Basic Information

Insect: Drosophila littoralis
Gene Symbol: ken1
Assembly: GCA_018903485.1
Location: JAEIGF010000408.1:6659254-6661593[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.062 3.9 7.9 5.9 3 23 240 260 238 260 0.96

2 12 0.0011 0.072 13.4 1.4 1 23 266 291 266 291 0.92

3 12 4.5e-05 0.0028 17.8 1.3 1 23 298 323 298 323 0.96

4 12 0.00025 0.016 15.4 4.1 1 23 333 355 333 355 0.97

5 12 0.0002 0.013 15.8 1.8 2 23 363 384 362 384 0.96

6 12 0.0067 0.42 11.0 0.5 1 23 390 412 390 412 0.97

7 12 0.018 1.1 9.6 2.2 1 23 418 441 418 441 0.97

8 12 0.018 1.1 9.6 4.1 1 23 447 469 447 469 0.95

9 12 0.0078 0.49 10.8 2.7 2 23 476 497 475 497 0.96

10 12 0.00016 0.01 16.1 0.8 1 23 584 607 584 607 0.96

11 12 0.0089 0.55 10.6 3.1 1 23 613 635 613 635 0.95

12 12 1.7e-05 0.0011 19.2 4.0 3 23 643 663 641 663 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.062	3.9	7.9	5.9	3	23	240	260	238	260	0.96
2	12	0.0011	0.072	13.4	1.4	1	23	266	291	266	291	0.92
3	12	4.5e-05	0.0028	17.8	1.3	1	23	298	323	298	323	0.96
4	12	0.00025	0.016	15.4	4.1	1	23	333	355	333	355	0.97
5	12	0.0002	0.013	15.8	1.8	2	23	363	384	362	384	0.96
6	12	0.0067	0.42	11.0	0.5	1	23	390	412	390	412	0.97
7	12	0.018	1.1	9.6	2.2	1	23	418	441	418	441	0.97
8	12	0.018	1.1	9.6	4.1	1	23	447	469	447	469	0.95
9	12	0.0078	0.49	10.8	2.7	2	23	476	497	475	497	0.96
10	12	0.00016	0.01	16.1	0.8	1	23	584	607	584	607	0.96
11	12	0.0089	0.55	10.6	3.1	1	23	613	635	613	635	0.95
12	12	1.7e-05	0.0011	19.2	4.0	3	23	643	663	641	663	0.97

