Basic Information

Insect: Drosophila kikkawai
Gene Symbol: ham
Assembly: GCA_018152535.1
Location: NW:26726542-26753992[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0057 0.34 11.2 0.0 2 23 203 225 202 226 0.92

2 9 0.0029 0.17 12.1 2.1 1 23 232 255 232 255 0.94

3 9 1.4e-07 8.3e-06 25.7 1.7 1 23 261 284 261 284 0.96

4 9 8.7e-07 5.2e-05 23.2 1.6 1 23 290 312 290 312 0.97

5 9 2.3e-05 0.0013 18.7 3.3 1 23 318 340 318 340 0.97

6 9 0.00021 0.012 15.7 1.7 2 21 348 367 347 368 0.94

7 9 5.2e-09 3.1e-07 30.2 1.3 1 23 863 885 863 885 0.99

8 9 3.7e-07 2.2e-05 24.3 0.5 1 23 891 914 891 914 0.97

9 9 5.9e-06 0.00035 20.6 1.3 1 23 920 942 920 942 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0057	0.34	11.2	0.0	2	23	203	225	202	226	0.92
2	9	0.0029	0.17	12.1	2.1	1	23	232	255	232	255	0.94
3	9	1.4e-07	8.3e-06	25.7	1.7	1	23	261	284	261	284	0.96
4	9	8.7e-07	5.2e-05	23.2	1.6	1	23	290	312	290	312	0.97
5	9	2.3e-05	0.0013	18.7	3.3	1	23	318	340	318	340	0.97
6	9	0.00021	0.012	15.7	1.7	2	21	348	367	347	368	0.94
7	9	5.2e-09	3.1e-07	30.2	1.3	1	23	863	885	863	885	0.99
8	9	3.7e-07	2.2e-05	24.3	0.5	1	23	891	914	891	914	0.97
9	9	5.9e-06	0.00035	20.6	1.3	1	23	920	942	920	942	0.98

