Basic Information

Insect: Drosophila bakoue
Gene Symbol: ham
Assembly: GCA_008044335.1
Location: VNJL01010577.1:3240-14553[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0044 0.53 11.5 0.0 2 23 14 36 13 37 0.92

2 9 0.0022 0.27 12.4 2.1 1 23 43 66 43 66 0.94

3 9 1.1e-07 1.3e-05 26.0 1.7 1 23 72 95 72 95 0.96

4 9 6.7e-07 8.1e-05 23.5 1.6 1 23 101 123 101 123 0.97

5 9 1.7e-05 0.0021 19.0 3.3 1 23 129 151 129 151 0.97

6 9 0.00016 0.019 16.0 1.7 2 21 159 178 158 179 0.94

7 9 4e-09 4.8e-07 30.5 1.3 1 23 683 705 683 705 0.99

8 9 2.9e-07 3.4e-05 24.6 0.5 1 23 711 734 711 734 0.97

9 9 4.6e-06 0.00055 20.9 1.3 1 23 740 762 740 762 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0044	0.53	11.5	0.0	2	23	14	36	13	37	0.92
2	9	0.0022	0.27	12.4	2.1	1	23	43	66	43	66	0.94
3	9	1.1e-07	1.3e-05	26.0	1.7	1	23	72	95	72	95	0.96
4	9	6.7e-07	8.1e-05	23.5	1.6	1	23	101	123	101	123	0.97
5	9	1.7e-05	0.0021	19.0	3.3	1	23	129	151	129	151	0.97
6	9	0.00016	0.019	16.0	1.7	2	21	159	178	158	179	0.94
7	9	4e-09	4.8e-07	30.5	1.3	1	23	683	705	683	705	0.99
8	9	2.9e-07	3.4e-05	24.6	0.5	1	23	711	734	711	734	0.97
9	9	4.6e-06	0.00055	20.9	1.3	1	23	740	762	740	762	0.98

