Basic Information

Insect: Drosophila burlai
Gene Symbol: ham
Assembly: GCA_008042655.1
Location: VNJT01017522.1:268907-292272[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0064 0.49 11.0 0.0 2 23 306 328 305 329 0.92

2 9 0.0033 0.25 11.9 2.1 1 23 335 358 335 358 0.94

3 9 1.6e-07 1.2e-05 25.5 1.7 1 23 364 387 364 387 0.96

4 9 9.8e-07 7.5e-05 23.0 1.6 1 23 393 415 393 415 0.97

5 9 2.6e-05 0.002 18.6 3.3 1 23 421 443 421 443 0.97

6 9 0.00023 0.018 15.5 1.7 2 21 451 470 450 471 0.94

7 9 5.9e-09 4.5e-07 30.0 1.3 1 23 972 994 972 994 0.99

8 9 4.2e-07 3.2e-05 24.2 0.5 1 23 1000 1023 1000 1023 0.97

9 9 6.7e-06 0.00051 20.4 1.3 1 23 1029 1051 1029 1051 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0064	0.49	11.0	0.0	2	23	306	328	305	329	0.92
2	9	0.0033	0.25	11.9	2.1	1	23	335	358	335	358	0.94
3	9	1.6e-07	1.2e-05	25.5	1.7	1	23	364	387	364	387	0.96
4	9	9.8e-07	7.5e-05	23.0	1.6	1	23	393	415	393	415	0.97
5	9	2.6e-05	0.002	18.6	3.3	1	23	421	443	421	443	0.97
6	9	0.00023	0.018	15.5	1.7	2	21	451	470	450	471	0.94
7	9	5.9e-09	4.5e-07	30.0	1.3	1	23	972	994	972	994	0.99
8	9	4.2e-07	3.2e-05	24.2	0.5	1	23	1000	1023	1000	1023	0.97
9	9	6.7e-06	0.00051	20.4	1.3	1	23	1029	1051	1029	1051	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCCACTGGCGACGACTTCGATCCGAGTGCTAGTGCTGTGCGTCACCACCATCGCCTGGATCACCATCACCTGGATCACCATCtggatcatcatcatctcgaTCTCAGTGCCAGGAGCCAGGCCTTTGCTGGTTTGCCCTTGGATCAGTCCCTCGAAGAACGTTCTCCCACCAGGGAGGAGCATCATCACCACCGCCAGCTTCAgttgcagcagctccagcagccaccgccgcccacgTTGCCCTTGGACTCGGTAGTAGCCGGCGAGTCCGGTATGGAGCATTTCTTCAAGGACCCCGCCCAGGCGGAGCAGATCCTGCAGGAGTGGGCGAGGCGCCGGGAGCCCATCAGTGATCTGGACATCCGGGAGAGCGGTGTCTATGCCAAGACCTCCCTGCAGAGGGGCACCCGCTATGGTCCCTTTCCTGTAAAGCTGTGCCATCAGCCCAACGATGCACAGCTGGCCTGGAAGGCCCATGCCGAGCACTTCAATGGCTGGCTAGAGCCCACATCCGATGTCTCAGCTTGGCTGAAGAAAATCCGCGTCATAGAAGACCACGACATGATAGCCAAAGCCAATCTGGAGAGTTTCATTAATGGCGGTTGTctCTATTACGAAACGAATCGTTATGTGAGTGCCGGCAGCGAAATGATTGTGGATGGTCGACCCAAGAGTCCCGTGCAGATTAATGAGAGCTTCATGGCCGGCGGCGGGGTCCTggccgcagctgcagcagcagcggccgccGTAGCCGCCGCCACATCCTCGTCAGGATCGGGATCGGGCGGAAAGAGCGGCAAGGGGTCATCGGTGCCCAGCGATGATCGCAGTGATCGTGATAATGGTGATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTGTTGGACGATCATCTGGTGGTTGCCCATCATTTCAAGCAGGACGACTACTCCTGCAAGCTCTGTCCGCTGCGATTCTGCCATCGTCCTTTGCTCATCAAGCACGAAGCGATCTCCCACAATAATATAAGGAAATATTCCTGCGAGAATTGCAGTAAGGTTTTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCACCCTTGTCCGGAGTGCGGAAAGACGTTCGGTACCTCGTCGGGGCTgaagcagcaccagcacaTCCACAGCAGCGTGAAGCCCTTCGCCTGCGAGGTGTGCTCCaaggcgtatacgcaattcTCGAACCTGTGCCGCCACAAGCGGATGCACGCCACCTGCCGCATGCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACCCTGACCTCGCTGACCAAGCACAAAAAGTTCTGTGATTCGACGGGCTCGtaccgccagcagcagcagcatcagcaccagcagtCGCCGCTGAGTCGCCaccatccgcatccgcatccgtacCAGCAGCACCCGCATCCGCAGCATCCCCACCAGCATCCCGCTTCGACGCATCCGGCAGCCGCCACAGCCACATCGGGATCTGCAGGGCCAGCGGGAGGAGAGTCCACGGGAGGATCGGCCACTTCGTCTTCGTCTGCCACCGCTGCCGTAGTTGCCGCCATGTCAACGCCACCGAATCCCTTCCTCATGTTCCGCACGGGAGCGCCGTTCTTCCCCGGCTTTCCGCCCTATGGACTGCCGGGTATCTTCCCGCAGAGTCCCCTGAGAGCCGCCAACTTCCCGCTTTTCTTCCCCAATCCCCCCATGGACATGGGCTGCGGCATGCCCGGCATGACCTCGCCGAACTCCGCCTTTCGGCAGCAGTTACCCTTCGGCATGGGACCCCTGGAGGGCCAGGTGGGAGGAGGTTCACCACACCAGACGGATGCCCAGCtgaaggcggaggaggaggagcacaaCTTGTCGGTCAAGTCGGAGGATAAGCTGAAGAGGGAGCCCTTGCTGAATGTCTCCGAAGgcgatgaggaggaggtggaggatgaggaggaggaagaggctGAGAGTCGACACAGCAACCTGGACATGAGGATCAAgtcggaggaggagaaggaggccAAGGTCAAGAAGGAGGACAAGAGCGAGGAGCGAAGCGAAATGAAATCGGAGCCCGAGAGACTGGGCAGTCCCGATCAGCAGCAAGTGGAGGATGATAGGAAATCCATTGATATTGTGAGCACACCACCGCCCACGGATGCTCCTTCTACCGGCGGTGATGCCCCGCTGGATCTTTCCATTTGCCGCAAGCGCCTGTCCGGCTTCTTTCCGGCTCCACCTGGCAGCCCCAGCCTGCTCTCCTCAAGCCTGATGCGTTTCCTGCCTTCCAACCAAACCGAGGAGGATGAGACCGATGGCGAGCCGCCGCTCAAGTTGCGCAAGTCCCACAGTTCCGGCGAGTCCTCGACCTCGCAAAAGTCCTACAAGGGCAGCAGTCCCACGCCCACAGCCTCGCCGGGGCCGACACCTTCACCCTCACCACCCACCAGTGCCGGGGGTGAGCTGAGCAGCATGTCCGAGGGAGCGGGAGTGGGTTCCGGAGCAGGTTCGGGATCTggactggcggcggcggcagcagcagcagcggcagcggccgCCGGAGCCGCCGAGGCCGCACTGGCCGCCCACTACAACCGCCAGAATCCACCCATTCACCCCATGATGCTGGAGGAGATCTATCGCAGccggttttcttttttatgccCAACGGGCGGACGGCCCGGCATTGAGGCTTTGCTGGCGGGAGCCGCCGCCGGCGCCGCCTCAAAGCGGCCGCTTCCGCCCGTGAAGTTCGCCACAGGGGCAACGGGCTCGGCGGGCTCCTCGGTGGGCCATCCGCTGAAGACCAAGGATCGTTACACCTGCAAGTTCTGCGGCAAGGTGTTCCCCCGCTCGGCCAATCTCACGCGGCACCTGAGGACGCACACCGGCGAGCAGCCGTACCCGTGCAAGTACTGCGACCGGGCCTTCAGCATCTCCTCCAATCTGCAGCGCCACGTGAGGAATATCCACAACAAGGAGCGCCCCTTTCGCTGCGAACTCTGCGACCGATCCTTTGGCCAGCAGACGAATCTCGATCGGCACGTGAAGAAGCACGAGGCGGAGGGCAGCAACTTCCGGGACTCGCCCAGCTCCGCCTCGGGCGTGGCCGAGCGGGAGGAGTACTTCGATGAGATCAGGACCTTCATGAACAGGGTCTACACGCCGAACAGCCTGGCGGGTAATGAGGGGGACACCGAGGAGGATGAGCAGTCCTCGGTGATCCTCGAGAAGAAGTCGCacctcaacaacaacaacagcagccacatTAGCAACAACAATCCCAAGTTGCTGTACTCGTGA
Protein Sequence: MLFDRYVISGSTGDDFDPSASAVRHHHRLDHHHLDHHLDHHHLDLSARSQAFAGLPLDQSLEERSPTREEHHHHRQLQLQQLQQPPPPTLPLDSVVAGESGMEHFFKDPAQAEQILQEWARRREPISDLDIRESGVYAKTSLQRGTRYGPFPVKLCHQPNDAQLAWKAHAEHFNGWLEPTSDVSAWLKKIRVIEDHDMIAKANLESFINGGCLYYETNRYVSAGSEMIVDGRPKSPVQINESFMAGGGVLAAAAAAAAAVAAATSSSGSGSGGKSGKGSSVPSDDRSDRDNGDIDFTDDENGFDIRCEVCDKVYPDLELLDDHLVVAHHFKQDDYSCKLCPLRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGSYRQQQQHQHQQSPLSRHHPHPHPYQQHPHPQHPHQHPASTHPAAATATSGSAGPAGGESTGGSATSSSSATAAVVAAMSTPPNPFLMFRTGAPFFPGFPPYGLPGIFPQSPLRAANFPLFFPNPPMDMGCGMPGMTSPNSAFRQQLPFGMGPLEGQVGGGSPHQTDAQLKAEEEEHNLSVKSEDKLKREPLLNVSEGDEEEVEDEEEEEAESRHSNLDMRIKSEEEKEAKVKKEDKSEERSEMKSEPERLGSPDQQQVEDDRKSIDIVSTPPPTDAPSTGGDAPLDLSICRKRLSGFFPAPPGSPSLLSSSLMRFLPSNQTEEDETDGEPPLKLRKSHSSGESSTSQKSYKGSSPTPTASPGPTPSPSPPTSAGGELSSMSEGAGVGSGAGSGSGLAAAAAAAAAAAAGAAEAALAAHYNRQNPPIHPMMLEEIYRSRFSFLCPTGGRPGIEALLAGAAAGAASKRPLPPVKFATGATGSAGSSVGHPLKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGSNFRDSPSSASGVAEREEYFDEIRTFMNRVYTPNSLAGNEGDTEEDEQSSVILEKKSHLNNNNSSHISNNNPKLLYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561894;
90% Identity: iTF_00527467;
80% Identity: -