Basic Information

Insect: Drosophila lacicola
Gene Symbol: ken1
Assembly: GCA_035045355.1
Location: JAWNPB010000133.1:11625969-11628323[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.072 4.9 7.9 5.9 3 23 245 265 243 265 0.96

2 12 0.0013 0.091 13.4 1.4 1 23 271 296 271 296 0.92

3 12 5.2e-05 0.0036 17.8 1.3 1 23 303 328 303 328 0.96

4 12 0.0003 0.02 15.4 4.1 1 23 338 360 338 360 0.97

5 12 0.00023 0.016 15.8 1.8 2 23 368 389 367 389 0.96

6 12 0.0078 0.53 11.0 0.5 1 23 395 417 395 417 0.97

7 12 0.021 1.4 9.6 2.2 1 23 423 446 423 446 0.97

8 12 0.021 1.4 9.6 4.1 1 23 452 474 452 474 0.95

9 12 0.0091 0.62 10.8 2.7 2 23 481 502 480 502 0.96

10 12 0.00019 0.013 16.1 0.8 1 23 589 612 589 612 0.96

11 12 0.01 0.7 10.6 3.1 1 23 618 640 618 640 0.95

12 12 2e-05 0.0013 19.1 4.0 3 23 648 668 646 668 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.072	4.9	7.9	5.9	3	23	245	265	243	265	0.96
2	12	0.0013	0.091	13.4	1.4	1	23	271	296	271	296	0.92
3	12	5.2e-05	0.0036	17.8	1.3	1	23	303	328	303	328	0.96
4	12	0.0003	0.02	15.4	4.1	1	23	338	360	338	360	0.97
5	12	0.00023	0.016	15.8	1.8	2	23	368	389	367	389	0.96
6	12	0.0078	0.53	11.0	0.5	1	23	395	417	395	417	0.97
7	12	0.021	1.4	9.6	2.2	1	23	423	446	423	446	0.97
8	12	0.021	1.4	9.6	4.1	1	23	452	474	452	474	0.95
9	12	0.0091	0.62	10.8	2.7	2	23	481	502	480	502	0.96
10	12	0.00019	0.013	16.1	0.8	1	23	589	612	589	612	0.96
11	12	0.01	0.7	10.6	3.1	1	23	618	640	618	640	0.95
12	12	2e-05	0.0013	19.1	4.0	3	23	648	668	646	668	0.97

