Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: hang
Assembly: GCA_009870125.2
Location: CM020872.1:15141748-15155483[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.3 23 5.9 1.0 3 23 290 311 289 311 0.93

2 17 0.19 15 6.5 2.7 3 22 419 438 417 438 0.89

3 17 0.00066 0.05 14.2 3.3 1 22 542 563 542 565 0.90

4 17 0.076 5.7 7.8 0.1 2 21 577 596 576 597 0.93

5 17 0.00076 0.058 14.0 0.2 2 23 734 756 733 756 0.95

6 17 0.0022 0.17 12.6 0.1 1 23 764 787 764 787 0.96

7 17 0.00028 0.021 15.4 0.2 2 23 873 894 872 894 0.97

8 17 0.00031 0.024 15.3 2.9 2 23 999 1021 998 1021 0.97

9 17 0.025 1.9 9.3 0.2 2 23 1030 1052 1029 1052 0.95

10 17 0.0067 0.51 11.1 0.2 1 23 1065 1088 1065 1088 0.97

11 17 0.00014 0.01 16.4 1.1 1 23 1169 1191 1169 1191 0.99

12 17 0.0021 0.16 12.6 0.9 1 23 1199 1222 1199 1222 0.96

13 17 1.6 1.2e+02 3.6 0.4 2 19 1230 1247 1229 1248 0.92

14 17 3.5e-05 0.0027 18.2 1.4 3 23 1345 1365 1344 1365 0.98

15 17 0.0096 0.73 10.6 0.1 1 23 1400 1422 1400 1422 0.97

16 17 6.7e-05 0.0051 17.4 0.6 2 23 1506 1528 1505 1528 0.93

17 17 0.0049 0.37 11.5 0.5 3 23 1584 1604 1584 1604 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.3	23	5.9	1.0	3	23	290	311	289	311	0.93
2	17	0.19	15	6.5	2.7	3	22	419	438	417	438	0.89
3	17	0.00066	0.05	14.2	3.3	1	22	542	563	542	565	0.90
4	17	0.076	5.7	7.8	0.1	2	21	577	596	576	597	0.93
5	17	0.00076	0.058	14.0	0.2	2	23	734	756	733	756	0.95
6	17	0.0022	0.17	12.6	0.1	1	23	764	787	764	787	0.96
7	17	0.00028	0.021	15.4	0.2	2	23	873	894	872	894	0.97
8	17	0.00031	0.024	15.3	2.9	2	23	999	1021	998	1021	0.97
9	17	0.025	1.9	9.3	0.2	2	23	1030	1052	1029	1052	0.95
10	17	0.0067	0.51	11.1	0.2	1	23	1065	1088	1065	1088	0.97
11	17	0.00014	0.01	16.4	1.1	1	23	1169	1191	1169	1191	0.99
12	17	0.0021	0.16	12.6	0.9	1	23	1199	1222	1199	1222	0.96
13	17	1.6	1.2e+02	3.6	0.4	2	19	1230	1247	1229	1248	0.92
14	17	3.5e-05	0.0027	18.2	1.4	3	23	1345	1365	1344	1365	0.98
15	17	0.0096	0.73	10.6	0.1	1	23	1400	1422	1400	1422	0.97
16	17	6.7e-05	0.0051	17.4	0.6	2	23	1506	1528	1505	1528	0.93
17	17	0.0049	0.37	11.5	0.5	3	23	1584	1604	1584	1604	0.98

