Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: hang
Assembly: GCA_009870125.2
Location: CM020872.1:15141748-15155483[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.35 27 5.7 1.0 3 23 570 591 569 591 0.93

2 17 0.22 17 6.3 2.7 3 22 699 718 697 718 0.89

3 17 0.00076 0.057 14.0 3.3 1 22 822 843 822 845 0.90

4 17 0.087 6.6 7.6 0.1 2 21 857 876 856 877 0.93

5 17 0.00088 0.066 13.8 0.2 2 23 1014 1036 1013 1036 0.95

6 17 0.0025 0.19 12.4 0.1 1 23 1044 1067 1044 1067 0.96

7 17 0.00032 0.025 15.2 0.2 2 23 1153 1174 1152 1174 0.97

8 17 0.00036 0.027 15.1 2.9 2 23 1279 1301 1278 1301 0.97

9 17 0.028 2.2 9.1 0.2 2 23 1310 1332 1309 1332 0.95

10 17 0.0077 0.59 10.9 0.2 1 23 1345 1368 1345 1368 0.97

11 17 0.00016 0.012 16.2 1.1 1 23 1449 1471 1449 1471 0.99

12 17 0.0025 0.19 12.4 0.9 1 23 1479 1502 1479 1502 0.96

13 17 1.8 1.4e+02 3.4 0.4 2 19 1510 1527 1509 1528 0.92

14 17 4.1e-05 0.0031 18.1 1.4 3 23 1625 1645 1624 1645 0.98

15 17 0.011 0.84 10.4 0.1 1 23 1680 1702 1680 1702 0.97

16 17 7.8e-05 0.0059 17.2 0.6 2 23 1786 1808 1785 1808 0.93

17 17 0.0056 0.43 11.3 0.5 3 23 1864 1884 1864 1884 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.35	27	5.7	1.0	3	23	570	591	569	591	0.93
2	17	0.22	17	6.3	2.7	3	22	699	718	697	718	0.89
3	17	0.00076	0.057	14.0	3.3	1	22	822	843	822	845	0.90
4	17	0.087	6.6	7.6	0.1	2	21	857	876	856	877	0.93
5	17	0.00088	0.066	13.8	0.2	2	23	1014	1036	1013	1036	0.95
6	17	0.0025	0.19	12.4	0.1	1	23	1044	1067	1044	1067	0.96
7	17	0.00032	0.025	15.2	0.2	2	23	1153	1174	1152	1174	0.97
8	17	0.00036	0.027	15.1	2.9	2	23	1279	1301	1278	1301	0.97
9	17	0.028	2.2	9.1	0.2	2	23	1310	1332	1309	1332	0.95
10	17	0.0077	0.59	10.9	0.2	1	23	1345	1368	1345	1368	0.97
11	17	0.00016	0.012	16.2	1.1	1	23	1449	1471	1449	1471	0.99
12	17	0.0025	0.19	12.4	0.9	1	23	1479	1502	1479	1502	0.96
13	17	1.8	1.4e+02	3.4	0.4	2	19	1510	1527	1509	1528	0.92
14	17	4.1e-05	0.0031	18.1	1.4	3	23	1625	1645	1624	1645	0.98
15	17	0.011	0.84	10.4	0.1	1	23	1680	1702	1680	1702	0.97
16	17	7.8e-05	0.0059	17.2	0.6	2	23	1786	1808	1785	1808	0.93
17	17	0.0056	0.43	11.3	0.5	3	23	1864	1884	1864	1884	0.98