Sequence Information

Coding Sequence: ATGAATGAGGAGAGGCAAATCTCCATAAACGAAATATGTCGCACTTGTTTATCAAAATTGCAACACGTTGCAGCCTACGATCTGTTTGTGGTTCCGGGCCTGGCCAaaaagctgtgtgtgtgcacttccCTGTCGGTGGAGCAACACGATGGGTTCCCAAAAAGCCTTTGCTCCAATTGCTACACCCGTCTAAACGATTTACATGATTTTCAGAAGCAATGCGTGGACTCTCTTGATAAGTTGAAGGGCATGTTGGCCAACAATTACTTTACAATCCAGACCAACCAGGCTAACAACTTCGACGTGCTGCGTGTTGCACCACAGGATATTGATGTGGCTATCGAAGAAGAAGACCGCATTAACTTTGACCCGCTccttaatacaaaaattgagaTAATTGAGAATGAGGAGgatgtttttaaaatgttagaaGATGTCGACAAAGAAGCGGAGGAGACGGAGGAGTCCTCCTGTGAAAGCGAATACGAGAAAAATGATAACGATGTGGACTTTCAGGCGAATAGTAGCGACTCCGACGACGCCAGGCCTCTGTCTCATCTACGAACTGCTGCTGTGGTAGTACAAGCAAATTCAAAGGGCAAAAATATGGCTGATGATGAAGAGAATTCCTCTAGCTCTGAATCGGGCGTAGATAACGCAAATATATCTAACAAGAAATCGAAGCGCAAGCAAATTTCTACGTCTGAGCGACCGATGCAGCGTCTCATCGACTGTCACATTTGCCATCAAAAATTCAAGAAGGCAATTCGCTACGAGGAGCACATGAAGCATCACAACGATCTTTTACCATTCCAGTGTACTGTGGAAACCTGCAAAAAGGGTTTTACGACTGCCGCAGGTCTGCGACATCATGTGGATCACGCTCACTCAGAACTCTGCGAACTCTACGCCTGCACTGTAGAAGGATGCGACAAGTCATTTCCTCGTACTCGTATGCTCACGCATCACCAGAAAAAGGTTCACAACATTATCAAGCCTGAGATCCGTGACCATCCCTGCACCGAATGTGATAAAGTCTTCCGATGTCCAACGGCGCttaaaaaacatatgtataaacatacTGGCGAGGAGCTGCCGATTTCCTGCAACATCTGCAACAAACGCTTTCACATAAACAGTGAACTTAGGGACCATCTATTGCGCCATGCCGGCGTGAAAAACCATGTCTGTCCATACTGCGGAGTCGGCAAGACAACTCGACAGGAGTGGAATAAACACATATTGACGCACACCAAGGAAAAACAGTTCCAATGCAGACAGTGCGATCATTCCTCCCACAACAAGCAGGCTTTGGCCAATCATGTCAATGTGGTTCATATGAAGATTAAGAACTTTGCCTGTCAGTACTGCGGTAAAACCTTTGGAAAATCGCACGCCTGCAAGATCCACGAGAGACTTCACACTGGCGAAAATTGCTGCGAGTGCAAAATCTGTGGTAAGATCTTCCTTTTCGAGAAGAGATTGAccaagcatttaaaaattcatgaGAAGCGCGAGTTACCAGCGACTAATGTAAATGTACAGGTCGACGAGACAGGTCAGAATTCTTCAATTGTTAACCAGGAGTCTACAACACCGGTAGACGTAAAACCGGGGCCCGCATCTATCGCTAAAGCGAAGAAGTCGCATAGAGTTGAGCGTGTTGATATATCTCAACTGGCCGGAACCTCTGTTAATCCAATATCATCAGTTTCTGTGCCTTCCTGGTCCCCACAAGTGAACTTCACAAAGAAAGAAGGCCAGCACATTTGTCcaggctgtgggcgtggcttcAACCACATTGGGAATATGAAACTACACTATAAGGTGATACACGAAAAGATCAAAGATTTTGCGTGCCGCTTCTGCCCCAAGCGCTTTGGCAAGGCCCAATATCTACGTCATCATGAATATACGCATACAGGCGAGAGGCCGTATGGCTGTAAAATATGCGATAAACATTTTAGCCACGGCTCATCGCTGCGAAAGCATATGATTTCACACAACAGACCaccaaaaattcaaaaagctCCAAAAACCACACCTCAGAAAAAAGAGCATCAGAGGCCAAAAATCGAACTTAACAAACGTCCCGCAAAGAATTATGAACAGTACCAGGATCCTGCTGCGGAACGGGCTGCAGCTACTGCTGAACTGCTTGCTCAGCAACTCGAGGAGAGTGAAGCCAAACGAAGAGCGGAAGCTAAAACTCGTAGGATTCAAGAAGCTGCATGTGAGCAGCTTCAGAAGCTGCAAAAGGAACAGCTTATCGAAAAGATATCTCTTGATAGCTTTCAAGTGGAAAGGACTGAGGCTGGTATAAGCGTGGATGCTCTTAAAATGGATCATGTTTGA
Protein Sequence: MNEERQISINEICRTCLSKLQHVAAYDLFVVPGLAKKLCVCTSLSVEQHDGFPKSLCSNCYTRLNDLHDFQKQCVDSLDKLKGMLANNYFTIQTNQANNFDVLRVAPQDIDVAIEEEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKEAEETEESSCESEYEKNDNDVDFQANSSDSDDARPLSHLRTAAVVVQANSKGKNMADDEENSSSSESGVDNANISNKKSKRKQISTSERPMQRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCKKGFTTAAGLRHHVDHAHSELCELYACTVEGCDKSFPRTRMLTHHQKKVHNIIKPEIRDHPCTECDKVFRCPTALKKHMYKHTGEELPISCNICNKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHSSHNKQALANHVNVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLKIHEKRELPATNVNVQVDETGQNSSIVNQESTTPVDVKPGPASIAKAKKSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFSHGSSLRKHMISHNRPPKIQKAPKTTPQKKEHQRPKIELNKRPAKNYEQYQDPAAERAAATAELLAQQLEESEAKRRAEAKTRRIQEAACEQLQKLQKEQLIEKISLDSFQVERTEAGISVDALKMDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589040;
90% Identity: iTF_00475420;
80% Identity: -