Basic Information

Insect: Drosophila novamexicana
Gene Symbol: ken1
Assembly: GCA_003285875.3
Location: NW:3025241-3027743[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.061 3.2 7.9 5.9 3 23 247 267 245 267 0.96

2 12 0.0011 0.06 13.4 1.4 1 23 273 298 273 298 0.92

3 12 2e-05 0.001 18.9 1.1 1 23 305 330 305 330 0.96

4 12 0.00025 0.013 15.4 4.1 1 23 340 362 340 362 0.97

5 12 0.0002 0.011 15.8 1.8 2 23 370 391 369 391 0.96

6 12 0.0066 0.35 11.0 0.5 1 23 397 419 397 419 0.97

7 12 0.018 0.95 9.6 2.2 1 23 425 448 425 448 0.97

8 12 0.017 0.92 9.6 4.1 1 23 454 476 454 476 0.95

9 12 0.0077 0.41 10.8 2.7 2 23 483 504 482 504 0.96

10 12 0.00016 0.0084 16.1 0.8 1 23 591 614 591 614 0.96

11 12 0.0087 0.46 10.6 3.1 1 23 620 642 620 642 0.95

12 12 1.6e-05 0.00088 19.1 4.0 3 23 650 670 648 670 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.061	3.2	7.9	5.9	3	23	247	267	245	267	0.96
2	12	0.0011	0.06	13.4	1.4	1	23	273	298	273	298	0.92
3	12	2e-05	0.001	18.9	1.1	1	23	305	330	305	330	0.96
4	12	0.00025	0.013	15.4	4.1	1	23	340	362	340	362	0.97
5	12	0.0002	0.011	15.8	1.8	2	23	370	391	369	391	0.96
6	12	0.0066	0.35	11.0	0.5	1	23	397	419	397	419	0.97
7	12	0.018	0.95	9.6	2.2	1	23	425	448	425	448	0.97
8	12	0.017	0.92	9.6	4.1	1	23	454	476	454	476	0.95
9	12	0.0077	0.41	10.8	2.7	2	23	483	504	482	504	0.96
10	12	0.00016	0.0084	16.1	0.8	1	23	591	614	591	614	0.96
11	12	0.0087	0.46	10.6	3.1	1	23	620	642	620	642	0.95
12	12	1.6e-05	0.00088	19.1	4.0	3	23	650	670	648	670	0.97

