Basic Information

Insect: Drosophila helvetica
Gene Symbol: hang
Assembly: GCA_963969585.1
Location: OZ018401.1:5307044-5319311[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.34 33 5.7 1.0 3 23 517 538 516 538 0.93

2 18 0.12 12 7.0 3.0 3 22 646 665 644 665 0.89

3 18 0.00074 0.07 14.0 3.3 1 22 766 787 766 789 0.90

4 18 0.085 8.1 7.6 0.1 2 21 801 820 800 821 0.93

5 18 0.00085 0.081 13.8 0.2 2 23 954 976 953 976 0.95

6 18 0.0025 0.24 12.4 0.1 1 23 984 1007 984 1007 0.96

7 18 0.00032 0.03 15.2 0.2 2 23 1093 1114 1092 1114 0.97

8 18 0.0011 0.11 13.5 4.7 2 23 1224 1246 1223 1247 0.96

9 18 0.028 2.6 9.1 0.2 2 23 1255 1277 1254 1277 0.95

10 18 0.0055 0.52 11.3 0.2 1 23 1290 1313 1290 1313 0.97

11 18 0.00015 0.015 16.2 1.1 1 23 1395 1417 1395 1417 0.99

12 18 0.0024 0.23 12.4 0.9 1 23 1425 1448 1425 1448 0.96

13 18 0.43 41 5.4 0.5 2 19 1456 1473 1455 1474 0.92

14 18 1.5e-05 0.0014 19.4 1.5 3 23 1560 1580 1559 1580 0.98

15 18 0.00085 0.081 13.8 0.2 1 23 1615 1637 1615 1637 0.97

16 18 7.6e-05 0.0072 17.2 0.6 2 23 1726 1748 1725 1748 0.93

17 18 0.0055 0.52 11.3 0.5 3 23 1804 1824 1804 1824 0.98

18 18 0.00013 0.012 16.5 2.1 1 23 2166 2188 2166 2188 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.34	33	5.7	1.0	3	23	517	538	516	538	0.93
2	18	0.12	12	7.0	3.0	3	22	646	665	644	665	0.89
3	18	0.00074	0.07	14.0	3.3	1	22	766	787	766	789	0.90
4	18	0.085	8.1	7.6	0.1	2	21	801	820	800	821	0.93
5	18	0.00085	0.081	13.8	0.2	2	23	954	976	953	976	0.95
6	18	0.0025	0.24	12.4	0.1	1	23	984	1007	984	1007	0.96
7	18	0.00032	0.03	15.2	0.2	2	23	1093	1114	1092	1114	0.97
8	18	0.0011	0.11	13.5	4.7	2	23	1224	1246	1223	1247	0.96
9	18	0.028	2.6	9.1	0.2	2	23	1255	1277	1254	1277	0.95
10	18	0.0055	0.52	11.3	0.2	1	23	1290	1313	1290	1313	0.97
11	18	0.00015	0.015	16.2	1.1	1	23	1395	1417	1395	1417	0.99
12	18	0.0024	0.23	12.4	0.9	1	23	1425	1448	1425	1448	0.96
13	18	0.43	41	5.4	0.5	2	19	1456	1473	1455	1474	0.92
14	18	1.5e-05	0.0014	19.4	1.5	3	23	1560	1580	1559	1580	0.98
15	18	0.00085	0.081	13.8	0.2	1	23	1615	1637	1615	1637	0.97
16	18	7.6e-05	0.0072	17.2	0.6	2	23	1726	1748	1725	1748	0.93
17	18	0.0055	0.52	11.3	0.5	3	23	1804	1824	1804	1824	0.98
18	18	0.00013	0.012	16.5	2.1	1	23	2166	2188	2166	2188	0.98

