095	0.59	10.6	3.1	1	23	609	631	609	631	0.95
12	12	1.8e-05	0.0011	19.2	4.0	3	23	639	659	637	659	0.97

Sequence Information

Coding Sequence: ATGAATGAGAGTAGGCAAAGCTCCATACACGCAATATGCCGCACTTGCTTGTCAAAACTGCAGCATGCTGGAGCATACGATTTGTTTGTGGTTCCAGGACTTGCAAAGAAACTGTATGTCTGCACTTCACTCTCCGTGCAGCAGCACGATGGCTTCCCGAGGAACCTTTGCCCCAGTTGCTACACCCGGCTAAACGACTTACATGATTTCCAGCAGAGATGCGTGGACTCTGTACAAAAGTTGAAGGACCTGCTAGCTAGCAATTACATTAGAATCCATACTGGCGAAGTTGACAGCTTTGATGTGCTAAGTGTGGGGGCGCCACAGGATGCTGATGTGCCTGTCGAGGAAGATGATAATATAAACTTTGACCCGCTACTTAAtaccaaaattgaaataattgaaaatgaggAGGATGTATTCAAAATGCTAGAAGATGTCGACAAAGACGCGGAGCAGGGAGATATGGAAAAGGAGTCCTCCAGTGACAACGAAAATGGCAATTATGATACTGAAGCGAATAACAGCGACTCCGACGACACCTTACCTCTATCCAGATTACGAAGTACTACCACAGAAGCTAAAGCAAAgaaggatgatgatgatgacgatgatgatgattatagATCGAGATTGGAATCGGATGTTAAGGCCGACGTTATAACCACGgttaaatcaaaatgcaagCGGATTCGGCCAGCTTTAATAGATTGTCACATTTGCCACCAGAAGTTCAAGAAAGAAATTCGCTACGAAGAGCACATGAAGCATCACAATGACCTATTGCCATTCCAGTGCACTGTGGAAACCTGCATGAAGGGTTTCACAACTGCCGCAGGTCTGCGACATCATGTGGATCATGCCCATTCGGAACTCTGCGAACTGCACGCCTGCACCGTGGAAGGATGTGACCAAGCATTCCCCCGCACTCGAATGCTCACACATCATCTAAAAAAGGTCCATCAAATTGCCAAGCCTGAGATTCGTGATCATCCTTGCACGGAATGCGACAAAGTGTTCCGTTGCCCAACAGCTCTGAAAAAACACATGTATAAGCACACTGGCGAGGAACTGCCGATTTCCTGTAACATCTGCAACAAGCGCTTTCACATAAACAGCGATCTCAGAGATCATCTCTTGCGCCATGCCGGTGTAAAGAATCATGTGTGCCCCTACTGCGGCGTCGGTAAAACCACTCGCCAAGAGTGGAACAAACACATTCTGACCCACACCAAGGAAAAACAGTTCCAGTGTCGCCAGTGCGATCATGCTTCCCACAACAAACAGGCTTTGTCCAATCACGTCAAGGTGGTTCATATGAAGATCAAAAACTTTGCGTGCCAGTATTGTGGCAAGACCTTTGGCAAATCGCATGCGTGCAAGATCCACGAGAGACTCCACACAGGCGAAAACTGCTGCGAGTGCAAGATTTGTGGCAAGATCTTCCTTTTCGAGAAGAGATTAACCAAGCATTTACAGATCCACGAGAAACGTGATATACCGTCTCCTGCAACCAATGTTAAGCCACAGGACAACGAGAGTCCGTTAAATGTGGGCCAGCAGTCAACTGAGCAGAACGATGCGAAGTCCATGACAGCAGTCCCCAAGCCGAAGAATTCTCATCGAGTTGAACGTGTGGATATATCGCAACTGGCTGGCACTTCTGTAAATCCAATATCATCGGTATCGGTGCCCTCGTGGTCGCCGCAGCTGAACTTCACAAAGAAGGAAGGCCAGCACATTTGTCCAGGATGTGGTCGCGGCTTCAACCACATCGGCAATATGAAATTGCACTATAAGGTGATACACGAAAAGATCAAGGATTTTGCGTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCTCAATATCTTCGACATCATGAATACACGCATACTGGTGAGAGGCCGTACGGCTGTAAGATATGCGATAAGCATTTTAGCCATGGGTCATCGCTAAGGAAGCATATGATTTCGCACAACCGACCACCAAAGGCCCCAAAGGCACTAAAGTTGCCGCCCAAGACAAAGGAGGAACAGCAGAGGCTAAAAATTGAGCTGAACAAGCGTCCGCCAAGAAACTATGAACAGTACCAGGATCCAGCTGCAGAACGGGCTGCAGCCACCGCTGAGTTGCTTGCCAAGCAGCTCGAAGAGGGTGAATCCAAACGTAAGGCTGAAGCCAAGGCTCGGACTATTCAAGAGGCAGCCTGTGAGCAGCTTCAGAAACTGCAGAAGGAGCAGCTGATTGAAAAGATATCCTCTGATAGCTTTCAAGTACAAAGGTCTGAGACCGGCATAAGCGTGGATGCACTCAAAgataatatataa
Protein Sequence: MNESRQSSIHAICRTCLSKLQHAGAYDLFVVPGLAKKLYVCTSLSVQQHDGFPRNLCPSCYTRLNDLHDFQQRCVDSVQKLKDLLASNYIRIHTGEVDSFDVLSVGAPQDADVPVEEDDNINFDPLLNTKIEIIENEEDVFKMLEDVDKDAEQGDMEKESSSDNENGNYDTEANNSDSDDTLPLSRLRSTTTEAKAKKDDDDDDDDDYRSRLESDVKADVITTVKSKCKRIRPALIDCHICHQKFKKEIRYEEHMKHHNDLLPFQCTVETCMKGFTTAAGLRHHVDHAHSELCELHACTVEGCDQAFPRTRMLTHHLKKVHQIAKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSDLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRDIPSPATNVKPQDNESPLNVGQQSTEQNDAKSMTAVPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQLNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKAPKALKLPPKTKEEQQRLKIELNKRPPRNYEQYQDPAAERAAATAELLAKQLEEGESKRKAEAKARTIQEAACEQLQKLQKEQLIEKISSDSFQVQRSETGISVDALKDNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589040;
90% Identity: iTF_00542659;
80% Identity: -