Dhaw000480.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila hawaiiensis
Gene Symbol
ken1
Assembly
GCA_037043685.1
Location
JBAMBA010000022.1:792354-794781[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0076 0.5 10.9 5.0 3 23 261 281 260 281 0.97
2 12 0.0001 0.0067 16.8 0.4 1 23 287 312 287 312 0.95
3 12 0.0012 0.082 13.3 0.7 1 23 319 344 319 344 0.93
4 12 0.00058 0.038 14.4 5.1 1 23 354 376 354 376 0.97
5 12 0.00019 0.013 15.9 1.8 2 23 384 405 383 405 0.96
6 12 0.0026 0.17 12.3 0.1 1 23 411 433 411 433 0.98
7 12 0.031 2 9.0 1.4 1 23 439 462 439 462 0.97
8 12 0.0046 0.31 11.5 3.2 1 23 468 490 468 490 0.96
9 12 0.00013 0.0085 16.4 1.2 2 23 497 518 496 518 0.98
10 12 0.00018 0.012 16.0 0.8 1 23 590 613 590 613 0.95
11 12 0.12 7.9 7.1 1.5 1 21 619 638 619 641 0.72
12 12 8.2e-06 0.00054 20.2 2.3 1 23 647 670 647 670 0.98

Sequence Information

Coding Sequence
atgaatgaggGGAGTGAATACTCCATTCACTCAATATGCCGAATCTGCTTAAATCACCTGCGAAATGATCCGGCGTACGACCTGTTTCTCGTTCCGGGTCTGGCCaaaaaactgtgtgtgtgtacttcaCTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCACCAATTGCTACACCAAGCTGAACGACTTGCACGGATTCCAGAAACTGTGCGTGGACTCTGTACAAAAGTTTCAGGAAATGGTCGCTAGCAATTATTTCGTACCCGTTGCTGGTGATATTGATAAAGTCGATATGCTGACTGGGGCGCCGGTCGATGGGGAAGCGGATGACGATAACATCAACTTTGATCCGCTTCTGAATACCAAGATAGAAATTGTGGAGACTGAGGAGgatgtttttaaaatgctaGATGATGTCGACAAGGAAGCAGAGGAGGTTGAGAAGGAAGTAGAGAGGGAGGTAGAGAGGGCAAAGGATATATCCAGTGATAGTGACAAcgacaatgataatgataatgatgacgatAGGGACGTTGACTTTCAAGTGAATAGTAGCGATACTGACGACGCCGTACCCTTGTCCCGCTTACGTAGTTCAACCAGGGCAAAAACGACAAAGGCCAAAACGAATACTGCGGATGACGATGAAGATGATTCCTCTAGCTTTGAATGGGCTGAGGATAAAGAGGATGATTTGGATAAACCCAAGCCAAAGCCAAGACGAAAACGCGTTCAAGTAGCTTCGGCACCCATCGATGGACTGGTTGACTGTCACATTTGTCAGGAAAAATTCAAGAGCACCAAACTCTACGAGGAACACATGAAACATCACAACGATCAATTGCCATTCCAGTGCTCTGTTGAAGACTGCAAGAAGGGTTTCACTACTGCTGGTGGTCTGCGCCTTCACATGGACCACGCCCATTCAGAATTCTCTGAAGTGCACGCCTGCACTGCTGAGGGGTGTGATAAGACCTTTCCTCGATCTGTCTTACTCACGTTCCATATGAAAAAGGTGCACAACATTATCAAGACACCGTCGCGGAATCATCCGTGCACGGAATGCGACAAAGTCTTCCGTTGTTCAACAGCACTCAAGAAGCACATGTATAAACACACTGGCGAAGAGAAGCCAATCTCCTGTAACATCTGTAACAAACGTTTTCACATAAACAGCGATCTCAGAGATCATCTTTTACGCCATGCCGGCGTGAAGAACTATGTGTGTCCATATTGCGGCGTGGGCAAAACTACTCGTCAGGAATGGAACAAACACATACTGACCCACACCAAAGAAAAACAGTTCCAGTGTCTCCAGTGCGATCATGCCTCGCATAACAAACAGGCTCTGGCCAATCATGTCAAGGTGGTTCATATGAAGATCAAGGACTTTGCCTGTCAGTATTGCGGCAAAACGTTTGGGAAGTCGTATTCGTGCAAAGTTCACGAGAGACTCCACACGGGCGAGAACTGCAGCAAGTGCAAGATCTGTGGCAAGGTGTTTCTTTTCGAGAAGGGATTGACCAAACATTTAAAGACCCATGAGAAGCGCGATAAAACACGGTCTGCTTCTGCGACTGCAGTCAAACCGAAGGACGATGGAGTCGCGCAAGGCACACAAAACACTATCCAAGAATTGCCTCAGCTAGTGGACGGGAAAGTCGTTCCAGAAGTTTCCACCAAGCCGAAGACATCAAATAGATATCGGTTCCCTCCCTGGTCGCCGCAAGTCAACTTCACAAAGAAGGAAGGCCAGCATATTTGTCCAGGATGTGGACGTGGTTTCAATCACATTGGCAATATGAAGCTCCACTACAAGATAATACACGAGAAGGTGAAGGACTTTGCCTGTCGCTTTTGTCCGAAGCGTTTTTCGAAGGCACAAATTTTGAAACATCATGAATGGGTTCACACTGGCGAGAAACCGTACGAGTGCAAGGTTTGCGGCAAACACTTCCGGCAGGAGTCAGTTATGAAGAACCATTTGAGAAGAGTGCACGAGAATGCGAAACCTGCAAAGGAGCCGAAACCACCAAAGACTGTTCTTAGGCCAACTGGACCACACGTCttgctcaacaaaaaacacgtCCTAAAGAATTTTGATGAGTACCAGGATCCTGCTGCAGAGCAAGccgctgcgactgctgcattGCTTGCCCAACAGCAGGAAGAGAATGAAGCGAAGCGAAGGGCTGAAGAAGAAACTCGCAAGATTCAGGAGGCTGCATGTGAACAACTTCAAAGGCTGCAGAAGGAGCAACTTATCGAGAAGATATCCATTAACAGCTTTCAAGTAAAAAGATCCGAATCGGGTGTCACTGTGGATGACCTCAAAGTAGATAATACACAGAAAGAATAA
Protein Sequence
MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLHGFQKLCVDSVQKFQEMVASNYFVPVAGDIDKVDMLTGAPVDGEADDDNINFDPLLNTKIEIVETEEDVFKMLDDVDKEAEEVEKEVEREVERAKDISSDSDNDNDNDNDDDRDVDFQVNSSDTDDAVPLSRLRSSTRAKTTKAKTNTADDDEDDSSSFEWAEDKEDDLDKPKPKPRRKRVQVASAPIDGLVDCHICQEKFKSTKLYEEHMKHHNDQLPFQCSVEDCKKGFTTAGGLRLHMDHAHSEFSEVHACTAEGCDKTFPRSVLLTFHMKKVHNIIKTPSRNHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSDLRDHLLRHAGVKNYVCPYCGVGKTTRQEWNKHILTHTKEKQFQCLQCDHASHNKQALANHVKVVHMKIKDFACQYCGKTFGKSYSCKVHERLHTGENCSKCKICGKVFLFEKGLTKHLKTHEKRDKTRSASATAVKPKDDGVAQGTQNTIQELPQLVDGKVVPEVSTKPKTSNRYRFPPWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILKHHEWVHTGEKPYECKVCGKHFRQESVMKNHLRRVHENAKPAKEPKPPKTVLRPTGPHVLLNKKHVLKNFDEYQDPAAEQAAATAALLAQQQEENEAKRRAEEETRKIQEAACEQLQRLQKEQLIEKISINSFQVKRSESGVTVDDLKVDNTQKE