Sequence Information

Coding Sequence: ATGTGCGGCGCACTGGTCGAGGCCGagcgtcgctgctgctgctgctgctgccgccgccgccgccatATAACGCCGCAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTGAACTCGTGGCAGAGCTTCAAGAATCGCTCGGTTAGCGCACAGAGCAAACAGCGCCAGTGGCTGGAGGCCAACAAGAGTAAGCTGCTCAGCTATTTGGATTTGAACAGTGCCGCCGAGAatggagcaggaggaggaggaggtcaccaccagcagcagcagccgcagcaccaTCATTCGGAGAATGAGATTGATTTGGATAAGCCATCGGCCGCCCAAATATTGGACGGCATACCCTCGCTGAAGAAACGCAAATCTCTAACAGTTTATGTGAGTCCTAaaccgcaacaacaacaacaacaacaacagctgcagcagcagcagcaacagcagccgcagcaaccGGCCAGAttgacggcgacggcgacaacAACCTCGTCACAGCAGCAAACCCTGCAGACCCTTCTATTGCAGGTTCCAACGATAACGGTCAGCGCCTCCTCCACCACACCAGCATCTGGTGGTggatcagcagcagccacagcagcagcagcagcagcagcggcaacagcagcagcggcagccgcagcagtatctcagcagcagcaacgccaGCATCAGTATCGTAAAtatcagcaacagcaacagcagagggGCAAACAGATGatgcaccagcagcaacagcagcaacatcatcaACAGCTgcaacatcatcagcatctGCAGCAGAAGAGACGCCAGCGGCAAACGGGGCGACGTCTTGCTTCTCAACCTTCTGGTCTGCCTGGACAGCGTAAATTTAAGCCAAGAGTGTATTTACCCTTGGATATAGCAGTGCCACCATTGCCGCCTCTTCCAGCACCGACAACCACAACCACTGCTGTtggtactgctgctgctccagctccagcacctgcacctggacctggacctgggccagggccaggaccagTAACGATTGGGGCTCCCGCTGCTGCTCCGGCTTCCCATCCGGTTCTCCATGCTGCTGAAATACTGCCACCGGCTGCTGCCACTGTGGTGGGGGGGAATCTGCCGTTGTCGCTGCCACTTGATTTCAGCCAAAGTAGCAGCAAGAACGTCTTACCGTCCACATCCACGTACAGCCATAGCAGCACCATAGCTCAGGcggcatctgcatctgcatctgccaCCGGCATCTCGGCCGTCTCCATGCACCAACATGCGACAGCACCGCTCCTAATGCCGCCACTGCCCGCTATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATATACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTAAACGCAGAGACAGCGGCCGCCTCTCTGCCGCCAAATGCCGTGGCTAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGCCTTCAGTTTTCGACACGTGCCAATGCCCGACGCCACGAGCGAAATCTGCACCCAAATCTGTTCCAACTGTCGACGGACTCGCCCAACAATACGCCAATCACAAAGCCCACGCCAGCGCTGGCGGCTGCATTGGAGATTCAGCGTGCCGCCGCCGAGGCGGCCACCGAGGAGGCCAGCAAAGCTGCGGGCGCTGCCGGGGGTAATATATCGACCCAAAAGTATCGTCAGGTGGTGATGAATGCCTTCATCAAGTGCGAGGGCGGGGGCTTCAACTATGATACTCCCGAGCAATACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAATTacgagttcctggagcagtACCAGACGATGacctgccgctgctgcgacAAATTCTTCAGTACGTACAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGCTGCTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGAGTCGAAGGCCCTGTTCATTTCGCATCTCAAGAAGCGCAACTGCATCAATCTGTTTCGCGTGCTGAACGCCCTGCGCGGCAAGCAGCCCAACTTCCATCCCCCATCGTCGGACATGGGCTCGTCGTCGTTTGGCGGAGAGACCACCATCGCCAGTCCCACTGTCGCTgcaccgctgctgctggataaCAGCTCGAGCGGCGAGCGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAGCTTTACGAGTGCAAGCTCTGCCCGAAGGGCTTCCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGATTCAGTGCAGCTTCTGCGGGCTGGACTTTGCCGATCCCGTGGACAGGCGCCGCCACTACAACAATATGGACTGCATTGTTCGCCTGCGCTGCATGACATGCGATGCCAAGGTGGAGACGCATCAGCGCTTCCTCGATCATGTCTATCAGGACCATCTCGGGGGCATAAGCAGCGACAATGCCTCCACTGTGAGTGGTAtgggtggcggtggcggtggcaggagcaacagcagtaTTGAGAACTCGCCCGGGAAGCGGAGTCTACTCGGTGCTCTCGGCATTGGGGTTGGCTCCCCCGCCGACGAGTCACGCAGCGGCGGCGGTGCAGCGGCTTCAGCGGCAGCACCCAATCAAACCTCTACACCAAAGCCAACAtcgggtggtggtggtggggcaCCTGGCTCCCTGAATCGCGATGCTGGTGGTGCACCGAAGTCGCAGTATTTCTCCCGAATGCCGCAGGTGTGCCCCATCTGTGGCCAACAgtacaacaactacaacaacgtGCTGCGTCACATGGAATCGAAGCATCCGAACAAGCTCCCGGAGACGTACAAATGTGTGCGCTGCGGCCTGGGCTATCCGAGAATCTCGTATCTCCGAGAGCACATGATCAACTTGCATGGCGTGGACAAGAATCGCCATTCGGGCGGCTTCGAGTACATTGTGAACGCGGATGCCGTGAAGCTGGCCGATGGCAGTACACCGAACGTGTCCACGGGTCGCTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGATGATGACGACGAGGAGACCGGCAGCGTGGCCAAGAAGATACGCCTGGACGatagcagcaacaacagcagtctTGTGGGCGGCGTGGCCAGCCAGCAAAAGGAGTGCCCCATCTGCAACGCGCTGTTCAGCAACAATATCGGCTTGTCCAATCACATGCGCTCGCACTACACGGCCTCCAGTACCGTGAACGCTGCTCTGGTGGCGGCCAATCGTATGACACCCAAATCCCTGACCATAACCGCCGCCCCGGCCACAGAGACGGTCACATCATCGACCTCGGTGGATGTCGACGACGATGAGGGCGTTATAACGCTCGAAACGGGTAATCTTATGGCCAGCCTCAGTGCTGCTAGGGGTGtcacagcagctgctgctgctgctgctgcagctggtgGTGCTGTCCCTCCTGCCATGGTCAATCAGACACCCCAAGAGCAGGCAGTCTTCCGTCGCAGCCTGGATCAGGCGGCAGATCGTCGGTTCCGCCGGATGCGCTGCCGCATCTGTCAGCGGCGTTTTAGCTCAAAGAAATCGTACCGCTACCACATGCTCACCGACCACCACGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGCAATGCAGAGTTCGCCTACGAGAAGGGTCTGAAGGTGCATCTTTTCAAGGTGCACGGACGGGCCATAAAGGACGAGATGATTGTGAAGCAGTTCGAGTGCGATGTCTGTTCGATTGTGTACAGCTCAGAGCTGGAACTGAAGCAGCACAAGAAGAGTGTCCACAAGCTGACAACCGTGTCGGTGTCTGCCTCCGCCTCGGCATCGGCTTCTGCCTCAGCCTCGGCATCCACATCCTCGAAAATCGATGACGATTCGCTGATGATCGAGGAGATCGGTGGCAATAGAAGCCGTcaccatcatcagcagcatcacAGCAAGGCAACTGGCGATCTGGCCGATCAGTCCATCATCTCCGCGGTggctgccaccgccaccgccactgccacaaCGACGCCGTTGTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAACGATTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTATGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCCGACCCAATCGAGTGCACGCTGTGCCGCAAGGTATTCTTCGACCATCAGATGCTGGACAACCATACGCCGACCTGCAACCGAAAGCCGATTACCGCCACGGGAGCGCATCAGCAGGAGCTGCAGACGCAGTCAAATCCGGCGCTGGGTCGGGCCGTATTCAGGCACAAGACTGGCGACGATGATGAAGAGgaagagcaacagcagcagcagcaacagcagcagggtAACCATCAGGAGGATGCTGGCGATGGAGGAGTAGTACCACCAGTGGCCACATCGAGTGCTGGCAGTACCAAAAAGATGCGCATACCGGAGGTGGCCTGTACAATTTGCGGCGCCCGATTCACCGACCAGGAGCACTTCACCAAGCACATACAGAAGCATGAACAGGATCTGTATGTGGACAATCCGCTGGCAGCGATGTTCGACGATGGGCCAGCGGATGCGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAACGGGGAATATGCGTGCGATATGTGCACGAAGACATTCCCCCAAGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGAatatcaacaacaacaacaacaacaattccACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCCCAAccaacagcagaagcaacagcagcagcagagccaacAGCAGAACTCCACGTCCACGgcgaacaacaacaacagcagcagcagcaacaacaacaacaacaacagcagcagcagcaagagcaaaTCAATGAAACGTAAACGTGAATTGAAATGCGAATACTGCCCCTCGACATtcatcagcaacaacaacctGCGACGTCACATGTACGAACTGCACAAGCACGAGGTGAGCAGCCTGCCAGCACCGCCCGTGATTGTGGTAGATGACCCGCTGAGCTGCCGACGTTGTGGCAACATCAAATTCGCGACGAAAGAACTGTGGATCGAGCACAAGCTGGCCGATGCGAAGGTGGTGCGACCATTCTGTCCCTTCCAATGGGGCTGCGACATGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAACAATCATTTGAAGGAGGATGTTATTGTGCCAGTGTCCACACAGGGGGCCCTCGACAGAGAACAACGGGCATCGACAGCATcgtcctcatcatcatcagcctCCGAGGCAACAACATCCAAAGCGAAGGCGTCATCCGTACTGGCGCAGCCAACCAGCGCAGCATTGCAGAAGAAAACGGAGGAAAATGGGGGACTGGAGTCGGCGGAGGCGACGGCAAAGCCTGAGGAGGATGATAGCGAAATGGAGGATGCCGACAGTTCGGACGGCGATGAAGAAAGCTCTGGCACAGgggatgacgacgacgacgatgatgacgatgacggcgacgacgacgatgatgacgatgacgatgaagaCGATGATGAAGGTGAGGGCGAAGACGAGGAGGGTGTGCCCCCACCAACACCTGCGACACAACTGCTGCaaccgcaacagcagcagcaacagcaacataaACACAAAGCAAATATTGACAAGGATGAAGATCTCGTAGAAGAAGTGATCAGCTCTGATGAGGAGCCGGAGGATGGGGGCGAAGTCGAGAGCGAAAGTCAAAGCGATGAGGACGATGACGAAGATGACGATGaagacgacgatgacgaggagGAAGAGGAACAACAGCAGGGACAGGGACCGGGTTCGCAGCCCCTGATGAATGGCAAGTCGAAAGAGCATCAGCAGCAAATCGAAGAGATATTGCCCAGctccgacgacgacgaagagGATGAGGATGGCAATTCTGAGGGCCATACGCTGGCCATTGAAGACATTATTGAAGAAGAATATGATGAAGACGATGATGTGGAGGAGATGGACGATGGTGCAGTCCATCATCCAGATCCCGATGATGTTATCGAAGAGGTCGACGACGATGATGCGGATGATGTGGATGATGAGCAGAATGTCGATGGGGGGGCCACATCGTCGGCCTCATCGTCAGAGAGCGAATCGACATCTACGACCACATCCAATTCGCATTCAACTGGTGAGCGGCGTAAGAAGGCTGGCGACCAGTCGTCAAAACCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCACTGCCTCACAAGCAGCAAGcaatgcaacagcaacagcaacggcaacgacgaCGGCAacagcgacggcgacgacTGTCTCCAGCAATTGTAACAGCAATGCGTCGACCAAATCCTCGAAGCTctctccagcagcagctgcagccgccAACAGCAACCGTCAGAGAAGTGCCGTCGGCGCAGAAAAGGGGGCCAGCGGTAGCAGCAGCAATTGA
Protein Sequence: MCGALVEAERRCCCCCCRRRRHITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNSAAENGAGGGGGHHQQQQPQHHHSENEIDLDKPSAAQILDGIPSLKKRKSLTVYVSPKPQQQQQQQQLQQQQQQQPQQPARLTATATTTSSQQQTLQTLLLQVPTITVSASSTTPASGGGSAAATAAAAAAAATAAAAAAAVSQQQQRQHQYRKYQQQQQQRGKQMMHQQQQQQHHQQLQHHQHLQQKRRQRQTGRRLASQPSGLPGQRKFKPRVYLPLDIAVPPLPPLPAPTTTTTAVGTAAAPAPAPAPGPGPGPGPGPVTIGAPAAAPASHPVLHAAEILPPAAATVVGGNLPLSLPLDFSQSSSKNVLPSTSTYSHSSTIAQAASASASATGISAVSMHQHATAPLLMPPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDIPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDTPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPPSSDMGSSSFGGETTIASPTVAAPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTVSGMGGGGGGRSNSSIENSPGKRSLLGALGIGVGSPADESRSGGGAAASAAAPNQTSTPKPTSGGGGGAPGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINLHGVDKNRHSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDDEETGSVAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITAAPATETVTSSTSVDVDDDEGVITLETGNLMASLSAARGVTAAAAAAAAAGGAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHHVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKKSVHKLTTVSVSASASASASASASASTSSKIDDDSLMIEEIGGNRSRHHHQQHHSKATGDLADQSIISAVAATATATATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECTLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTQSNPALGRAVFRHKTGDDDEEEEQQQQQQQQQGNHQEDAGDGGVVPPVATSSAGSTKKMRIPEVACTICGARFTDQEHFTKHIQKHEQDLYVDNPLAAMFDDGPADAAQFKVEGQNENGEYACDMCTKTFPQVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNNNSTSMLRELHAVGLTPNQQQKQQQQQSQQQNSTSTANNNNSSSSNNNNNNSSSSKSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLSCRRCGNIKFATKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVSTQGALDREQRASTASSSSSSASEATTSKAKASSVLAQPTSAALQKKTEENGGLESAEATAKPEEDDSEMEDADSSDGDEESSGTGDDDDDDDDDDGDDDDDDDDDEDDDEGEGEDEEGVPPPTPATQLLQPQQQQQQQHKHKANIDKDEDLVEEVISSDEEPEDGGEVESESQSDEDDDEDDDEDDDDEEEEEQQQGQGPGSQPLMNGKSKEHQQQIEEILPSSDDDEEDEDGNSEGHTLAIEDIIEEEYDEDDDVEEMDDGAVHHPDPDDVIEEVDDDDADDVDDEQNVDGGATSSASSSESESTSTTTSNSHSTGERRKKAGDQSSKPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKITASQAASNATATATATTTATATATTVSSNCNSNASTKSSKLSPAAAAAANSNRQRSAVGAEKGASGSSSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536223;
90% Identity: iTF_00471788;
80% Identity: -