Sequence Information

Coding Sequence: GATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTGTTGGACGATCATCTGGTGGTTGCCCATCATTTCAAGCAGGACGACTACTCCTGCAAGCTCTGTCCGCTGCGATTCTGCCATCGTCCTTTGCTCATCAAGCACGAAGCCATCTCCCACAAtaatataaggaaatattCCTGCGAGAATTGCAGCAAGGTTTTCTGTGACCCCTCGAATCTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCACCCTTGTCCGGAGTGCGGAAAGACGTTCGGTACCTCGTCGGGGCtgaagcagcaccagcacatCCACAGCAGCGTGAAGCCCTTCGCCTGCGAGGTCTGCTCCAAGGCGTACACGCAATTCTCGAACCTGTGCCGCCACAAGCGGATGCACGCCACCTGCCGCATGCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACCCTGACCTCGCTGACCAAGCACAAAAAGTTCTGTGATTCGACGGGCTCGtaccgccagcagcagcaccagcatcagcaccagcagtCGCCGCTGAGCCGCcaccatccgcatccgcatccgtaccagcagcatccgcatccgcatcagcATCCCGCTGCTTCGACGCATCCGGCAGCCGCCACAGCCACATCTGGGTCTGCAGGGCcagcgggaggaggaggagagtcCACGGCAGGATCGGCCACTTCATCGTCgtctgccaccgccgccgtaGTTGCCGCCATGTCAACGCCACCGAATCCCTTCCTGATGTTCCGCACGGGAGCGCCATTCTTCCCCGGCTTTCCGCCCTATGGACTGCCTGGTATCTTCCCGCAGAGTCCCCTGAGAGCCGCCaatttcccgcttttcttcCCCAATCCCCCGATGGACATGGGCTGCGGCATGCCCGGCATGACCTCGCCGAACTCCGCCTTCAGGCAGCAGTTGCCCTTCGGCATGGGACCCTTGGAGGGTCAGGTGGGAGGAGTCTCACCACACCAGACAGATGCCCAGTtgaaggcggaggaggaggaggagcacaaCTTGTCGGTCAAGTCGGAGGATAAGCTCAAGCGGGAGCCTTTGCTGAATGTGTCCGAAGGCGATGAGGAGGATgttgaggatgaggaggaggaagaggctGAGAGTCGTCATAGCAACCTGGACATGATGATCAAgtcggaggaggagaaggaggccAAGGTCAAGAAGGAGGACAGGAGCGAGGAGCAGAGCGAGGAGCAGAGCGAGATGAAATCAGAGCCAGAGAGGCTGGGCAGTCCCGATCAGCAGCAGGTGGAGGATGATAGGAAATCCATTGATATTGTGAGCACACCACCGCCCACGGATGCCCCTTCTGCCGGCGGCGATGCCCCGCTGGATCTCTCCATTTGCCGCAAGCGCCTGTCCGGCTTCTTTCCGGCTCCGCCTGGCAGCCCCAGCCTGCTCTCCTCCAGCCTGATGCGTTTCCTGCCCTCCACCCAAACCGAGGAGGATGAGACTGATGGCGAGCCGCCGCTCAAGTTGCGCAAATCCCACAGTTCCGGCGAGTCCTCGACCTCGCAAAAGTCCTACAAGGGCAGCAGTCCCACGCCCACAGCCTCGCCGGGGCCCACGCCTTCACCCTCACCACCCACCAGTGCCGGGGGTGAGCTGAGCAGCATGTCCGAGGGAGCGGGAGTGGGTTCCGGAGCAGGTTCCGGATCTGgactggcagcggcggcagcagcagcggcagcggccgcCGGAGCCGCCGAGGCCGCTCTGGCCGCCCACTACAACCGCCAGAATGCACCACCCATTCACCCCATGATGCTGGAGGAGATCTATCGCAAccggttttcttttttatgccCAGCGGGCGGACGGCCCGGCATTGAGGCTTTGCTGGCGGGAGCCGCCGCCGGCGCCGCCTCAAAGCGGCCGCTTCCGCCCGTGAAGTTCGCCACAGGGGCAACGGGCTCCTCAGTGGGCAATCCGCTGAAGACCAAGGATCGTTACACCTGCAAGTTCTGCGGCAAGGTGTTCCCCCGCTCCGCGAATCTCACGCGGCACCTGAGGACGCACACCGGCGAGCAGCCGTACCCGTGCAAGTACTGCGACCGGGCCTTCAGCATCTCCTCCAATCTGCAGCGCCACGTGAGGAATATCCACAACAAGGAGCGACCCTTTCGCTGCGAACTCTGCGACCGATCCTTTGGCCAGCAGACGAATCTCGATCGGCACGTGAAGAAGCACGAGGCGGAGGGCAGCAACTTCCGGGACTCGCCCAGCTCCGCCTCGGGCGTGGCCGAGCGGGAGGAGTACTTCGATGAGATCAGGACCTTCATGAACAGGGTCTACACGCCGAACAGTCTGGCGGGTAATGAGGGGGACACCGAGGAGGATGACCAGTCCTCGGTGATCCTCAAGAAGAAGTCGCAccttaacaacaacaacaacaatagcagccACATTAGCAACAATAATCCCAAGTTGCTGTACTCGTGA
Protein Sequence: DIDFTDDENGFDIRCEVCDKVYPDLELLDDHLVVAHHFKQDDYSCKLCPLRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGSYRQQQHQHQHQQSPLSRHHPHPHPYQQHPHPHQHPAASTHPAAATATSGSAGPAGGGGESTAGSATSSSSATAAVVAAMSTPPNPFLMFRTGAPFFPGFPPYGLPGIFPQSPLRAANFPLFFPNPPMDMGCGMPGMTSPNSAFRQQLPFGMGPLEGQVGGVSPHQTDAQLKAEEEEEHNLSVKSEDKLKREPLLNVSEGDEEDVEDEEEEEAESRHSNLDMMIKSEEEKEAKVKKEDRSEEQSEEQSEMKSEPERLGSPDQQQVEDDRKSIDIVSTPPPTDAPSAGGDAPLDLSICRKRLSGFFPAPPGSPSLLSSSLMRFLPSTQTEEDETDGEPPLKLRKSHSSGESSTSQKSYKGSSPTPTASPGPTPSPSPPTSAGGELSSMSEGAGVGSGAGSGSGLAAAAAAAAAAAGAAEAALAAHYNRQNAPPIHPMMLEEIYRNRFSFLCPAGGRPGIEALLAGAAAGAASKRPLPPVKFATGATGSSVGNPLKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGSNFRDSPSSASGVAEREEYFDEIRTFMNRVYTPNSLAGNEGDTEEDDQSSVILKKKSHLNNNNNNSSHISNNNPKLLYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561894;
90% Identity: iTF_00527467;
80% Identity: -