Basic Information

Insect: Drosophila bocki
Gene Symbol: ham
Assembly: GCA_008042715.1
Location: VNJY01004126.1:22913-43900[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0058 0.42 11.0 0.0 2 23 307 329 306 330 0.92

2 9 0.003 0.21 12.0 2.1 1 23 336 359 336 359 0.94

3 9 1.4e-07 1e-05 25.6 1.7 1 23 365 388 365 388 0.96

4 9 8.9e-07 6.4e-05 23.1 1.6 1 23 394 416 394 416 0.97

5 9 2.3e-05 0.0017 18.6 3.3 1 23 422 444 422 444 0.97

6 9 0.00021 0.015 15.6 1.7 2 21 452 471 451 472 0.94

7 9 5.3e-09 3.8e-07 30.1 1.3 1 23 951 973 951 973 0.99

8 9 3.8e-07 2.7e-05 24.2 0.5 1 23 979 1002 979 1002 0.97

9 9 6e-06 0.00043 20.4 1.3 1 23 1008 1030 1008 1030 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0058	0.42	11.0	0.0	2	23	307	329	306	330	0.92
2	9	0.003	0.21	12.0	2.1	1	23	336	359	336	359	0.94
3	9	1.4e-07	1e-05	25.6	1.7	1	23	365	388	365	388	0.96
4	9	8.9e-07	6.4e-05	23.1	1.6	1	23	394	416	394	416	0.97
5	9	2.3e-05	0.0017	18.6	3.3	1	23	422	444	422	444	0.97
6	9	0.00021	0.015	15.6	1.7	2	21	452	471	451	472	0.94
7	9	5.3e-09	3.8e-07	30.1	1.3	1	23	951	973	951	973	0.99
8	9	3.8e-07	2.7e-05	24.2	0.5	1	23	979	1002	979	1002	0.97
9	9	6e-06	0.00043	20.4	1.3	1	23	1008	1030	1008	1030	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCCAGTGGCGACGACTTCGATCCGAGTGCTAGTGCTGTGCGTCACCACCATCGCCTGGATCACCATCACCTGGATCATCATTTGGATCAACATCATCTCGATCTCAGTGCCAGGAGTCAGGCCTTTGCTGGTCTGCCCTTGGAGCAATCCCTTGAAGAGCATTCTCCCACCAGGGAGGATCATCATCACCTACGCCAGCATCCgttgcagcagctccagcagccaCCGCCGCCCACGTTGCCCTTGGACTCGTCAGCAGCTGCCATTGCCGGTGAATCCGGTATGGAGCACTTCTTCAAGGATCCCTCCCAGGCGGAGCAGATTCTGCAGGAGTGGGCGAGACGCCGGGAACCCATCAGTGAACTGGACATCCGGGAAAGTGGTGTCTATGCCAAGACATCCTTGCAAAGGGGCACCCGCTATGGTCCCTTTCCCGTGAAGCTCTGCCATCAGCCCAACGATTCACAGCTGGCCTGGAGGGCCCATGCCGAGCACTTTAATGGCTGGCTAGAGCCCACATCTGATGTTTCCGGTTGGCTAAAGAAAATCCGCGTCATAGAGGACAACGAATTTATAGCCAAGGCCAATCTGGAGAGTTTCATTAATGGCGGTTGTctgTATTATGAAACGAATCGCTATGTGAGTGCCGGCAGCGAAATGATTGTGGATGGTCGACCCAAAAGTCCCGTGCAGATCAATGAGAGCTTCATGAACGGCGGCGGAGTCCTGgccgcagctgcagcagtGGCCGCAGTGGCTGCCGCCACATCCTCGTCGGCGGGATCGGGTGGAAAGAGCGGAAAAGGCTCATCGGTGCCCAGCGATGATCGCAGTGATCGTGAAAAtgGTGATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTGTTGGACGATCATCTGGTGGTTGCCCATCATTTCAAGCAGGACGACTACTCCTGCAAGCTCTGTCCTTTGCGATTCTGCCATCGTCCTTTGCTCATCAAGCACGAAGCGATCTCCCACAATAATATAAGGAAATATTCCTGCGAGAATTGCAGCAAGGTTTTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCACCCTTGTCCAGAGTGCGGAAAGACGTTCGGTACCTCGTCGGGGCTgaagcagcaccagcacatCCACAGCAGCGTGAAACCCTTCGCCTGCGAGGTGTGCTCCaaggcgtatacgcaattctCGAACCTGTGCCGCCACAAGCGGATGCACGCCACCTGCCGCACGCAGATCAAGTGCGACAAGTGCAATCAGAGCTTCAGCACCTTGACCTCGCTGACCAAGCACAAAAAGTTCTGTGATTCAACGGGCTCGtaccgccagcagcagcatcagcatcagcaccagcagTCGCCGCTAAGTCGCCACCacccgcatccgcatccGCATCCAGCAGCCGCCACAGTCACATCCGCCTCTGCAGTGCCTGCGGGAGGAGAGTCTACGGGAGGATCTGCCACTTCGTCTTCGTCTGCCACCGCTGCCGTTGTTGCCGCCATGTCAACGCCGCCGAATCCCTTCCTGATGTTCCGCACGGGAGCGCCATTCTTCCCCGGCTTCCCGCCGTACGGCCTGCCGGGAATGTTCCCGCAGAGTCCACTGAGAGCCGCCAACTTCCCGCTTTTCTTCCCCAATCCCCCCATGGACATGGGCTGCGGCATGCCCGGCATGACTTCGCCGAACTCTGCCTTCCGGCAGCAGTTGCCCTTCGGCATGGGACCCATGGAGGGTCAGGGAGGAGGAGGTTCACCACACCAGACGGATGCCCAGTTAAAGgcggaggaagaggagcaCAACTTGTCTGTGAAGTCGGAGGATAAGCTCAAGCGAGAGCCTCTGCTGAATGTGTCCGAAggcgatgaggaggaggctgaggacgaggaggaggacgaggctGAGAGTCGTCATAGCAATCTGGACATGACAATCAAAtcagaggaggagaaggaggccaAGGtcaagaaggaggagaagagcGAGGATCAAAGCGAAATGAAATCAGAACCCGAGAGACTGGGCAGCCCTGATCAGCAGCAGGTAGAGGATGATAGGAAATCCATTGATATTGTCAGCACTCCACCGCCCACGGATGCTCCTACTGCCGGCGATGCCCCGCTGGATCTCTCCATTTGCCGCAAGCGCCTGTCCGGTTACTTCCCGGCACCGCCTGGCAGTCCTGGTCTGCTCTCCTCCAGCCTTATGCGTTTCCTGCCCTCCACCAGAACCGAGGAGGATGAGACAGATGGCGAGCCGCCGCTCAAGACGCGGAAATCCCACAGTTCCGGCGAGTCCTCGACGTCGCAAAAGTCCTACAAGGGCAGCAGTCCCACGCCCACAGCCTCGCCGGGGCCCACACCCTCACCCTCACCTCCCACCAGTGCCGGGGGAGAGCTGAGCAGCATGTCCgagggagctggagctgggtcAGGATCGGGACTGGCTgccgcagcggcagcagcagcggctgcagcgGCCGCCGGAGCCGCCGAGGCAGCTCTGGCCGCCCACTATAACCGCCAGAATCCACCCATACACCCGATGGTGCTGGAGGAAATCTATCGCAGccggttttcttttttatgccCAGCGGGCGGACGGCCCGGCATTGAGGCTTTGCTGGCGGGAGCCGCCGCCGGCGCCGCCTCAAAGCGGCCGCTTCCGCCCGTTAAGTTCGCCACAGGGACAACTGTGGCCTCCTCCGTGGGCCATCCGCTAAAGACCAAGGATCGTTATACCTGCAAGTTTTGCGGCAAGGTGTTCCCCCGCTCGGCCAATCTCACCCGGCACCTGAGGACGCACACCGGCGAGCAGCCGTACCCGTGCAAATACTGCGACCGGGCCTTTAGCATCTCCTCCAATCTGCAGCGCCACGTGAGGAATATCCACAACAAGGAGCGACCCTTTCGCTGCGAACTCTGCGACCGATCCTTTGGCCAGCAGACGAATCTCGATCGGCATGTGAAGAAGCACGAGGCGGAGGGCAGTAACTTCCGGGACTCGCCCAGCTCTGCCTCGGGCGTGGCCGAGCGGGAGGAGTATTTCGATGAGATCAGGACCTTCATGAACAGGGTGTATACGCCAAACAGCCTGGCGGGAAACGAGGGGGACACCGAGGAGGATGACCAGTCCTCGGTGATCCTGGAGAAGAAGTCGCAcctcaacaacaataacaacagcagtcACATTAGCAACAATAATCCCAAGTTGCTGTATTCGTGA
Protein Sequence: MLFDRYVISGSSGDDFDPSASAVRHHHRLDHHHLDHHLDQHHLDLSARSQAFAGLPLEQSLEEHSPTREDHHHLRQHPLQQLQQPPPPTLPLDSSAAAIAGESGMEHFFKDPSQAEQILQEWARRREPISELDIRESGVYAKTSLQRGTRYGPFPVKLCHQPNDSQLAWRAHAEHFNGWLEPTSDVSGWLKKIRVIEDNEFIAKANLESFINGGCLYYETNRYVSAGSEMIVDGRPKSPVQINESFMNGGGVLAAAAAVAAVAAATSSSAGSGGKSGKGSSVPSDDRSDRENGDIDFTDDENGFDIRCEVCDKVYPDLELLDDHLVVAHHFKQDDYSCKLCPLRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRTQIKCDKCNQSFSTLTSLTKHKKFCDSTGSYRQQQHQHQHQQSPLSRHHPHPHPHPAAATVTSASAVPAGGESTGGSATSSSSATAAVVAAMSTPPNPFLMFRTGAPFFPGFPPYGLPGMFPQSPLRAANFPLFFPNPPMDMGCGMPGMTSPNSAFRQQLPFGMGPMEGQGGGGSPHQTDAQLKAEEEEHNLSVKSEDKLKREPLLNVSEGDEEEAEDEEEDEAESRHSNLDMTIKSEEEKEAKVKKEEKSEDQSEMKSEPERLGSPDQQQVEDDRKSIDIVSTPPPTDAPTAGDAPLDLSICRKRLSGYFPAPPGSPGLLSSSLMRFLPSTRTEEDETDGEPPLKTRKSHSSGESSTSQKSYKGSSPTPTASPGPTPSPSPPTSAGGELSSMSEGAGAGSGSGLAAAAAAAAAAAAAGAAEAALAAHYNRQNPPIHPMVLEEIYRSRFSFLCPAGGRPGIEALLAGAAAGAASKRPLPPVKFATGTTVASSVGHPLKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGSNFRDSPSSASGVAEREEYFDEIRTFMNRVYTPNSLAGNEGDTEEDDQSSVILEKKSHLNNNNNSSHISNNNPKLLYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561894;
90% Identity: iTF_00527467;
80% Identity: -