Sequence Information

Coding Sequence: ATGTGCGACAcggcggcaacaacagctacaCCAGTGGTGGCAGCTACAACTGTGGGAGCGGCTTCGGTGTCTGGCACTGGAACCAGCCAGGGAACGGCAGCGGCTACACCAGCGACAGCAGGAGCCACACCGCCAGCTACAACCGCATCGAAACCCGAGCAACAGCGGGCGCGACAAAACTGCTGTCGCCTCTGCATTGCCCCGGCCACGGAATGCATTTCGATCATCAATAGCTATGCGGCCGACAAGGAGCCGCTATCGACAAAAATCCACAACTGTGTGGACATAAAGATAACACCACAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTTAACTCGTGGCAGAGCTTCAAGAATCGGTCGGTTAGCGCACAGAGCAAACAGCGGCAGTGGCTGGAGGCCAACAAGAGTAAGCTCCTCAGCTATTTGGATTTGAACAGTGCCGAGAATGGAGGAGGtcatcagcagcatcaccatcagaaccagcagcagcatcattcGGAGAATGAGATCGATTTGGAGAAGCCATCGGCCGCCCAAATATTGGACGGCATACCCTCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCACTGCCCGCAATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAATCCGATGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTGAACGCAGAGACGGCGGCCGCCTCGCTGCCGCCCAATGCTGTGGCTAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGCCTCCAGTTTTCGACACGTGCCAATGCCAGGCGCCATGAGCGAAATTTGCACCCAAATCTGTTCCAATTGTCGACGGACTCGCCCAACAATACGCCCATCACAAAGCCCACCCCGGCACTGGCGGCTGCATTGGAGATTCAGCGTGCCGCCGCCGAAGCGGCCACCGAGGAGGCCAGCAAAGCTGCAGGCGCTGCCGGGGGTAATATATCGACCCAAAAATACCGTCAGGTGGTGATGAACGCCTTCATCAAGTGCGAGGGTGGGGGCTTCAACTATGACAGTCCCGAGCAGTACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTGGAGCAGTACCAGACGATGACATGTCGCTGCTGCGACAAATACTTCAGTACGTACAAGAACTTTATGGCGCATGTGCGTAAAAAGTATCCGCTGTTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCTCTGTTCATTTCCCATCTCAAGAAGCGCAACTGCATCAATCTATTTCGTGTGCTGAACGCCCTGCGCGGCAAGCAGCCAAATTTTCACCCCTCATCGGACATTGGATCGTCGTTCGGTGGAGagaccaccaccaccaccacaaccatCACCAGTCCCAATGTCGTTgtaccgctgctgctggataaCAGCTCGAGCGGCGAACGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTTTACGAGTGCAAACTCTGCCCGAAGGGCTTCCGCACCAAGCACGAGTTTCGCACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAACTCGATTCAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCCGTCGACAGGCGCCGCCACTACAACAACATGGACTGCATTGTTCGCCTACGCTGCATGACGTGCGACGCCAAGGTGGAGACGCATCAGCGTTTTCTCGATCATGTCTATCAAGATCATCTGGGGGGCATAAGCAGCGACAATGCCTCCACTGTGAGTGGAttgggcggcggcggaggcggcggcggcaggagcagcagcagtattGAGAACTCGCCCGGGAAGCGGAGTCTACTAGGGGCTCTCGGGATCGGTGTTGGCTCCCCCGCCGATGAGTCACGCACCGGCAGTGCAGCGGCGACAGCGGCAGCCGTAGCACCCAATCAAACCTCCACGCCAAAGCCGACATCGGGAGGTGGGGCGGGCACAACACCTGGCTCCCTGAATCGTGATGCTGGTGGTGCACCGAAATCGCAGTATTTTTCACGAATGCCCCAGGTATGCCCCATCTGTGGCCAACAgtacaacaactacaacaacgtGCTGCGTCACATGGAATCGAAGCATCCAAACAAACTCCCGGAGACCTACAAATGTGTGCGCTGCGGCCTGGGCTATCCGAGAATCTCGTATCTGCGAGAGCATATGATCAACGTGCATGGCGTGGACAAGAATCGAAATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTGAAGCTGGCCGATGGCAGTACACCGAATGTGTCCACGGGTCGTTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGACCGGCAGCATGGCCAAGAAGATACGCCTGGACgatagcagcaacaacagcagtctGGTGGGTGGGGTGGCCAGCCAGCAAAAGGAATGCCCCATCTGCAATGCACTGTTTAGCAACAATATTGGCCTGTCGAATCACATGCGCTCACATTACACGGCCTCGAGTACCGTGAACGCTGCTCTGGTGGCGGCCAATCGCATGACACCCAAATCCCTGACCATAACCGCCGCCCCAGCCATAGAGACGGTCACATCATCGGCCTCAGTCGATGTTGACGATGACGAGGGCGTTATGCCGCTCGAATCCGGAAATATTATGGCCAGCGTCAGCGGTGGCAGAGGTGTTGCTTCTGTTTCAGCTATTGCTGCTGTGCCTCCTGCCATGGTTAATCAGACGCCTCAAGAGCAGGCCGTCTTTCGTCGCAGCCTGGACCAGGCGGCGGATCGTCGCTTCCGCCGGATGCGTTGCCGCATCTGTCAGCGGCGTTTTAGCTCAAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTTATCAAGTGCAAGCTGTGCAATGCAGAGTTTGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAGGATGAGATGATTGTGAAGCAGTTTGAGTGCGATGTCTGTTCGATTGTCTACAGCTCGGAGCTGGAACTGAAGCAGCACAAGCAGAGCGTCCATAAGCTGACATCCGTGTCGGTGTCTGCATCCGCCTCGGCatcggcttcggcttctgcCTCGGCATCCACATCCTCGAAAATCGATGATGATTCACTGATGATGGAGGACATCGGTGGCAATAGAAGCCGtcaccatcatcagcagcacaGCAAGGCATCTGGCGATCTGGCCGATCAGTCCATCATCTCCGCCAtggctgccaccgccactgccagtgccacaaCGACGCCGCTCTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGATGAGTTCGACTCGAACGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTATGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCGGACCCAATCGAGTGCATGCTGTGCCGCAAGGTGTTCTTTGACCATCAGATGCTGGACAATCATACGCCGACCTGCAACCGTAAGCCAATTACCGCCACGGGGGCGCatcagcaggagctgcagacGCAGTCAAATCAGCCGCAAGGTCGGGCCGTATTTAGGCACAAGACTggcgacgatgacgacgaggaagagcaacagcagcatcaccagcagcagcaacagcgtaACCATCAGGAGGATGCTGGCGATGGaggagcagtagcagcagcagctgctgccgctgccgctgccacatcGAGCGGCACCATCAGCGGTGTCAGTACCAAAAAGATGCGCATACCGGAGGTGGCCTGTACAATTTGTGGCGCCAGATTCACTGATCAGGAGCACTTTAGCAAGCACATACAGAAGCATGAACAGGATCTATATGTGGATAATCCGCTGGCAGCGATGTTCGACGATGGGCCGGCGGATGCGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAACGGGGAATACGCGTGCGATATGTGCACGAAGACATTCCCCCTGGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGaatatcaacaacaacaacaacaacaattcgGTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCCCaaccaacaacagaagcaacagcagcagaactcCACGTCCACgccgaacaacaacagcagcagcaacaacaacaacagcaacagcagcaagagcagaTCAATGAAGCGTAAACGTGAATTGAAATGCGAATACTGCCCCTCGACAttcatcagcaacaacaacctgcGACGCCACATGTACGAACTGCATAAGCACGAGGTGAGTAGCCTGCCAGCACCGCCCGTGATTGTGGTGGATGACCCGCTCTGCTGTCGACGTTGTGGCAATATCAAATTCGAGACGAAAGAACTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTGCGACCATTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTCATTGTGCCAGTGGCCACACAAGGGGCCATCGACAGAGAACGAGCATCgacagcatcatcatcatcatcgtcagcatcggcagcatcgGCTTCGGCATCCGAGGCAACAACATCCAAAGCAAAGGCGTCGTCCGTACTGGCGGAGCAACCCGGTGCCATACTGCAGAAGAAAACGGAGGAAAATGGTGGACTGGATGGAGCAGAGGCGGCGGTAAAGGCAGATGAAGATGATAGCGATATGGAGGATGCCGACAGTTCAGACGGTGATGAAGAAAGCTCTGGCACAggggatgaagacgacgacgacgatgatgacgacgacgacgacgacgacgacgacgatgatgacgacgaagATGAGGGCGAAGACGAGGAGGGTGTGCCCCCACCAACACCTGCCACACAACtgttgccacagcagcaggagcagcagcagcaacacaaacacaaagccAATATTGACAATGATGAAGATCTCGTCGAAGAAGTGATCAGCTCTGATGATGAAGAGCCTGAGGATGGAGGGGAAGTCGAGAGCGAAAGTCAAACAGAAAGCGAAgaggacgatgacgaggatgacgatgaagacgatgacgacgaggaagaggaacagggacaggaacaggaacaggccTCGCAGCCCCTGGTGAATGGCAAGTCGAAAGAGCATCAACAGCAAATCGATGAGATATTGCCCAGctccgacgacgacgaagtgGGGGATGGCAATTTAGATGGCCATCTGATGGCCATTGATGACATTATTGAAGAAGAATTTGATGAAGACGATGATATGGAGGAGGTGGACGATGGTGCAGTCCATCCAGATCCCGATGATGTTATCGAAGAGGTCGACGACGATGATGCGGATGAGGTGGATGAAGAGCACAATGTCGATGGGGGCGGCACATCATCGGCCTCATCGTCAGAGAGTGAATCAACATCCACGACCACATCCAATTCGCATTCAACTGGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCTCTGCCTCACAAGCAACAAgcaatgcaacagcaacagcaacggcaacggcaacgacgacgactgtGTCGAGCAATTGTAA
Protein Sequence: MCDTAATTATPVVAATTVGAASVSGTGTSQGTAAATPATAGATPPATTASKPEQQRARQNCCRLCIAPATECISIINSYAADKEPLSTKIHNCVDIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNSAENGGGHQQHHHQNQQQHHSENEIDLEKPSAAQILDGIPSLKKRKSLTVYPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDVPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDSPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPSSDIGSSFGGETTTTTTTITSPNVVVPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTVSGLGGGGGGGGRSSSSIENSPGKRSLLGALGIGVGSPADESRTGSAAATAAAVAPNQTSTPKPTSGGGAGTTPGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRNSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDEEETGSMAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITAAPAIETVTSSASVDVDDDEGVMPLESGNIMASVSGGRGVASVSAIAAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKQSVHKLTSVSVSASASASASASASASTSSKIDDDSLMMEDIGGNRSRHHHQQHSKASGDLADQSIISAMAATATASATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECMLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTQSNQPQGRAVFRHKTGDDDDEEEQQQHHQQQQQRNHQEDAGDGGAVAAAAAAAAAATSSGTISGVSTKKMRIPEVACTICGARFTDQEHFSKHIQKHEQDLYVDNPLAAMFDDGPADAAQFKVEGQNENGEYACDMCTKTFPLVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNNNSVNNSTSMLRELHAVGLTPNQQQKQQQQNSTSTPNNNSSSNNNNSNSSKSRSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLCCRRCGNIKFETKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVATQGAIDRERASTASSSSSSASAASASASEATTSKAKASSVLAEQPGAILQKKTEENGGLDGAEAAVKADEDDSDMEDADSSDGDEESSGTGDEDDDDDDDDDDDDDDDDDDDEDEGEDEEGVPPPTPATQLLPQQQEQQQQHKHKANIDNDEDLVEEVISSDDEEPEDGGEVESESQTESEEDDDEDDDEDDDDEEEEQGQEQEQASQPLVNGKSKEHQQQIDEILPSSDDDEVGDGNLDGHLMAIDDIIEEEFDEDDDMEEVDDGAVHPDPDDVIEEVDDDDADEVDEEHNVDGGGTSSASSSESESTSTTTSNSHSTGASPVSHQKPFPQWSKNLCLTSNKQCNSNSNGNGNDDDCVEQL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536223;
90% Identity: iTF_00574991;
80% Identity: -