Basic Information

Insect: Drosophila paramelanica
Gene Symbol: ken1
Assembly: GCA_035043915.1
Location: JAWNMO010000584.1:163448-165778[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.038 2.4 8.7 5.9 2 23 242 263 241 263 0.96

2 12 0.00043 0.027 14.8 0.9 1 23 269 294 269 294 0.92

3 12 0.00016 0.0098 16.2 2.1 1 23 301 326 301 326 0.93

4 12 0.00028 0.017 15.5 4.1 1 23 336 358 336 358 0.97

5 12 0.00022 0.014 15.8 1.8 2 23 366 387 365 387 0.96

6 12 0.0073 0.45 11.0 0.5 1 23 393 415 393 415 0.97

7 12 0.034 2.1 8.9 2.2 1 23 421 444 421 444 0.97

8 12 0.019 1.2 9.7 4.1 1 23 450 472 450 472 0.95

9 12 0.0093 0.58 10.6 2.3 2 23 479 500 478 500 0.96

10 12 0.00017 0.011 16.1 0.8 1 23 581 604 581 604 0.96

11 12 0.0096 0.6 10.6 3.1 1 23 610 632 610 632 0.95

12 12 6.8e-05 0.0042 17.4 4.3 3 23 640 660 638 660 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.038	2.4	8.7	5.9	2	23	242	263	241	263	0.96
2	12	0.00043	0.027	14.8	0.9	1	23	269	294	269	294	0.92
3	12	0.00016	0.0098	16.2	2.1	1	23	301	326	301	326	0.93
4	12	0.00028	0.017	15.5	4.1	1	23	336	358	336	358	0.97
5	12	0.00022	0.014	15.8	1.8	2	23	366	387	365	387	0.96
6	12	0.0073	0.45	11.0	0.5	1	23	393	415	393	415	0.97
7	12	0.034	2.1	8.9	2.2	1	23	421	444	421	444	0.97
8	12	0.019	1.2	9.7	4.1	1	23	450	472	450	472	0.95
9	12	0.0093	0.58	10.6	2.3	2	23	479	500	478	500	0.96
10	12	0.00017	0.011	16.1	0.8	1	23	581	604	581	604	0.96
11	12	0.0096	0.6	10.6	3.1	1	23	610	632	610	632	0.95
12	12	6.8e-05	0.0042	17.4	4.3	3	23	640	660	638	660	0.97