Sequence Information

Coding Sequence: ATGGAGCACTTCTTCAAGGATCCCTCCCAGGCGGAGCAGATTCTGCAGGAGTGGGCGAGACGCCGGGAACCCATCAGTGAACTGGACATCCGGGAAAGTGGTGTCTATGCCAAGACATCCTTGGAAAGGGGCACCCGCTATGGTCCCTTTCCCGTGAAGCTCTGCCATCAGCCCAACGATTCACAGCTGGCCTGGAGGGCCCATGCCGAGCACTTTAATGGCTGGCTAGAGCCCACATCTGATGTTTCCGGTTGGCTAAAGAAAATCCGCGTCATAGATGACAACGAATTTATAGCCAAGGCCAATCTGGAGAGTTTCATTAATGGCGGTTGTctATATTACGAAACGAATCGTTATGTGAGTGCCGGCAGCGAAATGATTGTGGATGGTCGACCCAAGAGTCCCGTGCAGATCAATGAGAGCTTCATGAACGGCGGCGGGGTCCTGGCCGCAGCTGCAGCAGTGGCCGCAGTGGCTGCCGCCACATCTTCGTCGGCGGGGTCGGGTGGAAAGAGCGGCAAGGGGTCATCGGTGCCCAGCGATGATCGCAGTGATCGTGATAATGGTGATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTGTTGGACGATCATCTGGTGGTTGCCCATCATTTCAAGCAGGACGACTACTCCTGCAAGCTCTGCCCTCTGCGATTCTGCCATCGTCCTTTGCTCATCAAGCACGAAGCGATCTCCCACAATAATATAAGGAAATATTCCTGCGAGAATTGCAGCAAGGTTTTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCACCCTTGTCCAGAGTGCGGAAAGACGTTCGGTACCTCGTCGGGGCTGAAGCAGCACCAGCACATCCACAGCAGCGTGAAACCCTTCGCCTGCGAGGTGTGCTCCAaggcgtatacgcaattcTCGAACCTGTGCCGCCACAAGCGGATGCACGCCACCTGCCGCACGCAGATCAAGTGCGACAAGTGCAATCAGAGCTTCAGCACCTTGACCTCGCTGACCAAGCACAAAAAGTTCTGTGATTCAACGGGCTCGtaccgccagcagcagcatcagcatcagcaccagcaGTCGCCGCTAAGTCGCCACCacccgcatccgcatccgtaCCAGCCGCATCCGCAGCATCCTCACCAGCATCCGGCCTCCAGGCATCCGGCAGCCGCCACAGTCACATCCGCCTCTGCAGTGCCTGCGGGAGGAGAGTCTACGGGAGGATCTGCCACTTCGTCTTCGTCTGCCACCGCTGCCGTTGTTGCCGCCATGTCAACGCCGCCGAATCCCTTCCTGATGTTCCGCACGGGAGCGCCATTCTTCCCCGGCTTCCCGCCGTACGGCCTGCCGGGAATGTTCCCGCAGAGTCCACTGAGAGCCGCCAACTTCCCGCTTTTCTTCCCCAATCCCCCCATGGACATGGGCTGCGGCATGCCCGGCATGACCTCGCCGAACTCTGCCTTCCGGCAGCAGTTGCCCTTCGGCATGGGTCCCATGGAGGGACAGGGAGGCGGAGGAGGTTCACCACACCAGACGGATGCCCAGTTAAAGGCGGAGGAAGAGGAGCACAACTTGTCTGTGAAGTCGGAGGATAAGCTCAAGAGAGAGCCCCTGCTGAATGTGTCCGAAGGCGATGAGGAGGAGGctgaggacgaggaggaggacgacgcTGAGAGTCGTCATAGCAATCTGGACATGACAATCAAATcagaggaggagaaggaggccAAGGTCAAGAAAGAGGAGAAGAACGAGGATCAAAGTGAAATGAAATCTGAACCCGAGAGACTGGGCAGTCCCGATCAGCAGCAGGTGGAGGATGATAGGAAATCCATTGATATTGTCAGCACGCCACCGCCCACGGATGCTCCTACTGCCGGCGATGCCCCGCTGGATCTCTCCATTTGCCGCAAGCGCCTGTCCGGTTACTTCCCGGCTCCGCCTGGCAGTCCTGGTCTGCTCTCCTCCAGCCTTATGCGTTTCCTGCCCTCCACCAGAACCGAGGAGGATGAGACAGATGGCGAGCCGCCGCTCAAGACGCGGAAATCCCACAGTTCCGGCGAGTCCTCGACGTCGCAAAAGTCCTACAAGGGCAGCAGTCCCACGCCCACAGCCTCGCCGGGGCCCACACCCTCACCCTCACCTCCCACCAGTGCCGGGGGAGAGCTGAGCAGCATGTCCgagggagctggagctgggtcAGGAACGGGACTGGCTgccgcagcggcagcagcagcggctgcaGCGGCCGCCGGAGCCGCGGAGGCTGCCCTGGCCGCCCACTATAACCGCCAGAATCCACCCATACACCCGATGGTGCTGGAGGAAATCTATCGCAGccggttttcttttttatgcccAGCGGGCGGACGGCCCGGCATTGAGGCTTTGCTGGCGGGAGCCGCCGCCGGCGCCGCCTCAAAGCGGCCGCTTCCGCCCGTTAAGTTCGCCACAGGGGCAACTGTGGGCTCCTCCGTGGGTCATCCGCTGAAGACAAAGGATCGTTATACCTGCAAGTTTTGCGGCAAGGTGTTCCCCCGCTCGGCCAATCTCACCCGGCACCTGAGGACGCACACCGGCGAGCAGCCGTATCCGTGCAAATACTGCGACCGGGCCTTTAGCATCTCCTCCAATCTGCAGCGCCACGTGAGGAATATCCACAACAAGGAGCGACCTTTTCGCTGCGAACTCTGCGACCGATCCTTTGGCCAGCAGACGAATCTCGATCGGCATGTGAAGAAGCACGAGGCGGAGGGCAGCAACTTCCGGGACTCGCCCAGCTCTGCCTCGGGCGTGGCCGAGCGGGAGGAGTATTTCGATGAGATCAGGACCTTCATGAACAGGGTGTATACGCCAAACAGCCTGGCGGGAAACGAGGGGGACACCGAGGACGATGACCAGTCCTCGGTGATCCTGGAGAAGAAGTCGCACctcaacaacaataacaacagcagccacatTAGCAACAATAATCCCAAGTTGCTGTATTCGTGA
Protein Sequence: MEHFFKDPSQAEQILQEWARRREPISELDIRESGVYAKTSLERGTRYGPFPVKLCHQPNDSQLAWRAHAEHFNGWLEPTSDVSGWLKKIRVIDDNEFIAKANLESFINGGCLYYETNRYVSAGSEMIVDGRPKSPVQINESFMNGGGVLAAAAAVAAVAAATSSSAGSGGKSGKGSSVPSDDRSDRDNGDIDFTDDENGFDIRCEVCDKVYPDLELLDDHLVVAHHFKQDDYSCKLCPLRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRTQIKCDKCNQSFSTLTSLTKHKKFCDSTGSYRQQQHQHQHQQSPLSRHHPHPHPYQPHPQHPHQHPASRHPAAATVTSASAVPAGGESTGGSATSSSSATAAVVAAMSTPPNPFLMFRTGAPFFPGFPPYGLPGMFPQSPLRAANFPLFFPNPPMDMGCGMPGMTSPNSAFRQQLPFGMGPMEGQGGGGGSPHQTDAQLKAEEEEHNLSVKSEDKLKREPLLNVSEGDEEEAEDEEEDDAESRHSNLDMTIKSEEEKEAKVKKEEKNEDQSEMKSEPERLGSPDQQQVEDDRKSIDIVSTPPPTDAPTAGDAPLDLSICRKRLSGYFPAPPGSPGLLSSSLMRFLPSTRTEEDETDGEPPLKTRKSHSSGESSTSQKSYKGSSPTPTASPGPTPSPSPPTSAGGELSSMSEGAGAGSGTGLAAAAAAAAAAAAAGAAEAALAAHYNRQNPPIHPMVLEEIYRSRFSFLCPAGGRPGIEALLAGAAAGAASKRPLPPVKFATGATVGSSVGHPLKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGSNFRDSPSSASGVAEREEYFDEIRTFMNRVYTPNSLAGNEGDTEDDDQSSVILEKKSHLNNNNNSSHISNNNPKLLYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561894;
90% Identity: iTF_00489516; iTF_00485283; iTF_00488803; iTF_00524551; iTF_00491657; iTF_00478154; iTF_00593995; iTF_00492374; iTF_00490216; iTF_00613624; iTF_00541211;
80% Identity: -