Basic Information

Insect: Drosophila lowei
Gene Symbol: hang
Assembly: GCA_008121275.1
Location: CM017781.1:56127482-56141338[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.29 21 5.7 1.0 3 23 572 593 571 593 0.93

2 17 0.18 14 6.3 2.7 3 22 701 720 699 720 0.89

3 17 0.00062 0.046 14.1 3.3 1 22 824 845 824 847 0.90

4 17 0.071 5.3 7.6 0.1 2 21 859 878 858 879 0.93

5 17 0.00072 0.054 13.8 0.2 2 23 1015 1037 1014 1037 0.95

6 17 0.0021 0.15 12.4 0.1 1 23 1045 1068 1045 1068 0.96

7 17 0.00027 0.02 15.2 0.2 2 23 1154 1175 1153 1175 0.97

8 17 0.0003 0.022 15.1 2.9 2 23 1280 1302 1279 1302 0.97

9 17 0.023 1.7 9.1 0.2 2 23 1311 1333 1310 1333 0.95

10 17 0.0046 0.34 11.3 0.2 1 23 1346 1369 1346 1369 0.97

11 17 0.00013 0.0096 16.2 1.1 1 23 1450 1472 1450 1472 0.99

12 17 0.002 0.15 12.4 0.9 1 23 1480 1503 1480 1503 0.96

13 17 0.36 27 5.4 0.5 2 19 1511 1528 1510 1529 0.92

14 17 3.3e-05 0.0025 18.1 1.4 3 23 1626 1646 1625 1646 0.98

15 17 0.0091 0.68 10.4 0.1 1 23 1681 1703 1681 1703 0.97

16 17 6.4e-05 0.0048 17.2 0.6 2 23 1795 1817 1794 1817 0.93

17 17 0.0046 0.34 11.3 0.5 3 23 1873 1893 1873 1893 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.29	21	5.7	1.0	3	23	572	593	571	593	0.93
2	17	0.18	14	6.3	2.7	3	22	701	720	699	720	0.89
3	17	0.00062	0.046	14.1	3.3	1	22	824	845	824	847	0.90
4	17	0.071	5.3	7.6	0.1	2	21	859	878	858	879	0.93
5	17	0.00072	0.054	13.8	0.2	2	23	1015	1037	1014	1037	0.95
6	17	0.0021	0.15	12.4	0.1	1	23	1045	1068	1045	1068	0.96
7	17	0.00027	0.02	15.2	0.2	2	23	1154	1175	1153	1175	0.97
8	17	0.0003	0.022	15.1	2.9	2	23	1280	1302	1279	1302	0.97
9	17	0.023	1.7	9.1	0.2	2	23	1311	1333	1310	1333	0.95
10	17	0.0046	0.34	11.3	0.2	1	23	1346	1369	1346	1369	0.97
11	17	0.00013	0.0096	16.2	1.1	1	23	1450	1472	1450	1472	0.99
12	17	0.002	0.15	12.4	0.9	1	23	1480	1503	1480	1503	0.96
13	17	0.36	27	5.4	0.5	2	19	1511	1528	1510	1529	0.92
14	17	3.3e-05	0.0025	18.1	1.4	3	23	1626	1646	1625	1646	0.98
15	17	0.0091	0.68	10.4	0.1	1	23	1681	1703	1681	1703	0.97
16	17	6.4e-05	0.0048	17.2	0.6	2	23	1795	1817	1794	1817	0.93
17	17	0.0046	0.34	11.3	0.5	3	23	1873	1893	1873	1893	0.98

