Basic Information

Insect: Drosophila bunnanda
Gene Symbol: ham
Assembly: GCA_008042815.1
Location: VNKE01000174.1:66560-91060[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.02 1.4 9.4 0.0 2 23 310 332 309 333 0.91

2 9 0.0019 0.14 12.6 2.5 1 23 339 362 339 362 0.94

3 9 1.5e-07 1.1e-05 25.5 1.7 1 23 368 391 368 391 0.96

4 9 9.5e-07 6.7e-05 23.0 1.6 1 23 397 419 397 419 0.97

5 9 2.5e-05 0.0017 18.6 3.3 1 23 425 447 425 447 0.97

6 9 0.00022 0.016 15.6 1.7 2 21 455 474 454 475 0.94

7 9 5.6e-09 4e-07 30.0 1.3 1 23 985 1007 985 1007 0.99

8 9 4e-07 2.9e-05 24.2 0.5 1 23 1013 1036 1013 1036 0.97

9 9 6.4e-06 0.00045 20.4 1.3 1 23 1042 1064 1042 1064 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.02	1.4	9.4	0.0	2	23	310	332	309	333	0.91
2	9	0.0019	0.14	12.6	2.5	1	23	339	362	339	362	0.94
3	9	1.5e-07	1.1e-05	25.5	1.7	1	23	368	391	368	391	0.96
4	9	9.5e-07	6.7e-05	23.0	1.6	1	23	397	419	397	419	0.97
5	9	2.5e-05	0.0017	18.6	3.3	1	23	425	447	425	447	0.97
6	9	0.00022	0.016	15.6	1.7	2	21	455	474	454	475	0.94
7	9	5.6e-09	4e-07	30.0	1.3	1	23	985	1007	985	1007	0.99
8	9	4e-07	2.9e-05	24.2	0.5	1	23	1013	1036	1013	1036	0.97
9	9	6.4e-06	0.00045	20.4	1.3	1	23	1042	1064	1042	1064	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCCAGCGGCGACGACTTCGATCCCAGTGCCAGTGGCGTGCGTCACCACCATCGCCTGGATCACCACCACCTGGATCACCATCACCTGGACCATCACCATCTCGATCTCAGTGCCCGGACTCAGGGCTTTACTGGCTTGCCCTTGGAGCAGGAAGGATCTCCAACcagggaggaggagcaccaccaccaccgccagcaTCCgttgcagcagctccagcagccaccgccgcccacgTTGCCCTTGGACTCGGCAGCGGCTGCCATTGCCAGTGAGTCCGGCATGGAGCACTTCTTCAAGGACCCCGCCCAGGCGGAGCAGATCCTGCAGGAGTGGGCCAGGCGCAGGGAACCGATCAGTGATCTGGACATCCGCGAGAGCGGTGTCTATGCCAAGACCTCCCTGCAGCGGGGCACCCGGTATGGCCCTTTTCCCGTCAAGCTCTGCCATCAGCCTAATGATATGCAACTGGCCTGGAAGGCCCATGCCGAGCACTTTAATGGCTGGCTAGAGCCCACATCCGATGTCTCCGCTTGGCTTAAGAAAATCCGCGTCATAGAGGACACTGGCATCATAGCCAAGGCCAATCTGGAGAGTTTCATTAATGGCGGTTGTctttattACGAAACGAATCGTTATGTGAGTGCCGGCAGCGAAATGATTGTGGATGGGCGACCCAAGAGTCCCGTGCAGATCAACGAGAGCTTCATGGCCAGCGGCGGTGTCCTggccgcagctgcagcagccgcggcCGCGGTGGCCGCCGCCACATCCTcgtcgggatcgggatcgggatcgggcgGCAAGAGTGGCAAGGGATCATCGGTGCCCAGCGATGATCGCAGTGATCGCGATAATGGTGATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTGCTGGACGGTCATCTGGTGGTTGCCCATCATTTCAAGCAGGACGACTACTCCTGCAAGCTCTGTCCGCAGCGATTCTGCCATCGTCCTTTGCTCATCAAGCACGAAGCGATCTCCCACAACAACATAAGGAAATATTCCTGCGAGAACTGCAGCAAGGTTTTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCACCCCTGTCCGGAGTGCGGAAAGACCTTTGGTACCTCGTCGGGGCtgaagcagcaccagcacatCCACAGCAGCGTGAAGCCGTTCGCCTGCGAGGTGTGCTCCaaggcgtatacgcaattctCGAACCTGTGCCGCCACAAGCGGATGCACGCCACCTGCCGCATGCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACGCTAACCTCGCTGACCAAGCACAAAAAGTTCTGTGATTCGACGGGCTCCtaccgccagcagcagcagcagcatcagcatcagcaccagcagtcGCCGCTGAGTCGCcaccatccgcatccgcatccgtacCAGCAGCACCCGCATCCACACCAGCATCCGGCCTCCGCACATCCCGCCACCGCCACAGCCACATCGGGTTCCGCAGGGCCAGCGGGGGGAGTAGAGTCCACGGGAGGAGGATCTGCCGCTGCATCTTCGTCTGCCACCGCTGCCGTCGTTGCCGCCATGTCGACGCCGCCGAATCCCTTCCTGATGTTCCGCACGGGAGCGCCGTTCTTCCCCGGCTTCCCGCCATACGGCCTGCCTGGAATCTTCCCGCAGAGTCCCCTGAGAGCCGCCAATTTCCCGCTTTTCTTCCCCAATCCCCCCATGGACATGGGCTGCGGCATGCCGGGCATGACCTCGCCGAACTCCGCCTTCCGGCAGCAGTTGCCCTTCGGCATGGGACCCATGGAGGGGCAGGGTGGAGGTGGCGGTTCGCCACGCCAAACGGATGCCCAGCTaaaggcggaggaggaggaggagcacaaCTTGTCGGTCAAGTCGGAGGACAAGCTCAAGCGGGAGCCTCTGCTGAATGTGTCCGAaggcgacgaggaggaggctgaggacgtggaggaggaggaggaggaggaggaggctgagAGTCGTCACAGCCACCTAGAAATGATAATCAAgtcggaggaggagaaggaggccaAGGtcgagaaggaggagcagacCGAGCAACAGGCCGCGATGAAGTCAGAGCCCGAGAGACCCGACAGTCCCGATCAGCAGCAGGTGGATGATGATAGGAAATCCATTGATATTGTGAGCACACCACCGCCCACGGATGCTCCTACTGCCACCGGCGGCGGCGATGCCCCCTTGGATCTCTCCATTTGCCGCAAGCGCCTGTCCGGCTTCTTTCCGGCCCAACCTGGCAGTCCTGGCCTGCTCTCCTCCAGCCTGATGCGTTTCCTGCCCTCCACCAGAACCGAGGAGGATGAGACTGATGGCGAGCCGCCGCTCAAGCTGCGCAAGTCACACAGTTCCGGCGAGTCCTCGACCTCGCAAAAGTCCTACAAGGGCAGCAGTCCCACGCCCACAGCCTCGCCGGGGCCCACGCCCTCGCCCTCACCGCCCACCAGTGCCGGTGGCGAGCTGAGCAGCATGTCCGAGGGAGCGGGAGTGGGATCCGGGGCCGGTTCGGGATCTGGACTCGCagccgcagcggcagcagcagccgctgcagcggccGCCGGTGCCGCCGAAGCTGCTCTGGCCGCCCACTATACCCGCCAGAATCCACCCATACACCCGATGATGCTGGAGGAGATCTATCGCAGccggttttcttttttatgccCGGCGGGCGGACGGCCCGGCATTGAGGCTTTGCTGGCGGGAGCCGCCGCCGGCGCCGCCTCAAAGCGGCCGCTTCCGCCCGTTAAGTTCGCCACCACCGGGGCAACGGGCTCCTCCGTGGGCCATCCACTGAAGACCAAGGACCGGTATACGTGCAAGTTCTGCGGCAAGGTGTTCCCCCGATCGGCGAATCTCACGCGACACCTGAGGACGCACACCGGCGAGCAGCCGTATCCGTGCAAGTACTGCGACCGGGCCTTCAGCATCTCCTCCAACCTCCAGCGCCACGTGCGGAATATCCACAACAAGGAGCGCCCCTTCCGCTGCGAACTCTGCGACCGTTCCTTTGGCCAGCAGACGAATCTCGATCGGCATGTGAAGAAGCACGAGGCGGAGGGCAGCAACTTCCGGGACTCGCCCAGCTCCGCCTCGGGCGTCGCCGAGCGGGAGGAGTACTTCGATGAGATCAGGACCTTCATGAACAGGGTCTACACCCCGAATAGCCTGGCTGGCAACGAAGGGGACACCGAGGAGGATGACCAGTCCTCGGTGATCCTCGAGAAGTCGCacctcaacaacaacaacaacaacaatagcagtCACATTAGCAACAACAATCCCAAGTTGCTGTACTCGTGA
Protein Sequence: MLFDRYVISGSSGDDFDPSASGVRHHHRLDHHHLDHHHLDHHHLDLSARTQGFTGLPLEQEGSPTREEEHHHHRQHPLQQLQQPPPPTLPLDSAAAAIASESGMEHFFKDPAQAEQILQEWARRREPISDLDIRESGVYAKTSLQRGTRYGPFPVKLCHQPNDMQLAWKAHAEHFNGWLEPTSDVSAWLKKIRVIEDTGIIAKANLESFINGGCLYYETNRYVSAGSEMIVDGRPKSPVQINESFMASGGVLAAAAAAAAAVAAATSSSGSGSGSGGKSGKGSSVPSDDRSDRDNGDIDFTDDENGFDIRCEVCDKVYPDLELLDGHLVVAHHFKQDDYSCKLCPQRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGSYRQQQQQHQHQHQQSPLSRHHPHPHPYQQHPHPHQHPASAHPATATATSGSAGPAGGVESTGGGSAAASSSATAAVVAAMSTPPNPFLMFRTGAPFFPGFPPYGLPGIFPQSPLRAANFPLFFPNPPMDMGCGMPGMTSPNSAFRQQLPFGMGPMEGQGGGGGSPRQTDAQLKAEEEEEHNLSVKSEDKLKREPLLNVSEGDEEEAEDVEEEEEEEEAESRHSHLEMIIKSEEEKEAKVEKEEQTEQQAAMKSEPERPDSPDQQQVDDDRKSIDIVSTPPPTDAPTATGGGDAPLDLSICRKRLSGFFPAQPGSPGLLSSSLMRFLPSTRTEEDETDGEPPLKLRKSHSSGESSTSQKSYKGSSPTPTASPGPTPSPSPPTSAGGELSSMSEGAGVGSGAGSGSGLAAAAAAAAAAAAAGAAEAALAAHYTRQNPPIHPMMLEEIYRSRFSFLCPAGGRPGIEALLAGAAAGAASKRPLPPVKFATTGATGSSVGHPLKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGSNFRDSPSSASGVAEREEYFDEIRTFMNRVYTPNSLAGNEGDTEEDDQSSVILEKSHLNNNNNNNSSHISNNNPKLLYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561894;
90% Identity: iTF_00527467;
80% Identity: -