Sequence Information

Coding Sequence: ATGTGCGACAcggcggcaacaacagctacaCCAGTGGTGGCAGCTACAACTGTGGGAGCGGCTTCGGTGTCTGGCACTGGAACCAGCCAGGGAACGGCAGCGGCTACACCAGCGACAGCAGGAGCCACACCGCCAGCTACAACCGCATCGAAACCCGAGCAACAGCGGGCGCGACAAAACTGCTGTCGCCTCTGCATTGCCCCGGCCACGGAATGCATTTCGATCATCAATAGCTATGCGGCCGACAAGGAGCCGCTATCGACAAAAATCCACAACTGTGTGGACATAAAGATAACACCACAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTTAACTCGTGGCAGAGCTTCAAGAATCGGTCGGTTAGCGCACAGAGCAAACAGCGGCAGTGGCTGGAGGCCAACAAGAGTAAGCTCCTCAGCTATTTGGATTTGAACAGTGCCGAGAATGGAGGAGGtcatcagcagcatcaccatcagaaccagcagcagcatcattcGGAGAATGAGATCGATTTGGAGAAGCCATCGGCCGCCCAAATATTGGACGGCATACCCTCGCTGAAGAAACGCAAATCCCTAACAGTCTATGTGAGTCCTaaaccgcaacaacaacaacaacaacagcatcagcagcaaccgGCCAGATTTACGGCGACGGCTACGGCGACAGCAACCTCGTCGCAACAGCAAACCCTGCAGACCCTTCTATTGCAGGTGCCAACGATAACGgtcagctcctcctccaccacacCAGCATCTGGTGgtggatcagcagcagcaacagcagcaacaacaacagcagcggccgcagtatctcagcagcagcagcgccagcatcAGTATCGTAAatatcagcaacagcaacagcagcagcggggcaAACAGATGATgcaccaacatcagcagcaacagcagcaacatcatcaacagatgcagcatcatcagcatctgCTGAAGAGACGCCAGCGACAGGCGGGGCGACGTCCTGCTCCTCAACCTACTGGTCTGCCTGGACAGCGAAAATTTAAGCCAAGAGTGTATTTACCCTTGGATATAGCAGTGCCCCCATTGCCGCCACTtccagcaccaacaacaagcactgctgctgctgctgctgttgcttcagCACCAGGAGCAGTGCAAATTCTGGCTCCCGCTGCTGCAAACCATCCGGTTCTTCATGCTGCTGAAATACTGCCACCGTCTGCTGCCACTGTGATGGGGGGGAATCTGCCGTTGTCGCTGCCACTTGATTTCAGCCAAAGTACCAGCAAGAACGTCTTACCGTCCACATCCACGTACAGCCATAGCACCACCATAGCTCACGCCACCGCTccggctgcggcggcggcatccGCATCTGCTACCGGCATCTcgtccgtctccgtctccatgcACCAACATGCGACAGCACCGCTGCTAATGCCGCCACTGCCCGCAATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAATCCGATGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTGAACGCAGAGACGGCGGCCGCCTCGCTGCCGCCCAATGCTGTGGCTAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGCCTCCAGTTTTCGACACGTGCCAATGCCAGGCGCCATGAGCGAAATTTGCACCCAAATCTGTTCCAATTGTCGACGGACTCGCCCAACAATACGCCCATCACAAAGCCCACCCCGGCACTGGCGGCTGCATTGGAGATTCAGCGTGCCGCCGCCGAAGCGGCCACCGAGGAGGCCAGCAAAGCTGCAGGCGCTGCCGGGGGTAATATATCGACCCAAAAATACCGTCAGGTGGTGATGAACGCCTTCATCAAGTGCGAGGGTGGGGGCTTCAACTATGACAGTCCCGAGCAGTACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTGGAGCAGTACCAGACGATGACATGTCGCTGCTGCGACAAATACTTCAGTACGTACAAGAACTTTATGGCGCATGTGCGTAAAAAGTATCCGCTGTTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCTCTGTTCATTTCCCATCTCAAGAAGCGCAACTGCATCAATCTATTTCGTGTGCTGAACGCCCTGCGCGGCAAGCAGCCAAATTTTCACCCCTCATCGGACATTGGATCGTCGTTCGGTGGAGagaccaccaccaccaccacaaccatCACCAGTCCCAATGTCGTTgtaccgctgctgctggataaCAGCTCGAGCGGCGAACGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTTTACGAGTGCAAACTCTGCCCGAAGGGCTTCCGCACCAAGCACGAGTTTCGCACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAACTCGATTCAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCCGTCGACAGGCGCCGCCACTACAACAACATGGACTGCATTGTTCGCCTACGCTGCATGACGTGCGACGCCAAGGTGGAGACGCATCAGCGTTTTCTCGATCATGTCTATCAAGATCATCTGGGGGGCATAAGCAGCGACAATGCCTCCACTGTGAGTGGAttgggcggcggcggaggcggcggcggcaggagcagcagcagtattGAGAACTCGCCCGGGAAGCGGAGTCTACTAGGGGCTCTCGGGATCGGTGTTGGCTCCCCCGCCGATGAGTCACGCACCGGCAGTGCAGCGGCGACAGCGGCAGCCGTAGCACCCAATCAAACCTCCACGCCAAAGCCGACATCGGGAGGTGGGGCGGGCACAACACCTGGCTCCCTGAATCGTGATGCTGGTGGTGCACCGAAATCGCAGTATTTTTCACGAATGCCCCAGGTATGCCCCATCTGTGGCCAACAgtacaacaactacaacaacgtGCTGCGTCACATGGAATCGAAGCATCCAAACAAACTCCCGGAGACCTACAAATGTGTGCGCTGCGGCCTGGGCTATCCGAGAATCTCGTATCTGCGAGAGCATATGATCAACGTGCATGGCGTGGACAAGAATCGAAATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTGAAGCTGGCCGATGGCAGTACACCGAATGTGTCCACGGGTCGTTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGACCGGCAGCATGGCCAAGAAGATACGCCTGGACgatagcagcaacaacagcagtctGGTGGGTGGGGTGGCCAGCCAGCAAAAGGAATGCCCCATCTGCAATGCACTGTTTAGCAACAATATTGGCCTGTCGAATCACATGCGCTCACATTACACGGCCTCGAGTACCGTGAACGCTGCTCTGGTGGCGGCCAATCGCATGACACCCAAATCCCTGACCATAACCGCCGCCCCAGCCATAGAGACGGTCACATCATCGGCCTCAGTCGATGTTGACGATGACGAGGGCGTTATGCCGCTCGAATCCGGAAATATTATGGCCAGCGTCAGCGGTGGCAGAGGTGTTGCTTCTGTTTCAGCTATTGCTGCTGTGCCTCCTGCCATGGTTAATCAGACGCCTCAAGAGCAGGCCGTCTTTCGTCGCAGCCTGGACCAGGCGGCGGATCGTCGCTTCCGCCGGATGCGTTGCCGCATCTGTCAGCGGCGTTTTAGCTCAAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTTATCAAGTGCAAGCTGTGCAATGCAGAGTTTGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAGGATGAGATGATTGTGAAGCAGTTTGAGTGCGATGTCTGTTCGATTGTCTACAGCTCGGAGCTGGAACTGAAGCAGCACAAGCAGAGCGTCCATAAGCTGACATCCGTGTCGGTGTCTGCATCCGCCTCGGCatcggcttcggcttctgcCTCGGCATCCACATCCTCGAAAATCGATGATGATTCACTGATGATGGAGGACATCGGTGGCAATAGAAGCCGtcaccatcatcagcagcacaGCAAGGCATCTGGCGATCTGGCCGATCAGTCCATCATCTCCGCCAtggctgccaccgccactgccagtgccacaaCGACGCCGCTCTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGATGAGTTCGACTCGAACGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTATGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCGGACCCAATCGAGTGCATGCTGTGCCGCAAGGTGTTCTTTGACCATCAGATGCTGGACAATCATACGCCGACCTGCAACCGTAAGCCAATTACCGCCACGGGGGCGCatcagcaggagctgcagacGCAGTCAAATCAGCCGCAAGGTCGGGCCGTATTTAGGCACAAGACTggcgacgatgacgacgaggaagagcaacagcagcatcaccagcagcagcaacagcgtaACCATCAGGAGGATGCTGGCGATGGaggagcagtagcagcagcagctgctgccgctgccgctgccacatcGAGCGGCACCATCAGCGGTGTCAGTACCAAAAAGATGCGCATACCGGAGGTGGCCTGTACAATTTGTGGCGCCAGATTCACTGATCAGGAGCACTTTAGCAAGCACATACAGAAGCATGAACAGGATCTATATGTGGATAATCCGCTGGCAGCGATGTTCGACGATGGGCCGGCGGATGCGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAACGGGGAATACGCGTGCGATATGTGCACGAAGACATTCCCCCTGGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGaatatcaacaacaacaacaacaacaattcgGTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCCCaaccaacaacagaagcaacagcagcagaactcCACGTCCACgccgaacaacaacagcagcagcaacaacaacaacagcaacagcagcaagagcagaTCAATGAAGCGTAAACGTGAATTGAAATGCGAATACTGCCCCTCGACAttcatcagcaacaacaacctgcGACGCCACATGTACGAACTGCATAAGCACGAGGTGAGTAGCCTGCCAGCACCGCCCGTGATTGTGGTGGATGACCCGCTCTGCTGTCGACGTTGTGGCAATATCAAATTCGAGACGAAAGAACTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTGCGACCATTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTCATTGTGCCAGTGGCCACACAAGGGGCCATCGACAGAGAACGAGCATCgacagcatcatcatcatcatcgtcagcatcggcagcatcgGCTTCGGCATCCGAGGCAACAACATCCAAAGCAAAGGCGTCGTCCGTACTGGCGGAGCAACCCGGTGCCATACTGCAGAAGAAAACGGAGGAAAATGGTGGACTGGATGGAGCAGAGGCGGCGGTAAAGGCAGATGAAGATGATAGCGATATGGAGGATGCCGACAGTTCAGACGGTGATGAAGAAAGCTCTGGCACAggggatgaagacgacgacgacgatgatgacgacgacgacgacgacgacgacgacgatgatgacgacgaagATGAGGGCGAAGACGAGGAGGGTGTGCCCCCACCAACACCTGCCACACAACtgttgccacagcagcaggagcagcagcagcaacacaaacacaaagccAATATTGACAATGATGAAGATCTCGTCGAAGAAGTGATCAGCTCTGATGATGAAGAGCCTGAGGATGGAGGGGAAGTCGAGAGCGAAAGTCAAACAGAAAGCGAAgaggacgatgacgaggatgacgatgaagacgatgacgacgaggaagaggaacagggacaggaacaggaacaggccTCGCAGCCCCTGGTGAATGGCAAGTCGAAAGAGCATCAACAGCAAATCGATGAGATATTGCCCAGctccgacgacgacgaagtgGGGGATGGCAATTTAGATGGCCATCTGATGGCCATTGATGACATTATTGAAGAAGAATTTGATGAAGACGATGATATGGAGGAGGTGGACGATGGTGCAGTCCATCCAGATCCCGATGATGTTATCGAAGAGGTCGACGACGATGATGCGGATGAGGTGGATGAAGAGCACAATGTCGATGGGGGCGGCACATCATCGGCCTCATCGTCAGAGAGTGAATCAACATCCACGACCACATCCAATTCGCATTCAACTGGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCTCTGCCTCACAAGCAACAAgcaatgcaacagcaacagcaacggcaacggcaacgacgacgactgtGTCGAGCAATTGTAA
Protein Sequence: MCDTAATTATPVVAATTVGAASVSGTGTSQGTAAATPATAGATPPATTASKPEQQRARQNCCRLCIAPATECISIINSYAADKEPLSTKIHNCVDIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNSAENGGGHQQHHHQNQQQHHSENEIDLEKPSAAQILDGIPSLKKRKSLTVYVSPKPQQQQQQQHQQQPARFTATATATATSSQQQTLQTLLLQVPTITVSSSSTTPASGGGSAAATAATTTAAAAVSQQQQRQHQYRKYQQQQQQQRGKQMMHQHQQQQQQHHQQMQHHQHLLKRRQRQAGRRPAPQPTGLPGQRKFKPRVYLPLDIAVPPLPPLPAPTTSTAAAAAVASAPGAVQILAPAAANHPVLHAAEILPPSAATVMGGNLPLSLPLDFSQSTSKNVLPSTSTYSHSTTIAHATAPAAAAASASATGISSVSVSMHQHATAPLLMPPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDVPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDSPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPSSDIGSSFGGETTTTTTTITSPNVVVPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTVSGLGGGGGGGGRSSSSIENSPGKRSLLGALGIGVGSPADESRTGSAAATAAAVAPNQTSTPKPTSGGGAGTTPGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRNSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDEEETGSMAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITAAPAIETVTSSASVDVDDDEGVMPLESGNIMASVSGGRGVASVSAIAAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKQSVHKLTSVSVSASASASASASASASTSSKIDDDSLMMEDIGGNRSRHHHQQHSKASGDLADQSIISAMAATATASATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECMLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTQSNQPQGRAVFRHKTGDDDDEEEQQQHHQQQQQRNHQEDAGDGGAVAAAAAAAAAATSSGTISGVSTKKMRIPEVACTICGARFTDQEHFSKHIQKHEQDLYVDNPLAAMFDDGPADAAQFKVEGQNENGEYACDMCTKTFPLVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNNNSVNNSTSMLRELHAVGLTPNQQQKQQQQNSTSTPNNNSSSNNNNSNSSKSRSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLCCRRCGNIKFETKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVATQGAIDRERASTASSSSSSASAASASASEATTSKAKASSVLAEQPGAILQKKTEENGGLDGAEAAVKADEDDSDMEDADSSDGDEESSGTGDEDDDDDDDDDDDDDDDDDDDEDEGEDEEGVPPPTPATQLLPQQQEQQQQHKHKANIDNDEDLVEEVISSDDEEPEDGGEVESESQTESEEDDDEDDDEDDDDEEEEQGQEQEQASQPLVNGKSKEHQQQIDEILPSSDDDEVGDGNLDGHLMAIDDIIEEEFDEDDDMEEVDDGAVHPDPDDVIEEVDDDDADEVDEEHNVDGGGTSSASSSESESTSTTTSNSHSTGASPVSHQKPFPQWSKNLCLTSNKQCNSNSNGNGNDDDCVEQL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536223;
90% Identity: iTF_00536223;
80% Identity: -