Sequence Information

Coding Sequence: ATGTGCGACACGGCGGCAACAACAGCTACACCAGTGGCAACTACAACTGTGGGAGCGTCGTCAGTGTCTGGCACTGGAACCAGCCTGGGAACGGCAGCGGCTACAGCAACGACAGCAGGAGCCACACCGCCAGCTACAACCGCAGCGAAACCCGAGCAACAGCGGGCGCGACAAAACTGCTGTCGCCTCTGCATTGCCCCGGCCACGGAATGCATTTCGATCATCAATAGCTATGCGGCTGACAAGGAGCCGCTATCCACAAAAATCCACAACTGTGTGAACATCAAGATAACACCGCAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTAAACTCGTGGCAGAGCTTCAAGAATCGGTCGGTTAGCGCACAGAGCAAACAGCGCCAGTGGCTGGAGGCCAACAAGAGTAAGCTCCTCAGCTATTTGGATTTGAACAGTGCCGAGAATGGAGGAGGtcatcagcagcatcaccaccagtcacagcagcagcatcattcGGAGAATGAGATCGATTTGGAGAAGCCATCGGCCGCCCAAATATTGGACGGCATACCCTCGCTGAAGAAACGCAAATCCCTAACAGTCTATGTGAGTCCTAaaccgcaacaacaacaacaacagcatcagcagcaaccGGCCAGAttgacggcgacggcgacagcaACCTCGTCGCAACAGCAAACCCTGCAGACCCTTCTATTGCAGGTGCCAACGATAACGGtcagctcctcctccaccacaCCAGCACCTGGTGGtggatcagcagcagcaacagcaacagccacagcagcggcaacaacagcggCCGCAGTAtctcagcagcaacagcgccAGCATCAGTATCGTAAatatcagcaacagcagcaacagcagcagcagcagcggggcAAACAGATGATGCAccaacatcagcagcaacatcatcaacagatgcagcatcatcagcatcagcagaagAGACGCCAGCGACAGGCGGGGCGACGTCCTGCTCCTCAACCTACTGGTCTGCCTGGACAGCGAAAATTTAAGCCAAGAGTGTATTTACCCTTGGATATAGCAGTGCCACCATTGCCGCCTCTTCCAGCaccaataacaacaacaacaagcactgctgctgctgctgctgctccagcacCAGGAGCAGTGCAAATTCTGGCTCCCGCTGCTGCTAACCATCCGGTTCTTCATGCTGCTGAAATACTGCCACCGGCTGCTGCCACTGTGGTGGGGGGGAATCTGCCGTTGTCGCTGCCACTTGATTTCAGCCAAAGTACCAGCAAGAACGTCTTACCGTCCACGTCCACATCCACGTACAGCCATAGCACCACCATAGCTCAAGCCaccgctgcggcggcggcggcatctGCATCTGCTACCGGCATCTcgtccgtctccgtctccatgCACCAACATGCGACAGCACCGCTGCTAATGCCGCCACTGCCCGCAATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAATCCGATGACATGGTCGATCCCACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATGTACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTGAACGCAGAGACAGCGGCCGCCTCGCTGCCGCCAAATGCTGTGGCTAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGCCTCCAGTTTTCGACACGTGCCAATGCCCGACGCCATGAGCGAAATTTGCACCCAAATCTGTTCCAACTGTCGACGGACTCGCCCAACAATACGCCCATCACAAAGCCCACCCCGGCACTGGCGGCTGCATTGGAGATTCAGCGAGCCGCCGCCGAGGCGGCCACCGAGGAGGCCAGCAAAGCTGCAGGCGCTGCCGGGGGTAATATATCGACCCAAAAATACCGTCAGGTGGTGATGAATGCCTTCATCAAGTGCGAGGGTGGGGGCTTCAACTATGACAGTCCCGAGCAGTACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTGGAGCAGTACCAGACGATGACATGTCGCTGCTGCGACAAATACTTCAGTACGTACAAGAACTTTATGGCGCATGTGCGTAAAAAGTATCCGCTGTTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCTCTATTCATTTCACATCTCAAGAAGCGCAACTGCATCAATCTGTTTCGTGTGCTTAACGCCCTGCGCGGCAAGCAGCCAAATTTCCACCCCTCATCGGACATTGGATCGTCGTTTGGTGGAGagaccaccaccaccaccacaaccaTCACCAGTCCCAATGTCGTTgtaccgctgctgctggataACAGCTCGAGCGGCGAACGGCCGGAGAAGCTGCGCGCCAAGGAACTGCTGGTGAATAAGCTTTACGAGTGCAAACTCTGCCCGAAGGGCTTCCGCACCAAGCACGAGTTTCGCACCCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGATTCAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCCGTCGACAGGCGCCGCCACTACAACAACATGGACTGCATTGTTCGCCTACGCTGCATGACGTGTGATGCCAAGGTGGAGACGCATCAGCGTTTCCTCGATCATGTCTATCAGGATCATCTGGGAGGCATAAGCAGCGACAATGCCTCCACTGTGAGTGGAatgggcggcggcggcggcggtggcaggagcagcagcagtattGAGAACTCGCCCGGGAAGCGGAGTCTACTAGGGGCTCTCGGGATCGGGGTAGGCTCCCCCGCCGATGAGTCACGCACCGGCAGTGCAGCGGCGACAGCGGCAGCTGTAGCACCCAATCAAACCTCCACGCCAAAGCCAACATCGGGAGGTGGGGCGGGCACAACACCTGGCTCCCTGAATCGTGATGCTGGTGGTGCACCGAAATCGCAGTATTTTTCACGAATGCCACAGGTATGCCCCATCTGTGGCCAACAgtacaacaactacaacaacgtGTTGCGTCACATGGAATCGAAGCATCCAAACAAACTCCCGGAGACATACAAATGTGTGCGTTGCGGCCTGGGCTATCCGAGAATCTCGTATCTGCGAGAGCATATGATCAACGTGCATGGCGTGGACAAGAATCGCAATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTGAAGCTGGCCGATGGCAGTACACCGAATGTATCCACGGGTCGTTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGACCGGCAGCATGGCAAAGAAGATACGCCTGGACGatagcagcaacaacagcagtctGGTGGGTGGGGTGGCCAGCCAGCAAAAGGAATGCCCCATCTGCAATGCACTGTTCAGCAACAATATCGGCCTGTCTAATCACATGCGCTCGCATTACACGGCCTCGAGTACCGTGAACGCTGCTCTGGTGGCGGCCAATCGCATGACACCCAAATCCCTGACCATAACCGCCGCCCCAGCCATAGAGACGGTCACATCATCGGCCTCAGTGGATGTTGACGATGACGAGGGCAATATGCCGCTCGAATCAGGAAATATTATGGCCAGCCTCAGTGGTGGCAGAggtgttgcttctgctgctactATTGCTGCTGTGCCTCCTGCCATGGTTAATCAGACGCCTCAAGAGCAGGCCGTCTTTCGTCGTAGCCTGGATCAGGCGGCGGATCGTCGCTTCCGTCGGATGCGTTGCCGCATCTGTCAACGGCGTTTTAGCTCAAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTTATCAAATGCAAGCTGTGCAATGCAGAGTTTGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAGGATGAGATGATTGTGAAGCAGTTTGAGTGCGATGTCTGTTCGATTGTCTACAGCTCGGAGCTGGAACTGAAGCAACACAAGAAGAGTGTCCATAAGCTAACATCCGTGTCGGTGTCTGCATCCGCCTCGGCatcggcttcggcttctgcCTCAGCATCCACATCTTCGAAAATCGATGATGATTCACTGATGATAGAGGAGATCGGTGGCAATAGGAGCCGTCACCATCATCAGCACCACAGCAAGGCATCTGGCGATCTGGCCGATCAGTCCATCATCTCCGCTATggctgccaccgccactgccagtgccacaaCTACGCCGCTGTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACAAACAAGAAGCTGGCCATCCACATCAACTCGCACGATGAGTTCGACTCGAACGATTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTATGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCGGACCCAATCGAGTGCACGCTGTGCCGCAAGGTGTTCTTTGACCATCAGATGCTGGACAATCATACGCCGACCTGCAACCGTAAGCCAATTACCGCCACGGGGGCGCATCAGCAAGAGCTGCAGACGCAGACAAATCAGACGCAGGGTCGGGCCGTATTTAGACACAAGACTggcgacgatgacgacgaggaagagcaacagcagcaccaccatcaccatcaccagcagcagcgtaACCATCAGGATGATGCTGGTGATGGaggagcagtagcagcagcagtggcagctgctgccacatCGAGTGGCACCATCAGTGGTGGCAGTACCAAAAAGATGCGCATACCGGAGGTGGCCTGTACAATTTGTGGTGCCCGATTCACCGATCAGGAGCACTTTAGCAAGCACATACAGAAGCATGAACAGGATCTATATGTGGATAATCCGCTGGCAGCGATGTTCGACGATGGGCCGCCGGATGCGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAATGGGGAATATGCGTGCGATATGTGCACGAAGACATTCCCCCTGGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGAatatcaacaacaacaacaattcgGTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCCCAACCAacaacagaagcaacagcagcagaaccaaCAGCAGAACTCCACGTCCACGccgaacaacaacagcagcagcaacaacaacaacagcaacagcaacaacaacagcagcagcagcaagagcaaaTCAATGAAGCGTAAACGTGAATTGAAATGCGAATACTGCCCCTCGACATtcatcagcaacaacaacctgCGACGACACATGTACGAACTGCATAAGCACGAGGTGAGTAGCCTGCCAGCACCGCCCGTGATTGTGGTAGATGACCCACTCTGCTGTCGACGTTGTGGCAATATCAAATTCGAGACGAAAGAACTGTGGATCGAGCATAAGCTAGCCGATGCGAAGGTGGTGCGACCATTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTCATTGTGCCAGTGGCCACACAAGGGGCCATCGACAGAGAACGAGCATCgacagcatcatcatcatcatcagcatcagcatcggcatccGAGGCAACAACATCCAAAGCAAAGGCGTCATCCGTACTGGCGGAGCAACCCGGTGCAGCACTGCAGAAGAAAACGGAGGAAAATGGTGGACTGGATGCAGCGGAGGCGGCGGTAAAGGCAGATGAAGATGATAGCGATATGGAGGATGCCGATAGTTCAGACGCTGATGAAGAAAGCTCTGGCACAGGGGatgaggacgacgacgacgatggcgacgacgacgacgatgacgatgatgatgaagaagaTGATGAAGGTGAGGGCGAAGACGAGGAGGGTGTGCCCCCACCAACACCTGCCACACAActgttgcaacagcagcagcaacacaaacacaaagccAATATTGACAAGGATGAAGATCTCGTCGAAGAAGTGATCAGCTCTGATGATGAGGAGCCTGAGGATGGAGGGGAAGTCGAGAGCGAAAGTCAAACCCAAAGCGAAGAGGACGATGACGAAGATGACGATGAAGACGATgacgacgaggaagaggaacAGGGCACGCAGCCCCTGATGAATGGCAAGTCGAAAGAGCATCAACAGCAAATCGAGGAGATATTGCCCAGctccgacgacgacgaagaggaGGATGGCAATTTAGATGGCCATCTGATGGCCATTGATGATATTATTGAAGAAGAATATGATGAAGACGATGATGTGGAGGAGGTGGACGATGGTGCAGTCCATCCAGATCCCGATGATGTTATCGAAGAGGTCGACGACGATGATGCGGATGAGGTGGATGAAGAGCACACTGTCGATGGGGGGGCCACATCCTCGGCCTCATCGTCAGAGAGCGAATCAACATCCACGACCACATCCAATTCGCATTCAACTGGTGAGCGGCGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCTCTGCATCACAAGCAACAAGcaatgcaacagcaacggcaacggcaacggcaacgacgacgacgacgactgtgTCGAGCAATTGTAA
Protein Sequence: MCDTAATTATPVATTTVGASSVSGTGTSLGTAAATATTAGATPPATTAAKPEQQRARQNCCRLCIAPATECISIINSYAADKEPLSTKIHNCVNIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNSAENGGGHQQHHHQSQQQHHSENEIDLEKPSAAQILDGIPSLKKRKSLTVYVSPKPQQQQQQHQQQPARLTATATATSSQQQTLQTLLLQVPTITVSSSSTTPAPGGGSAAATATATAAATTAAAVSQQQQRQHQYRKYQQQQQQQQQQRGKQMMHQHQQQHHQQMQHHQHQQKRRQRQAGRRPAPQPTGLPGQRKFKPRVYLPLDIAVPPLPPLPAPITTTTSTAAAAAAPAPGAVQILAPAAANHPVLHAAEILPPAAATVVGGNLPLSLPLDFSQSTSKNVLPSTSTSTYSHSTTIAQATAAAAAASASATGISSVSVSMHQHATAPLLMPPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDVPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDSPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPSSDIGSSFGGETTTTTTTITSPNVVVPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTVSGMGGGGGGGRSSSSIENSPGKRSLLGALGIGVGSPADESRTGSAAATAAAVAPNQTSTPKPTSGGGAGTTPGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRNSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDEEETGSMAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITAAPAIETVTSSASVDVDDDEGNMPLESGNIMASLSGGRGVASAATIAAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKKSVHKLTSVSVSASASASASASASASTSSKIDDDSLMIEEIGGNRSRHHHQHHSKASGDLADQSIISAMAATATASATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECTLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTQTNQTQGRAVFRHKTGDDDDEEEQQQHHHHHHQQQRNHQDDAGDGGAVAAAVAAAATSSGTISGGSTKKMRIPEVACTICGARFTDQEHFSKHIQKHEQDLYVDNPLAAMFDDGPPDAAQFKVEGQNENGEYACDMCTKTFPLVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNSVNNSTSMLRELHAVGLTPNQQQKQQQQNQQQNSTSTPNNNSSSNNNNSNSNNNSSSSKSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLCCRRCGNIKFETKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVATQGAIDRERASTASSSSSASASASEATTSKAKASSVLAEQPGAALQKKTEENGGLDAAEAAVKADEDDSDMEDADSSDADEESSGTGDEDDDDDGDDDDDDDDDEEDDEGEGEDEEGVPPPTPATQLLQQQQQHKHKANIDKDEDLVEEVISSDDEEPEDGGEVESESQTQSEEDDDEDDDEDDDDEEEEQGTQPLMNGKSKEHQQQIEEILPSSDDDEEEDGNLDGHLMAIDDIIEEEYDEDDDVEEVDDGAVHPDPDDVIEEVDDDDADEVDEEHTVDGGATSSASSSESESTSTTTSNSHSTGERRASPVSHQKPFPQWSKNLCITSNKQCNSNGNGNGNDDDDDCVEQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580914; iTF_00580919; iTF_00580920; iTF_00471788; iTF_00473969; iTF_00603505; iTF_00517874;
90% Identity: iTF_00580914; iTF_00580920;
80% Identity: -