Basic Information

Insect: Drosophila affinis
Gene Symbol: hang
Assembly: GCA_037356375.1
Location: CM074802.1:15362433-15372452[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.34 28 5.7 1.0 3 23 508 529 507 529 0.93

2 17 0.22 18 6.3 2.7 3 22 637 656 635 656 0.89

3 17 0.00073 0.061 14.1 3.3 1 22 760 781 760 783 0.90

4 17 0.085 7 7.6 0.1 2 21 795 814 794 815 0.93

5 17 0.00085 0.071 13.9 0.2 2 23 949 971 948 971 0.95

6 17 0.0024 0.2 12.5 0.1 1 23 979 1002 979 1002 0.96

7 17 0.00031 0.026 15.3 0.2 2 23 1088 1109 1087 1109 0.97

8 17 0.00035 0.029 15.1 2.9 2 23 1219 1241 1218 1241 0.97

9 17 0.028 2.3 9.2 0.2 2 23 1250 1272 1249 1272 0.95

10 17 0.0054 0.45 11.4 0.2 1 23 1285 1308 1285 1308 0.97

11 17 0.00015 0.013 16.3 1.1 1 23 1385 1407 1385 1407 0.99

12 17 0.0024 0.2 12.5 0.9 1 23 1415 1438 1415 1438 0.96

13 17 0.42 35 5.4 0.5 2 19 1446 1463 1445 1464 0.92

14 17 2.9e-05 0.0024 18.5 1.8 3 23 1548 1568 1547 1568 0.98

15 17 0.00085 0.07 13.9 0.2 1 23 1603 1625 1603 1625 0.97

16 17 7.6e-05 0.0063 17.2 0.6 2 23 1712 1734 1711 1734 0.93

17 17 0.0055 0.45 11.4 0.5 3 23 1790 1810 1790 1810 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.34	28	5.7	1.0	3	23	508	529	507	529	0.93
2	17	0.22	18	6.3	2.7	3	22	637	656	635	656	0.89
3	17	0.00073	0.061	14.1	3.3	1	22	760	781	760	783	0.90
4	17	0.085	7	7.6	0.1	2	21	795	814	794	815	0.93
5	17	0.00085	0.071	13.9	0.2	2	23	949	971	948	971	0.95
6	17	0.0024	0.2	12.5	0.1	1	23	979	1002	979	1002	0.96
7	17	0.00031	0.026	15.3	0.2	2	23	1088	1109	1087	1109	0.97
8	17	0.00035	0.029	15.1	2.9	2	23	1219	1241	1218	1241	0.97
9	17	0.028	2.3	9.2	0.2	2	23	1250	1272	1249	1272	0.95
10	17	0.0054	0.45	11.4	0.2	1	23	1285	1308	1285	1308	0.97
11	17	0.00015	0.013	16.3	1.1	1	23	1385	1407	1385	1407	0.99
12	17	0.0024	0.2	12.5	0.9	1	23	1415	1438	1415	1438	0.96
13	17	0.42	35	5.4	0.5	2	19	1446	1463	1445	1464	0.92
14	17	2.9e-05	0.0024	18.5	1.8	3	23	1548	1568	1547	1568	0.98
15	17	0.00085	0.07	13.9	0.2	1	23	1603	1625	1603	1625	0.97
16	17	7.6e-05	0.0063	17.2	0.6	2	23	1712	1734	1711	1734	0.93
17	17	0.0055	0.45	11.4	0.5	3	23	1790	1810	1790	1810	0.98