Sequence Information

Coding Sequence: atgaataaggggagCCAAATCTCCATACATACGATGTGCCGTACTTGCTTATCGCAATTACAGCACGTTCCCGCCTATGACCTGTTTGTGGTTCCGGGCCTGGCCAAGAAACTGTGTGTCTGCACCTCCCTCATAGTAGAGCAGCAGGATGGCTTTCCAAGGAACCTGTGCACCAATTGCTACACCCGACTGAACGAATTCCATGACTTTCAGAAGCAATGTGTTGACTCGGTGCAAAGGTTAAAGGACATGTTGAGCAACAAGTGCCTTACAATCCAGACTAACCAAGTGGACAGCTTCACTGTGCCTCAGGAATATCCACAGGATGTGCTTGTCGAGGAAGATGACCGTATTAACTTCGATCCGCTGCTAAATACCAAAATAGAGATCATTGAGAACGAGGAGGAGGTCTTTAAAATGATCGAGGATGTCGATAAAGAGGTGGAGGAGGAGGTAGAGATGGAGTCCCTTAGTGAAAACGAGGACAACAaagttgatgatgatgatgacctTGAAACAAACAGCAGCGAATCCGACGACGCCATGCCCCTCTCCCGTTTAAGATGTGCCGCCAGAGTGACAAAGGCAGTGGTCAAGCAAACAGCTGATGATGGAGCTGATTCCTCCAGCTCCGAAACGAACGCAGATGGCGCAGTTGAAgacacaacaaaatcaaaacaaaagcgcaTTTCCTCCGCTGAGCGTCAGTTGCATCGCTTGATCGAGTGTCACATTTGCCACCAGAAGTTCAAGAAGGCGATCCGATATGAGGAGCACATGAAGCACCACAACGATCTGTTACCCTTCCAGTGCAGTGTGGAGATCTGTAAGAAGGGTTTTACGACTGCCGCAGGCCTACGACATCATGTGGATCACGCGCACTCGGAACTTTGCCAACTGCACGCCTGCACTGTGGAAGGATGCGATAAGTCGTTCCCTCGCTTGCGAATGCTCACCCATCACCTGAAAAAGGTGCACAGCATTGCCAAGCCAGAGATCCGAGACCATCCCTGCACGGAGTGCGACAAGGTGTTCCGCTGCCCAACAGCTCTGAAGAAACATATGTACAAACACACGGGCGAGGAGCTTCCCATTTCTTGCAACATCTGCAACAAACGCTTCCACATAAATAGCGAACTCCGGGATCATCTGCTGCGCCATGCAGGTGTTAAGAACCACGTCTGTCCCTATTGTGGCGTGGGCAAAACCACTCGCCAGGAGTGGAACAAGCACATTCTGACGCATACCAGGGAGAAGCAGTTCAAGTGCCGCCAGTGCGACCACGCCTCCCACAACAAACAGGCGCTGGCCAACCACGTCAAGGTGGTGCACATGAAGATCAAGAACTTCGCCTGCCAGTACTGTGGCAAGACTTTTGGCAAGTCGCACGCCTGCAAGATTCACGAGAGGCTCCACACGGGCGAGAACTGCTGCGAGTGCAAGATCTGCGGCAAGATCTTTCTCTTCGAGAAGCGATTGACCAAGCATTTGCAGATCCACGAGAAGCGCGAGATACCAACGGCTGCGCCAGTCGATGACAGTGGACAGAATGCTCAACAGTCGTCGGAGCCAGAGCATGCAAAGTCCGCGCCAGCAGCTCCTGCTGTCAGGCCAAAGAGTTCCCATAGAGTTGAGCGGGTGGATATATCCCAGCTGGCGGGCACCTCGGTCAATCCCATACCATCTGTCTCAGTGCCCTCCTGGTCGCCGCAGGTCAACTTCACCAAGAAGGAGGGCCAACACATTTGCCCCGGCTGCGGGCGCGGCTTCAACCACATTGGCAATATGAAGCTTCACTACAAGGTCATTCACGAGAAGATCAAGGACTTTGCCTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCGCAGTATCTGCGACATCACGAATACACCCACACAGGCGAGCGGCCGTACGGCTGCAAGCTATGTGACAAGCACTTTAGCCACGGCTCATCTTTGCGGAAGCACATGATTTCGCATAATAGACCACCGAAAATGCCAAAGGCTCCAAAGACAACGGCCAAGTCAAAAGAGCACCAAAGGCCAAAAATCGAATTGAACAAGCGGCCAGCAAGGAACTACGAACAGTATCAAGACCCTGCTGCCGAACGGGCGGCCGCAACGGCTGAGCTGATGGCTCAGCAGCTCGAGGAGATTGAAGCCAAGCGTAGGGCGGAGGCCAAAACCCGAGAGATTCAGGAGGCCGCATGCCAACAGCTTCAGAAGCTGCAGAAGGAGCAGCTCATCGAGAAGATATCCTCCGACAGCTTTCAAGTGCAAAGGTCCGAGTCCGGCATAAATGTGGATGCACTTAAAACAGATCATGTTTAA
Protein Sequence: MNKGSQISIHTMCRTCLSQLQHVPAYDLFVVPGLAKKLCVCTSLIVEQQDGFPRNLCTNCYTRLNEFHDFQKQCVDSVQRLKDMLSNKCLTIQTNQVDSFTVPQEYPQDVLVEEDDRINFDPLLNTKIEIIENEEEVFKMIEDVDKEVEEEVEMESLSENEDNKVDDDDDLETNSSESDDAMPLSRLRCAARVTKAVVKQTADDGADSSSSETNADGAVEDTTKSKQKRISSAERQLHRLIECHICHQKFKKAIRYEEHMKHHNDLLPFQCSVEICKKGFTTAAGLRHHVDHAHSELCQLHACTVEGCDKSFPRLRMLTHHLKKVHSIAKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFKCRQCDHASHNKQALANHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKREIPTAAPVDDSGQNAQQSSEPEHAKSAPAAPAVRPKSSHRVERVDISQLAGTSVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKLCDKHFSHGSSLRKHMISHNRPPKMPKAPKTTAKSKEHQRPKIELNKRPARNYEQYQDPAAERAAATAELMAQQLEEIEAKRRAEAKTREIQEAACQQLQKLQKEQLIEKISSDSFQVQRSESGINVDALKTDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589040;
90% Identity: iTF_00541972;
80% Identity: -