Sequence Information

Coding Sequence: atgaatGAGGAGAGGCAAATCTCCATTAACGAAATATGTCGAActtgtttatcaaaattgcAACACGTTGCAGTCTACGATCTGTTTGTGGTTCCGGGTCTGGCCAAGAAGCTATGTGTGTGCACTTCCCTATCGGTGGAGCAACATGATGGGTTCCCAAAAAGCCTTTGCTCCAATTGCTACACCCGTCTAAACGATTTACATGATTTTCAGAAGCAATGCGTGGACTCTCTTGATAAGTTGAGGGGCATGTTGGCCAACAACTACTTTACAATCCACACCAACCAGGCTAACAGTTTTGACGTGCTGCGTGTTGCACCACAGGATGTTGATGTGGCTATCGAAGAAGAAGACCGCATTAACTTTGACCCGCTCcttaatacaaaaattgagATAATTGAGAATGAGGAGGATGTTTTTAAAATGCTAGAAGATGTCGACAAAGAAGCGGAAGCGGAAGAGACGGATAAGGAGTCCTGTGAAAGCGAATACGAGAAAAATGATAACGATGTGGACTTTCAGGCGAATAGTAGCGATTCCGACGATGCCAGGCCCCTGTCTCAACTACGAACTGCTGCTGCggtattaaaaacaaatttaaagggCAGAAGTATGGCTGATGATGAAGGGAATTCCTCTAGCTCGGAATCGGACGTGGATAACGCAACTatatctaaagggaaaacgaAGCGCAAGCGAATTTCTGAGACTGAGCGACCTATGCAGCGTCTAATTGATTGTCACATTTGCCATCAAAAATTCAAGAAGGCGATTCGCTACGAGGAACACATGAAACATCACAACGATCTTTTACCATTCCAGTGTACTGTGGAAACCTGCAAAAAGGGTTTTACGACTGCCGCAGGTCTGCGACATCATGTGGATCACGCTCACTCGGAACTCTGCGAACTCTACGCCTGCACTGTAGAGGGATGCGGCAAGTCATTTCCTCGCACTCGTATGCTCACGCATCACCAGAAAAAGGTTCACAACATTATCAAGCCTGAGATCCGTGACCATCCCTGCACGGAATGTGATAAAGTCTTCCGATGTCCGACGGCGCttaaaaaacatatgtataagcATACTGGCGAGGAGCTGCCGATTTCCTGCAACATCTGCAACAAACGCTTTCACATAAACAGTGAACTTAGGGACCATCTATTGCGCCATGCCGGGGTGAAAAATCATGTTTGTCCTTATTGTGGCGTGGGCAAAACAACTCGACAGGAGTGGAATAAACACATATTGACGCACACCAAGGAAAAACAGTTCCAATGCCGACAGTGCGATCATTCTTCACACAACAAGCAGGCTTTAGCCAACCATGTCAATGTGGTTCACATGAAGATTAAGAACTTTGCCTGTCAGTACTGCGGCAAAACGTTTGGAAAATCGCACGCATGCAAGATTCACGAGAGACTTCACACTGGCGAGAATTGTTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTTTTCGAGAAGCGATTGAccaagcatttaaaaattcatgAGAAGCGCGAATTACCAGCGACTGATGCAAATGCACAAGTAGACGAAACAGGTCTGACTTCTTCGAATGTTAACCAGGAGTCCACAACACCGGTAGACGTAAAACCCGGGCCAGCATCGTTCGCTAAACCGAAGAAGTCGCATAGAGTTGAGCGTGTTGATATATCTCAGCTGGCCGGAACCTCTGTTAATCCAATTTCATCAGTTTCTGTGCCTTCCTGGTCGCCACAAGTGAACTTCACTAAGAAAGAAGGCCAGCACATTTGTCcaggctgtgggcgtggctttaACCACATTGGCAATATGAAGCTACACTACAAGGTGATACACGAAAAGATCAAAGATTTCGCGTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCCCAATATCTGCGTCATCATGAATATACGCATACAGGCGAGAGGCCTTATGGCTGCAAGATATGCGATAAACACTTTAGCCATGGCTCATCGCTGCGAAAGCATATGATTTCGCACAACAGACCACcgaaaattcaaaaatctCCAAAAACCACACCTCAGAAAAAAGAGCATCAGAGGCCAAAAATCGAACTTAACAAACGTCCCGCAAAGAATTATGAACAATACCAAGATCCAGCTGCGGAACGGGCTGCAGCTACTGCTGAACTGCTTGCTCAGCAACTCGAGGAGAGTGAGGCCAAACGAAGAGCGGAAGCTAAAACTCGTAGCATTCAAGAAGCTGCATGCGAGCAGCTGCAGAAGCTGCAAAGGGAGCAGCTGATCGAAAAGATATCCCTTGATAGCTTTCAAGTGGAAAGGTCGGAGGCTGGTATAGGCGTGGATGCTCTCAAGATAGATCATGTTTAA
Protein Sequence: MNEERQISINEICRTCLSKLQHVAVYDLFVVPGLAKKLCVCTSLSVEQHDGFPKSLCSNCYTRLNDLHDFQKQCVDSLDKLRGMLANNYFTIHTNQANSFDVLRVAPQDVDVAIEEEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKEAEAEETDKESCESEYEKNDNDVDFQANSSDSDDARPLSQLRTAAAVLKTNLKGRSMADDEGNSSSSESDVDNATISKGKTKRKRISETERPMQRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCKKGFTTAAGLRHHVDHAHSELCELYACTVEGCGKSFPRTRMLTHHQKKVHNIIKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHSSHNKQALANHVNVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLKIHEKRELPATDANAQVDETGLTSSNVNQESTTPVDVKPGPASFAKPKKSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKIQKSPKTTPQKKEHQRPKIELNKRPAKNYEQYQDPAAERAAATAELLAQQLEESEAKRRAEAKTRSIQEAACEQLQKLQREQLIEKISLDSFQVERSEAGIGVDALKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589040;
90% Identity: iTF_00475420;
80% Identity: -