Basic Information

Insect: Drosophila seguyi
Gene Symbol: ham
Assembly: GCA_008042675.1
Location: VNJU01001239.1:43516-69104[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0062 0.45 11.0 0.0 2 23 318 340 317 341 0.92

2 9 0.0032 0.23 11.9 2.1 1 23 347 370 347 370 0.94

3 9 1.5e-07 1.1e-05 25.5 1.7 1 23 376 399 376 399 0.96

4 9 9.5e-07 6.9e-05 23.0 1.6 1 23 405 427 405 427 0.97

5 9 2.5e-05 0.0018 18.5 3.3 1 23 433 455 433 455 0.97

6 9 0.00023 0.016 15.5 1.7 2 21 463 482 462 483 0.94

7 9 5.6e-09 4.1e-07 30.0 1.3 1 23 997 1019 997 1019 0.99

8 9 4e-07 2.9e-05 24.2 0.5 1 23 1025 1048 1025 1048 0.97

9 9 6.4e-06 0.00047 20.4 1.3 1 23 1054 1076 1054 1076 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0062	0.45	11.0	0.0	2	23	318	340	317	341	0.92
2	9	0.0032	0.23	11.9	2.1	1	23	347	370	347	370	0.94
3	9	1.5e-07	1.1e-05	25.5	1.7	1	23	376	399	376	399	0.96
4	9	9.5e-07	6.9e-05	23.0	1.6	1	23	405	427	405	427	0.97
5	9	2.5e-05	0.0018	18.5	3.3	1	23	433	455	433	455	0.97
6	9	0.00023	0.016	15.5	1.7	2	21	463	482	462	483	0.94
7	9	5.6e-09	4.1e-07	30.0	1.3	1	23	997	1019	997	1019	0.99
8	9	4e-07	2.9e-05	24.2	0.5	1	23	1025	1048	1025	1048	0.97
9	9	6.4e-06	0.00047	20.4	1.3	1	23	1054	1076	1054	1076	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCCACTGGCGACGACTTCGATCCGAGTGCTAGTGCTGTGCGTCACCACCATCGGTTGGATCACCATCACCTGGATCACCACTtggatcatcatcatcaccatctcGATCTTAGTGCCAGGACTCAGGCCTTTGCTGGTCTGCCTTTAGAGCAGTCCCTTGAGGAAAGTTCTCCCACcagggaggagcagcagcagcatcatcatcaacaccaccaccaccaccaccaccagttgcagcagctccagcagccaCCGCCGCCCACGTTGCCCCTGGACTCGGCAGTAGCCACCGGTGAGTCCGGCATGGAGCACTTTTTCAAGGATCCCGCCCAGGCGGAGCAGATCCTGCAGGAGTGGGCAAGGCGCCGGGAACCCATCAGTGATCTGGACATCCGGGAGAGCGGTGTCTTTGCCAAGACCTCCCTGCAGAGGGGCACCCGCTATGGTCCCTTTCCCGTCAAGCTCTGCCATCAGCCCAACGATTCACAGCTGGCCTGGAAGGCCCATGCCAAGCACTTTAATGGCTGGCTAGAGCCCACATCCGATGTCTCAGCTTGGCTAAAGAAAATCCGCGTCATAGAGGACCACGAAATGATAGCCAAGGCCAATCTGGAGAGTTTCATTAATGGCGGTTGTctcTATTACGAAACGAATCGTTATGTGAGTGCCGGCAGCGAAATGATTGTGGATGGTCGACCCAAGAGTCCCGTGCAGATCAATGAGAGCTTCATGGCCGGCGGCGGTGTCCTGgccgcagctgcagcagccgcggccgccgttgccgctgccacATCCTCCTcaggatcgggatcgggatcgggcgGAAAGAGCGGGAAGGGTTCATCGGTGCCCAGCGATGATCGCAGTGATCGTGATAATGGTGATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTGTTGGACGATCATCTGGTGGTTGCCCATCATTTCAAGCAGGACGACTACTCCTGCAAGCTCTGTCCGCTGCGATTCTGCCATCGTCCTTTGCTCATCAAGCACGAAGCGATCTCCCacaataatataagaaaatattcctGCGAGAATTGCAGTAAGGTTTTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCACCCCTGTCCGGAGTGCGGAAAGACGTTCGGTACCTCGTCCGGGCTgaagcagcaccagcacaTCCACAGCAGCGTCAAGCCCTTCGCCTGCGAGGTGTGCTCCaaggcgtatacgcaattcTCGAACCTCTGCCGCCACAAGCGGATGCATGCCACCTGCCGCATGCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACTTTGACCTCGCTGACCAAGCACAAAAAGTTCTGTGATTCGACGGGCTCGtaccgccagcagcagcatcagcatcagcagtcGCCGCTGAGTCGCCaccatccgcatccgcatccgtatcagcagcatccgcatccgcagcATCCCCACCAGCTACCCGCTTCGACGCATCCGGCAGCTGCCACAGCCACATCGGTGGGATCCGCAGGACCAGCGGGAGGAGACTCCACGGGAGGATCAGTCACTTCGTCATCGTCGTCTGCCACCGCTGCCGTTGTTGCCGCCATGTCAACGCCACCGAATCCCTTCCTCATGTTCCGCACGGGAGCCCCGTTCTTCCCCGGCTTTCCGCCCTACGGACTTCCGGGTATCTTCCCGCAGAGTCCCCTGAGAGCCGCCAATTTCCCGCTTTTCTTCCCGAATCCCCCCATGGACATGGGCTGCGGCATGCCGGGCATGACCTCGCCGAACTCTGCCTTTCGGCAGCAGTTGCCCTTCGGCATGGGTCCGTTGGAGGGTCAGGTGGGAGGAGGAGGTTCACCACACCAGACGGATGCCCAGCTAAAGacggaggagcaggaggacgaggagcacAACTTGTCGGTCAAGTCGGAGGATAAGCTCAAAAGGGAGCCTTTGGTGAATGTGTCCGAAggcgatgaggaggaggatgtagaagatgaggaggaggaggaggaagaggctGAGAGTCGTCACAGCCAGCTGGACATGATGATCAAgtcggaggaggagaaggaggccAAGGTCAAGAAGGAGGACAAGAGCGAGGATCAAAGCGAAATGAAATCCGAGTCCGAGAGACTGGGCACTCCCGATCAGCAGCAAGTGGAGGATGATAGGAAATCCATTGATATTGTAAGCACACCACCGCCCACGGAGGCTCCTTctagcggcggcggcgatgcCCCGCTGGATCTCTCCATTTGCCGCAAGCGCCTGTCGTCCGGCTTCTTTCCCGCTCCGCCTGGCAGCCCTGGCAGCCTGCTCTCCACCAGCCTGATGCGTTTCCTGCCTTCCTCCAACCACCATGCCGAGGAGGATGAGACTGATGGCGAACCGGCGCTCAAGTTGCGGAAGTCACACAGTTCCGGGGAATCCTCGACCTCACAAAAGTCCTACAAGGGCAGCAGTCCCACGCCCACAGCCTCGCCGGGGCCCACACCCTCGCCCTCACCACCCACCAGTGCTGGGGGTGAGCTGAGCAGCATGTCCGAGGGAGCGGGAGCGGCGGCAGGTTCAAACTCTGGACTAGCAGCCgccgcggcagcagcagctgcagcagcggccgcTGGGGCCGCCGAGGCCGCCCTGGCCGCCCACTACAACCGCCAGAATCCACCCATTCACCCCATGATGCTGGAGGAGATCTATCGCAgtcggttttcttttttatgccCAGCGGGCGGACGGCCCGGCATTGAGGCTTTGCTGGCGGGAGCCGCCGCCGGCGCCGCCTCAAAGCGGCCGCTTCCGCCCGTTAAGTTCGCCACAACGGGAGGGGCAATGGGCTCCTCCTCGGTATCCGGCCATCCGCTGAAGACCAAGGATCGTTATACGTGCAAATTCTGCGGCAAGGTGTTCCCCCGCTCCGCCAATCTGACGCGGCATTTGAGGACGCACACCGGCGAGCAGCCGTATCCGTGCAAGTACTGCGACCGGGCCTTCAGCATCTCCTCCAATCTGCAGCGTCACGTCCGGAATATCCACAACAAGGAGCGTCCCTTTCGCTGCGAACTCTGCGATCGATCCTTTGGCCAGCAGACGAATCTCGATCGGCACGTGAAGAAGCACGAGGCGGAGGGCAGCAATTTCCGGGACTCGCCCAGCTCCGCCTCGGGCGTGGCCGAGCGGGAGGAGTACTTCGATGAGATCAGGACCTTCATGAACAGGGTCTACACGCCGAACAGTCTGGCGGGCAATGAGGGGGACACCGAGGAGGATGATCAGTCCTCGGTGATCCTAGAAAAGAAGTCGCAactcaacaataacaacaacaatagcagccACATTAGCAACAATAATCCCAAGTTGCTGTACTCGTGA
Protein Sequence: MLFDRYVISGSTGDDFDPSASAVRHHHRLDHHHLDHHLDHHHHHLDLSARTQAFAGLPLEQSLEESSPTREEQQQHHHQHHHHHHHQLQQLQQPPPPTLPLDSAVATGESGMEHFFKDPAQAEQILQEWARRREPISDLDIRESGVFAKTSLQRGTRYGPFPVKLCHQPNDSQLAWKAHAKHFNGWLEPTSDVSAWLKKIRVIEDHEMIAKANLESFINGGCLYYETNRYVSAGSEMIVDGRPKSPVQINESFMAGGGVLAAAAAAAAAVAAATSSSGSGSGSGGKSGKGSSVPSDDRSDRDNGDIDFTDDENGFDIRCEVCDKVYPDLELLDDHLVVAHHFKQDDYSCKLCPLRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGSYRQQQHQHQQSPLSRHHPHPHPYQQHPHPQHPHQLPASTHPAAATATSVGSAGPAGGDSTGGSVTSSSSSATAAVVAAMSTPPNPFLMFRTGAPFFPGFPPYGLPGIFPQSPLRAANFPLFFPNPPMDMGCGMPGMTSPNSAFRQQLPFGMGPLEGQVGGGGSPHQTDAQLKTEEQEDEEHNLSVKSEDKLKREPLVNVSEGDEEEDVEDEEEEEEEAESRHSQLDMMIKSEEEKEAKVKKEDKSEDQSEMKSESERLGTPDQQQVEDDRKSIDIVSTPPPTEAPSSGGGDAPLDLSICRKRLSSGFFPAPPGSPGSLLSTSLMRFLPSSNHHAEEDETDGEPALKLRKSHSSGESSTSQKSYKGSSPTPTASPGPTPSPSPPTSAGGELSSMSEGAGAAAGSNSGLAAAAAAAAAAAAAGAAEAALAAHYNRQNPPIHPMMLEEIYRSRFSFLCPAGGRPGIEALLAGAAAGAASKRPLPPVKFATTGGAMGSSSVSGHPLKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGSNFRDSPSSASGVAEREEYFDEIRTFMNRVYTPNSLAGNEGDTEEDDQSSVILEKKSQLNNNNNNSSHISNNNPKLLYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561894;
90% Identity: iTF_00527467;
80% Identity: -