Sequence Information

Coding Sequence: ATGCTTCGGTCTCGCATCTGTTCCAACTTCTTCAAGCCTCAGCCGCCACAGCTCCAAActccaggcagcagcagtgccctCATAACACCGCAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTTAACTCGTGGCAGAGCTTCAAGAATCGCTCGGTTAGCGCACAAAGCAAACAGCGCCAGTGGCTGGAGGCCAACAAGAGTAAGCTACTCAGCTATTTGGATTTGAACTCTGCCGCCGagaatggaggaggaggaggtcacCACCAGAACCAGtcacaccagcagcagcagccgcagcaccATCATTTGGAGAATGAGATTGATTTGGAGAAGCCATCGGCCGCCCAAATATTGGACGGCATACCGTCGCTGAAGAAACGCAAATCTTTAACAGTCTATGTGAGTCCTAAaccgcaacaacagcaacaacagctgcagcagcagcaacagcagtcgcaGCAACCGGCCAGATTGACGgcaacggcgacggcgacaacAACCTCGTCACAGCAGCAAACCCTGCAGACCCTTCTATTGCAGGTGCCAACGATAACGGtcagctcctcctccactaCACCAGCATCTGGTGGtggatcagcagcagcagcaacagcagcggcagcagtatctcagcagcagcagcgccagcatcAGTATCGTAAatatcagcaacagcagcggggCAAACAGATGAtgcaccaacagcaacagcagcagcaacagcaacatcatcaacagctgcaacatcatcagcatcagcagaagAGACGCCAGCGGCAGACGGGGCGACGCCTTGCTCCTCAACCTTCTGGTCTGCCTGGACAGCGAAAATTTAAGCCAAGAGTGTATTTGCCCTTGGATATAGCAGTGCCACCATTGCCGCCTCTTCCAGCAGCAACGACCACTGCTATTGTCACTGCGGCTCCAGCACCTGGACCAAGTCCAGTAACAATTCTGgctcccgctgctgctctggctTCCCATCCGGTTCCTCATGCTGCTGAAATACTGCCACCGGCTGCTGCCACTGTGGTGGGGGGGAATCTGCCGTTGTCGTTGCCACTTGATTTCAGCCAAAGTAGCAGCAAGAACGTCTTACCGTCCACATCCACGTACAGCCATAACAGCACCATAGCTCACGCCAccgctgcagcggcggcggcggcatctgcatctgccacCGGCATGCCACCGtcggtctccgtctccatgCACCAACATGCGACAGCACCGCTTCTAATGCCGCCACTGCCCGCTATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAATCCGACGACATGGTCGATCCCACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATATACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTAAACGCAGAGACAGCGGCCGCCTCTCTGCCGCCAAATGCCGTGGCAAATGTGGCCGCCGCCGGGGACTCAAAGGTGGCCAGCTGCAGGGCATGCAGCCTTCAGTTTTCGACACGTGCCAATGCCCGTCGCCATGAGCGAAATTTGCACCCAAATCTGTTCCAACTGTCGACGGACTCGCCCAACAATACGCCAATCACAAAGCCCACACCGGCACTGGCGGCAGCATTGGAGATTCAGCGTGCCGCCGCCGAGGCGGCCACCGAGGAGGCCAGCAAAGCTGCGGGCGCTGCCGGGGGTAATATATCGACCCAAAAGTATCGTCAAGTGGTGATGAATGCCTTCATCAAGTGCGAGGGTGGGGGCTTCAACTATGAAAATCCCGAGCAATACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATTGAGCAGAATTACGAATTCCTGGAGCAGTACCAGACGATGACATGCCGCTGCTGTGACAAATACTTCAGTACGTACAAGAATTTTATGGCGCATGTGCGTAAAAAGTATCCGCTGTTGCCGCGCAATCTCTGCTTCAACTGCCTAAAGATGAACGAATCGAAGGCTCTGTTCATTTCGCATCTCAAGAAGCGCAACTGCATCAATCTGTTTCGTGTGCTGAACGCCCTTCGCGGCAAGCAGCCAAATTTCCATCCCTCATCGGACATTGGATCATCATCGTTTGGTGGAGAGACCACCAttaccaccaccatcaccagtCCCAATGTCGTTGTACCGCTACTGTTGGATAACAGCTCAAGCGGCGAACGGCCAGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTTTACGAGTGTAAACTCTGCCCAAAGGGCTTCCGCACCAAGCACGAGTTTCGCACCCATGTGTACGACAAGCATGCGGACGTGCAGCGCAAGGACAACAATTCGATTCAGTGCAGCTTCTGTGGTCTGGACTTTGCCGATCCAGTGGACAGGCGCCGCCACTACAACAATATGGACTGCATTGTTCGCCTCCGGTGCATGACATGTGATGCCAAGGTGGAGACACATCAGCGTTTCCTCGATCATGTCTATCAGGATCATCTTGGGGGCATAAGCAGCGAGAATGCCTCCACTGTGAGTGGAATGGGCGGCACCGGCGGtggcaggagcaacagcagtatTGAGAACTCGCCTGGGAAGCGGAGTCTACTAGGTGCTCTCGGGATTGGGGTTGGCTCCCCCGCCGATGAGTCACGAAGTGGCGGCAGTGCAGCGGCAACTGCAGCACCAAATCAAACCTCTACGCCAAAACCAACATCGGGTGGTGGGGCGGCGGGCACGACATCTGGCTCTCTAAATCGTGATGCTGGTGGTGCGCCGAAATCGCAGTATTTCTCACGAATGCCACAGGTTTGCCCCATCTGTGGCCAACAGTACAACAACTACAATAACGTGCTGCGTCACATGGAATCGAAGCATCCGAACAAACTCCCGGAGACATACAAATGTGTTCGTTGCGGCCTGGGCTATCCGAGGATCTCGTATCTCCGAGAGCATATGATCAACGTTCATGGCGTGGACAAGAATCGTCATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTGAAGCTGGCCGACGGCAGTACACCGAATGTATCCACGGGTCGTTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGACCGGCAGCGTGGCCAAGAAGATACGTCTGGACgatagcagcaacaacagcagtctGGTGGGCGGCGTGGCCGGCCAGCAAAAGGAATGCCCCATCTGTAACGCACTGTTCAGCAACAATATCGGCTTGTCAAATCACATGCGCTCGCATTACACGGCCTCGAGTACCGTGAATGCTGCTCTGGTGGCGGCCAATCGTATGACACCCAAATCCTTGACCATAACCGCCACCCCAGCCACAGAGACGGTCACATCATCGACCTCGGTGGATGTAGACGATGATGAGGGCATTATAACGCTCGAAACGGGAAATATTATGGCCAGCATCAGTGGTGGTAGAGGTGTCgcttctgctgcagctgctgctggtactgGTGCTGTTGCCGTCCCCCCTGCCATGGTTAATCAGACCCCCCAAGAGCAGGCAGTCTTTCGCCGTAGCCTGGATCAGGCAGCGGATCGTCGGTTCCGCCGGATGCGTTGCCGCATCTGTCAGCGGCGTTTTAGCTCTAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTTATCAAATGTAAGCTGTGCAATGCAGAGTTTGCCTACGAGAAGGGTCTGAAGGTGCATTTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTGTGAAGCAGTTTGAGTGCGATGTCTGCTCAATTGTGTACAGCTCAGAACTGGAACTGAAGCAGCACAAGAAGAGTGTCCACAAACTGGCATCCGTGTCGGTGTCTGCATCCGCCTCGGCATCGgcttctgcctctgcatcCACATCCTCGAAAATCGATGATGATTCACTGATGATAGAGGATATCGGTGGCAATAGAAGCAGTcaccatcatcagcatcacAGCAAGGCATCTGGTGATCTGGCCGATCAGTCCAACATCTCTGCTgtcaccgccaccgccactgccacaacgACGCCGTTGTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACAAACAAGAAGCTGGCCATCCACATCAACTCGCACGATGAGTTCGACTCGAATGATTATTCGTGCAAGGACTGCGGAAATGTCTATAGCGGCCGCAAGAGTCTATGGGTGCATCGCTACAAAAAGCATCCGCAGGTGCCCGACCCAATCGAGTGCACGCTGTGCCGCAAGGTATTCTTTGACCATCAGATGCTGGACAACCACACGCCAACCTGCAACCGAAAGCCGATTACCGCCACGGGGGCGCAtcagcaggagctgcagaCAAATCCGGCGCTGGGTCGGCCCGTATTCAGGCACAAGACTggcgacgatgatgacgaagaagagcagcagcagcagcagcttaaTCCACAGGAGGATGCTGGCGATGGAGGAGCAGTAGCGGTAGCCACATCGAGTGGTGGCACCATTAGTGCGGGCAGTACCAAAAAGTTGCGCTTACTGGATGTGGCCTGTACAATTTGCGGTGCCCGATTCACCGATCAGGAGCACTTTACCAAGCACTTACAGAAGCATGAACAGGATCTGTATGTGGATAATCCGCTGGCAGCGATGTTCGACGATGGGCCAGCGGATGTGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAATGGGGAATATGCGTGCGATATGTGTACGAAGACATTCCCCCAAGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGAatatcaacaacaacaacaattcgGTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGATGCCCAACcaacaacagaagcaacagcagagccAACAGCAGAGCAATTCCACGTCTACGccgagcaacaacaacagcagcagcaacaacaacaacagcagcagcagcaagagcaaaTCAATGAAGCGTAAACGTGAATTAAAATGCGAATACTGCCCCTCGACATTCattagcaacaacaacctgcGACGACACATGTATGAACTGCATAAGCACGAGGTGAGTAGCCTGCCAGCACCACCCGTGATTGTGGTAGATGACCCGCTAAGCTGCCGACGTTGTGGCGATATCAAATTCGCGACGAAAGAACTGTGGATCGAGCACAAGCTGGCTGATGCGAAGGTGGTGCGACCATTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTTATTGTGCCAGTGTCCACACAAACGGCCATCGACAGAGAAAAACGAGCATCGAcagaatcatcatcatcagcctcCGAGGCAACAACATCCAAAACGAAGGCGTCATCCGCCTTGGCGGCTTCAACCAGCGCAGCATTGCAGAAAAAAACGGAGGAAAATGGTGGACTGGAGACAGCAGAGGCGGCGGTAAAGGCAGAGGAAGATGATAGCGAAATGGAGGATGGCGACAGTTCAGACGCTGATGAAGAAAGCTCTGGCACAGGGGATGACGACGATGaagacggcgacgacgacgacgatgatgatgacgatgaagaCGATGACGAAGATGAGGGCGAAGACGAGGAGGGTGTGCCCCCACCAACACCTGCCACACAActgttgcaacagcaacacaaatCCAATATTGACAAGGATGAAGATCTCGTCGAAGAAGTGATGAGCTCTGATGAGGAGGCGGAGGAAGGCGAAAGCCAAAGCGATGAGGACGATGACGAAGATGACGATgaagacgacgatgacgaggaggaagaggaacagggacagggacaggaacAGGGTTCACAGCCCCTGATGAATGGCAAGTCGAAAGAGCATCAACAGCAAATCGAAGAGATATTGCCCAGctccgacgacgacgaagaggAGCAGGATGGCAATTTAGATGGCCATTTGATGGCCATTGAAGACATTATTGAAGAAGAATATGATGAAGACGATGATGTGGAGGAGGTAGACGATGGTGCAGTCCATCCAGATCCCGACGATGTTATCGAAGAGGTCGACGACGATGATGCGGATGAAGTGGATGATGAGCAGAATGTCGATGGGGGGGCCACATCGTCGGCCTCATCGTCAGAGAGCGAATCAACATCCACGACCACATCCAATTCGCATTCAACTGGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCTCTACCTCACAAGCAGCAAGCAACGCAACAGCAacggcgacagcgacggcGATGACTGTGTCCAGCAATTGTAA
Protein Sequence: MLRSRICSNFFKPQPPQLQTPGSSSALITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNSAAENGGGGGHHQNQSHQQQQPQHHHLENEIDLEKPSAAQILDGIPSLKKRKSLTVYVSPKPQQQQQQLQQQQQQSQQPARLTATATATTTSSQQQTLQTLLLQVPTITVSSSSTTPASGGGSAAAATAAAAVSQQQQRQHQYRKYQQQQRGKQMMHQQQQQQQQQHHQQLQHHQHQQKRRQRQTGRRLAPQPSGLPGQRKFKPRVYLPLDIAVPPLPPLPAATTTAIVTAAPAPGPSPVTILAPAAALASHPVPHAAEILPPAAATVVGGNLPLSLPLDFSQSSSKNVLPSTSTYSHNSTIAHATAAAAAAASASATGMPPSVSVSMHQHATAPLLMPPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDIPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYENPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPSSDIGSSSFGGETTITTTITSPNVVVPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSENASTVSGMGGTGGGRSNSSIENSPGKRSLLGALGIGVGSPADESRSGGSAAATAAPNQTSTPKPTSGGGAAGTTSGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDEEETGSVAKKIRLDDSSNNSSLVGGVAGQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITATPATETVTSSTSVDVDDDEGIITLETGNIMASISGGRGVASAAAAAGTGAVAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKKSVHKLASVSVSASASASASASASTSSKIDDDSLMIEDIGGNRSSHHHQHHSKASGDLADQSNISAVTATATATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECTLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTNPALGRPVFRHKTGDDDDEEEQQQQQLNPQEDAGDGGAVAVATSSGGTISAGSTKKLRLLDVACTICGARFTDQEHFTKHLQKHEQDLYVDNPLAAMFDDGPADVAQFKVEGQNENGEYACDMCTKTFPQVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNSVNNSTSMLRELHAVGLMPNQQQKQQQSQQQSNSTSTPSNNNSSSNNNNSSSSKSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLSCRRCGDIKFATKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVSTQTAIDREKRASTESSSSASEATTSKTKASSALAASTSAALQKKTEENGGLETAEAAVKAEEDDSEMEDGDSSDADEESSGTGDDDDEDGDDDDDDDDDEDDDEDEGEDEEGVPPPTPATQLLQQQHKSNIDKDEDLVEEVMSSDEEAEEGESQSDEDDDEDDDEDDDDEEEEEQGQGQEQGSQPLMNGKSKEHQQQIEEILPSSDDDEEEQDGNLDGHLMAIEDIIEEEYDEDDDVEEVDDGAVHPDPDDVIEEVDDDDADEVDDEQNVDGGATSSASSSESESTSTTTSNSHSTGASPVSHQKPFPQWSKNLYLTSSKQRNSNGDSDGDDCVQQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536223;
90% Identity: iTF_00517874;
80% Identity: -