Sequence Information

Coding Sequence: ATGAATGAGGAGAGGCAAATCTCCATAAACGAAATATGTCGCACTTGTTTATCAAAATTGCAACACGTTGCAGCCTACGATCTGTTTGTGGTGCCGGGTCTGGCCAAGAAGCTCTGTGTGTGCACTTCCCTCTCGGTGGAGCAACACGATGGGTTCCCAAAAAACCTTTGCGCCAATTGTTACACCCGTCTAAACGATTTACATGATTTTCAGAAGCAATGCGTGGACTCTCTTGATAAGTTGAAGGGCATGTTGGCCAACAACTACTTTACCATCCGGACCAACCAGGCTGATAGTTTTGACGTGCTGCGTGTTGCACCACAGGATGTTGATGTGGCTATCGCAGAAGAAGAAGACCGCATTAACTTTGACCCACTCCTTAATACAAAAATTGAGATAATTGAGAATGAGGAGGATGTTTTTAAAATGCTAGAAGATGTCGATAAAGAAGCGAAAGAGACTGAGAAGGAGTCCTCCTGTGAAAGCGGATACGAGAAAAATGATAACGCTGTGGACTCTCAGGCGGATTGTAGCGACTCCGACGATGCCAGGCCCCTGTCTCATCTACGAACTGCTGCTAAGGGCAAGAAAATGGCTGATGACGATGAGAATTCCTCTAGCTCCGAATCGGGCGTGGATAACACAAATGTATCTAAAGGGAAATCAAAGCGCAAGCGAATTTCTGCGTCTGAGCGACCCATGCAGCGTCTCATCGACTGTCACATTTGCCATCAAAAATTCAAGAAGGCAATTCGCTACGAGGAACACATGAAGCATCACAACGATCTTTTACCATTCCAGTGCACTGTGGAAACCTGCAAGAAGGGCTTTACGACTGCCGCAGGTCTGCGGCATCATGTGGATCACGCTCACTCAGAACTCTGCGAACTCTACGCCTGCACCGTAGAAGGATGCGACAAGTCGTTTCCTCGTACTCGTATGCTCACGCATCACCAGAAGAAGGTTCACAACATTATCAAGCCCGAGATACGTGACCATCCCTGCACGGAATGTGATAAAGTCTTCCGATGTCCAACGGCGCTTAAGAAACATATGTATAAGCATACTGGCGAGGAGCTGCCGATTTCCTGCAACATCTGCAACAAACGGTTTCACATAAACAGTGAACTTAGGGACCATCTTCTGCGACATGCCGGCGTGAAAAACCATGTTTGTCCATACTGCGGAGTGGGTAAAACAACTCGACAGGAGTGGAACAAGCACATATTGACGCACACCAAGGAGAAACAGTTCCAATGCCGACAGTGCGATCATTCCTCCCACAACAAGCAGGCTTTAGCCAATCATGTGAATGTGGTTCACATGAAGATTAAGAACTTTGCCTGCCAGTATTGCGGGAAAACGTTTGGAAAATCGCACGCCTGCAAGATCCACGAGAGACTTCACACTGGCGAAAATTGCTGCGAGTGCAAGATCTGTGGTAAGATCTTCCTTTTTGAGAAGAGATTGACCAAACATTTAAAAATTCATGAGAAGCGCGAGCTACCAGCGACTAATGCAAATGCACAACTAGACGAAACAGGTCAGACTTCTTCGAATGTTAACCAGGAGTCCACAACACCGCTAGACGTAAAACCCGGGCCAGCATCTTTCGCTAAACCGAAGAAGTCGCATAGAGTTGAGCGTGTTGATATATCTCAGCTGGCCGGAACCTCTGTTAATCCAATTTCATCGGTGTCTGTGCCTTCCTGGTCCCCACAAGTGAACTTCACAAAGAAAGAGGGCCAGCACATTTGTCCGGGCTGTGGGCGTGGCTTCAACCACATTGGCAATATGAAGCTGCACTATAAGGTGATACACGAAAAGATCAAAGATTTCGCGTGTCGCTTCTGCCCCAAGCGCTTTGGCAAGGCCCAATATCTACGTCATCATGAATATACGCACACCGGCGAGAGGCCGTATGGCTGTAAGATATGCGATAAACATTTTAGCCATGGTTCATCGCTGCGAAAGCATATGATTTCCCACAACAGACCACCAAAAGTTCAGAAAGCTCCAAAAACCACAGCTCAGAGAAAAGAGCATCAGAGGCCAAAAATCGAACTTAACAAGCGACCCGCAAAGAATTACGAGCAATACCAGGATCCTGCTGCGGAACGCGCTGCAGCTACTGCGGAACTGCTTGCTCAGCAACTCGAGGAGAGTGAGGCCAAACGAAGAGCGGAAGCTAAAGCTCGCAGGATTCAAGAAGCTGCATGCGAACAGCTGCAGAAGCTGCAAAAGGAGCAGCTGATCGAAAAGCTATCCCTCGATAGCTTTCAAGTGGAAAGGTCGGAAGCTGGTCTAAACGTGGATGCTCTCAAAATAGATCATGTTTGA
Protein Sequence: MNEERQISINEICRTCLSKLQHVAAYDLFVVPGLAKKLCVCTSLSVEQHDGFPKNLCANCYTRLNDLHDFQKQCVDSLDKLKGMLANNYFTIRTNQADSFDVLRVAPQDVDVAIAEEEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKEAKETEKESSCESGYEKNDNAVDSQADCSDSDDARPLSHLRTAAKGKKMADDDENSSSSESGVDNTNVSKGKSKRKRISASERPMQRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCKKGFTTAAGLRHHVDHAHSELCELYACTVEGCDKSFPRTRMLTHHQKKVHNIIKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHSSHNKQALANHVNVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLKIHEKRELPATNANAQLDETGQTSSNVNQESTTPLDVKPGPASFAKPKKSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKVQKAPKTTAQRKEHQRPKIELNKRPAKNYEQYQDPAAERAAATAELLAQQLEESEAKRRAEAKARRIQEAACEQLQKLQKEQLIEKLSLDSFQVERSEAGLNVDALKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589040;
90% Identity: iTF_00475420;
80% Identity: -